• Corrosion Science and Technology
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• v.15 no.6
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• pp.271-280
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• 2016

An approach to achieving the ambitious goal of cost effectively extending the safe operation life of energy pipeline to 100 years is the application of health monitoring and life prediction tools that are able to provide both long-term remnant pipeline life prediction and in-situ pipeline condition monitoring. A critical step is the enhancement of technological capabilities that are required for understanding and quantifying the effects of key factors influencing buried steel pipeline corrosion and environmentally assisted materials degradation, and the development of condition monitoring technologies that are able to provide in-situ monitoring and site-specific warning of pipeline damage. This paper provides an overview of our current research aimed at developing new sensors and electrochemical cells for monitoring, categorising and quantifying the level and nature of external pipeline and coating damages under the combined effects of various inter-related variables and processes such as localised corrosion, coating cracking and disbondment, cathodic shielding, transit loss of cathodic protection.

• Proceeding of Spring/Autumn Annual Conference of KHA
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• 2005.11a
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• pp.67-72
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• 2005

The purpose of this study was to determine the factors which affect older people's innovativeness toward technologies and factors which affect their demand of home automation system. The study collected data from 289 persons who are 50 years and older with experience living in an apartment currently or past. Innovativeness toward technologies of respondents were low level and the significant factors which affect their innovativeness were age, education, employment, marital status, current housing types, health status of self and spouse, consideration of home automation system for a newly-moved house. Education, employment types, consideration of home automation system for a newly-moved house, and plan for moving were the major factors which affect demand of home automation system. Also, older people's innovativeness toward technologies was the most important factors which affect demand of home automation system. Th results of this study explained that high technologies which are adopted in residential environment should be considered target consumers' abilities and attitudes for acceptance toward new ideas. Especially, for older consumers, various ideas to expand their understanding of new technologies should be developed and the positive effect of technologies to increase the qualify of their later life should be educated.

• Transactions of the Korean hydrogen and new energy society
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• v.27 no.5
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• pp.533-539
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• 2016

This study was performed to evaluate the characteristics of start-up of anaerobic digestion from food waste with different inoculum ratios. The hydrogen yield was similar with different inoculum ratios. The hydrogen production rate increased with increasing inoculum ratio. But the specific hydrogen production rate decreased with increasing inoculum ratio. Total volatile fatty acids composition analysis showed that butyrate and acetate were the prevalent products in all reactors, followed by lactate and propionate. The acetate was most prevalent product in reactors at $X_0/S_0=0.080$ and 0.159. But in reactors at $X_0/S_0=0.239$ and 0.318, butyrate accounted for greater than 50% of the total volatile fatty acids.

• The Journal of the Korean dental association
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• v.52 no.8
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• pp.456-463
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• 2014

Caries Management by Risk Assessment (CAMBRA), published by California Dental Association in 2003, is a customized caries care system that classifies individuals' caries risk into 4 risk groups based on objective evidences and provides chemical treatments targeted for each caries risk level. However, this system was not only developed but also optimized for situation in the United States, resulting into many limitations to be used in Korea, and thus Korean CAMBRA (K-CAMBRA) that considers the clinical situation in Korea needs to be developed. K-CAMBRA includes various techniques that are newly developed in order to overcome the limitations. First, Q-ray, a new optical technology, is utilized in order to avoid the subjectivity of visual inspection during assessment of disease indicators and risk factors. Moreover, Cariview? that reflects the paradigm shift in cariology as a new form of caries assessment kit is used. In addition, considering the situation in Korea, where it is impossible to use high concentration fluoride product, Oral pack with a customized tray is added to increase the contact time of chemical substance. CAMBRA is believed to be the key clinical tool that overcomes the limitations of the paradigm of the conventional restoration-based surgical model of dentistry. Furthermore, it can be expected that Korean dentists can act as oral physicians who are able to control and care individuals' caries risk rather than operative experts who only care about the outcome of caries.

• Journal of The Korea Institute of Healthcare Architecture
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• v.3 no.4
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• pp.35-49
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• 1997

The percentage of postnatal disabled people and elderly population is rapidly increased by the industrialization, and the improvement of medical technology. The disparity between the city and rural area is in the way to disabled people who need rehabilitation. To solve these problems, Community Based Rehabilitation(CBR) is suggested by WHO. In this study, at first, the CBR model considering the specific characteristics of AnSan City are presented. Secondly, the first, the second, and the third rehabilitation facilities in AnSan City are classified by the CBR model. Thirdly, the estimation of optimum space for physical therapy and occupational therapy at rehabilitation center and public health center are sugested, which are the second level rehabilitation facilities. There are some differences in the distribution of population between new and old area in AnSan City. In other words, the subject population of CBR program in old area is relatively higher than that of new area. So, the CBR program for AnSan City must reflect their regional characteristics. In this study, the therapeutic boundaries of second level rehabilitation facilities is decided through the survey of physical therapists and occupational therapists in general hospitals and nursing homes.

• Transactions of the Korean hydrogen and new energy society
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• v.30 no.3
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• pp.269-275
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• 2019

This study was conducted to evaluate the microbial communities in coupled system of a microbial electrolysis cell and an anaerobic digestion. Glucose, butyric acid, propionic acid and acetic acid were used as substrates. The maximum methane production and methane production rate of propionic acid respectively were $327.9{\pm}6.7mL\;CH_4/g\;COD$ and $28.3{\pm}3.1mL\;CH_4/g\;COD{\cdot}d$, which were higher than others. Microbial communities' analyses indicated that acetoclastic methangens were predominant in all systems. But the proportion of hydrogenotrophic methanogens was higher in the system using propionic acid as a substrate when compared to others. In coupled system of a microbial electrolysis cell and anaerobic digestion, the methane production was higher as the distribution of hydrogen, which was generated by substrate degradation, and proportion of hydrogenotrophic methanogens was higher.

• Journal of Microbiology and Biotechnology
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• v.33 no.6
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• pp.797-805
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• 2023

Species belonging to the Vernonia (Asteraceae), the largest genus in the tribe Vernonieae (consisting of about 1,000 species), are widely used in food and medicine. These plants are rich sources of bioactive sesquiterpene lactones and steroid saponins, likely including many as yet undiscovered chemical components. A phytochemical investigation resulted in the separation of three new stigmastane-type steroidal saponins (1 - 3), designated as vernogratiosides A-C, from whole plants of V. gratiosa. Their structures were elucidated based on infrared spectroscopy (IR), one-dimensional (1D) and two-dimensional nuclear magnetic resonance (2D NMR), high-resolution electrospray ionization mass spectrometry (HR-ESI-MS), and electronic circular dichroism analyses (ECD), as well as chemical reactivity. Molecular docking analysis of representative saponins with α-glucosidase inhibitory activity was performed. Additionally, the intended substances were tested for their ability to inhibit α-glucosidase activity in a laboratory setting. The results suggested that stigmastane-type steroidal saponins from V. gratiosa are promising candidate antidiabetic agents.

• Journal of Pharmacopuncture
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• v.19 no.1
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• pp.7-15
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• 2016

Objectives: Malaria has been a major global health problem in recent times with increasing mortality. Current treatment methods include parasiticidal drugs and vaccinations. However, resistance among malarial parasites to the existing drugs has emerged as a significant area of concern in anti-malarial drug design. Researchers are now desperately looking for new targets to develop anti-malarials drug which is more target specific. Malarial parasites harbor a plastid-like organelle known as the 'apicoplast', which is thought to provide an exciting new outlook for the development of drugs to be used against the parasite. This review elaborates on the current state of development of novel compounds targeted againstemerging malaria parasites. Methods: The apicoplast, originates by an endosymbiotic process, contains a range of metabolic pathways and housekeeping processes that differ from the host body and thereby presents ideal strategies for anti-malarial drug therapy. Drugs are designed by targeting the unique mechanism of the apicoplasts genetic machinery. Several anabolic and catabolic processes, like fatty acid, isopenetyl diphosphate and heme synthess in this organelle, have also been targeted by drugs. Results: Apicoplasts offer exciting opportunities for the development of malarial treatment specific drugs have been found to act by disrupting this organelle's function, which wouldimpede the survival of the parasite. Conclusion: Recent advanced drugs, their modes of action, and their advantages in the treatment of malaria by using apicoplasts as a target are discussed in this review which thought to be very useful in desigining anti-malarial drugs. Targetting the genetic machinery of apicoplast shows a great advantange regarding anti-malarial drug design. Critical knowledge of these new drugs would give a healthier understanding for deciphering the mechanism of action of anti-malarial drugs when targeting apicoplasts to overcome drug resistance.

• Journal of Soil and Groundwater Environment
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• v.27 no.4
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• pp.1-9
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• 2022

This study was conducted to supplement new-normal strategies on management plans of rural groundwater resources in the era of Post COVID-19. Global outbreak of COVID-19 has damaged across all areas including public policy, economics, industrial services, and others without exception, which has resulted in establishing new-normal strategies in order to restore balance and functions as for these areas. The new-normal ones were represented as enhancing preventative management on infectious diseases, expanding non face-to-face services, enhancing protective trades and food securities, and preparing growth policies on public services using the 4^th industrial revolution techniques. In this study, G-WASH_AD (Groundwater supply, sanitation, and hygiene with attraction and digitization) was suggested to be new-normal strategies on rural groundwater resources. The G-WASH_AD was consisted of three detailed action plans: a preventative plan on waterborne-diseases of groundwater (PP), a groundwater-tourism plan with rural heritage (GP), and an application plan of the 4^th industrial revolution techniques to groundwater facilities and its data (P4). The PP can contribute to protect human health from waterborne-diseases and minimize hazardous effects on crop cultivation. The GP accompanied with high-quality groundwater resources is able to strengthen rural tourism, to promote marketing activities on local agricultural products, and to increase household incomes of rural communities. The P4 can reinforce fast, comfortable, and scientific management on groundwater facilities and its data, creating a virtuous cycle between innovative management on groundwater and growth of technology related to it. Results of the G-WASH_AD strategies can encourage a green growth engine in field of rural groundwater management keeping up with Post COVID-19.

• Journal of Dairy Science and Biotechnology
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• v.32 no.1
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• pp.55-62
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• 2014

This study aims to suggest a management system consisting of functional ingredients by establishing guidelines for the analysis of functional animal products in Korea. Further, the guidelines can be used for validity tests of functional animal products. In addition, we can standardize the management system for details, and frame new laws for functional animal products. We researched the current studies on the analysis and assessment of functional foods, and established standard methods of analysis. We devised new analysis and assessment techniques to determine the efficacy and safety of functional ingredients for the legislation and management of functional animal products. This study may contribute to not only the safety and quality of functional animal products but also to enhancing the nation's health and the national image as being health-oriented, through improvements in the productivity and quality of functional animal products.