• 응용통계연구
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• 제11권2호
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• pp.257-268
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• 1998

역학연구에서 두 수준을 갖는 위험인자 X와 이항 반응변수 Y의 관계에 관심을 갖는 경우가 많다. 이 때 두 변수의 상관관계에 영향을 미칠 수 있는 인자 Z의 값을 제어함에 따라 X와 Y의 상관관계가 여전히 존재하는지를, 즉 X와 Y의 조건부 독립성을 검정할 필요가 있다 관측값의 수가 많지 않을 때, X와 Y의 조건부 독립성 검정을 위해 Mantel-Haenszel 검 정 이 널리 사용되고 있다. 하지 만 X와 Y의 상관관계가 Z의 수준에 따라 그 방향까지 변할 경우 이 검정은 낮은 검정력을 갖는다. 본 연구에서는 이 경우에 높은 검정력을 갖는 대안 검정통계량을 제안한다. 대안 검정통계량의 분포에 대해 알아보고 모의실험을 통해 Mantel-Haenszel 검정과 비교해 본다.

• Communications for Statistical Applications and Methods
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• 제24권6호
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• pp.663-671
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• 2017

Some genetic association tests include an unidentifiable nuisance parameter under the null hypothesis of no association. When the mode of inheritance (MOI) is not specified in a case-control design, the Cochran-Armitage (CA) trend test contains an unidentifiable nuisance parameter. The transmission disequilibrium test (TDT) in a family-based association study that includes the unaffected also contains an unidentifiable nuisance parameter. The hypothesis tests that include an unidentifiable nuisance parameter are typically performed by taking a supremum of the CA tests or TDT over reasonable values of the parameter. The p-values of the supremum test statistics cannot be obtained by a normal or chi-square distribution. A common method is to use a Davies's upper bound of the p-value instead of an exact asymptotic p-value. In this paper, we provide a unified sine-cosine process expression of the CA trend test that does not specify the MOI and the TDT that includes the unaffected. We also present a closed form expression of the exact asymptotic formulas to calculate the p-values of the supremum tests when the score function can be written as a linear form in an unidentifiable parameter. We illustrate how to use the derived formulas using a pharmacogenetics case-control dataset and an attention deficit hyperactivity disorder family-based example.

• Applied Biological Chemistry
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• 제20권3호
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• pp.285-291
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• 1977

(가) 2개 이상(以上) t개의 시료(試料)를 3점기호척도시험법(點嗜好尺度試驗法)에 의해 실험한 결과를 통계처리(統計處理)하여 t개 시료 상호간(相互間)의 품질차(品質差)를 비교(比較)하는 해석법(解析法)에 대해서 검토(檢討) 하였다. (나) 그 결과 $Scheff{\acute{e}}'s$ method의 제1신법(第1新法)이 품질차(品質差)의 검출력(檢出力)에서나 얻어지는 정보량(情報量)에서 우수(優秀)함을 확인하고 t개의 시료에 대할 3점기호척도시험법(點嗜好尺度試驗法)의 해석방법(解析方法)으로써 실용성(實用性)이 있다는 결론을 얻었다. (다) 이때 correct oddity chosen에 대한 incorrec toddity chosen의 weight fraction은 chance probability에 의해 계산하여 1/2로 하였다.

• Journal of the Korean Statistical Society
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• 제33권1호
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• pp.79-97
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• 2004

We propose a permutation approach to the classic Behrens-Fisher problem of comparing two means in the presence of unequal variances. It is motivated by the observation that a paired test is valid whether or not the variances are equal. Rather than using a single arbitrary pairing of the data, we average over all possible pairings. We do this in both a parametric and nonparametric setting. When the sample sizes are equal, the parametric version is equivalent to referral of the unpaired t-statistic to a t-table with half the usual degrees of freedom. The derivation provides an interesting representation of the unpaired t-statistic in terms of all possible pairwise t-statistics. The nonparametric version uses the same idea of considering all different pairings of data from the two groups, but applies it to a permutation test setting. Each pairing gives rise to a permutation distribution obtained by relabeling treatment and control within pairs. The totality of different mean differences across all possible pairings and relabelings forms the null distribution upon which the p-value is based. The conservatism of this procedure diminishes as the disparity in variances increases, disappearing completely when the ratio of the smaller to larger variance approaches 0. The nonparametric procedure behaves increasingly like a paired t-test as the sample sizes increase.

• Communications for Statistical Applications and Methods
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• 제19권3호
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• pp.451-457
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• 2012

Baumgartner et al. (1998) proposed a novel statistical test for the null hypothesis that two independently drawn samples of data originate from the same population, and Murakami (2006) generalized the test statistic for more than two samples. Whereas the expressions of the exact density and distribution functions of the generalized Baumgartner statistic are not yet found, the characteristic function of its limiting distribution has been obtained. Due to the development of computational power, the Fourier series approximation can be readily utilized to accurately and efficiently approximate its density function based on its Laplace transform. Numerical examples show that the Fourier series method provides an accurate approximation for statistical quantities of the generalized Baumgartner statistic.

• 대한수학회지
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• 제47권2호
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• pp.385-407
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• 2010

To study the relationship between the levels of chemical pollutants and the number of daily total hospital admissions for respiratory diseases and to find the effect of temperature/relative humidity on the admission number, Wong et al. [17] introduced the varying-coefficient single-index model (VCSIM). As pointed out, it is a popular multivariate nonparametric fitting technique. However, the tests of the model have not been very well developed. In this paper, based on the estimators obtained by the local linear technique, the average method and the one-step back-fitting technique in the VCSIM, the generalized likelihood ratio (GLR) tests for varying-coefficient parts on the VCSIM are established. Under the null hypotheses the new proposed GLR tests follow the $\chi^2$-distribution asymptotically with scale constant and degree of freedom independent of the nuisance parameters, known as Wilks phenomenon. Simulations are conducted to evaluate the test procedure empirically. A real example is used to illustrate the performance of the testing approach.

• Communications for Statistical Applications and Methods
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• 제12권1호
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• pp.71-86
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• 2005

Testing for normality has always been an important part of statistical methodology. In this paper a test statistic for multivariate normality is proposed. The underlying idea is to investigate all the possible linear combinations that reduce to the standard normal distribution under the null hypothesis and compare the order statistics of them with the theoretical normal quantiles. The suggested statistic is invariant with respect to nonsingular matrix multiplication and vector addition. We show that the limit distribution of an approximation to the suggested statistic is representable as the supremum over an index set of the integral of a suitable Gaussian process.

• Communications for Statistical Applications and Methods
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• 제9권2호
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• pp.389-399
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• 2002

In order to examine whether the difference between two point estimates of population proportions is statistically significant, data analysts use two techniques. The first is to explore the overlap between two associated confidence intervals. Second method is to test the significance which is introduced at most statistical textbooks under the common assumptions of consistency, asymptotic normality, and asymptotic independence of the estimates. Under the null hypothesis which is two population proportions are equal, the pooled estimator of population proportion is preferred as a point estimator since two independent random samples are considered to be collected from one population. Hence as an alternative method, we could obtain another confidence interval of the difference of the population proportions with using the pooled estimate. We conclude that, among three methods, the overlapped method is under-estimated, and the difference of the population proportions method is over-estimated on the basis of the proposed method.

• 응용통계연구
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• 제4권1호
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• pp.33-45
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• 1991

변화시점 모형은 지금까지 한 시점에서 단 한 개의 관측자료를 갖는 모형만 생각해 왔다. 이러한 모형을 확장시켜 각 시점에 한 개 이상의 관측자료를 갖는 변화시점 모형을 생각한다. 이러한 모형에서 비모수적인 단측 그리고 양측 검정법을 찾았다. 검정 통계량은 지금까지 소개된 검정 통계량 형태를 확장시킨 형태이고 이들의 귀무가설 분포를 구하여 보았다. 또한 Monte Carlo연구를 통해 이들의 검정력을 비교해 보았다.

• 대한의용생체공학회:학술대회논문집
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• 대한의용생체공학회 1993년도 추계학술대회
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• pp.141-144
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• 1993

This paper propose a two pole phase compensated titer to remove baseline wandering and preserve ST-segment accuracy in real time environment. Bilinear transformed null phase filter(ideal filter), Standard FIR filter and Cubic spline filter are evalauated in the same condition. The proposed phase compensated filter shows better performance than standard filter in real ECG test and triangular pulse test.