• Genomics & Informatics
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• v.10 no.1
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• pp.33-39
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• 2012

High-throughput genomic technologies (HGTs), including next-generation DNA sequencing (NGS), microarray, and serial analysis of gene expression (SAGE), have become effective experimental tools for cancer genomics to identify cancer-associated somatic genomic alterations and genes. The main hurdle in cancer genomics is to identify the real causative mutations or genes out of many candidates from an HGT-based cancer genomic analysis. One useful approach is to refer to known cancer genes and associated information. The list of known cancer genes can be used to determine candidates of cancer driver mutations, while cancer gene-related information, including gene expression, protein-protein interaction, and pathways, can be useful for scoring novel candidates. Some cancer gene or mutation databases exist for this purpose, but few specialized tools exist for an automated analysis of a long gene list from an HGT-based cancer genomic analysis. This report presents a new web-accessible bioinformatic tool, called CaGe, a cancer genome annotation system for the assessment of candidates of cancer genes from HGT-based cancer genomics. The tool provides users with information on cancer-related genes, mutations, pathways, and associated annotations through annotation and browsing functions. With this tool, researchers can classify their candidate genes from cancer genome studies into either previously reported or novel categories of cancer genes and gain insight into underlying carcinogenic mechanisms through a pathway analysis. We show the usefulness of CaGe by assessing its performance in annotating somatic mutations from a published small cell lung cancer study.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.39C no.3
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• pp.209-222
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• 2014

NCW is a new operational concept for modern warfare to improve the ability to conduct combat by connecting command and control system via network. To realize NCW integrating information sharing system between multiple platforms, CDL is considered as a key component for high-speed transmission of ISR data. Accordingly, further studies to enhance the performance of CDL are being performed around the world, and our government has also developed self-reliant CDL, MPI-CDL. However, the maximum data rate and networking performance of current CDL still fall short of the objective to enable multiple systems to share the large ISR data. Therefore, in this paper, we analyze the development flow and international technical trends of CDL, and present an approach for enhancing data rate and networking capacity of the next generation CDL.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.32 no.2
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• pp.201-211
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• 2022

According to the recent change in the cybersecurity paradigm, research on anomaly detection methods using machine learning and deep learning techniques, which are AI implementation technologies, is increasing. In this study, a comparative study on data preprocessing techniques that can improve the anomaly detection performance of a GRU (Gated Recurrent Unit) neural network-based intrusion detection model using NGIDS-DS (Next Generation IDS Dataset), an open dataset, was conducted. In addition, in order to solve the class imbalance problem according to the ratio of normal data and attack data, the detection performance according to the oversampling ratio was compared and analyzed using the oversampling technique applied with DCGAN (Deep Convolutional Generative Adversarial Networks). As a result of the experiment, the method preprocessed using the Doc2Vec algorithm for system call feature and process execution path feature showed good performance, and in the case of oversampling performance, when DCGAN was used, improved detection performance was shown.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2011.05a
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• pp.668-670
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• 2011

The Next-generation IT technology has been evolving from single technique to another which has merged, converging characteristics. The government categorized the 5 essential technologies to secure competitiveness in designing system semiconductors as smart motor vehicle info-tainment platform, smart TV multimedia system, smart phone analog interface technique, smart convergence digital communication and RF techniques, and advanced power management for smart devices. Also, it designated smart phone, smart TV, smart motor vehicle, and smart pad as the key industries. Such core techniques will become the key technologies of semiconductor design to secure the competitiveness of the next generation smart devices and the techniques can be transferred to fab-less design companies. In this contribution, we analyze the issues and the problems of the smart phone analog and interface techniques.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.38C no.5
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• pp.440-451
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• 2013

Recently, researches of technology and standardization for maritime safety are proceeding internationally. In particular, some technologies and strategies for e-Navigation have been developed and the necessity of development of next generation VTS (Vessel Traffic Service) has been raised in Korea. In order to construct user oriented VTS system for domestic environment, VTS operators are asked for their requirements related to developing VTS and the opinions should be reflected in the VTS. So in this paper, we collect the requirements from fifteen VTS centers in the country and we also analyze them. Furthermore, we propose an ASM (Application Specific Messages) service, which was not supported by current VTS, and we verify the proposed ASM through AIS (Automatic Identification System) system and simulation terminal for maritime safety.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.5 no.4
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• pp.668-675
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• 2001

Recently, the performance of the commercial PCS(Personal Communication Service) system has been improved to the uppermost limit and ultimately the next generation mobile communication is to be realized by IMT-2000 (International Mobile Communication-2000) to provide multimedia services. Therefore, the new type receiving system is researched actively and one of the most important part in a receiver is direct conversion method. The direct conversion method is suitable for low power consumption, small size, MMIC, and low price, which is to be adopted to the next generation mobile communication systems. In this case, however, several problems occur due to DC-offset. The DC-offset suppresses amplification of the required signal because of the leakage signal of frequency synthesizer in the system. In this thesis, the removing method of DC-offset was considered. There are four removing techniques of DC-offset, which are AC-coupling, large capacitor, DC-feedback loop, and DC-free coding. Among these, the AC-coupling method is the most simplest method and the DC-feedback loop method has the best performance. Then, the performance of the AC-coupling method and DC-feedback loop method are evaluated by HP's ADS simulation tool. As a result, the AC-coupling method cannot be used to the digital communication systems due to data loss. On the other hand, it was confirmed that the DC-feedback loop method is suitable for the direct conversion receiver.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.17 no.12
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• pp.3009-3015
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• 2013

Next-generation sequencing (NGS) has enabled whole genome and transcriptome single nucleotide variant (SNV) discovery in cancer and method of the most fundamental being determining an individual's genotype from multiple aligned short read sequences at a position. Bayesian algorithm estimate parameter using posterior genotype probabilities and other method, EM algorithm, estimate parameter using maximum likelihood estimate method in observed data. Here, we propose a novel genotype-calling system and compare and analyze the effect of sample size(S = 50, 100 and 500) on posterior estimate of sequencing error rate, somatic mutation status and genotype probability. The result is that estimate applying Bayesian algorithm even for 50 of small sample size approached real parameter than estimate applying EM algorithm in small sample more accurately.

• ETRI Journal
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• v.28 no.4
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• pp.435-443
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• 2006

This paper presents an efficient carrier recovery algorithm combined with a turbo-coding technique in a mobile communication system. By using a block turbo code made up of independently decodable block codes, we can efficiently recover the fast time-varying carrier phase as well as correct channel errors. Our simulation results reveal that the proposed scheme can accommodate mobiles with high speed, and at the same time can reduce the number of iterations to lock the phase.

• Proceedings of the IEEK Conference
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• 2008.06a
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• pp.283-284
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• 2008

A cross-layer optimization is becoming a popular design methodology for the IP based next generation wireless network. We begin by investigating a cross-layer optimization scheme to enhance the system performance in wireless networks. By applying cross-layer optimization methodology to WiBro distributed network, the WiBro systems are expected to gain significant performance improvement and resource utilization enhanced. For further study we highlight some open challenges and new opportunities for cross-layer design.

• Proceedings of the IEEK Conference
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• 2001.06b
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• pp.349-352
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• 2001

As microprocessor and SOC (System On a Chip) performance moves into the GHz speed, the high-speed asynchronous design is becoming challenge due to the disadvantageous power and speed aspects in synchronous designs. The next generation on-chip systems will consist of multiple independently synchronous modules and asynchronous modules for higher performance, so the interface module for data transfer between multiple clocked IPs is designed with Xilinx FPGA and simulated with RISC microprocessor.