• Journal of Korean Medicine for Obesity Research
• /
• v.12 no.2
• /
• pp.17-27
• /
• 2012

Objectives: This study was designed to confirm the ethnic and socioeconomic differences in the obesity of Uzbekistan. Methods: From 139 patients, visited Korean-Uzbekistan friendship hospital of Korean Medicine, gathered the information of the sex, height, weight, ethnic group, economic status, education level, self-desired weight, self-perception of weight status and experiences of weight reduction. Also patients completed the 10 questions about the association between obesity and disease. Results: Koreans in Uzbekistan showed a significant lower value of body mass index (BMI) and a significant higher understanding between obesity and disease than other ethics. Socioeconomic differences in the obesity were not confirmed. People of Uzbekistan showed a little experience of weight reduction. Conclusions: Koreans in Uzbekistan have a different prevalence and perception of the obesity with other ethnics. Researches about the relationship between obesity and metabolic factors, and prevention programs for obesity and metabolic syndrome are needed for the public health of Uzbekistan.

• Journal of Korean Medicine for Obesity Research
• /
• v.20 no.2
• /
• pp.178-192
• /
• 2020

Objectives: The present study aimed to compare the impacts of cognitive behavioral therapy (CBT) and behavioral treatment (BT) on weight loss and psychological outcomes among patients with three different subtypes of obesity: simple obesity, obesity with binge eating disorder, and obesity with depression. Methods: Embase, PubMed, the Cochrane Central Register of Controlled Trials, Research Information Sharing Service, and Korean Studies Information Service System were systematically searched for randomized controlled trials conducted on or before May 2020, that used CBT to treat obesity. Methodological quality was assessed using Cochrane's risk of bias tool 2 and publication bias was evaluated through the funnel plot using the trim and fill method, Egger's test, and Begg and Mazumdar rank correlation test. A meta-analysis was conducted using a random-effects model and the standardized mean difference with 95% confidence interval (CI) was used to determine effect size. Results: Twenty-one randomized controlled trials with a total of 22 intervention arms and 2,590 patients were included. Our study results revealed that the effects of CBT, compared with BT, on weight loss distinctly differed across all patient subgroups. In the simple obesity group, CBT was more effective than BT (Hedges' g=0.138, CI=0.012~0.264); however, in the obesity with binge eating disorder group, BT was more effective than CBT (Hedges' g=-0.228, CI=-0.418~-0.038); in the obesity with depression group, the effect of CBT was not statistically different from that of BT (Hedges' g=0.276, CI=-0.307~0.859). Further studies with larger sample sizes are required to confirm the outcomes observed in this study. Conclusions: Our results indicated that the effects of CBT on obesity treatment vary based on patient subtype. Therefore, our findings suggest that CBT or BT should be selectively recommended as a treatment strategy for different obesity subtypes.

• The Korean Journal of Physiology and Pharmacology
• /
• v.21 no.6
• /
• pp.567-577
• /
• 2017

Obesity is known to induce inhibition of glucose uptake, reduction of lipid metabolism, and progressive loss of skeletal muscle function, which are all associated with mitochondrial dysfunction in skeletal muscle. Mitochondria are dynamic organelles that regulate cellular metabolism and bioenergetics, including ATP production via oxidative phosphorylation. Due to these critical roles of mitochondria, mitochondrial dysfunction results in various diseases such as obesity and type 2 diabetes. Obesity is associated with impairment of mitochondrial function (e.g., decrease in $O_2$ respiration and increase in oxidative stress) in skeletal muscle. The balance between mitochondrial fusion and fission is critical to maintain mitochondrial homeostasis in skeletal muscle. Obesity impairs mitochondrial dynamics, leading to an unbalance between fusion and fission by favorably shifting fission or reducing fusion proteins. Mitophagy is the catabolic process of damaged or unnecessary mitochondria. Obesity reduces mitochondrial biogenesis in skeletal muscle and increases accumulation of dysfunctional cellular organelles, suggesting that mitophagy does not work properly in obesity. Mitochondrial dysfunction and oxidative stress are reported to trigger apoptosis, and mitochondrial apoptosis is induced by obesity in skeletal muscle. It is well known that exercise is the most effective intervention to protect against obesity. Although the cellular and molecular mechanisms by which exercise protects against obesity-induced mitochondrial dysfunction in skeletal muscle are not clearly elucidated, exercise training attenuates mitochondrial dysfunction, allows mitochondria to maintain the balance between mitochondrial dynamics and mitophagy, and reduces apoptotic signaling in obese skeletal muscle.

• Journal of Korean Medicine for Obesity Research
• /
• v.3 no.1
• /
• pp.75-84
• /
• 2003

Objective : In Western medicine, the cause of obesity include overeating, lack of exercise, genetic factor, endocrinal impediment and psychological factor. Since the society becomes more complexed and the tensions among social members gets intensified, psychological factor getting more important. In Oriental medicine, Seven Emotion(七情, in oriental medical term) as an emotional stressor was thought to be a factor of obesity. Therefore the purpose of this study is to examine the relationship between Seven Emotion and obesity in detail. Methods : overview the stress with the view of Oriental medicine and research the relationship between Seven Emotion as an emotional stressor and obesity. Results : 1. Seven Emotion can be understood as an emotional stress in Western medicine. If Seven Emotion is excessive, its extreme mental stimulation causes physical illness. 2. Having influence upon the function of internal organs, excessive Seven Emotion causes obesity. Since it hinders normal flow of Gangi(肝氣), Seven Emotion disturbs healthy function of Bi-Wi(脾胃) and normal fluctuation of Qi. Consequently, obesity is resulted from the accumulation of fat since normal metabolism of body is disrupted. 3. In Seven Emotion-Anger(怒), Joy(喜), Anxiety(憂), Thought(思), Sorrow(悲), Fear(恐), Surprise(驚)-give rise to Gan-bi-bul-wha(肝脾不和), Sim-hi-yang-huh(心脾兩虛), Bi-qi-huh(碑氣虛), Dam-sup-jeo-po(痰濕沮胞) and Wi-wha-sang-youm(胃火上炎) in type of symptom in obesity and therefore, cause obesity.

• Journal of Korean Medicine for Obesity Research
• /
• v.11 no.2
• /
• pp.41-68
• /
• 2011

Objectives: After organizing segmentations related to obesity from classics and each studies, we would like to examine the value of wild ginseng, bovis calculus, ursi fel and moschus as a obesity medicine. Methods: We found out 4 drugs which are wild ginseng, bovis calculus, ursi fel and moschus from the classics, such as "Shin-Nong-Bon-Cho-Kyung", "Myoung-Eui-Byul-Lok", "Bon-Cho-Gang-Mok", "Bon-Cho-Jong-Shin", "Bon-Cho-Bi-Yo", "Bon-Cho-Gu-Jin" and "Deuk-Bae-Bon-Cho", we searched websites such as RISS, Korean traditional knowledge portal, the society of Korean medicine for obesity research, Korean pharmacopuncture institute, the Korean academy of oriental rehabilitation medicine and Korean acupuncture & moxibustion society as well. Results: 1. We couldn't find the contents related to the efficacy of improving obesity through wild ginseng, bovis calculus, ursi fel and moschus from the classics. 2. Wild ginseng had a study dealing with the efficacy of anticancer, obesity, toxicity, immunity, sulfation, diabetes, plasma proteins, depression, hypertension, endometriosis and hair loss. Especially among 6 studies related to obesity, apart from the study that treated extract of wild ginseng directly to the cell or oral administration to the animals, also have studies that had an efficacy of improving obesity through injecting pharmacopuncture to acupuncture point and vein, etc. 3. Bovis calculus had a study about efficacy related to arthritis, liver, inflammation of cornea, obesity, anticancer, immunity, antacid, heart, lumbar pain, hypertension, toxicity, a digestive organ and sasang constitution, especially in case of obesity, had each studies about oral administration of complex prescription and about cell unit experiment of pharmacopuncture. 4. Ursi fel had a study about efficacy related to liver, arthritis, inflammation of cornea, immunity, obesity, anticancer, antacid, lumbar pain, digestive organ, toxicity, cell protection, skin ailment, etc. Especially in case of obesity, had each studies about oral administration of animal experiment and about cell unit experiment of pharmacopuncture. 5. Moschus had a study about efficacy related to liver, the central nervous system, arthritis, inflammation of cornea, immunity, obesity, anticancer, hypertension, heart, lumbar pain, etc. Especially in case of obesity, had one study about oral administration of complex prescription. Conclusion: Through the result of probability as a obesity medicine of wild ginseng, bovis calculus, ursi fel and moschus, we could identify the possibility of each drug as a obesity medicine. Also in the future, it is considered that studies about one or complex prescription and pharmacopuncture as a obesity medicine will be needed.

• Nutritional Sciences
• /
• v.5 no.3
• /
• pp.129-133
• /
• 2002

Obesity is a major public health problem in western countries. Genetic and environmental factors, separately or in combination are major determinants of fat mass. Both central effectors (primarily hypothalamus) and peripheral tissues (such as adipose tissue) are implicated in the pathogenesis of obesity. A significant number of studies have documented potential contribution of adipose tissue -via its newly discovered secretory function- to the pathogenesis of obesity and co-morbid conditions including cardiovascular disease, diabetes and hypertension. Applications of analytical techniques such as genomics and proteomics have enabled better understanding of biological sciences in general and have only being applied recently to nutritional sciences including obesity research. Here, we review the recent progress in adipose tissue functional genomics and proteomics, and the importance of these studies in energy metabolism and obesity research.

• Child Health Nursing Research
• /
• v.25 no.1
• /
• pp.28-37
• /
• 2019

Purpose: This study was conducted to examine factors associated with obesity among Korean adolescents. Methods: The participants were 436 Korean adolescents aged 12~18 years who took part in the seventh Korea National Health and Nutrition Examination Survey (2016). The data were analyzed by descriptive statistics, the $x^2$ test, one-way analysis of variance, and multinomial logistic regression using complex sample analysis. Results: Among the participants, 9.7% were classified as being obese, and 11.9% as being overweight. Several health parameters, including systolic blood pressure, diastolic blood pressure, waist circumference, and triglyceride, fasting blood sugar, and alanine aminotransferase levels, varied according to obesity. Distorted perceptions of body shape showed a significant negative association with overweight, and carbohydrate intake was negatively associated with obesity. Conclusion: These findings indicate that obesity in Korean adolescents was associated with lifestyle and health parameters. Therefore, intervention programs for obese or overweight adolescents should focus on preventing them from developing health problems.

• Child Health Nursing Research
• /
• v.11 no.2
• /
• pp.240-245
• /
• 2005

The problem of childhood obesity is accelerating throughout the world. Korea is no longer an exception to this problem. The following topics are discussed in this review article: 1) the linkage between childhood obesity and adult obesity, which is often associated with metabolic diseases such as type2 diabetes, hypertension, cardiovascular diseases, and certain cancers; 2) characteristics of childhood obesity; 3) measurement of obesity and its unique problem; 4) recent trends in interventions for childhood obesity. Lastly, the author points out that nurses are best suited for carrying out interventions to prevent obesity in childhood. As childhood obesity is a risk factor for persistence of obesity into adulthood, the need to consider the priority of prevention of obesity during childhood is emphasized in this review.

• The Journal of Pediatrics of Korean Medicine
• /
• v.24 no.2
• /
• pp.31-39
• /
• 2010

Objectives The recent prevalence rate of obesity in children is increasing, but so far the majority of ongoing research is focused on obesity in adults. Even comparison studies between obesity in adults and in children are insufficient at this stage. Thus, our research will investigate the characteristics of obesity in children based on the comparison with adults. Methods The blood levels including glucose, cholesterol, AST, ALT of obese children and obese adults were compared and analyzed. Results From comparison studies, the levels of glucose, cholesterol, ALT in adults were higher than in children. In order to take account the age differences, only the rate of abnormal levels based on the reference range were compared. As a result, the abnormal rate in blood cholesterol level was higher in children. Conclusions Childhood obesity may develop complications at early age and has high potential risk to result in adult obesity as well. Therefore, child obesity needs to be treated with more caution and careful attention.

• Journal of Korean Medicine for Obesity Research
• /
• v.9 no.1
• /
• pp.45-51
• /
• 2009

Objectives The purpose of this study was to investigate the effect of oriental treatment on pediatric overweight and obesity. Methods From the December 2006 to the May 2008, 19 children were treated of obesity control in J Korean Hospital, electrolipolysis, auricular acupuncture was done 2 times per week for 4 weeks with the consulting of diet and exercise. Nine children were treated for 9 weeks. We checked the change of weight at treatment time and the body composition measured by bioelectrical impedance analysis(BIA) per 2 weeks. Results After 4 weeks treatment, the weight loss was 2.67${\pm}$1.75kg. And after 9 weeks treatment, the weight loss of 9 children was 5.91${\pm}$2.73kg. Total fat mass measured by BIA significantly decreased 2.38${\pm}$1.19kg after 4 weeks. BMI and the weight loss of children were significantly correlated. After 4 weeks treatment the BMI significantly decreased 1.43${\pm}$0.89kg/m$^2$. After 8 weeks treatment the BMI of 9 children significantly decreased 3.31${\pm}$1.47kg/m$^2$. Conclusions The pediatric obesity could be effective treated by herdal medicine and electroacupuncture.