• 제목/요약/키워드: no-failure

검색결과 2,586건 처리시간 0.034초

조기(TNM Stage I & II) 구강 편평세포암종의 초치료 실패 (The Failure of Initial Treatment for TNM Stage I & II Squamous Cell Carcinomas of the Oral Cavity)

  • 이현석;정한신;김태욱;손영익;백정환
    • 대한두경부종양학회지
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    • 제21권1호
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    • pp.26-31
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    • 2005
  • Backgrounds and Objectives: Squamous cell carcinomas of the oral cavity(SCOC) in TNM stage I & II have relatively high chance to be cured compared to those in the advanced stage, but sometimes result in the treatment failure with poor prognosis. There have been few reports on the patterns of failure and the clinical courses for SCOC in stage I & II after the failure of initial treatment. This study is directed at identifying the clinical outcomes of stage I & II SCOC and the salvage rate after initial treatment and suggesting an optimal level of treatment by analyzing the patterns of failure. Material and Methods: The medical records of 36 patients with SCOC, initially diagnosed between 1995 and 2001 as TNM stage I & II were reviewed retrospectively. The patterns of failure, salvage treatment, clinical courses, and the survival of these subjects were analyzed. The minimum follow-up period of no-evidence of disease(NED) was 12 months with an average of 32.2 months. Results: Overall rate of the treatment failure in SCOC of stage I & II was 41. 7%(15/36 cases). Most of the treatment failure in the subjects with stage I tumors occurred in regional lymph node. Local failure was the most frequent form of failure in the subjects with stage II tumors after wide excision of primary tumor with elective neck dissection and/or radiation therapy. No significant correlation was noted between the safety margin and the local failure. Elective neck dissections in stage I & II SCOC had a tendency to reduce regional failure (p=0.055). The salvage rates at 24 months were 85.7% in stage I, and 37.5% in stage II. The 3-year survival rate after the failure of initial treatment was 55.0%. Conclusion: SCOC of stage I & II after the failure of initial treatment showed poor prognosis despite of the salvage treatments. This study implies that the elective neck dissections for regional lymph node should be required for SCOC of stage I & II to reduce the treatment failure.

철근 콘크리트의 뚫림전단 파괴메카니즘에 과한 비교 (Comparison on the Failure Mechanism of Punching Shear in the Reinforced Concrete)

  • 이주나;연규원;이호준;박찬수
    • 한국콘크리트학회:학술대회논문집
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    • 한국콘크리트학회 2000년도 봄 학술발표회 논문집
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    • pp.533-538
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    • 2000
  • In R.C. flat slab system, a brittle punching failure is a very fatal problem. But there is no generally well-defined answer to the problem and there are wide differences in current practical design codes. therefore, in this study, the factors affecting to punching failure mechanism have been studied to find out the punching shear behavior in R.C. flat slabs by comparing other investigations and practical design codes. Therefore, In this study, the factors affecting to punching failure mechanism have been studied to find out the punching shear behavior in R.C. flat slabs by comparing other investigations and practical design codes. The conclusions in this study are summarized as follows; 1) The factors affecting to punching shear are concrete strength ($f_\alpha$), ratio of column side length to slab depth (c/d), ratio of distance from column center to radial contraflexure (l/d), yield strength of steel ($f_y$), flexural reinforcement ratio ($\rho$) and size effects. 2) It is shown that th use of $\surd{f_{ck}}$in applying($f_\alpha$ to punching shear strength estimation may be more sensitive in high concrete strength. 3) The effects of l/d, ($f_y$, size are no clear in the punching failure mechanism, so in the future, it should be investigated with the effects of various composed load.

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Instrumentation Failure after Partial Corpectomy with Instrumentation of a Metastatic Spine

  • Park, Sung Bae;Kim, Ki Jeong;Han, Sanghyun;Oh, Sohee;Kim, Chi Heon;Chung, Chun Kee
    • Journal of Korean Neurosurgical Society
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    • 제61권3호
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    • pp.415-423
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    • 2018
  • Objective : To identify the perioperative factors associated with instrument failure in patients undergoing a partial corpectomy with instrumentation (PCI) for spinal metastasis. Methods : We assessed the one hundred twenty-four patients with who underwent PCI for a metastatic spine from 1987 to 2011. Outcome measure was the risk factor related to implantation failure. The preoperative factors analyzed were age, sex, ambulation, American Spinal Injury Association grade, bone mineral density, use of steroid, primary tumor site, number of vertebrae with metastasis, extra-bone metastasis, preoperative adjuvant chemotherapy, and preoperative spinal radiotherapy. The intraoperative factors were the number of fixed vertebrae, fixation in osteolytic vertebrae, bone grafting, and type of surgical approach. The postoperative factors included postoperative adjuvant chemotherapy and spinal radiotherapy. This study was supported by the National Research Foundation grant funded by government. There were no study-specific biases related to conflicts of interest. Results : There were 15 instrumentation failures (15/124, 12.1%). Preoperative ambulatory status and primary tumor site were not significantly related to the development of implant failure. There were no significant associations between insertion of a bone graft into the partial corpectomy site and instrumentation failure. The preoperative and operative factors analyzed were not significantly related to instrumentation failure. In univariable and multivariable analyses, postoperative spinal radiotherapy was the only significant variable related to instrumentation failure (p=0.049 and 0.050, respectively). Conclusion : When performing PCI in patients with spinal metastasis followed by postoperative spinal radiotherapy, the surgeon may consider the possibility of instrumentation failure and find other strategies for augmentation than the use of a bone graft for fusion.

독립현가형 AWD 차량의 구동축 가속 수명 평가에 관한 연구 (A Study on the Accelerated Life Evaluation of Drive Shaft for Independent Suspension type AWD Vehicle)

  • 김도식
    • 한국신뢰성학회지:신뢰성응용연구
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    • 제11권4호
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    • pp.343-356
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    • 2011
  • This paper proposes an accelerated life evaluation of drive shaft. The life test of drive shaft for independent suspension type AWD vehicle should be performed by use of the least test sample because many number of samples can't be used for the test because of its mass capacity and high price. We calculated the no failure test time by application of no failure test concept, and the already performed test data for drive shaft are applied for some kinds of reliability coefficients which are needed for calculation of life test time. And, for analysis of real driving condition of vehicle, the load spectrum is prepared using the needed road condition and vehicle data. The inverse power model is used for accelerated life test. The equivalent torque of load spectrum is achieved by use of Miner's Rule, and then the final accelerating condition is determined by decision of the accelerated test torque. This paper shows that the accelerated life test results corresponds with the target life and the proposed life test method can be very well applied to no failure life test for mass capacity machinery components.

Strength failure behavior of granite containing two holes under Brazilian test

  • Huang, Yan-Hua;Yang, Sheng-Qi;Zhang, Chun-Shun
    • Geomechanics and Engineering
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    • 제12권6호
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    • pp.919-933
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    • 2017
  • A series of Brazilian tests under diameter compression for disc specimens was carried out to investigate the strength and failure behavior by using acoustic emission (AE) and photography monitoring technique. On the basis of experimental results, load-displacement curves, AE counts, real-time crack evolution process, failure modes and strength property of granite specimens containing two pre-existing holes were analyzed in detail. Two typical types of load-displacement curves are identified, i.e., sudden instability (type I) and progressive failure (type II). In accordance with the two types of load-displacement curves, the AE events also have different responses. The present experiments on disc specimens containing two pre-existing holes under Brazilian test reveal four distinct failure modes, including diametrical splitting failure mode (mode I), one crack coalescence failure mode (mode II), two crack coalescences failure mode (mode III) and no crack coalescence failure mode (mode IV). Compared with intact granite specimen, the disc specimen containing two holes fails with lower strength, which is closely related to the bridge angle. The failure strength of pre-holed specimen first decreases and then increases with the bridge angle. Finally, a preliminary interpretation was proposed to explain the strength evolution law of granite specimen containing two holes based on the microscopic observation of fracture plane.

파손확률 모델을 이용한 솔더 조인트의 건전성 평가 (Reliability Estimation of Solder Joint by Using Failure Probability Model)

  • 명노훈;이억섭;김동혁
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2004년도 춘계학술대회
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    • pp.365-370
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    • 2004
  • Generally, component and FR-4 board are connected by solder joint. Because material properties of components and FR-4 board are different, component and FR-4 board show different coefficients of thermal expansion (CTE) and thus strains in component and board are different when they are heated. That is, the differences in CTE of component and FR-4 board cause the dissimilarity in shear strain and solder joint' failure. The first order Taylor series expansion of the limit state function incorporating with Tresca failure criterion is used in order to estimate the failure probability of solder joints under heated condition. Using shear stresses and shear strains appeared on the solder joint, we estimate the failure probability of solder joints with the Tresca failure criterion. The effects of random variables such as CTE, distance of the solder joint from the neutral point(DNP), temperature variation and height of solder on the failure probability of the solder joint are systematically studied by using the failure probability model with first order reliability method(FORM).

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신뢰도 평가를 위한 배전계통 설비기기 고장률 분석 (Power Distribution System Equipment Failure Rate Analysis for Reliability Estimation)

  • 이희태;김재철;문종필;박창호
    • 한국조명전기설비학회:학술대회논문집
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    • 한국조명전기설비학회 2004년도 춘계학술대회 논문집
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    • pp.370-373
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    • 2004
  • The inside and outside of the country utilities considered that they focused energy and economic aspect for short-term in new environment change of restructure. but it need service reliability preservation and improvement countermeasure, that is no to use existent estimation method for reliability preservation. therefore, analyze the equipment failure rate for suitable reliability preservation through equipment failure rate analysis of power distribution r system and evaluated equipment that is composing power distribution system by the failure rate. This paper estimated failure causes and the TVFR(Time Varying Failure Rate) for main equipment that is composing power distribution system using Weibull distribution.

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Roof collapse of shallow tunnel in layered Hoek-Brown rock media

  • Yang, X.L.;Li, K.F.
    • Geomechanics and Engineering
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    • 제11권6호
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    • pp.867-877
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    • 2016
  • Collapse shape of tunnel roof in layered Hoek-Brown rock media is investigated within the framework of upper bound theorem. The traditional collapse mechanism for homogeneous stratum is no longer suitable for the present analysis of roof stability, and it would be necessary to propose a curve failure mode to describe the velocity discontinuity surface in layered media. What is discussed in the paper is that the failure mechanism of tunnel roofs, consisting of two different functions, is proposed for layered rock media. Then it is employed to investigate the impending roof failure. Based on the nonlinear Hoek-Brown failure criterion, the collapse volume of roof blocks are derived with the upper bound theorem and variational principle. Numerical calculations and parametric analysis are carried out to illustrate the effects of different parameters on the shape of failure mechanism, which is of overriding significance to the stability analysis of tunnel roof in layered rock media.

Characteristics of failure surfaces induced by embankments on soft ground

  • Hong, Eun-Soo;Song, Ki-Il;Yoon, Yeo-Won;Hu, Jong-Wan
    • Geomechanics and Engineering
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    • 제6권1호
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    • pp.17-31
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    • 2014
  • This paper investigates the development of failure surfaces induced by an embankment on soft marine clay deposits and the characteristics of such surfaces through numerical simulations and its comparative study with monitoring results. It is well known that the factor of safety of embankment slopes is closely related to the vertical loading, including the height of the embankment. That is, an increase in the embankment height reduces the factor of safety. However, few studies have examined the relationship between the lateral movement of soft soil beneath the embankment and the factor of safety. In addition, no study has investigated the distribution of the pore pressure coefficient B value along the failure surface. This paper conducts a continuum analysis using finite difference methods to characterize the development of failure surfaces during embankment construction on soft marine clay deposits. The results of the continuum analysis for failure surfaces, stress, displacement, and the factor of safety can be used for the management of embankment construction. In failure mechanism, it has been validated that a large shear displacement causes change of stress and pore pressure along the failure surface. In addition, the pore pressure coefficient B value decreases along the failure surface as the embankment height increases. This means that the rate of change in stress is higher than that in pore pressure.

The Determinants of Potential Failure of Islamic Peer-to-Peer Lending: Perceptions of Stakeholders in Indonesia

  • MUHAMMAD, Rifqi;FAKHRUNNAS, Faaza;HANUN, Amalia Khairina
    • The Journal of Asian Finance, Economics and Business
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    • 제8권2호
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    • pp.981-992
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    • 2021
  • This study identifies the determinants of potential failure of Islamic Peer-to-Peer (P2P) lending in Indonesia, and the mediating effect of Islamic ethics on reducing the potential for failure of Islamic P2P lending. This study uses primary data retrieved through questionnaires from the perspective of 152 stakeholders in Islamic P2P lending. Using a structural equation model (SEM), the study found that indebtedness, financing size, and governance have positive and significant relationships with the potential failure of Islamic P2P lending. This study provides evidence that the customer's internal conditions and the governance structure applied can increase the potential failure of Islamic P2P lending. Further, Islamic ethics is evidently able to partially reduce the potential failure of Islamic P2P lending by lessening risk management exposure, but it fails to address failure through Ponzi scheme exposure. As an implication, this study suggest that Islamic P2P lending must implement Islamic ethics more comprehensively by optimizing the advisory and supervisory role of the shariah board within their overall boards of directors also in their operational activities. Finally, it also adds to the existing knowledge on financial technology literature, particularly on the determinants of potential failure of financial technology from the perspective of stakeholders.