• Journal of Institute of Control, Robotics and Systems
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• v.10 no.12
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• pp.1155-1163
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• 2004

Extracellular signal-regulated kinase (ERK) signaling pathway is one of the mitogen-activated protein kinase (MAPK) signal transduction pathways. This pathway is known as pivotal in many signaling networks that govern proliferation, differentiation and cell survival. The ERK signaling pathway comprises positive and negative feedback loops, depending on whether the terminal kinase stimulates or inhibits the activation of the initial level. In this paper, we attempt to model the ERK pathway by considering both of the positive and negative feedback mechanisms based on Michaelis-Menten kinetics. In addition, we propose a fraction ratio model based on the mass action law. We first develop a mathematical model of the ERK pathway with fraction ratios. Secondly, we analyze the dynamical properties of the fraction ratio model based on simulation studies. Furthermore, we propose a concept of an inhibitor, catalyst, and substrate (ICS) controller which regulates the inhibitor, catalyst, and substrate concentrations of the ERK signal transduction pathway. The ICS controller can be designed through dynamical analysis of the ERK signaling transduction pathway within limited concentration ranges.

• 제어로봇시스템학회:학술대회논문집
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• 1998.10a
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• pp.451-454
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• 1998

This paper proposes a new method of Model Predictive Control (MPC) of nonlinear process by us-ing the measured Volterra kernels as the nonlinear model. A nonlinear dynamical process is usually de-scribed as Volterra kernel representation, In the authors' method, a pseudo-random M-sequence is ar plied to the nonlinear process, and its output is measured. Taking the crosscorrelation between the input and output, we obtain the Volterra kernels up to 3rd order which represent the nonlinear characteristics of the process. By using the measured Volterra kernels, we can construct the nonlinear model for MPC. In applying Model Predictive Control to a nonlinear process, the most important thing is, in general, what kind of nonlinear model should be used. The authors used the measured Volterra kernels of up to 3rd order as the process model. The authors have carried out computer simulations and compared the simulation results for the linear model, the nonlinear model up to 2nd Volterra kernel, and the nonlinear model up to 3rd order Vol-terra kernel. The results of computer simulation show that the use of Valterra kernels of up to 3rd order is most effective for Model Predictive Control of nonlinear dynamical processes.

• Structural Engineering and Mechanics
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• v.23 no.6
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• pp.599-613
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• 2006

A method for the dynamical analysis of FE discretized uncertain linear and nonlinear structures is presented. This method is based on the moment equation approach, for which the differential equations governing the response first and second-order statistical moments must be solved. It is shown that they require the cross-moments between the response and the random variables characterizing the structural uncertainties, whose governing equations determine an infinite hierarchy. As a consequence, a closure scheme must be applied even if the structure is linear. In this sense the proposed approach is approximated even for the linear system. For nonlinear systems the closure schemes are also necessary in order to treat the nonlinearities. The complete set of equations obtained by this procedure is shown to be linear if the structure is linear. The application of this procedure to some simple examples has shown its high level of accuracy, if compared with other classical approaches, such as the perturbation method, even for low levels of closures.

• Journal of Advanced Marine Engineering and Technology
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• v.20 no.2
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• pp.101-101
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• 1996

This paper presents the linearized fuzzy modeling technique of nonlinear dynamical system and the stability analysis of fuzzy control system. Firstly, the nonlinear system is partitionized by multiple linear fuzzy subcontrol systems based on fuzzy linguistic variables and fuzzy rules. Secondly, the disturbance adaptaion controllers which guarantee the global asymptotic stability of each fuzzy subsystem by an optimal feedback control law are designed and the stability analysis procedures of the total fuzzy control system using Lyapunov functions and eigenvalues are discussed in detail through a given illustrative example.

• Journal of the Institute of Convergence Signal Processing
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• v.2 no.1
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• pp.95-100
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• 2001

In this paper, we proposed the robust control scheme for a class of nonlinear dynamical systems using output feedback linearization method. The presented control scheme is based on the VSS. We assume that the nonlinear dynamical system is minimum phase, the relative degree of the system is r＜n and zero dynamics is stable. It is also shown that the global asymtotically stability is guaranted. And we verified that the proposed control scheme Is the feasible through a computer simulation.

• 제어로봇시스템학회:학술대회논문집
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• 1993.10b
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• pp.81-87
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• 1993

In this paper robust stability conditions are obtained for linear dynamical systems under structured nonlinear time-varying perturbations, using absolute stability theory and the concept of dissipative systems. The conditions are expressed in terms of solutions to linear matrix inequality(LMI). Based on this result, a synthesis methodology is developed for robust feedback controllers with worst-case H$_{2}$ perforrmance via convex optimization and LMI formulation.

• 제어로봇시스템학회:학술대회논문집
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• 2002.10a
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• pp.83.5-83
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• 2002

Perspective dynamical systems arise in machine vision, in which only perspective observation is available, and the essential problem is to estimate the state and /or unknown parameters for a moving rigid body based on the observed information. This paper proposes and studies a Luenberger-type observer for perspective tim e-varying linear systems. In particular, assuming a given perspective time-varying linear system to be Lyapunov stable and to satisfy some sort of observability condition, it is shown that the estimation error converges exponentially to zero. Finally, a simple numerical exam pie is presented to illustrate the result obtained.

• 제어로봇시스템학회:학술대회논문집
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• 1999.10a
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• pp.141-144
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• 1999

The authors have recently developed a new method for identification of Volterra kernels of nonlinear systems by use of pseudorandom M-sequence and correlation technique. And it is shown that nonlinear systems which can be expressed by Volterra series expansion are well identified by use of this method. However, there exist many nonlinear systems which can not be expressed by Volterra series mathematically. A nonlinear system having backlash type nonliear element is one of those systems, since backlash type nonlinear element has multi-valued function between its input and output. Since Volterra kernel expression of nonlinear system is one of the most useful representations of non-linear dynamical systems, it is of interest how the method of Volterra kernel identification can be ar plied to such backlash type nonlinear system. The authors have investigated the effect of application of Volterra kernel identification to those non-linear systems which, accurately speaking, is difficult to express by use of Volterra kernel expression. A pseudorandom M-sequence is applied to a nonlinear backlash-type system, and the crosscorrelation function is measured and Volterra kernels are obtained. The comparison of actual output and the estimated output by use of measured Volterra kernels show that we can still use Volterra kernel representation for those backlash-type nonlinear systems.

• 제어로봇시스템학회:학술대회논문집
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• 2001.10a
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• pp.39.2-39
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• 2001

This paper describes the design of an output-feedback controller based on an adaptive fuzzy observer for uncertain single-input single-output nonlinear dynamical systems. Especially, we have focused on the realization of minimal dynamic order of the adaptive fuzzy observer. For the purpose, we propose a new method in which no strictly positive real(SPR) condition is needed and combine dynamic rule activation scheme with on-line estimation of fuzzy parameters. By using proposed scheme, we can reduce computation time, storage space, and dynamic order of the adaptive fuzzy observer ...

• Proceedings of the Korean Institute of Intelligent Systems Conference
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• 2001.05a
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• pp.191-194
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• 2001

The ozone forecasting systems have many problems because the mechanism of the ozone concentration is highly complex, nonlinear, and nonstationary. Also, the results of prediction are not a good performance so far, especially in the high-level ozone concentration. This paper describes the modeling method of the ozone prediction system using neuro-fuzzy approaches and fuzzy clustering. The dynamic polynomial neural network (DPNN) based upon a typical algorithm of GMDH (group method of data handling) is a useful method for data analysis, identification of nonlinear complex system, and prediction of a dynamical system.