• Journal of Korean Medicine for Obesity Research
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• v.12 no.1
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• pp.9-19
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• 2012

Objectives This study was designed to find out the relationships between obesity and growth, skeletal maturity among children by analyzing body composition and bone age. Methods Subjects were composed of 577 children from six years to seventeen years of age, without any other diseases related to growth, were measured their body composition and bone age. Results As obesity index was increased, the RH-MPH(%) and skeletal maturity significantly was also increased. The RH-MPH(%) of the obesity group was significantly increased than that of normal weight group; the skeletal maturity was more increased in th obesity group. It means the recent height of obese children was more taller than that of inherited from the parents, while skeletal maturity of obese children was more rapidly progressing. The RH-MPH(%) was increased in children who revealed stage of second sexual character; skeletal maturity was decreased in children who developed secondary sexual character. Conclusions Obesity children might be taller than what it supposed to be. However, obesity could cause the increase of skeletal maturity. It means the growth plate of obese children has been closed early.

• Journal of Korean Medicine for Obesity Research
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• v.6 no.2
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• pp.85-94
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• 2006

Objectives : To examine the correlation between obesity and blood pressure, smoking and drinking (define drinking: do you mean alcohol?) habit in adolescence. Methods : Data collected on 524 subjects from among Kyungwon University students who had participated in a health screening test were reviewed. With the exception of 20 subjects whose health status was deemed to be abnormal based on current illness or results of the health screening test, 504 healthy cases were analysed. We investigated the correlation between obesity as defined by BMI and blood pressure, smoking and drinking habit. Results : 1. The blood pressure of the obese group was high. 2. blood pressure was higher in smokers, and drinking did not influence blood pressure. 3. Smoking had an effect on obesity and drinking had no significant effect on obesity. Conclusions : Obesity is related to blood pressure and smoking habit. Drinking had no significant effect on obesity and blood pressure in this sample.

• Biomedical Science Letters
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• v.24 no.1
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• pp.23-29
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• 2018

Abdominal obesity is considered as one of the most risky factors governing the development of metabolic diseases. Here we identify that human chitinase 3-like 1 (CHI3L1, also called YKL-40 in human) single nucleotide polymorphism (SNP), rs883125, is associated with abdominal obesity in Korean women. Korean women subjects with the rs883125 G/G or C/G genotype present higher waist-hip ratio than subjects with C/C genotype suggesting that human subjects who G nucleotide substitution at the rs883125 tended to more accumulate intra-abdominal fat at the abdominal cavity. In addition, Chi3l1 gene expression is increased in adipose tissue from obese mice and pro-inflammatory cytokine enhances Chi3l1 expression in adipocytes, indicating that Chi3l1 is greatly related with obesity and obesity-induced pro-inflammatory responses. Taken together, the minor allele of rs883125 is associated with a higher prevalence of abdominal obesity in Korean women. These findings suggest that genotype of rs883125 can be a biomarker of incident abdominal obesity and abdominal obesity-related metabolic diseases.

• Journal of Korean Medicine for Obesity Research
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• v.22 no.2
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• pp.147-157
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• 2022

Objectives: The purpose of this study is to research domestic and foreign trend of pharmacopuncture treatment on obesity during recent 10 years. Methods: 5 Databases (Korean Studies Information Service System, Research Information Sharing Service, Oriental Medicine Advanced Searching Integrated System, Scopus, PubMed) were searched with keywords of ('pharmacopuncture', 'herbal acupuncture', 'aquapuncture', 'obesity') from 2012 to 2022. Results: 25 Articles were selected and analyzed. 15 articles (60%) were animal experimentations, 8 articles (32%) were case reports, 1 article (4%) was cell experimentation, and 1 article (4%) was clinical trial. In this study, 25 articles were analyzed by subject, acupoints, injections, metrics and results. Pharmacopuncture treatment for obesity is continuously being studied, and the anti-inflammatory effect as well as the effect of reducing obesity factors has been revealed. Conclusions: This study suggests the efficacy and future development of pharmacopuncture for obesity. The studies of the past decade have been concentrated on animal experiments, so many clinical trials and various studies on new complex pharmacopuncture for obesity are expected.

• Journal of Korean Medicine for Obesity Research
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• v.24 no.1
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• pp.13-24
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• 2024

Objectives: The objective of this study was to explore the anti-obesity effect of Cydonia oblonga Miller fruit extract (COME) and to compare its anti-obesity efficacy with Garcinia cambogia extract (GCE) in diet-induced obese mice. Methods: Five-week-old male C57BL/6 were allocated into four groups: control diet (CD), high-fat diet (HFD), HFD + 400 mg/kg body weight (BW)/day COME (H+C), or HFD + 400 mg/kg BW/day GCE (H+G) groups. COME or GCE was administered once a day by oral gavage for eight weeks. Body weight, body fat percentage, fat weight, and biochemical parameters in serum were measured. The expressions of transcription factors and their target genes in epididymal adipose tissues were analyzed by reverse transcription polymerase chain reaction. Results: COME reduced body weight, weight gain, body fat percentage, total white adipose tissue weight, adipocyte size, and serum levels of insulin and leptin in high-fat diet-induced obese C57BL/6 mice. COME suppressed the mRNA expressions of CCAAT/enhancer binding proteinα, peroxisome proliferator-activated receptorγ, sterol-regulatory element-binding protein-1c, fatty acid synthase, and adipocyte protein 2 and increased carnitine palmitoyl transferase 1 mRNA expression in epidydimal adipose tissues. The anti-obesity efficacy of COME was found to be similar to that of GCE at the same dose. However, COME more effectively decreased adipose tissue weights, epididymal adipocyte size, serum insulin and leptin compared to GCE. Conclusions: These results demonstrated that COME is not toxic and exhibits anti-obesity efficacy at a level similar to that of GCE, suggesting that COME may be applicable as an anti-obesity agent.

• Journal of Korean Medicine for Obesity Research
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• v.16 no.1
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• pp.50-63
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• 2016

Objectives: The aim of this study is to analyze methods and outcomes about fasting for obesity in korea medicine research. Methods: We searched the studies with key words of 'obesity' and 'fasting or starvation' in Korean database (Korean traditional knowledge portal, OASIS, KISS, KMBASE, DBPIA, RISS). Studies were analyzed for contents, evaluation methods and adverse effects. Results: Twenty-one studies were reviewed. Studies were published in 1983~2015. 1. Studies can be classified into three types: comparative study on before and after, comparative study between groups, case study on other disease occurred during the fasting therapy period. 2. The most common step of fasting were 3 steps: reducing food intakes period (3~5 days), fasting period (7~10 days) and refeeding period (3~5 days) and additional period-diet period (28 days). 3. The most common evaluation methods were body weight (BW), body fat mass (BFM), muscle weight (MW), fat free mass, body mass index, body fat percentage, etc. 4. BW, BFM, MW were reduced largely in fasting period. 5. The most common adverse effects were fatigue, nausea, headache, vomiting, insomnia, etc. Conclusions: As a result of the review papers, fasting therapy have positive effects for obesity. To verify the effectiveness of the fasting, more studies are needed such as randomized controlled trial.

• Journal of Korean Medicine for Obesity Research
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• v.9 no.2
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• pp.21-32
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• 2009

Objectives Identification of individuals predisposed to obesity is an important issue for prevention and control of the obesity. It was reported that a high prevalence of obesity appeared in Taeumin among Sasang constitutions, but Enneagram personality-types has not been used to classify the patterns of obesity. These two classification methods were employed in combination in the current study, and it was analyzed whether the morbidity pattern of obesity can be characterized in further detail. Methods The subjects were 125 University students(62 males and 63 females) who answered both questionnaires for Sasang constitutions and Enneagram personality types. The obesity of students was classified by the obesity index and BMI. Results Only Taeumin group of Sasang constitutions was overweight, and the male of the group was overweight or obese. Analysis of the obesity index and BMI according to the Enneagram personality types showed significant differences(p<.05) between the types in the female group. These values were highest at the type 3 and lowest at the type 4. The physical indices according to both the centers of Enneagram and Sasang constitutions showed that only Taeumin female group had significant differences(p<.05) in the obesity index and BMI. Taeumin male group was overweight or obese in all centers of Enneagram and Taeumin female group was overweight or obese only in heart-center. Conclusions Diagnosis of the present data suggest that the classification of obesity patterns using Enneagram personality types in addition to Sasang constitutions is very useful to prevent and control the obesity.

• Korean Journal of Acupuncture
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• v.30 no.3
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• pp.151-160
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• 2013

Objectives : The purpose of this study is to review the thread embedding treatment studies of obesity in Traditional Chinese Medicine. Methods : We reviewed 59 studies on cat-gut-embedding treatment of obesity which were published from 2005 to 2012. The studies were searched using the data base-CAJ(China Academic Journals; 中國期刊全文數據庫)(2005~2012). Results : Selected 59 studies were divided into 27 case series and 32 control studies. The number of studies has increased since 2005, more rapidly in 2011~2012. Most case series reported were about effectiveness of thread embedding monotherapy treating obesity. Control studies reported were about effectiveness of thread embedding treatment compared with acupuncture, electroacupuncture, and medicine. Most studies on thread embedding treatment of obesity showed that its effectiveness was very good. Conclusions : There have been many reports of thread embedding treatment studies of obesity in Traditional Chinese Medicine. We believed that these studies could be applied to the clinical practice and basic research in Korea.

• Journal of Korean Medicine for Obesity Research
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• v.4 no.1
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• pp.201-211
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• 2004

The treatment of obesity is increasingly becoming important to effective medical treatment, especially in case involving a degradation of the lower joints. A recent case placed two osteoarthritic obese patients who underwent arthroscopic surgery in a regiment of herbal diet. Alter 3-5 months of receiving this oriental treatment, the patients not only lost weight, but also showed significant reduction of joint inflammation and pain. It is true that obese patients with lower limb or osteoarthritis who have undergone normal obesity treatment regularly for 5 years or more will find the treatment becomes less effective over times. However, for patients suffering from lower limb pain or osteoarthristis, oriental obesity treatment, on the whole was effective in decreasing five key areas(5D). For this reason, it is necessary for oriental medicine to be given further study and consideration as an effective treatment of obesity.

• Journal of Korean Medicine for Obesity Research
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• v.5 no.1
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• pp.133-140
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• 2005

The prevalence of obesity at all ages in increasing epidemically worldwide. There were many study of an indirect method on fat mass measurement in obesity, but were few study to determine the possible relationships between local fat deposition and health-related fitness parameters in overweight and obesity. We has reviewed on the somatotype characteristics, ideal posture and biomechanics, and adipose tissue of connective tissue, myofacia continuity. We consider that these unique 'whole systems' view is of vital importance to understanding the role of adipose tissue in musculoskeletal system and to application of body shape correction program.