• Biomolecules & Therapeutics
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• 제4권3호
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• pp.232-238
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• 1996

The physical dependence potency of DA-5018, a non-narcotic analgesic agent, was tested in mice dosed with 0.5 and 4 mg/kg/day for 2 months and daily increasing doses of 1, 2, 4, 6, 8 and 10 mg/kg over 10 days. Physical dependence was assessed taking natural withdrawal induced morphine-type abstinence (jumping, falling, biting or backward locomotion, rearing etc.) as well as barbiturates-type abstinence (body weight reduction, convulsion, ataxia etc.) into consideration. The results were compared with those after the same daily increasing doses of morphine. DA-5018 did not show evidence of physical dependence liability or abuse potential as measured by morphine-type or barbiturate-type abstinence signs following daily increasing or 2-month repeated administration. On the other hand, daily increasing doses of morphine produced physical dependence and the dependent state disappeared about 6 hours after the start of withdrawal signs. In the single dose suppression test, a single dose of morphine completely suppressed natural withdrawal signs that appeared in morphine-dependent animals. Therefore, these results indicate that DA-5018 does not have abuse potential and physical dependence liability.

• Journal of Magnetics
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• 제21권4호
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• pp.635-643
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• 2016

Improvements were made in the study for the design of the conventional Eddy Current Separator (ECS) used for separating small sized non-ferrous particles in the waste. These improvements include decreasing the air gap between the material and magnetic drum, making the drum position adjustable and placing the splitter closer to the drum. Thus, small particles were separated with high efficiency. The magnetic drum was removed from inside the ECS conveyor belt system as design change and was placed as a separate unit. Hence, the force generated on the test material increased by about 5.5 times while the air gap between the non-ferrous materials and drum decreased from 3 mm to 1 mm. The non-metal material in the waste is separated before the drum in the novel design. Whereas non-ferrous metal particles are separated by falling into the splitter as a result of the force generated as soon as the particles fall on the drum. Every material that passes through the drum can be recycled as a result of moving the splitter closer to the contact point of the drum. In addition, the drum can also be used for the efficient separation of large particles since its position can be adjusted according to the size of the waste material. The performance of the novel design ECS was verified via analytical approaches, finite element analysis (FEA) and experimental studies.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2002년도 추계학술대회 논문집
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• pp.667-670
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• 2002

Uniform metal-droplet deposition using laser is analyzed. Using the variation principle and modeling the semi-solid phase as a non-Netwonian slurry, this model can greatly save the computational expenses that conventional numerical procedures have suffered from. The simulation results revealed that the developed model could reasonably describe the collision behavior of molten metal with solid surface. Simulations were made with variation of the falling distance and time.

• 동의신경정신과학회지
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• 제27권4호
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• pp.207-214
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• 2016

Objectives: This study was conducted to identify the effects of the Qi-gong Exercise program on the physical health status, the fear of falling, balance efficacy, and Hwa-Byung in the elderly. Methods: A non-equivalent control group pretest-posttest design was used in 52 elderly subjects who were assigned to the experimental group and the control group (26 subjects in each group). Study out-comes were measured by structured questionnaires from July 2015 to October 2015. For data analysis, the Chi-square test, the Fisher's exact probability test, the Mann-Whitney U test, the paired t-test, and the Wilcoxon signed rank test were performed using SPSS version 20.0. Results: There were significant differences in the physical health status (Z=12.000, p<.001), balance efficacy (Z=60.500, p=<.001), and Hwa-Byung (Z=20.500, p=<.001) between the two groups in pretest and posttest. Conclusions: The findings confirmed that the Qi-gong Exercise program is effective in improving the physical health status, balance efficacy, and Hwa-Byung in the elderly subjects in the community. It can be recommended as a public health program for the elderly population in the community.

• 한국군사과학기술학회지
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• 제22권6호
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• pp.745-753
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• 2019

Recently, with the development of long-range / high-altitude guided weapon system for defense against ballistic missile, test range and firing altitude for guided weapons are increasing. Due to the increase in the test range and the intercepting altitude, it is expected to increase the range of safety area required for the firing test. Comparing to the foreign countries which have many desert or non-residence, in the domestic circumstances where the population is concentrated and distributed, it is more important to predict the falling area and to set the safety area for safely carry out the long-range / high-altitude intercept test. In this paper, we consider the following three points. The first is the booster fall trajectory modeling, the second is the shroud fall trajectory modeling, and finally, the debris dispersion modeling for the missile intercept. Especially, the AUTODYN model was used to predict debris falling area which produced in the high-speed guided missile intercepting test.

• 대한간호학회지
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• 제45권6호
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• pp.823-833
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• 2015

Purpose: The purpose of the study was to investigate the effects of the Thera-Band exercise program following total knee arthroplasty. Methods: The research design for this study was a nonequivalent control group non-synchronized design. Participants were 30 patients for the experimental group and 30 patients for the control group. The experimental group participated in the Thera-Band exercise program in addition to conventional CPM (continuous passive motion) exercise. The control group received conventional CPM exercise only. Outcome measures were pain, knee flexion range of motion, CRP, and psychological parameters (self-efficacy and fear of falling). Data were analyzed using ${\chi}^2$-test, Fisher's exact test, t-test, and repeated measure ANOVA with SPSS/PC version 21.0. Results: There were significant improvement in self-efficacy, and decreases in pain, and fear of falling in the experimental group compared to the control group. However, no significant differences were found between the two groups for CRP and knee flexion ROM. Conclusion: The Thera-Band exercise program gave an additional benefit over the conventional CPM exercise for patients following total knee arthroplasty, and is recommended for use as an effective nursing intervention for patients after total knee arthroplasty.

• 기본간호학회지
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• 제13권1호
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• pp.60-67
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• 2006

Purpose: To identify the relationship between medication use and falls among hospitalized stroke patients. Method: The medical records of 472 patients with strokes were reviewed using a questionnaire on falling developed by the authors. Frequencies, percentages, means, standard deviations, and t-test and ${\chi}^2$-test, multiple logistic regression analysis were done using the SAS program. Results: The rate for falls by the patients during their stay in the hospital was 14.0%. The length of stay was longer and the morbidity duration of stroke shorter in the fall group than in the non-fall group. The use of sedatives, laxatives, and antidepressants was a significant predictor of falls and was associated with increase likelihood of falling(1.82, 1.81, 1.75 times respectively). Conclusion: In hospitalized stroke patients, there was a significant association between the use of sedatives, laxatives, antidepressants and falls. The number and kinds of ingested drugs was also associated with falls. It is necessary to further analyze the causes of falls based on results of the present study.

• 대한안전경영과학회지
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• 제16권3호
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• pp.55-62
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• 2014

During five years (Year 2009~2013), Total victims of 72 %(81,560 people) and those 50.6 %(1,258 people) of death accident occurs in small scale construction site which operate 2 million USD less construction budget. Especially, falling death accident account for 785 people, in the share of 33.2 %(261 people) death disaster takes due to defect of original cause materials. The major safety issues in small scale work place take place while scaffold installation, disassembling, work-plate improper installation or non-professional skills of workers. Furthermore, labor subcontract systems make small construction site shortage of resources. Those workers regard work-plate as unnecessary and consumables supplies. Because of that most of workers use unsafe workplace in most construction site. Therefore, in order to prevent falling accident occurring in small scale work site, government should organize related regulations such as "Work site safety construction method" and then expands education support, financial aid, and sourcing safety supplies for work plate which offer broad variety experiences. Also, introduce certificate solutions for various work plates to improve safety function such as anchoring type method and anti sliding function.

• 한국콘텐츠학회논문지
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• 제20권4호
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• pp.315-330
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• 2020

WTO설립과 FTA협정의 증가로 관세는 낮아지고 있으나 무역구제조치와 무역기술장벽(TBT), 위생검역(SPS), 통관규제 등의 비관세조치들이 무역장벽이 되어 자유무역을 제한하고 있다. 수출주도 경제성장을 이룬 우리나라는 증가하는 비관세조치들에 대하여 대응방안을 제시하여야 한다. 비관세조치들은 복잡하고 국가마다 적용되는 것이 다르므로 유형별, 산업별, 국가별로 맞춤형 대응방안을 제시하여야한다. 이를 위해 비관세조치DB를 구축하여야한다. 이런 비관세조치들을 수집하고 분석하여 대응방안을 제시하기 위해서는 정부 산하의 전담조직이 반드시 필요하다. 그리고 비관세조치에 대한 상대국 간의 협의 등과 WTO위원회에서 활동이 중요하다. 또한 비관세조치에 관한 역량과 전문성을 가진 전문 인력 양성이 필요하다. 기존의 연구가 각 국가의 비관세조치현황을 토대로 한 연구나 국제기구의 보고서 등을 통하여 분석하였기 때문에 조치유형의 식별과 국가 간 비교분석에 한계가 있었다. 그러므로 본고는 규제의 식별과 국가 간 비교가 가능한 WTO I-TIP의 비관세조치DB를 바탕으로 분석하였다.

• 유기물자원화
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• 제20권4호
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• pp.106-117
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• 2012

건조과정에서 시료의 순환과 낙하이동에 따른 건조효과를 평가하기 위하여 음식물류폐기물 8,000kg을 간접건조방식의 건조기에 투입하고 회전스크류 가동시와 미가동시에 대하여 수분함량, 건조율, 평균입자크기 및 입도분포, 증발수분량 및 건조효율을 비교하였다. 음식물류폐기물의 초기 수분함량은 77.1%로서, 회전스크류 가동시에는 가동 후 5시간 만에 수분함량이 14.4%로 낮아진 반면에 미가동시에는 16시간을 가동시켜도 수분함량 35.6%에 머물고 있어 시료의 순환과 낙하이동이 건조효과 상승에 영향을 미치고 있음을 알 수 있다. 건조시작 후 점성구간 도달 이전에는 입자크기가 증가하면서 수분증발률은 최대치를 보인다. 점성구간에서는 입자크기가 최대치를 나타내나 수분증발률은 급감하기 시작하며, 점성구간 이후에는 입자크기와 수분증발률이 동시에 감소하는 것으로 나타났다. 이는 자유수 증발량과 각 구간에서의 점성차이에 기인한 것으로 여겨진다. 평균 입자크기는 가동 후 지속적으로 증가하여 점성구간인 수분함량 70%-60% 범위에서 최대치를 보인 후 감소하는 경향을 나타내었으나 평균 입자크기의 변화정도는 회전스크류 가동방식에 따라 다르게 나타났다. 또한 회전스크류 가동시 입도분포는 25.0mm에서 0.25mm까지 폭넓게 분포하는 반면에 미가동시에는 25.0mm에서 3.56mm까지 의 좁은 입도분포와 25.0mm이상의 입자크기에 집중되고 있다. 회전스크류 가동으로 건조효율에 미치는 효과를 회전스크류 미가동시와 비교하면 시간당 증발수분량은 364%, DS(Dry Solid)당 증발수분량은 356%나 증가한 것으로 평가되었다.