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Evaluation on the Effect of Whole Body Vibration on EEG Frequency-Fluctuation (인체진동이 뇌파변동리듬에 미치는 영향평가)

  • Min, Byung-Chan;Kim, Hyoung-Wook;Kim, Ji-Kwan
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.30 no.4
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    • pp.71-77
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    • 2007
  • In this study, reactions of central nervous systems working against different conditions of forced frequency and acceleration were measured and analyzed. The experiment are conducted with health men. The steady vibration conditions of forced frequency (0.315m/s2-1.0Hz, 0.315m/s2-10Hz and 10Hz-1.0m/s2) are used and the waves of EEG (Electroencephalogram) are measured. As a result, this paper shows that the ${\alpha}-wave$ of frontal lobe transfers from low to high frequency band under the vibration environment. Additionally, the average frequency of ${\alpha}-wave$ is higher under the vibration than under non-vibration environment. In the case of forced frequency of 1.0Hz-0.315m/s2, the feeling with the vibration are nearly same compared with the non-vibration condition. But in the case of 10Hz-1.0m/s2, uncomfortable feeling increased compared with the non-vibration condition. This study also shows the relationship between fluctuation slop and feeling. From this study, it is found that the effect of vibration on human depends on acceleration characteristics. Highly accelerating vibration is more harmful to human.

Body Size Dietary Behaviors Nutrient Intakes and Weight Control Experience in Korean Adolescent Girls

  • Chang, Kyung-Ja;Kwon, Woo-Jung
    • Journal of Community Nutrition
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    • v.3 no.1
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    • pp.8-13
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    • 2001
  • The purpose of study was to test the hypothesis that three are differences in body size dietary behavior and nutrient intakes of adolescent girls with weight control experience. Cross-sectional survey was carried out with a questionnaire and anthropometric measurements . Subjects were 724 healthy adolescent girls from middle and high schools of urban and rural areas in Inchon and divided into two subgroups with weight control experience. Subjects trying to lose weigh were 25.1% in middle school girls and 47.1% in high school girls. There were significant differences in weight and BMI between weight control experience and non- experienced groups in middle school students. There were significant differences in skipping meals and reason of skipping meals between weigh control experience and non-experience groups which might show that skipping meal was used as a weight loss method among female school students. There was no significant difference in nutrient intakes between weight control experienced and non-experienced groups in middle and high school subjects. these results suggest that nutrition education is necessary for adolescent girls to practice appropriate weigh control strategies including desirable eating habits and adequate intake of nutrients such as energy vitamin A vitamin B$_2$calcium and iron.

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Induction of Apoptosis by Ethyl Acetate Fraction of Astragalus membranaceus in Human Non-small Cell Lung Cancer Cells - Apoptosis Induction by Astragalus membranaceus -

  • Park, Hyun-Ji;Park, Shin-Hyung
    • Journal of Pharmacopuncture
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    • v.21 no.4
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    • pp.268-276
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    • 2018
  • Objectives: The purpose of this study is to investigate the anti-cancer effects of different fractions of Astragalus membranaceus (AM) in human non-small cell lung cancer (NSCLC) cells. Methods: We isolated hexane, ethyl acetate, and butanol fractions from crude ethanol extract of AM. The cell death was examined by MTT assay and trypan blue exclusion assay. Apoptosis was detected by DAPI staining, annexin V-PI double staining and cell cycle analysis. The expression of apoptosis-related proteins and mitogen-activated protein kinases (MAPKs) was examined by western blot. Results: Among various fractions of AM, the ethyl acetate fraction of AM (EAM) showed the strongest cytotoxic effect in NSCLC cells. EAM reduced the cell proliferation in a time- and dose-dependent manner in NSCLC cells. In addition, EAM induced the chromatin condensation, and increased the population of sub-G1 phase and annexin V-positive cells in a time-dependent manner, indicating that EAM induced apoptosis in NSCLC cells. Consistently, EAM enhanced the expression of cleaved caspase-8 and -9, and induced the accumulation of cleaved- poly (ADP-ribose) polymerase (PARP). Among MAPK proteins, only ERK was dephosphorylated by EAM, suggesting that ERK might be related with EAM-induced apoptosis. Conclusion: Our results clearly demonstrate that EAM exhibited anti-cancer effects in NSCLC cells by induction of apoptosis. We provide a valuable evidence which suggests that AM could be a desirable therapeutic option for treatment of NSCLC.

A Study of the Expression of Human Body in Modern Fashion Design - focused on fashion design since 1990- (현대 패션 디자인에 나타난 신체표현 분석에 대한 연구 - 1900년 이후의 패션 디자인을 중심으로 -)

  • 권기영;조현주
    • Journal of the Korean Home Economics Association
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    • v.40 no.7
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    • pp.173-192
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    • 2002
  • This study is intended to observe the meaning, aesthetic formative characteristics of the human body which is introduced and applied to the fashion design. The analysis of the modern fashion design describing the human body refers to the extracted fashion design which expresses the human body appearing in domestic & foreign fashion magazines as well as publications associated with it and published since 1990. The analysis of the way of expression, the image and the design elements in these fashion design works, has had to formative characteristics in each of the three parts. The pursuit of formative characteristics through simplifying the expression of the human body, uprising of anatomical expression, and metaphorical expression with the help of personification and objectification can be thought of as characteristics of expressing pattern. And the op-art, optical illusion by virtue of pointillism, the use of non-woven molding, and action painting technique can be described as expression tools to recognize the human body. Images are presented in the characteristics of being grotesque, humorous, erotic, futuristic and mysterious. The characteristics of designs are expressed in creative detail, trimming, pattern and accessory using the form of human body itself as an item of clothing tends to show the unity of human body and clothing. The human body in the modern era reflects the post human image as well as its meaning as a medium and tool. It is also perceived as a specific object to be self-conscious of in this reality with the loss of humanity, alienation and the confusion of identity. The analysis of the image and way of expression of human body in the fashion design, and the meaning of human body will play an important role of identifying tole viewpoint about human body as well as prospecting what the human being will be in the future.

Performance Evaluation of Attention-inattetion Classifiers using Non-linear Recurrence Pattern and Spectrum Analysis (비선형 반복 패턴과 스펙트럼 분석을 이용한 집중-비집중 분류기의 성능 평가)

  • Lee, Jee-Eun;Yoo, Sun-Kook;Lee, Byung-Chae
    • Science of Emotion and Sensibility
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    • v.16 no.3
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    • pp.409-416
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    • 2013
  • Attention is one of important cognitive functions in human affecting on the selectional concentration of relevant events and ignorance of irrelevant events. The discrimination of attentional and inattentional status is the first step to manage human's attentional capability using computer assisted device. In this paper, we newly combine the non-linear recurrence pattern analysis and spectrum analysis to effectively extract features(total number of 13) from the electroencephalographic signal used in the input to classifiers. The performance of diverse types of attention-inattention classifiers, including supporting vector machine, back-propagation algorithm, linear discrimination, gradient decent, and logistic regression classifiers were evaluated. Among them, the support vector machine classifier shows the best performance with the classification accuracy of 81 %. The use of spectral band feature set alone(accuracy of 76 %) shows better performance than that of non-linear recurrence pattern feature set alone(accuracy of 67 %). The support vector machine classifier with hybrid combination of non-linear and spectral analysis can be used in later designing attention-related devices.

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Contact-Independent Cell Death of Human Microglial Cells due to Pathogenic Naegleria fowleri Trophozoites

  • Kim, Jong-Hyun;Kim, Dae-Sik;Shin, Ho-Joon
    • Parasites, Hosts and Diseases
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    • v.46 no.4
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    • pp.217-221
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    • 2008
  • Free-living Naegleria fowleri leads to a fatal infection known as primary amebic meningoencephalitis in humans. Previously, the target cell death could be induced by phagocytic activity of N. fowleri as a contact-dependent mechanism. However, in this study we investigated the target cell death under a non-contact system using a tissue-culture insert. The human microglial cells, U87MG cells, co-cultured with N. fowleri trophozoites for 30 min in a non-contact system showed morphological changes such as the cell membrane destruction and a reduction in the number. By fluorescence-activated cell sorter (FACS) analysis, U87MG cells co-cultured with N. fowleri trophozoites in a non-contact system showed a significant increase of apoptotic cells (16%) in comparison with that of the control or N. fowleri lysate. When U87MG cells were co-cultured with N. fowleri trophozoites in a non-contact system for 30 min, 2 hr, and 4 hr, the cytotoxicity of amebae against target cells was 40.5, 44.2, and 45.6%, respectively. By contrast, the cytotoxicity of non-pathogenic N. gruberi trophozoites was 10.2, 12.4, and 13.2%, respectively. These results suggest that the molecules released from N. fowleri in a contact-independent manner as well as phagocytosis in a contact-dependent manner may induce the host cell death.

The Effect of Acupuncture at PC7(Daereung) on EEG in Normal Human Subject (대릉(大陵)(PC7) 침자가 뇌파에 미치는 영향)

  • Park, Cheol-Jin;Lee, Sang-Ryong
    • Korean Journal of Acupuncture
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    • v.27 no.2
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    • pp.141-157
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    • 2010
  • Objectives : The aim of this study is to examine the effects of acupuncture at PC7(Daereung) on normal human EEG using power spectral analysis. Methods : EEG power spectrum exhibits site-specific and state-related differences in specific frequency bands. In this study, power spectrum was used as a measure of complexity. 30 subjects (16 males and 14 females; averaged age = 23.4 years) were engaged with thirty channel EEG study. Results : In $\alpha$(alpha) band, the power values at Fp1, Fp2, F7, F8 channels(p<0.05) during PC7 treatment were significantly decreased. But, the power values at Fz channel(p<0.05) during non-acupoint treatment was significantly decreased. In $\beta$(beta) band, the power values at Fp1, Fp2 channels(p<0.05) during PC7 treatment were significantly decreased. But, the power values at Fz channel(p<0.05) during non-acupoint treatment was significantly decreased and at F8, TCP2 channels(p<0.05) during non-acupoint treatment were increased. In $\theta$(theta) band, the power values at Fp1, Fp2, F7, F8 channels(p<0.05) during PC7 treatment were significantly decreased. But, the power values at Fz channel(p<0.05) during non-acupoint treatment was significantly decreased. In $\delta$(delta) band, the power values at Fp1, Fp2, F7, Fz, F8 channels (p<0.05) during PC7 treatment were significantly decreased. But, the power values at Fz channel (p<0.05) during non-acupoint treatment was significantly decreased. $\alpha/\beta$ values during PC7 treatment were decreased. $\beta/\theta$ values during PC7 treatment were decreased. Conclusion : These results suggest that acupuncture at PC7 induce the change on $\alpha$(alpha), $\beta$(beta), $\theta$ (theta), $\delta$(delta) wave values being decreased and and bothe $\alpha/\beta$ and $\beta/\theta$ values being decreased respectively. This is considered that acupuncture at PC7 affects the activity of cerebral cortex and endocrine system.

Frequency of Red Blood Cell Antigens According to Parent Ethnicity in Korea Using Molecular Typing

  • Shin, Kyung-Hwa;Lee, Hyun-Ji;Kim, Hyung-Hoi;Hong, Yun Ji;Park, Kyoung Un;Kim, Min Ju;Kwon, Jeong-Ran;Choi, Young-Sil;Kim, Jun Nyun
    • Annals of Laboratory Medicine
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    • v.38 no.6
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    • pp.599-603
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    • 2018
  • Frequencies of red blood cell (RBC) blood group antigens differ by ethnicity. Since the number of immigrants is increasing in Korea, RBC antigens should be assessed in children/youths with parents of different ethnicities to ensure safe transfusions. We investigated the frequency of RBC antigens, except for ABO and RhD, in 382 children and youths with parents having Korean and non-Korean ethnicities. Subjects were divided into those with ethnically Korean parents (Korean group; N=252) and those with at least one parent of non-Korean ethnicity (non-Korean group; N=130). The 37 RBC antigens were genotyped using the ID CORE XT system (Progenika Biopharma-Grifols, Bizkaia, Spain). The frequencies of the Rh (E, C, e, $hr^S$, and $hr^B$), Duffy ($Fy^a$), MNS ($Mi^a$), and Cartwright ($Yt^b$) antigens differed significantly between the two groups. Eight and 11 subjects in the Korean and non-Korean groups, respectively, exhibited negative expression of high-frequency antigens, whereas 14 subjects in the non-Korean group showed positive expression of low-frequency antigens. The frequency of RBC antigens has altered alongside demographic changes in Korea and might lead to changes in distribution of RBC antibodies that cause acute or delayed hemolytic transfusion reaction.