• Title/Summary/Keyword: none-technology

Search Result 432, Processing Time 0.032 seconds

Synthesis and Biological Effects of Some 5-Heterocyclicmethyl-2'-deoxyurdines

  • Kwak, In-Young;Ryu, Eung K.
    • Archives of Pharmacal Research
    • /
    • v.13 no.4
    • /
    • pp.306-309
    • /
    • 1990
  • The synthesis of 5-hyterocyclimethyl-2'-deoxyuridines (4a-f) has been accomplished by displacement reaction of 5-(bromomethyl)-3', 5'-di-O-acetyl-2'-deoxyuridine with heterocyclic compounds, followed by removal of acetyl protecting group with methanolic ammonia. The compoudns synthesized were evaluated the inhibitory effects on L1210 cell probiferation and antiviral activities against Herpes simplex virus type 1 (HSV-1) None of the compounds exhibited sufficient biological activities.

  • PDF

Evaluation on the Usefulness of X-ray Computer-Aided Detection (CAD) System for Pulmonary Tuberculosis (PTB) using SegNet (X-ray 영상에서 SegNet을 이용한 폐결핵 자동검출 시스템의 유용성 평가)

  • Lee, J.H.;Ahn, H.S.;Choi, D.H.;Tae, Ki Sik
    • Journal of Biomedical Engineering Research
    • /
    • v.38 no.1
    • /
    • pp.25-31
    • /
    • 2017
  • Testing TB in chest X-ray images is a typical method to diagnose presence and magnitude of PTB lesion. However, the method has limitation due to inter-reader variability. Therefore, it is essential to overcome this drawback with automatic interpretation. In this study, we propose a novel method for detection of PTB using SegNet, which is a deep learning architecture for semantic pixel wise image labelling. SegNet is composed of a stack of encoders followed by a corresponding decoder stack which feeds into a soft-max classification layer. We modified parameters of SegNet to change the number of classes from 12 to 2 (TB or none-TB) and applied the architecture to automatically interpret chest radiographs. 552 chest X-ray images, provided by The Korean Institute of Tuberculosis, used for training and test and we constructed a receiver operating characteristic (ROC) curve. As a consequence, the area under the curve (AUC) was 90.4% (95% CI:[85.1, 95.7]) with a classification accuracy of 84.3%. A sensitivity was 85.7% and specificity was 82.8% on 431 training images (TB 172, none-TB 259) and 121 test images (TB 63, none-TB 58). This results show that detecting PTB using SegNet is comparable to other PTB detection methods.

Research on the Implementation of 5G SA Test Network Test Bed Function Based on Service-Based Architecture (SBA 기반 5G SA 시험망 시스템 기능 구현에 관한 연구)

  • Park, Jea-Seok;Yoon, Mahn-Suk
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
    • /
    • 2022.05a
    • /
    • pp.529-531
    • /
    • 2022
  • The 5th generation mobile communication (5G) is being commercialized by major domestic and foreign mobile telecommunication businesses and is spreading to general customers mainly on smart devices such as smartphones, wearables, and IoT. If 4G networks and 5G access equipment were utilized by introducing NSA(None-Stand Alone) technology when 5G was first introduced, recently, 5G convergence services are being realized by gradually expanding evolution to 5G standalone networks through SA (Stand Alone) technology. The purpose of this study is to study a design plan for implementing necessary service-oriented functions from the perspective of communication network users on the configuration of 5G SA equipment based on SBA(Service-based Architecture) mentioned in the 3GPP technical specification document. Through this research, it is expected that companies that need to enter the 5G market can easily access the 5G SA network to develop and supplement specialized 5G convergence services to improve product performance and quality.

  • PDF

Flexural Behavior of iFLASH System with No Blast Metal Cleaned Steel Plates (비표면처리 강판을 사용한 iFLASH 시스템의 휨성능 평가)

  • Kim, Yong-Yeal;Ryu, Jaeho;Yoon, Sung-Won;Ju, Young K.
    • Journal of the Korean Society for Advanced Composite Structures
    • /
    • v.6 no.4
    • /
    • pp.30-37
    • /
    • 2015
  • iFLASH System is new structural floor system which consists of sandwich panels filled with nano-composite. The nano-composite has low specific gravity and high bonding strength with steel plates. The bonding strength is one of important factors for structural performance of iFLASH System and it can further be improved by surface preparation such as blast metal cleaning. However, using none blast steel plates is recommended since surface preparation generates additional fabrication time and cost. In this study, a bonding strength test and bending experiment were conducted to check feasibility of applying none blast steel plates to iFLASH System. Moreover, stress in bonding plane between steel plates and nano-composite was analytically evaluated by finite element method. Consequently, flexural capacity of the specimen was 11% higher than theoretically calibrated value and its flexural behavior was structurally efficient without defect of bonding.

Proposal for Increase of Thermal Margin in COLSS

  • Lee, Byung I.;Kim, Du I.;Kim, Jong J.;Kil S. Um;Lee, Chong C.
    • Proceedings of the Korean Nuclear Society Conference
    • /
    • 1997.05a
    • /
    • pp.508-513
    • /
    • 1997
  • One of the moot important constants to be Installed In COLSS, a monitoring system in CE typed reactors, is ROPM which would limit the operating space. This static ROPM was calculated from digital transient analysis assuming that every design basis transient was initiated from the most severe initial condition combination (LCO). Once It could be assured that core condition would not be located at none other than LCO, this static ROPM could be replaced with dynamic ROPM calculated at that condition and the dynamic ROPM would be definitely less than the static ROPM. In order to do, It must be required to calculate the transient discrete sensitivity parameters and parameters change distribution. The purpose of this report is just to propose the enlargement method for thermal margin.

  • PDF

Synthesis and Antibacterial Activity of $7{\beta}$-[2-(Substituted Benzylthio) Alkanamido] Cephalosporins ($7{\beta}$-[2-(치환 Benzylthio) Alkanamido] Cephalosporins의 합성 및 항균작용)

  • Park, Jung-Sup;Kim, Kang-Yual;Ryu, Eung-Kul
    • YAKHAK HOEJI
    • /
    • v.32 no.4
    • /
    • pp.222-229
    • /
    • 1988
  • A series of substituted benzylthioalkanamidocephalosporins 3a-3p were synthesized and tested in vitro antibacterial activity. Of these new cephalosporins exhibited good antibacterial activity against Gram-positive bacteria whereas none of the compounds possessed the activity against Gram-negative bacteria at the concentration tested.

  • PDF

A Study on the Biomedical Ethics Consciousness for Euthanasia of the Paramedic Students (응급구조학과 대학생들의 안락사에 대한 생명의료윤리 의식 연구)

  • Choi, Bo-Ram
    • The Korean Journal of Emergency Medical Services
    • /
    • v.14 no.2
    • /
    • pp.41-55
    • /
    • 2010
  • Objective : This study is designed to present the direction and the necessity of education on the biomedical ethics the establish desirable ethical view of paramedic students by understanding on the consciousness of students of department of emergency medical technology on biomedical ethics on euthanasia. Method : Data were collected from on 335 students of department of emergency medical technology in 4-year-college located in districts of Chungcheong-do, from March 4 to April 22, 2010. The questionnaire consisted of total 29 items, i.e., 11 items of general characteristics, 11 items of characteristics related to biomedical ethics and 7 items of consciousness on euthanasia. Result : In general characteristics, the first grade showed the most dense distribution of 37.3%, the second grade was 20.0%, the third grade was 20.9% and the fourth grade was 21.8%. In the consciousness of biomedical ethics on euthanasia, the third and the fourth grades showed a higher ratio(${\chi}^2$ = 136.327, p= .000), in comparison with the first and the second grades, the higher year they were, the higher degree of consciousness they had. The consciousness on each item of euthanasia showed significant differences in grade (F = 8.203, p= .000), experience of clinical practice or none (t = 3.731, p= .000), experience of biomedical ethics education or none (t = 1.997, p = .047) and degree of consciousness on DNR (F = 8.240, p = .000) regarding 'CPR shall not be required in any cases if a patient wants DNR', in experience of biomedical ethics education or none (t = 2.452, p= .015) and degree of consciousness on DNR (F = 2.725, p = .044) regarding if a patient refuses all treatments, the patient's opinion shall be respected', and in degree of consciousness on DNR (F = 2.858, p = . 037) regarding 'after determination of DNR, if the family wants a positive treatment, it shall follow the family's request'. Conclusion : It seemed that the differences in consciousness according to grade and experience of clinical practice were influenced by experiences to treat patients in personally. Moreover, it showed that the higher grade they are, the more experience of education they have, the experiences of education had influences on the consciousness. Development of educational programs is required in order to supply accurate knowledge on biomedical ethics for euthanasia to lower-grade students the to let them establish ethical views properly, and in order to correct wrong knowledge and to establish ethical views while supplying knowledge on biomedical ethics for euthanasia to higher-grade students.

  • PDF

Influence of Soil and Forage Minerals on Buffalo (Bubalus bubalis) Parturient Haemoglobinuria

  • Akhtar, M.Z.;Khan, A.;Sarwar, M.;Javaid, A.
    • Asian-Australasian Journal of Animal Sciences
    • /
    • v.20 no.3
    • /
    • pp.393-398
    • /
    • 2007
  • The present study was carried out to investigate the serum minerals profile in buffaloes (Bubalus bubalis) suffering from parturient haemoglobinuria (PHU) along with minerals profile of soils and fodders from the disease prone areas and their interrelationships. Serum samples were collected from 60 each of healthy and PHU affected buffaloes randomly selected from field cases. Serum samples were collected from each animal. Fifty composite soil samples were collected where PHU was prevalent. Fifty samples of fodders including leaves and stems being fed to the diseased buffaloes were collected. The difference in the levels of calcium and potassium between upper and lower soil surface of disease prone areas under study were statistically non-significant. The mean values of phosphorous, copper, iron, selenium and molybdenum in upper soil surface were significantly (p<0.05) higher than in lower soil surface. None of the fodders offered to the diseased animals met the dietary requirements of phosphorus and copper whereas none of the fodders was deficient in potassium, iron and selenium rather were having excess of potassium, iron and selenium. The concentration of calcium was adequate in lucerne, berseem, sarson and sorghum, while maize, sugarcane and wheat straw did not meet the required levels for dairy animals. Molybdenum contents in all fodders were adequate to meet the dietary requirements of the dairy buffaloes. Serum phosphorus, copper and selenium were significantly (p<0.001) lower whereas potassium, iron and molybdenum in buffaloes suffering from PHU were significantly (p<0.001) higher than in healthy buffaloes. It was concluded that phosphorous deficient soils play a major role by transferring this deficiency to plants and ultimately reaching to animals where hypophosphataemia is a consistent finding.

Development of a Battery Monitoring Technology using Its Impedance (임피던스를 이용한 배터리 모니터링 기술)

  • Shim, Jae-Hong;Kim, Jae-Dong
    • Journal of the Semiconductor & Display Technology
    • /
    • v.10 no.4
    • /
    • pp.25-29
    • /
    • 2011
  • Emerging demands for rechargeable battery for various applications needs more effective battery management system such as the prediction of the usable time about a battery. Many prediction methods have been suggested but none of them come into bounds of reliability. In this paper, we proposed a new prediction algorithm for the remaining capacity of a rechargeable battery by using the transformed curve based on its impedance. Hardware for monitoring a battery was designed and made. Through a series of experiment, we showed the effectiveness of the proposed prediction algorithm of a battery's remaining capacity.

A Study on the Indoor Environment Evaluation and Improvement of the Atrium in Summer (하계 아트리움 실내환경 평가 및 개선방안에 관한 연구)

  • Nam, Jung-Woo;Kwon, Kyung-Woo;Won, Jong-Seo
    • 한국태양에너지학회:학술대회논문집
    • /
    • 2009.11a
    • /
    • pp.216-221
    • /
    • 2009
  • The purpose of this study is to evaluate and improve the indoor environment of the Atrium in summer. Thermal and daylighting performance was evaluated quantitatively by integrated simulation according to 4 types of shading device.(none shading, opaque shading, translucent shading, internal blind) As a result, with internal blind, the effects of isolating solar radiation and reducing indoor temperature are estimated to be decreased by about 90% and $3.2^{\circ}C$. In the outer shading device which is controled according to solar altitude, the effects of isolating solar radiation and reducing indoor temperature are revealed to be decreased by about 82% and $4.9^{\circ}C$.

  • PDF