• Journal of the Korean Society of Food Science and Nutrition
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• v.28 no.2
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• pp.464-470
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• 1999

The purpose of this study was to investigate the effect of zinc intake on immune responses in high fat diet induced obese rats. The immune status was assessed by the measurements of immunoglobulins (IgG, A, and M) production by SRBC(sheep red blood cell) with mitogen in vivo. The delayed type hypersensitivity(DTH) response was also measured as an index of cell mediated immunity. The re sults are summarized as follows : 1) There were no significant differences in the feed intake, weight gain and feed efficiency ratio of obese rats by the different dietary zinc levels. 2) White blood cell (WBC) counts were significantly affected as the dietary zinc levels decreased. The capacity of Ig M production in obese rats was significantly higher in normal zinc group than that of low and high zinc group. Cell mediated immune response evaluated by means of DTH testing has also been found to be highly impaired by zinc deficiency and overload. From these observations, it was suggested that adequate levels of zinc may promote the immune function of obese individuals. The relationship and its functional role of the zinc in obesity remains to be further studied.

• Journal of Korean Medicine Rehabilitation
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• v.18 no.3
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• pp.51-65
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• 2008

Objectives : In order to investigate the effects of Soongijeseub-bang(Shunqichushi-fang)(here in after referred to SJB) on the obese gene and obese inhibitory, on C57BL/6 mice were induced by high fat diet. Methods : C57BL/6 mice were divided into three groups(normal, high fat diet with control, high fat diet with SJB extract) and fed for 15 weeks. And observed that, body weight change, final increase of body weight, the weight change of the adipocytes, the level change of ALT, AST, creatinine, total cholesterol, LDL-cholesterol, HDL-cholesterol, triglyceride, NEFA, glucose, the expression of ${\beta}3AR$, leptin, and $TNF-{\alpha}$ gene in primary adipocytes and adipocytes tissue. Results : The following results were obtained in this study. 1. SJB 500 mg/kg extract group showed considerable decrease in weight, the final increase of weight and the amount of adipocyte in weight. 2. All experimental group showed that the amount of ALT, AST, total cholesterol, LDL-cholesterol, triglyceride and NEFA were decreased considerably. SJB 500 mg/kg extract group showed the amount of HDL-cholesterol and leptin were increased considerably. 3. All experimental group showed that the revelation of ${\beta}3AR$ in primary adipose cell and 3T3-L1 cell were increased considerably, and that the revelation of leptin in primary adipose cell and 3T3-L1 cell were decreased considerably. SJB $100{\mu}{\ell}/m{\ell}$ extract group showed that the revelation of $TNF-{\alpha}$ were decreased considerably. 4. SJB 500 mg/kg extract group showed that the size of adipocyte in adipocytes tissue were decreased. 5. All experimental group showed that the adipose vacuoles in liver tissue were decreased considerably. Conclusions : Comparison of the results for this study showed that SJB is effective on obesity care and has obese-inhibitory effects in obese mouse induced by high fat diet. So it is respected that the clinical application of SJB can help the treatment of obesity.

• Preventive Nutrition and Food Science
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• v.14 no.4
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• pp.290-297
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• 2009

This study was carried out to investigate the dietary effects of chitosan mixture (CM), an herbal medicine mixture with Sukjihwang (HS), and CM containing HS (CHS) on obesity in an induced obese model of rats fed high-fat only (HF), in which supplemented diets of 5% CM (HCM), 5% HS (HHS), or 2.5% CM-2.5% HS (HCH) was tested for 6 weeks. Body weight gains, obesity indexes, and body fat contents in the experimental groups (HCM, HHS, HCH) were decreased compared with HF group. The levels of serum triglyceride, total lipid, total cholesterol and LDL-cholesterol in the experimental groups were markedly decreased, however HDL-cholesterol levels in the experimental groups were slightly increased compared with HF group. In addition, although serum ALT and AST activity, and relative organ weights were lower than those of HF group, serum albumin contents were not significantly different in all experimental groups including the normal control group (NC). In conclusion, there are improved effects on obesity in the obese model of animals with all experimental diets supplementations, and the improvement degrees on obesity depend on the content and compositions of the herbal medicine mixture. Further study is needed on the anti-obesity mechanism of these diets.

• International Journal of Contents
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• v.13 no.3
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• pp.49-58
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• 2017

This is a descriptive research study that classified Korean adults with obesity into those with Metabolically Healthy Obesity and those with Metabolically Unhealthy Obesity based on the data from the fifth and sixth South Korea's National Health and Nutrition Examination Surveys, designed due to the development of information and communication technology, to examine the impacts of obese adults' health behavior factors and mental health factors on their metabolic state. With respect to data analysis, the collected data were analyzed by complex sample statistics. The results of this study can be summarized as follows: Men who were smoking at the time of the survey had a 1.29 times higher probability of inclusion in the MUO group than in the MHO group. Women who had a high stress cognition rate had a 1.02 times higher probability of inclusion in the MUO group than in the MHO group. This study is significant as it provides the basic data for establishing strategies of nursing intervention for the promotion of obese adults' health, and it suggests that it is necessary to develop a program for the promotion of obese adults' health based on these results.

• Journal of Korean Medicine for Obesity Research
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• v.5 no.1
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• pp.67-73
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• 2005

Objectives : This study is to examine associations between diet and eating behavior with body mass index(BMI) in Korean office ladies. Methods: From OCT 2004 to OCT 2005, we collected obese office ladies who visited to the oriental obesity clinic and control group who were matched by age, occupation, working hours. Weight and height were self-reported. Subjects were divided to obese and non obese group by body mass index(BMI). Diet, eating behavior were determined from 21-item self-administered questionnaire. Independent paired t test was used for analyzing associations between diet, eating behavior and body mass index(BMI) Results: There were 141 participants in obese group and 50 participants in control group. Eating fast, skipping breakfast, night eating habit(p<.001), eating fatty food, drinking alcohol were highly positively associated with body mass index(BMI) values. There was no conclusive evidence that diet except fatty food were related to obesity. Conclusions: Eating behaviors are strongly related in obesity but associations between diet and obesity are not clear.

• Journal of the Korean Society of School Health
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• v.11 no.1
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• pp.99-110
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• 1998

The purpose of this study is to investigate the effect of obese school children's life style habits in order to help school nurse in controlling and preventing the obesity by health education The survey group is extracted from the students of two elementary schools located in Seongnam city Out of 280 children randomly sampled, 102 children were evaluated to be obese and 178 ones to be normal by the standard of the 1985 Korea Pediatric Association Height and Weight Standard Chart The obese children group was compared with the normal one. For this purpose, the surveyors designed a self questionnaire to obtain the description of general background, exercise including play behavior, eating behavior, and family environment of the sampled children. The results are as follows The number of the obese children who took extracurricular physical exercises was significantly (p<0.05) more than that of the normal ones The significantly (p<0.05) more obese children went without a meal to control their weight than the normal ones. In relation to the degree of obesity, the children with the high degree of obesity watched the television significantly (p<0.05) longer than the ones with the mild and the moderate degree of obesity In gender relations, the obese girls participate in outdoorplays and physical exercises significantly (p<0.05) longer and more regularly than the normal ones, while no significant difference was found between the male groups The obese boys had significantly (p<0.05) their mothers occupying in a vocation. Combining television watching habit and mother's vocation of the obese boy, the obesity is resulted from complicated situation It can not be due to the simple absence of the mother, but rather due to the absence of a person responsible for controlling snacking and television watching time of the child Looking at the results, it is necessary for both school and home to actively involve in guiding children and providing an environment to modify life style habits and prevent childhood obesity.

• Journal of Community Nutrition
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• v.4 no.1
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• pp.12-21
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• 2002

This study was conducted to investigate the dietary intake, anthropometric data, and association between two factors and main food sources contributing macronutrients for overweight and obese females. Subjects were 85 adult females (overweight : 28, obese 57) where mean age was 38.7y. The results are summarized as follows. Mean fat percent, BMI, obesity rate were 29.3, 23.9 and 15.1%, respectively for overweight women and 32.7, 28.3, 36.4%, respectively for obese women. There were significant differences for most of the anthropometric data between groups. Fat percent for all subjects was significantly correlated with weight, waist circumference, hip circumference, mid arm circumference or skinfold thickness for the triceps, subscapular and suprailiac (p < 0.001). The parameter which showed the highest correlation coefficient (r=0.6156) with fat Percentage was the waist to hip ratio. Any significant differences were not found in dietary intake of nutrients or in diet composition between groups. The mean energy intake was 2090.1kcal (104% of RDA) for overweight women and 2113.0kcal (106% of RDA) for obese women. PFC ratio for overweight was 17 : 24 : 59 and 18 : 23 : 58 for obese subjects, which can be regarded as higher fat and lower carbohydrate percentages compared to recommended PFC ratio (15 20 65) .4) Fat intake was positively correlated (r : 0.2301, p < 0.05) with the triceps skinfold thickness, protein intake was also positively correlated with waist circumference (r=0.2668, p < 0.05) or fat weight(r: 0.2406, p < 0.05) .5) The main food items that contributed to energy intake for overweight or obese subjects were similar (rice, pork, bread, grapes, barley) except com oil in overweight or instant noodle for obese group. The subjects in this study were taking less energy from rice and more energy from pork and bread than women from 98 National Health and Nutrition Survey. Because there were no significant differences of dietary data between overweight and obese group, further investigation considering basal metabolic rate or activity would be needed.

• Herbal Formula Science
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• v.21 no.2
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• pp.44-52
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• 2013

Objectives : Samhwangsasim-tang (SST), Hwangryeonhaedok-tang (HHT), Ukgan-san (UGS), Onjunghwadam-hwan (OHH) and Samul-tang (SMT) have been used for the treatment of various diseases. This study was performed to compare the anti-obesity effects of 5 herbal formulas in high fat diet-(HFD) induced obese mice. Methods : The mice were randomly divided into seven groups that were fed a normal diet (ND), a HFD, a HFD plus SST (HFD + SST), a HFD plus HHT (HFD + HHT), a HFD plus UGS (HFD + UGS), a HFD plus OHH (HFD + OHH), or HFD plus SMT (HFD + SMT) at 300 mg/kg/day for 7 weeks. All groups were assayed for body weights, food efficiency ratio (FER), final liver and fat weight and blood biochemical parameters. Results : The increased body weights, food efficiency ratio (FER), and serum total triglyceride were decreased in HFD + OHH group relative to the same measurements in HFD group. Furthermore, the HFD + SST group significantly reduced FER, liver and abdominal subcutaneous fat weight gains, and serum total triglyceride, whereas HDL-cholesterol level was increased compared to HFD group. Conclusions : These results suggested that HFD + OHH and HFD + SST exert anti-obesity effects in HFD-induced obese mice.

• Journal of Korea Association of Health Promotion
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• v.4 no.1
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• pp.95-103
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• 2006

Purpose: With remarkable increase in the prevalence of childhood obesity, nonalcoholic fatty liver disease increased, The aim of this study is to evaluate the prevalence of the increase liver enzymes, lipid levels and fasting blood glucose level in normal and obese children. Methods: A total of 2206 elementary students were grouped according to obesity index; normal group and obesity group(mild, moderate, severe). Aspartate aminotransferase(AST, SGOT) and alanine aminotrausferase(ALT, SGPT) were measured with tota1 cholesterol, triglyceride and fasting blood glucose. Results: Compared with the 2.7% of ALT > 50 IU/L in normal group, obese groups showed significantly higher prevalence; 6.7% in mild obesity group, 11.8% in moderate group and 15.0% in severe group. The prevalence of hypertriglyceremia was 12,4% in normal weight group, which is significantly lower than obesity group(mild obesity group 24.8%, moderate and severe 32.1% each). Conclusion: The prevalence of nonalcoholic fatty liver increased along with severity of obesity. Of Nutritional assessment, intervention, and preferably prevention are necessary for health promotion elementary students.

• Korean Journal of Community Nutrition
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• v.12 no.1
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• pp.40-49
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• 2007

This study was done to investigate the health-related habits, dietary intakes and serum lipid levels in overweight and obese women by body mass index(BMI). Subjects were 137 pre-menopausal women aged 19 to 49 years. They were divided by 3 groups, overweight($23{\leqq}BMI<25$), obese($25{\leqq}BMI<30$) and morbidly obese($BMI{\geq}30$) according to their BMI. Body composition was determined by bioelectrical impedance analysis(BIA) method. Dietary intakes were examined by 3-day record method and nutrient intakes were analyzed by the Computer Aided Nutritional analysis program for professionals(CAN-pro 3.1). Serum lipid levels were measured using automatic biochemical analyzer(Selectra E). The average age, height weight and BMI of subjects were 31.7 years old, 159.3cm, 69.4kg, and $27.4kg/m^2$, respectively. Their average consumption of energy were 1712kca1 and 86.4% of estimated energy requirement(EER). Their mom ratio of carbohydrate:protein:fat was 55.2:14.6:30.2. Particularly, the fat consumption of subjects tended to be elevated with increasing BMI. There was no significant difference in nutrient intakes among 3 groups. But the mom intakes of Ca, Fe, vitamin C and Na of all the subjects were 70.1%, 81.2%, 75.7% of recommended intake(RI) and 258.9% of adequate intake(AI), respectively, The intakes of vegetables and seaweeds were significantly higher in morbidly obese group while the intake of fruits was higher in overweight group compared to the other groups. Serum lipid analysis showed that there were no significant differences in the levels of total cholesterol, triglyceride and LDL-cholesterol among the groups. But the serum HDL-cholesterol level of the overweight group was significantly higher than that of the other groups. LDL-/HDL-cholesterol ratio and AI index were significantly higher in the morbidly obese group compared to the other groups. In addition, The systolic blood pressure of morbidly obese group was significantly higher compared to the other groups. Overall data suggest that morbidly obese women have to more concern about reducing systolic blood pressure and nm lipid levels by decreasing their fat consumption and salt intakes as well as loosing body fat. In addition, all the subjects participated in this study have to be careful about their meals and health-related behaviors in order to prevent obesity-related chronic diseases.