• 한국식품영양과학회지
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• 제26권5호
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• pp.892-900
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• 1997

This study was carried out to investigate the clinical characteristics of 78 diabetics by body fat distribution pattern. It was based on the survey of nutritional status, anthropometric measurements and serum components of the patients. The results were as follows: the average ages of male and female subjects were 57.1, and that of female subjects was 58.9, respectively. The average diabetic durations of male and female subjects were 4.8 and 5.9 years, respectively. In male, the ratio of upper body obese subject was 62.5% and the lower body obese subjects was 37.5%, while those of female were 69.4% and 30.6%, respectively. In nutrient intake state, there was no significant difference between male and female subjects, but calory intake of upper body obese subjects was difference between male and female subjects, but calory intake of upper body obese subjects was tend to be higher in both male and female subjects. among the three major nutrients/calory ratio, protein/calory ratio was significantly lower in the male upper body obese subjects than in the male lower body obese subjects. Since weight, circumference of arm and waist, waist hip ratio(WHR) of both male and female subjects, body muscle mass(BMM) of male subjects and body mass index (BMI) of female subjects were significantly higher in upper body obese group, upper body obese subjects represented ore fat than lower body obese subjects. In male subjects, hemoglobin(Hb), A/G of upper body obese subjects were lower than the standard value, but there was no significant difference in the serum components between two subjects. In female subjects, Hb and A/G of lower body obese subjects were lower than those of the normal subjects, but Hb and Ht of upper body obese subjects were significantly higher than those of the lower body obese subjects.

• 대한지역사회영양학회지
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• 제15권5호
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• pp.694-703
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• 2010

Recent studies have reported that a subset of obese individuals who were metabolically healthy but obese had more favorable clinical outcomes than obese subjects with metabolic disturbances. The purpose of this study was to evaluate the distribution and agreement of obesity subtypes according to body mass index (BMI) and metabolic syndrome (MS). Furthermore, we examined the differences of nutrient intake among the groups. Data was analyzed for 1,095 female subjects older than 40 years using Korean National Health and Nutrition Survey in 2008. The degree of obesity was classified by two methods, using BMI (obese ${\geq}\;25\;kg/m^2$, not obese < $25\;kg/m^2$) and MS (meet ${\geq}\;3$ criteria among 5 index: waist circumference, triglyceride, glucose, HDL-cholesterol and blood pressure). Subjects were divided into 4 groups according to $2{\times}2$ cross table: non-obese without MS, non-obese with MS, obese without MS and obese with MS. Nutrient intakes were compared among 4 groups. The results showed that the proportions of non-obese without MS, non-obese with MS, obese without MS and obese with MS were 47.6%, 13.6%, 16.6%, and 22.2% of total subjects, respectively. The agreement (kappa value) of two methods was 0.354 (fair) in total subjects, 0.365 (fair) in 40-60 year old subjects and 0.304 (fair) in ${\geq}\;61$ year old subjects. In ${\geq}\;61$ years old subjects, intakes of percentage energy from carbohydrate, percentage of energy from fat, calcium, phosphorous, sodium, vitamin A, carotene, thiamine, riboflavin and niacin were significantly different among the groups. In contrast, the subjects of 40-60 years old, no differences in nutrient intakes were observed. In conclusion, there were differences in nutrient intakes among the groups subdivided by obesity and MS, especially in elderly female subjects. Individualized dietary guideline for subtype of obesity will be needed to treat metabolic disturbance of obesity.

• 약학회지
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• 제44권5호
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• pp.391-398
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• 2000

Leptin, the product of the ob gene, is a small peptide molecule synthesized by white adipocytes with an important role in the regulation of body fat and food intake. Based on the evidence that synthesis of leptin is regulated by female sex hormone, estrogen, this present study was investigated whether sex hormone precursor DHEA, can regulate obese gene expression in lean and genetically obese (ob/ob) mice. Antiobesity activity of DHEA was evaluated by determining body weight, food consumption, epididymal fat weight and serum levels of cholesterol and triglyceride in ICR, C57BL/6J, and ob/ob mice. The treatment of C57BL/6J lean and obese mice with a diet containing 0.3% and 0.6% DHEA resulted in lowered rates of weight gain in comparison to non-treated mice, although much greater response was found in the obese mice. All other concentrations of DHEA (0.015%, 0.06%, 0.15%, 0.3%) except the highest one(0.6%) showed no significant effects on weight gain in ICR mice. Food consumption was significantly decreased in all mice treated with 0.6% DHEA, whereas it was not decreased in ICR mice at lower concentrations than 0.6% DHEA. DHEA decreased significantly epididymal adipose tissue weight and serum triglyceride levels dose dependently in lean and obese mice. However serum cholesterol levels were decreased at lower concentrations than 0.15% DHEA and increased at concentrations of 0.3% and 0.6% DHEA in lean and obese mice. These increases in serum cholestrol levels at high concentrations of DHEA might result from the fact that DHEA has a cholesterol moiety thereby interfered the assay system. As an approach to elucidate the mechanism for antiobesity activity of DHEA, we examined mRNA levels of obese gene in the adipocyte and obese gene product (leptin) in the serum. The results showed that DHEA did not affect obese gene expression in ICR and C57BL/6J mice. Therefore, we concluded that antiobesity activity of DHEA was not modulated by obese gene expression.

• Journal of Nutrition and Health
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• 제57권1호
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• pp.65-74
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• 2024

Purpose: Sodium is essentially required for homeostasis and physiological functions, but excessive sodium consumption increases the risk of obesity and other chronic disorders. Korean studies on the sodium-obesity relationship are limited, and thus, this study was undertaken to determine the nature of the relationship between sodium intake and obesity in Korean adults. Methods: Forty-two participants were divided into 2 groups according to body mass index (BMI, non-obese BMI < 25 kg/m², obese BMI ≥ 25 kg/m²). Dietary intakes and eating habits were analyzed using 3-day food records and a food frequency questionnaire. Anthropometric data were obtained from bioimpedance results, and fasting glucose and lipid levels were measured. Results: Mean weight, BMI, waist and hip circumferences, and body fat mass were greater in the obese group than in the non-obese group for men and women. Skeletal muscle mass and body fat mass were higher in obese women than in non-obese women. Biochemical data were no different in these two subgroups except triglycerides (TGs), which were higher in obese women. Nutrient intakes were not significantly different in obese and non-obese groups. However, obese men consumed excessive sodium, while obese women consumed slightly more than non-obese women. Obese men preferred salty foods and tended to overeat. Positive correlations were found between sodium intake and weight in men and percent body fat mass (PBFM) in women. Correlation analysis (adjusted for energy intake) of the relation between sodium intake and obesity-related factors showed sodium intake was positively correlated with PBFM and TG in women. Conclusion: This anthropometric and biochemical data analysis emphasizes the need for awareness and interventions to mitigate the health risks of elevated sodium consumption. Our findings should aid future studies on the relationship between sodium and obesity and contribute to preventing and managing this metabolic condition.

• 대한가정학회지
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• 제40권3호
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• pp.155-164
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• 2002

This study was conducted to investigate the differences in environmental and psychological factors in children with obesity and to offer useful information for obesity treatment and prevention. 123 children of 5-6th grade in elementary school and their mothers were included in this study and divided into either the obese group and normal group(obese group: 61, normal group: 62) according to the Weight-Length Index(WLI). Results showed that between the two groups there no significant differences in family income, mother's occupation status, educational level, and anthropometric measurement. Nutritional knowledge in the obese group was significantly higher than that of the normal group(p<0.05). The mothers of children with obesity had a higher level of nutritional knowledge than the mothers of normal children(p<0.05). There were no significant differences in food behavior between the obese and normal groups. There were no significant differences in maternal child-rearing practices and in maternal attitude on flood behavior of children. Considering psychological factors ; 72.1% of the children with obesity appraised their body image as obese(p<0.05), and 54.1% of the mothers in obese group perceived their child's body shape as obese(p<0.05). The level of self-esteem were not significantly different when compared between the obese and normal groups. From these results, it was suggested that effective measures for obesity treatment and prevention should include nutritional monitoring, and such efforts need to be maintained in order to help the obese children and their mothers.

• Journal of Community Nutrition
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• 제8권2호
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• pp.69-75
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• 2006

Adipose tissue has now been recognized as a rich source of metabolically active molecules that include leptin and angiotensinogen (AGT), the precursor of angiotensin II (Ang II). Both of which have been implicated in the pathogenesis of metabolic alteration and hypertension associated with obesity. In this study, we examined the relationship between body mass index (BMI), adipocyte size, leptin, Ang II secretion and mRNA expression in human adipose tissue obtained from female subjects. Leptin and Ang II were analyzed using specific radioimmunoassay kits following a 48hour tissue culture. Leptin and Ang II secretion varied from 1.4 - 72.1ng/g and 0.8 - 57.3pg/g of tissue respectively. These large individual variations limit significant correlation between BMI, leptin and Ang II secretion. Ang II secretion was significantly higher in the obese than the non-obese (p < 0.05) and positively correlated with BMI. However, no difference in leptin secretion between the obese and the non-obese was observed and leptin secretion showed negative correlation with BMI. No difference in leptin and AGT mRNA expression in adipose tissue between the obese and the non-obese was observed. Although several limitations of this study, we found increased Ang II secretion in obese patients compared with non-obese patients, and positive correlation between AGT and BMI. Observed difference in AGT expression between the obese and the non-obese in this study might be of importance in relation with obesity related hypertension. (J Community Nutrition 8(2): 69-75, 2006)

• 한국의류학회지
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• 제23권4호
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• pp.563-574
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• 1999

The purpose of this study was to provide basic information for obese boy's clothing construction that can reflect the characteristics of their bodies. The subjects for anthropometric measurements which were performed directly were obese boys of 9 to 11 year-old. To classify the somatotype and to analyze the characteristics of each somatotype 310 obese boys were examined. Data were analyzed by using multivariate method, By means of Ward the subjects were classified into 4 clusters according to the factor scores which were obtained from 6 factors providing the information of 54 items. 4 clusters were identified. 1) Type I was characterized by tall and obese type 2) Type II was characterized by short and small type 3) Type III was characterized by long and obese type of lower body. 4) Type IV was characterized by short and obese type.

• Journal of Nutrition and Health
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• 제28권11호
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• pp.1056-1064
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• 1995

This study was performed to investigate the difference between obese and non-obese male students. To conduct this study, anthropometric measurements, blood pressure, serum lipids and insulin concentration, and daily nutrients intake of obese and non-obese mal students were measured. The results are as follows : The anthrometric measurements of the two groups showed significant difference in weight (P<0.01), waist(P<0.001), hip(p<0.0001) and thigh (P<0.001) circumference, % of body fat(p<0.0001), kg of body fat(p<0.001) and LBM (lean body mass, p<0.0001). On the other hand, the blood pressure, serum lipids and insulin, and daily nutrients intake of the two groups showed no significant difference. The WHR showed positive correlation with weight, BMI, waist circumference, % of body fat and kg of body fat in obese group. It is also founded that waist circumference, % of body fat, kg of body fat, serum triglyceride, energy and carbohydrate intake in non-obese group showed positive correlation with WHR.

• Preventive Nutrition and Food Science
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• 제2권2호
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• pp.144-148
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• 1997

Insulin secretory response to various calcium concentrations was investigated in 10- to 12-week old male lean and obese Zucker rats using an in vitro pancreatic perfusion procedure. There was no significant difference in insulin secretion response to low, medium, and high calcium concentrations in the lean rat. However, the obese rat shows a characteristics of hypersecretion of insulin. The obese rat pancreas perfused with the low calcium concentration released as low insulin as the lean rat. When perfused with the medium calcium concentration, th obese rat pancreas released twice as much insulin as the lean rat. eh hypersecretory phenomenon was also seen in the obese rat pancreas perfused with the high calcium concentration during the first phase of erfusion period, but his phenomenon was gradually diminished during he second phase of perfusion period. These results indicate that there may be a selective insulin secretory response to the extracellular calcium in he obese Zucker rat pancreas.

• Nutritional Sciences
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• 제5권4호
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• pp.234-244
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• 2002

This study was conducted to compare the rates of hyperlipidemia, hypertension, high blood glucose, and liver dysfunction, between 64 obese children (24 boys and 11 girls who were moderately obese, and 21 boys and 8 girls who were severely obese) and 45 normal weight children (31 boys and 14 girls) from 13 elementary schools in Kangnung city. Among the boys with severe obesity, the levels of serum triglycerides and LDL-cholesterol (133.60 $\pm$ 49.99 mg/dl and 105.00 $\pm$ 41.12 mg/dl( respectively) were significantly higher compared to the normal Weight group (81.16 $\pm$ 23.59 mg/dl and 87.74 $\pm$ 32.095 mg/dl, respectively) of moderately obese group (102.30 $\pm$ 36.03 mg/dl, 89.99 $\pm$ 32.10 mg/이, respectively). In girls, only serum triglycerides were significantly higher in the severely obese group (154.30 $\pm$ 46.84 mg/dl), compared with the normal weight group (80.00 $\pm$ 25.31 mg/dl) or moderately obese group (106.40 $\pm$ 41.73 mg/dl). In boys, blood pressure in the severely obese group (systolic: 120.5 $\pm$ 9.74 mmHg; diastolic: 80.95 $\pm$ 10.44 mmHg) was significantly higher compared with the groups of normal weight or moderately obese children. The rate of hypertriglyceridemia was significantly different among normal weight, moderately obese, and severely obese boys (9.7%, 41.7%, and 76.2%, respectively). The proportion of boys who had an Atherogenic Index(AI) higher than 3 was found to be significantly higher in the severely obese group (28.6%), compared to 6.5% in the normal weight group and 4.1% in the moderately obese group. Among boys, a significantly higher rate of hypertension was found in the severely obese group, which showed high systolic blood pressure and high diastolic pressure (81.0% and 81.0%), compared with the normal weight group (16.1% and 22.6%) and moderately obese group (33.3% and 33.3%). In conclusion, the diagnosis and management of obese children needs to be tailored to gender and the degree of obesity. Furthermore, a systematic management program needs to be developed for early screening and detection of obesity in order to minimize the risk of hyperlipidemia and hypertension, especially in severely obese children.