To improve the storage method of Kimchi, optimum ripening Kimchi for an irradiation treatment(the time of around 0.3% in total acidity of Kimchi) was irradiated by doses of 1, 2, 3 kGy with Co-60 ${\gamma}-radiation$ and stored at $10^{\circ}C$. Total aerobic bacteria increased in the beginning of storage and then decrease slowly as the number of total lactic acid bacteria increased. Total lactic acid bacteria initially loaded by $10^8\;cells/ml$ in Kimchi shortly after irradiation reduced to $10^4-10^6\;cells/ml$ with 1-3 kGy doses and decreased gradually through the whole storage period. The initial load of yeast, $10^3\;cells/ml$, increased steadily during Kimchi storage and led to more than $10^4\;cells/ml$ after 30 days of storage. While it maintained tha the load in 2-3 kGy irradiated groups after 30 days of storage was less than that at the beginning of storage. pH, acidity and volatile acid in the nonirradiated group were 4.0, 0.7% and 0.06%, respectively at the 15th day after storage, but at the 30th day after storage, 2-3 kGy irradiated groups showed different values, 4.1, 0.58-0.63%, and 0.04-0.05%, respectively. The texture(firmness) of Kimchi reduced along with storage time, and 2 kGy irradiated group proved most favourable in its texture during storage. In the sensory evaluation of Kimchi, nonirradiated group was inedible after 15 days of storage, whereas 2-3 kGy irradiated groups could proling the storage-life of Kimchi over 2 times compared with the nonirradiated Kimchi, showing the good sensory quality even after 30 days of storage.
The purpose of this study was to evaluate the effect of different etching times on microtensile bond strength (${\mu}TBS$) to dentin both initial and after thermocycling with 3 different types of total-etching adhesives. Fifty four teeth were divided into 18 groups by etching times (5, 15, 25 sec), adhesives types (Scotchbond Multipurpose (SM), Single Bond (SB), One-Step (OS)) and number of thermocycling (0, 2,000 cycles). Flat dentin surfaces were prepared on mid-coronal dentin of extracted third molars. After exposed fresh dentin surfaces were polished with 600-grit SiC papers, each specimen was acid-etched with 35% phosphoric acid (5, 15, 25 sec) and bonded with 3 different types of total etching adhesives respectively. Then, hybrid composite Z-250 was built up. Half of them were not thermocycled (control group) and the ethers were subjected to 2,000 thermocycle (experimental group). They were sectioned occluso-gingivally into $1.0\;{\times}\;1.0\;mm^2$ composite-dentin beams and tested with universal testing machine at a crosshead speed of 1.0 mm/min. Within limited data of this study, the results were as follows 1. There was no statistically significant difference in ${\mu}TBS$ between the thermocycled and non-thermocycled groups, except for both SM and SB etched for 25 sec. 2. In thermocycled SM and SB groups, bond strength decreased by extended etching time. In total etching systems, adhesive durability for dentin could be affected by type of solvents in adhesive and etching time. Especially, extended etching time may cause deteriorate effects on bond strength when ethanol-based adhesive was used.
Oocyte donation program developed to reach the pregnancy in those patients suffering from premature ovarian failure or surgery induced menopause, particularly in their reproductive age. With technical advances and popularity of ART (assisted reproductive technology), the indication of oocyte donation program extended to low responders, and even to naturally menopaused patients that has led them quite successfully to getting in pregnancy. The purpose of this study was to evaluate which one is involved in the decline of fertility between the oocyte and uterine factor. One hundred five cycles of oocyte donation program were performed in 84 patients from Jan., 1993 to Dec., 1996. Oocytes were donated from healthy, young, fertile anonymous donors or relatives or infertile patients with supernumerary oocytes. The study population was divided into 3 groups according to the age of recipients. Group 1 was less than 35 years old, Group 2 was between 35 to 39 years old, and Group 3 was more than 39 years old. The results were as follows: The mean age of oocyte donor was $31.5{\pm}3.3$ (range; 25-36). The mean concentration of basal serum FSH and peak serum estradiol were not different among groups. The mean number of oocytes retrieved from donors, embryos transferred to recipients, and fertilization rate were not different among groups. The clinical pregnancy rate was 37.3% in Group 1, 31.6% in Group 2, and 31.6% in Group 3, respectively. The spontaneous abortion rate was 16.0% in Group 1, 16.7% in Group 2, and 16.7 in Group 3, respectively. The multiple pregnancy rate was 20.0% in Group 1, 16.7% in Group 2, 16,7% in Group 3, respectively, The implantation rate was 11.3% in Group 1, 10.3% in Group 2 and 10.0% in Group 3, respectively. All of the pregnancy outcomes were not different statistically among groups. In conclusion, endometrial receptivity does not seem to be impaired as age increases with transfer of good quality embryos and adequate endometrial preparation.
Bae, Young Ok;Hwang, Jun Soo;Kim, Sung Il;Lee, Joon Ha
Progress in Medical Physics
/
v.28
no.4
/
pp.156-163
/
2017
To verify the usefulness of a steam sterilizer equipped with an electronic Bowie-Dick test system, this study was carried out using two methods, utilizing both a steam sterilizer and an electronic Bowie-Dick tester. The first method is to confirm the error detection of the chemical Bowie-Dick test pack and the electronic Bowie-Dick tester in a malfunctioning sterilizer environment. For this purpose, the Bowie-Dick test program for the steam sterilizer was used to test three types of test packs commonly used in hospitals and the electronic Bowie-Dick tester by changing the set values of temperature, time, and vacuum frequency. The second is an experiment to check the sterilizer's normal operation with the electronic Bowie-Dick tester and the usefulness of grasping the cause of the malfunction. The results showed that the sterilization temperature was the same as that of the test pack at a temperature $1{\sim}6^{\circ}C$ lower than the reference temperature of $134^{\circ}C$. In the test with the sterilization exposure time as a variable, there was a normal discoloration at a time difference of 30~90 s. In the experiment using the number of vacuum cycles, the test was correct by performing the normal discoloration only at the normal condition of 3 times. The test results of 30 hospitals were 100 failure tests by a total of 291 Bowie-Dick tests. Of these, the failure factors related to an internal temperature that the chemical test packs could not detect were the greatest, and the four factors related to temperature, including the internal temperature, were found to be 71.18% of total malfunctions. In addition, the Bowie-Dick tester was provided within 30 min after the start of the Bowie-Dick test to confirm the performance of the sterilizer and the detailed cause. A steam sterilizer equipped with an electronic Bowie-Dick test system is used to manage individual sterilizers. In the current steam sterilizer with many temperature-related errors, it is possible to check the malfunction of the temperature difference that the test pack cannot detect, and the cause of error for the sterilizer is immediately detected after the test. The steam sterilizer equipped with the electronic Bowie-Dick test system assists with infection control with accurate sterilizer performance assurance.
This study was performed to compare the fatigue limit of stainless steel wires and Fiber-reinforced composites (FRC) under conditions of permitting physiologic tooth movement. and to evaluate the clinical value of FRCs which was used to reinforce the anchorage unit. The stainless steel wire groups were divided into round and rectangular wire groups. The FRC groups were divided into uni-directional and woven groups, with resin coating and without resin coating in the Proximal area After the number of cycles to failure of each of the 6 groups were measured within the $5{\times}10^5\;cycle$ fatigue limit simulating the orthodontic treatment period. the fatigue limit of each group was compared with each other The findings of this study were as follows. In stainless steel wires, the fatigue limit of rectangular wires were higher than that of round wires. But there was no statistically significant difference (p>0.05). In FRCs with resin coating and without resin coating in the interproximal area, the fatigue limit of uni-directional type was higher than that of the woven type (p<0.05). In uni-directional and woven type FRCs, the fatigue limit of FRC with resin coating in the interproximal area was higher thar that of FRC without resin coating (P<0.05) As the FRCs and stainless steel wires did not fracture until the $5{\times}10^5\;cycle$ fatigue limit which clinically is useful. it is sufficient to use FRC and stainless steel wire for reinforcing anchorage. When esthetics is important and the attachment of additional devices are necessary. it seems sufficient to use FRC as anchorage reinforcement.
Journal of the Computational Structural Engineering Institute of Korea
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v.33
no.1
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pp.9-16
/
2020
The objective of this study is to propose closed-form solutions to the free vibration response of single-degree-of-freedom (SDOF) systems, as part of fundamental research on dynamic systems with Coulomb friction. The motion of a dynamic system with Coulomb friction is described by a nonlinear differential equation, and, due to the variation in the sign of friction force term with the direction of motion, it is difficult to obtain the closed-form solution. To solve this problem, the nonlinear differential equation is directly computed by numerical integration, or an approximated solution is indirectly obtained using a linear differential equation wherein the damping effect due to Coulomb friction is replaced by an equivalent viscous damping term. However, these conventional methods do not provide a closed-form solution from a mathematical point of view. In this regard, closed-form solutions to the free vibration response of SDOF systems with Coulomb friction are derived herein by considering that the sign of the friction force term is reversed in each half-cycle of motion and by expanding it to the entire time history using the power series function. In addition, for a given initial condition, both the number of free vibration half-cycles and the response at the instant when free vibration motion stops are predicted under the condition that the motion of free vibration is stopped when the amplitude of the friction force is higher than that of the restoring force due to stiffness.
At the end of the 19th and in the early 20th centuries, Japan, Korea, and Manchuria, and areas throughout East Asia, suffered a number of cycles of growth and development, for which the railway was a very important development tool and was closely associated with national policy. East Asian affairs, especially at the time, seemed very important to the continent, and their influence on the advance of this remarkable era was especially prominent in Japan. In the midst of this period, the national railway may have evolved under national policy and railway policy and under a variety of organizations and persons of influence. In this paper, we have tried to find the similarities and differences among the three countries that built the East Asia Railway; we consider the characteristics of the East Asia Railway from the perspectives of these three countries. Comparing the characteristics of the three country's railways, first, Japan had the motives of continental expansion and modernization in its pursuit of the railway; in Korea, the railway played the role of a continental rail link; and in Manchuria there was a tendency to pursue direct domination of the railway. Second, the Japanese applied their railway model to Korea; the Korean railway may have been in operation, but it was an extension of the railway of Japan. The railway in Manchuria showed a similar pattern to that which can be found in the state of Asian domination of Europe ; Japan showed aspects of dominance over the railway because it had experience running a private railway.
In this study, the static and the fatigue tests were performed with high tension bolted joints, of which the surfaces were spread with inorganic zinc-primer after shot-blast, and milling surface, and steel-natural surface, difference of friction surface condition were examined by comparing the esults of tests. From the result of synthetical investigation of this study. it is proper that using the torque management method in order to introduce design axial force to blots, and the provision of specifications that initial axial forces must be 110% of design axial forces is proper. Decreasing ratio of axial forces to initial force is proportional to common lorgarithms of time progress, it converge constant value after 20 hours, and decreasing ratio is little related to the roughness of friction surface. Sliding coefficient of milling, spreading inorganic zinc-primer, just producting is great in order and sliding forces are dependent on the applied axial forces, but if the applied axial forces are great, sliding coefficient become small by a loss of roughness. So it is confirmed that relation between the applied axial forces and the sliding forces are not proportional linearly. From the result of estimation on fatigue strength, all specimens satisfy the specifications with B-grade and milling surface is lower than the others about 14% in fatigue strength because in milling surface lose the function of friction-types joints at lower number of cycles. From the result of eximination for the distribution area of compressive force, friction area near to inside bolt is wider in the direction of stress than near to outside. It is guessed that this situation occurs because outside bolts firstly change from the friction connection to the bearing connection.
This report documents a case in which the administration of an herbal product, an extract of the lacquer tree, Rhus verniciflua Stokes, as sequential and concurrent treatment with chemotherapy was associated with a long term survival and good quality of life in a patient with metastatic non-small cell lung cancer(NSCLC). A 51-year-old Korean female was referred to the $M{\cdot}{\mu}$ Integrative Cancer Center, East-West Neo Medical centrer, Kyung Hee University for stage IV, metastatic NSCLC. She was treated with aRVS alone for 19 months and then received 1st line paclitaxel/carboplatin combined with aRVS, 2nd line gefitinib, and 3rd line pemetrexed. The number of cycles of pemetrexed administered was seventeen. aRVS was restarted as the 13th pemetrexed was administered. Pemetrexed with aRVS is currently ongoing. This patient has been alive for 41 months, and has been keeping a good performance status so far. We suggest aRVS as sequential and concurrent treatment with chemotherapy is an effective alternative treatment strategy.
Our previous study showed that transgenic (TG) pigs harboring human EPO (hEPO) gene have been shown to have reproductive disorders, including low pregnancy rates, irregular estrus cycle and low little size. To investigate these reasons, we assessed estrus behavior (standing response) and plasma $17{\beta}$-estradiol ($E_2$) level, which partly reflect reproductive function, during the estrus cycles after synchronization and superovulation by hormone treatments. Then, we analysed blood composition and expression of hEPO gene in TG pigs. Pigs were injected with PG600. After 10 days, pigs were fed with Regumate porcine for 6 days. Blood samples were collected from jugular vein. Analysis of blood composition and $E_2$ level were measured by Hemavet 950 and $E_2$ ELISA kit, respectively. And, the expression of hEPO gene in reproductive organs was quantitated by real-time RT-PCR. The percentage of estrus behavior in TG was significantly decreased. Hematocrit (HCT), hemoglobin (Hb) concentration and red blood cell (RBC) number were significantly higher in TG than wild type (WT). On the other hand, high expression of hEPO gene in TG was observed in the mammary gland as well as in the uterus. Moreover, plasma $E_2$ level was significantly higher in TG than WT. These results suggest that nonspecific expression of hEPO gene in the other organs of TG may affect blood composition and plasma $E_2$ level, thereby causing reproductive disorders.
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