• 제목/요약/키워드: nucleotide-related compounds

검색결과 57건 처리시간 0.028초

꽃게 통발용 미끼로서의 고등어와 다랑어 내장의 이화학적 특성 (Physicochemical characteristics of mackerel and tuna viscera as baits for swimming crab Portunus trituberculatus pots)

  • 구재근;장호영
    • 수산해양기술연구
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    • 제50권3호
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    • pp.310-317
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    • 2014
  • This study was conducted to investigate the attractant substances of different solvent fractions of mackerel and tuna viscera. Mackerel and tuna viscera were extracted with methanol and the resultant were fractionated with n-hexane, chloroform, ethyl acetate, n-butanol and water. The chemical compounds such as free amino acid, fatty acid, nucleotide related compounds contents were estimated for mackerel, tuna viscera and various fractions. These fractions were also subjected to attracting experiments in water tank to estimate attracting effects. The aqueous fractions of mackerel and tuna viscera showed the highest attraction effect on swimming crab. The major chemical compounds of the aqueous fractions were histidine, taurine, cysteine, glutamic acid, inosine monophosphate (IMP) and inosine (HxR) for mackerel and arginine, glutamic acid, aspartic aid, alanine, IMP and hypoxanthin (Hx). Results indicated that higher polarity compounds, such as amino acid and nucleotide related compounds have higher attraction activities than nonpolar substances such as neutral lipid.

곰팡이 발효소시지의 숙성에 따른 기호적 품질 특성의 변화 (changes of Palatability Traits of Mold Fermented Sausages during Ripening)

  • 고명수
    • 한국축산식품학회지
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    • 제18권1호
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    • pp.57-62
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    • 1998
  • Changes of palatability traits such as color texture free amino acid and nucleotide-related compound of mold fermented sausages during ripening were investigated. The a-value of mold fermented sausages rapidly increased up to 7th days if ripening. The hardness of mold fermented sausages rapidly increased while springiness and cohesiveness slightly decreased during ripening. Total free amino acid of mold fermented sausages gradually increased during ripening. Contents of nucleotide-related compounds such as ATP, ADP, AMP and IMP of mold fermented sausages rapidly decreased during ripening.

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건조 홍합 및 바지락의 저장 중 핵산관련물질 및 유기염류의 변화 (Changes in Contents of Some Taste Compounds of Dried Mussel and Baby Clam during Storage)

  • 주옥수;서권일;이용수;이종호;최상도;심기환
    • 한국식품과학회지
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    • 제28권5호
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    • pp.882-887
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    • 1996
  • 홍합과 바지락의 건조 및 저장조건에 따른 핵산 및 그 관련물질과 유기염류의 함량변화를 조사한 결과는 다음과 같다. 홍합과 바지락 모두에서 ATP, ADP, AMP, inosine, adenosine 및 hypoxanthine의 6성분을 분석하였다. 홍합과 바지락 모두 생시료의 경우 adenosine의 함량이 높았으며, 건조 및 저장에 의해 ATP, ADP 및 AMP의 함량은 감소하고 inosone 및 hypoxanthine의 함량은 증가하였다. 그리고, TMAO, TMA및 총 creatinine의 함량은 두 시료 모두 함량이 아주 낮았으며, 건조 및 저장에 의해 TMAO 및 총 creatinine의 함량은 감소한 반면 TMA의 함량은 증가하였다.

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3배체잉어 근육의 식품성분에 관한 연구 1. 3배체잉어 근육의 정미성분 (Studies on the Food Components of Triploid Carp Muscle 1. The Taste Compounds of Triploid Carp Muscle)

  • 이응호;정부길;김진수;안창범;오광수
    • 한국수산과학회지
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    • 제22권3호
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    • pp.154-160
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    • 1989
  • 일반양식어(2배체)에 비해 사료효율이 높고, 성장율이 좋은 3배체잉어에 대한 식품학적 기초자료를 얻고자 비산란기 2배체잉어와 3배체잉어의 식품성분을 비교$\cdot$검토하였으며 아울러 산란기 2배체잉어와도 비교하였다. 일반성분은 비산란기 2배체잉어 및 3배체잉어가 산란기 2배체잉어에 비하여 수분함량은 낮았으며 조지방은 오히려 높았다. 배쪽육 및 등쪽육의 총유 리아미노산함량은 비산란기 2배체잉어가 각각 363.0mg/100g, 357.8mg/100g으로 가장 많았고, 다음으로 3배체잉어 (346.1mg/100g, 333.4mg/100g), 산란기 2배체잉어(329.5mg/100g, 326.0mg/100g)의 순이었다. 시료어 및 근육의 종류에 관계없이 함량이 많은 유리 아미노산으로는 histidine, taurine, Iysine 및 glycine 등이었고, 이들은 전체의 $77.5\~83.2\%$를 차지하였으며, 그 중에서도 특히 histidine 함량이 많았다. 핵산관련물질함량은 시료어 및 근육의 종류에 관계없이 IMP함량($179.4\~198.4mg/100g$)이 가장 많았고, 다음으로 ATP함량이 많았으며, ADP, AMP, inosine 등은 미량 검출되었다. 시료어 및 근육의 종류에 따른 핵산관련물질함량의 차이는 거의 없었다. 총creatinine함량은 근육종류에 관계없이 거의 유사하였으나, 시료어간에 있어 서는 비산란기 2배체잉어가 함량이 가장 많았고, 다음으로 3배체잉어, 산란기 2배체잉어의 순이었다. betaine함량은 $63.5\~66.1mg/100g$으로 시료간에 거의 차이가 없었으며 TMAO는 모든 시료구에서 미량 검출되었다. 함량으로 미루어 보아 3배체 잉어의 맛에는 유리아미노산, 핵산관련물질 및 총creatinine의 순으로 관여하리라 생각된다. 3배체잉어의 총구성아미노산함량은 근육의 종류에 관계없이 비산란기 및 산란기 2배체잉어에 비하여 약간 적었으나 큰 차이는 없었다. 무기질에 있어서는 3배체잉어가 비산란기 2배체잉어에 비하여 인 및 철의 함량은 약간 적었으나 칼슘의 함량은 오히려 많았다. 이상의 결과로부터 3배체잉어는 비산란기 2배체잉어와 비교하여 볼 때 맛성분 및 영양성분에 약간 적었지만 큰 차이는 없었고, 산란기 2배체잉어보다는 그 함량이 많아 성(性)적 성숙기 및 산란기가 없는 3배체잉어는 식품원료학적으로 가치 있다는 결론을 얻었다.

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Effect of Sex on Flavor-related and Functional Compounds in Freeze-dried Broth Made from Korean Native Chicken

  • Jayasena, Dinesh D.;Jung, Samooel;Kim, Hyun Joo;Alahakoon, Amali U.;Nam, Ki Chang;Jo, Cheorun
    • 한국축산식품학회지
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    • 제34권4호
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    • pp.448-456
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    • 2014
  • Studies on the flavour characteristics of meat-based broth, quantification of flavour-related and functional compounds, and factors affecting the availability of such compounds are minimal. The present study was designed to determine the effects of sex on flavor-related and functional compounds in freeze-dried broth (FDB) made from Korean native chickens (KNC). Male and female KNC from a commercial strain (Woorimatdag$^{TM}$) were reared under similar commercial conditions. FDB was separately prepared using male and female birds aged 100 d (six birds of each sex) and analyzed for nucleotide, free amino acid, betaine, carnitine, carnosine, anserine, and creatine contents, and fatty acid composition. The levels of betaine, carnitine and creatine in FDB were not significantly different between the two sexes (p>0.05) in KNC. Carnosine and anserine were not detected in FDB samples. However, FDB from female chickens had significantly higher inosine-5-monophosphate and arachidonic acid contents than did FDB from male chickens. FDB prepared with male KNC contained higher levels of inosine, linoleic acid, glycine, alanine, lysine, and serine (p<0.05). However, glutamic acid, oleic acid, and DHA were present in comparable amounts (p>0.05) in FDB made from male and female KNC. Our findings suggest that the sex of KNC has significant effect on the contents of flavor-related compounds, but not functional compounds.

담수어(淡水魚)의 식품학적(食品學的) 연구(硏究)(II)-붕어, 메기, 가물치 및 미꾸리의 맛성분(成分)- (Studios on the Food from Fresh Water Fish(II)-The Taste Compounds in Meat of Crucian Carp, Skate$\cdot$Fish, Snake Head and Loaches-)

  • 성낙주;심기환
    • Journal of Nutrition and Health
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    • 제14권2호
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    • pp.80-86
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    • 1981
  • Crucian carp Carassius carassius L., Skate-fish Parasilurus asolus, snake head Ophicephalus argus and loaches Misgrunus anguillicaudatus have been esteemed as the tasty fresh water fish in Korea. However, a little has been studied on their taste compounds. Amino acids, nucleotides and their related compounds as the taste giving substance in the dorsal muscle of crucian carp, skate-fish, snake head and loaches were analyzed. Hypoxanthine (4.6-30.3 ${\mu}mole/g$, on dry base) was dominant among the nucleotide materials in the dorsal muscle of crucian carp, skate-fish, and snake head while IMP (12.8 ${\mu}mole/g$) was detected with the highest amount in loaches meat. IMP was also high in the muscle of skate-fish (13.5 ${\mu}mole/g$) and snake head (5.6 ${\mu}mole/g$). The other nucleotide materials, CMP, UMP, GMP, AMP, and inosine were present less than 2.0 ${\mu}mole/g$ in all the fish meat. The amino acid composition showed that glutamic acid and aspartic acid were the most abundant in the dorsal muscle of crucian carp, skate-fish, snake head and loaches. The analysis of free amino acids showed that histidine, lysine, glycine, and serine were the leading amino acids in the dorsal muscle of crucian carp, alanine, serine, and lysine were of skatefish, glycine, lysine, alanine, and serine were of snake head, while alanine, serine, and glycine were of loaches. Isoleucine and leucine were detected in trace amount in the muscle of skate-fish, snake head, and loaches. It is believed that alanine, Iysine, serine, glycine and histidine along with IMP and hypoxanthine may play an important role as the taste compounds in fresh water fish.

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마늘 첨가가 저염 멸치젓의 품질에 미치는 영향 - 제2보 함질소화합물의 변화 - (Effect of Garlic on Quality of Low Salted Anchovy - 2. Changes of Nitrogenous Compounds -)

  • 진양호;권오천;성낙주;신정혜;강민정
    • 한국조리학회지
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    • 제8권3호
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    • pp.279-294
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    • 2002
  • The anchovy, Engraulis japonica, were prepared with two different salt concentration of 20%, 10% which was added 2, 5, 5 and 10 % of grind garlic(LSA 1, 2, 3, 4) and garlic juice(LSB 1, 2, 3, 4), respectively. The experimental samples were taken at 30, 60, 90 and 110 days fermentation, which were analyzed VBN(volatile basic nitrogen), amino acids, nucleotides and their related compounds and amino acids. VBN increased rapidly until 110 days fermentation, its contents in samples containing of 10% salt(CB) were increased about 2.4 times as compared with those of 30 days fermentation. And then its contents of 110 days fermented samples increased at average 2.3 times more than 30 days fermented samples containing grind garlic of 2, 5, 8% and garlic juice of 2%. Nucleotide and their related compounds were detected AMP, UMP, IMP, inosine and hypoxanthine. Hypoxanthine was dominants in all samples and increased steadily during fermentation of anchovy. The contents of composition amino acids decreased gradually during it's fermentation, but those content decreased 33% in CO group, 42% in the CB group and 38%(average) in the other garlic added low salt groups.

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Changes in Nucleotide Compounds, and Chemical and Sensory Qualities of Duck Meat during Aging at 0℃

  • Kim, Young-Boong;Ku, Su-Kyung;Joo, Bum-Jin;Lee, Nam-Hyuck;Jang, Ae-Ra
    • 한국축산식품학회지
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    • 제32권4호
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    • pp.428-433
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    • 2012
  • The objective of this study was to identify appropriate aging conditions, changes in nucleotide-related compounds, chemical changes, and a sensory evaluation of duck meat during aging at $0^{\circ}C$ for 7 d. Twenty one 45-day-old Pekin white ducks samples were separated into breast and leg meat. ATP was not detected for almost the entire aging period because ATP was depleted immediately after slaughter. Inosine monophosphate (IMP) was highest on day 1 ($26.69{\mu}mol/g$), and then it rapidly decreased to $7.11{\mu}mol/g$ on day 7. However, this level was not different between breast and leg meat. Hypoxanthine (Hx) content of breast meat was $14.88{\mu}mol/g$, whereas that of leg meat was $16.41{\mu}mol/g$. Inosine content of breast meat was double than that of leg meat. The pH values of breast and leg meat were 5.90-6.05 and 6.23-6.73, respectively, during the aging period. Volatile basic nitrogen content of breast and leg meat increased during aging. Breast meat had good sensory evaluation scores for flavor (7.4), juiciness (6.8), tenderness (7.2), and overall acceptance (7.4) on day 3. Similar to breast meat, leg meat also had good sensory evaluation scores. Therefore, it is concluded that the appropriate aging period is 3 d for duck breast meat and 1 day for leg meat at $0^{\circ}C$.

영아자 (Phyteuma japonicum Miq)의 성분 조성 (Chemical Components of Wid and Cultivated Horned Rampion, Phyteuma japonicum Miq.)

  • 정미자;신정혜;이수정;홍성국;강호중;성낙주
    • 한국식품영양학회지
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    • 제11권4호
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    • pp.437-443
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    • 1998
  • This research is to establish the basic data of the nutritive value and improve our diet. In the part of the leaf and stem of the wild and cultivated horned rampion (Phyteuma japonicum Mig), the components such as chemical compositon, vitamin C, free sugar, mineral, nucleotide and its related compounds, composition and free amino acid were analyzed one after another. Content of the crude lipids and proteins was determined much higher in its wildness than in its cultivated horned rampion; while, that of carbohydrates was higher in the former than in the latter. The content of vitamin C was retained higher in the leaf than in the stem horned rampion. And the content of calcium among the detected minerals was outstanding in all of the samples collected, and potassium and magnesium was the next ones in its order. The main components of free sugars in both the wild and cultivated horned rampion were glucose and fructose, and their content was higher in the stem than in the leaf. Nucleotide and its related compounds were identified with 5 kinds of nucieotides such as CMP, UMP, IMP, AMP and hypoxanthine (Hx), and the content of Hx and AMP was the highest I the wild and cultivated samples, respectively. In the composition amino acid of the wild horned rampion, glutamic acid, aspartic acid and phenylalanine was outstandingly abundant; while, such amino acid as methinone and proline was small and besides cysteine couldn't be detected in the stem. Total amounts of composition amino acid in the leaf was 2118.0 and 1120.1mg% in the wild and cultivated sample, respectively. In the free amino acid of horned rampion, the total amount ranged from 8.5 to 50.1mg.%, which were lower level than that of composition amino acid. But the number of free amino acid was 29 kinds, which was bigger in its number than that of composition amino acid detected 17 kinds.

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Interruption of Helicobacter pylori-Induced NLRP3 Inflammasome Activation by Chalcone Derivatives

  • Choi, Hye Ri;Lim, Hyun;Lee, Ju Hee;Park, Haeil;Kim, Hyun Pyo
    • Biomolecules & Therapeutics
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    • 제29권4호
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    • pp.410-418
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    • 2021
  • Helicobacter pylori causes chronic gastritis through cag pathogenicity island (cagPAI), vacuolating cytotoxin A (VacA), lipopolysaccharides (LPS), and flagellin as pathogen-related molecular patterns (PAMPs), which, in combination with the pattern recognition receptors (PRRs) of host cells promotes the expression and secretion of inflammation-causing cytokines and activates innate immune responses such as inflammasomes. To identify useful compounds against H. pylori-associated gastric disorders, the effect of chalcone derivatives to activate the nucleotide-binding oligomerization domain (NOD)-like receptor family, pyrin domain-containing 3 (NLRP3) inflammasome was examined in an H. pylori-infected human monocytic THP-1 cell line in this study. Among the five synthetic structurally-related chalcone derivatives examined, 2'-hydroxy-4',6'-dimethoxychalcone (8) and 2'-hydroxy-3,4,5-trimethoxychalcone (12) strongly blocked the NLRP3 inflammasome in H. pylori-infected THP-1 cells. At 10 μM, these compounds inhibited the production of active IL-1β, IL-18, and caspase-1, and apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC) oligomerization, but did not affect the expression levels of NLRP3, ASC, and pro-caspase-1. The interruption of NLRP3 inflammasome activation by these compounds was found to be mediated via the inhibition of the interleukin-1 receptor-associated kinase 4 (IRAK4)/IκBα/NF-κB signaling pathway. These compounds also inhibited caspase-4 production associated with non-canonical NLRP3 inflammasome activation. These results show for the first time that certain chalcones could interrupt the activation of the NLRP3 inflammasome in H. pylori-infected THP-1 cells. Therefore, these chalcones may be helpful in alleviating H. pylori-related inflammatory disorders including chronic gastritis.