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Mediastinal Tumors (Report of 29 cases) (종격동종양 29 치험예)

  • 김정석
    • Journal of Chest Surgery
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    • v.1 no.1
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    • pp.37-44
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    • 1968
  • This paper is a review of 29 cases of mediastinal tumors originating in the mediastinum or metastasized from other organs and classified on the basis of histopathological types and specific anatomic location in this depart-ment, during nine years period from January 1959 to December 1967. In twenty-three cases, diagnosis was confirmed by histological findings and the rest of the cases were considered to be mediastinal tumors by clinical and/or roentgenological findings. In this series, metastatic mediastinal carcinomas of unknown primary site were most frequent [30.4%] and lymphoma ranked second in frequency comprising 21.7% of total. Range of age was 5 to 61 years and average mean age was 39 years old. Sex ratio was 1.4 male to female. Subjective complaints in order of frequency were as follows: dyspnea [37%], cough [34%], chest pain[24%] and chest discomfort [21%]. Objective signs were as follows: hoarseness [17%], palpable cervical lymph node[17%], blood tinged sputum [10%], weight loss [10%] and superior vena cava syndrome [7%]. There was no operative mortality. There were histologically nine different kinds of mediasfinal tumors in this series.

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Simplified finite element modelling of non uniform tall building structures comprising wall and frame assemblies including P-Δ effects

  • Belhadj, Abdesselem Hichem;Meftah, Sid Ahmed
    • Earthquakes and Structures
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    • v.8 no.1
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    • pp.253-273
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    • 2015
  • The current investigation has been conducted to examine the effect of gravity loads on the seismic responses of the doubly asymmetric, three-dimensional structures comprising walls and frames. The proposed model includes the P-${\Delta}$ effects induced by the building weight. Based on the variational approach, a 3D finite element with two nodes and six DOF per node including P-${\Delta}$ effects is formulated. Dynamic and static governing equations are derived for dynamic and buckling analyzes of buildings braced by wall-frame systems. The influences of P-${\Delta}$ effects and height of the building on tip displacements under Hachinohe earthquake record are investigated through many structural examples.

Mucin in cancer: a stealth cloak for cancer cells

  • Wi, Dong-Han;Cha, Jong-Ho;Jung, Youn-Sang
    • BMB Reports
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    • v.54 no.7
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    • pp.344-355
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    • 2021
  • Mucins are high molecular-weight epithelial glycoproteins and are implicated in many physiological processes, including epithelial cell protection, signaling transduction, and tissue homeostasis. Abnormality of mucus expression and structure contributes to biological properties related to human cancer progression. Tumor growth sites induce inhospitable conditions. Many kinds of research suggest that mucins provide a microenvironment to avoid hypoxia, acidic, and other biological conditions that promote cancer progression. Given that the mucus layer captures growth factors or cytokines, we propose that mucin helps to ameliorate inhospitable conditions in tumor-growing sites. Additionally, the composition and structure of mucins enable them to mimic the surface of normal epithelial cells, allowing tumor cells to escape from immune surveillance. Indeed, human cancers such as mucinous carcinoma, show a higher incidence of invasion to adjacent organs and lymph node metastasis than do non-mucinous carcinoma. In this mini-review, we discuss how mucin provides a tumor-friendly environment and contributes to increased cancer malignancy in mucinous carcinoma.

Disease related Gene Identification Using Literature and Google data (텍스트마이닝 기법과 구글데이터를 이용한 질병관련 유전자 식별)

  • Kim, Jeong-U;Kim, Hyeon-Jin;Park, Sang-Hyeon
    • Proceedings of the Korea Information Processing Society Conference
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    • 2013.11a
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    • pp.1084-1087
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    • 2013
  • 텍스트마이닝은(Text mining) 바이오분야에서 사용되는 도구 중 하나이다. 본 논문에서는 전립선암(Prostate cancer)과 관련된 질병 유전자(Disease gene)를 찾기 위해 텍스트마이닝을 이용하여 유전자 네트워크(Gene-network)를 구축하였다. 추가적으로 구글(Google) 검색을 통해 네트워크 내의 유전자 노드(Node)들 사이의 간선(Edge)에 새로운 가중치(Weight)를 추가하고 네트워크를 재구성하였다. 구축된 네트워크에서 노드와 노드 사이의 가중치를 기반으로 전립선암과 관련된 질병 유전자를 추출하였다. 본 논문의 방법은 성공적으로 네트워크를 구축하고 질병 유전자를 찾았으며, 구글 데이터를 사용하지 않고 네트워크를 구축하는 경우보다 더 높은 정확성을 입증했다.

A Federated Multi-Task Learning Model Based on Adaptive Distributed Data Latent Correlation Analysis

  • Wu, Shengbin;Wang, Yibai
    • Journal of Information Processing Systems
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    • v.17 no.3
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    • pp.441-452
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    • 2021
  • Federated learning provides an efficient integrated model for distributed data, allowing the local training of different data. Meanwhile, the goal of multi-task learning is to simultaneously establish models for multiple related tasks, and to obtain the underlying main structure. However, traditional federated multi-task learning models not only have strict requirements for the data distribution, but also demand large amounts of calculation and have slow convergence, which hindered their promotion in many fields. In our work, we apply the rank constraint on weight vectors of the multi-task learning model to adaptively adjust the task's similarity learning, according to the distribution of federal node data. The proposed model has a general framework for solving optimal solutions, which can be used to deal with various data types. Experiments show that our model has achieved the best results in different dataset. Notably, our model can still obtain stable results in datasets with large distribution differences. In addition, compared with traditional federated multi-task learning models, our algorithm is able to converge on a local optimal solution within limited training iterations.

Pseudomyogenic Hemangioendothelioma Involving the Esophagus: A Case Report

  • Diab, Abdul-Rahman Fadi;Daradkeh, Salam Saleh;Hassouneh, Alaa Mohammed;Alabbadi, Ali Mousa
    • Journal of Chest Surgery
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    • v.54 no.6
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    • pp.524-527
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    • 2021
  • Herein, we describe the case of a 20-year-old woman who presented with dysphagia of 2 months' duration associated with vomiting, moderate abdominal pain, decreased oral intake, and significant weight loss. During the past 3 years, the patient experienced intermittent mild abdominal pain with infrequent vomiting. Endoscopy at Jordan University Hospital showed a mass in the esophagus, and endoscopic biopsies were performed. The preliminary histopathological report excluded malignancy. Two days after endoscopy, the patient presented to the emergency department complaining of severely worsening pain and total dysphagia. The pain persisted despite intravenous paracetamol administration, which was concerning for esophageal perforation; therefore, an urgent surgical intervention was performed. The mass was removed surgically, along with a para-esophageal lymph node. The final histopathological results of the endoscopic and resected specimens supported the diagnosis of pseudomyogenic hemangioendothelioma (PMHE). This is the first case reporting esophageal involvement of PMHE.

Static and harmonic analysis of moderately thick square sandwich plate using FEM

  • Manoj Nawariya;Avadesh K. Sharma;Pankaj Sonia;Vijay Verma
    • Advances in materials Research
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    • v.12 no.2
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    • pp.83-100
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    • 2023
  • In this paper, sandwich plate, constructed with orthotropic and isotropic composite materials, is analyzed to obtain the static and harmonic behavior. The analysis is done by using ANSYS APDL FEM tool. A solid-shell 190 and an 8-node solid 185 elements are employed for face and core material respectively to analyze the plate. Results was attained by using Reissner-Mindlin theory. Effect of increasing thickness ratio of face sheet to depth of the plate is presented on static, vibration and harmonic response on the sheet and the results are discussed briefly. Published work in open domain was used to validate the results and observed excellent agreement. It can be stated that proposed model presents results with remarkable accuracy. Results are obtained to reduce the weight of the plate and minimizing the vibration amplitudes.

Illumination correction via improved grey wolf optimizer for regularized random vector functional link network

  • Xiaochun Zhang;Zhiyu Zhou
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.17 no.3
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    • pp.816-839
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    • 2023
  • In a random vector functional link (RVFL) network, shortcomings such as local optimal stagnation and decreased convergence performance cause a reduction in the accuracy of illumination correction by only inputting the weights and biases of hidden neurons. In this study, we proposed an improved regularized random vector functional link (RRVFL) network algorithm with an optimized grey wolf optimizer (GWO). Herein, we first proposed the moth-flame optimization (MFO) algorithm to provide a set of excellent initial populations to improve the convergence rate of GWO. Thereafter, the MFO-GWO algorithm simultaneously optimized the input feature, input weight, hidden node and bias of RRVFL, thereby avoiding local optimal stagnation. Finally, the MFO-GWO-RRVFL algorithm was applied to ameliorate the performance of illumination correction of various test images. The experimental results revealed that the MFO-GWO-RRVFL algorithm was stable, compatible, and exhibited a fast convergence rate.

Characteristics of Sweet Sorghum Germplasm for Bioethanol Production in Reclaimed Soil (간척지 토양에서 바이오에탄올용 단수수 유전자원의 생육특성)

  • Choi, Yong-Hwan;Moon, Youn-Ho;Ahn, Seung-Hyun;Yoon, Young-Mi;Cha, Young-Lok;Koo, Bon-Cheol;Park, Kwang-Geun;Han, Hee-Suk;Kim, Wan-Seok
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.57 no.4
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    • pp.384-388
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    • 2012
  • Variation of major characteristics of 140 sweet sorghum germplasm which had been collected from domestic and foreign countries were investigated to study the possibility of bioethanol production in reclamed soil of Korea. Averages of culm length, ear length, the number of nodes, stem diameter, fresh weight yield, and growth duration from seeding to heading were 175 cm, 26 cm, 9, 11.6 mm, 12.1 t/ha, and 96 days, respectively. Sugar content, which has a great effect on bioethanol, ranged from 5.7 to 23.5 Brix (average 14.1 Brix). Sugar contents of selected two varieties were more than 20 Brix. Fresh weight yield ranged from 20 to 50 t/ha (average 12.1 t/ha). Fresh weight yield of selected three varieties were more than 30 t/ha. Culm length showed highly significant positive correlation with the ear length, the number of nodes, stem diameter, fresh weight yield, and growth duration from seeding to heading. The number of node showed highly significant positive correlation with stem diameter and fresh weight yield. Fresh weight yield showed highly significant positive correlation with culm length, the number of nodes, stem diameter, and growth duration from seeding to heading.

Review of Transverse Steel Design in Continuously Reinforced Concrete Pavement through Finite Element Analysis (유한요소해석을 이용한 연속철근콘크리트 포장의 횡방향 철근 설계 검토)

  • Choi, Pangil;Ha, Soojun;Chon, Beom Jun;Kil, Yong Su;Won, Moon-Cheol
    • International Journal of Highway Engineering
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    • v.16 no.2
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    • pp.25-34
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    • 2014
  • PURPOSES : This paper numerically evaluates the contribution of transverse steel to the structural behavior of continuously reinforced concrete pavements to understand the role of transverse steel. METHODS : Two-lane continuously reinforced concrete pavements with and without transverse steel were analyzed through finite element analysis with the aid of commercial finite element analysis program DIANA; the difference in their structural behavior such as deflection, joint opening, and stress distribution was then evaluated. Twenty-node brick elements and three-node beam elements were used to model concrete and steel, respectively. Sub-layers were modeled with horizontal and vertical tensionless spring elements. The interactions between steel and surrounding concrete were considered by connecting their nodes with three orthogonal spring elements. Both wheel loading and environmental loading in addition to self-weight were considered. RESULTS : The use of transverse steel in continuously reinforced concrete pavements does not have significant effects on the structural behavior. The surface deflections change very little with the use of transverse steel. The joint opening decreases when transverse steel is used but the reduction is quite small. The transverse concrete stress, rather, increases when transverse steel is used due to the restraint exerted by the steel but the increase is quite small as well. CONCLUSIONS : The main role of transverse steel in continuously reinforced concrete pavements is supporting longitudinal steel and/or controlling unexpected longitudinal cracks rather than enhancing the structural capacity.