• 한국방사성폐기물학회:학술대회논문집
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• 한국방사성폐기물학회 2019년도 춘계학술논문요약집
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• pp.145-146
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• 2019

• 한국지역지리학회지
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• 제8권2호
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• pp.150-160
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• 2002

본 연구는 1980년대 이후 주로 영어권 국가들에서 논의되고 있는 지역지리 연구의 새로운 논의들을 개략적으로 정리하여 그 윤곽을 소개하려는 것이다. 새로운 지역지리 논의는 지리학자들과 사회이론가들과의 활발한 지적 교류가 중요한 계기가 되었다. 신지역지리학을 주창하는 사람들은 공간이 수행하는 역할에 대하여 보다 적극적인 의미를 부여한다. 공간은 그 속에 온갖 사상(事象)(things)을 담고 있는 용기(容器)(containers)가 아니다. 그것은 한낱 어떤 존재의 외부환경에 불과한 것이 아니라, 존재를 존재이게 하는 본질적 차원이다. 신지역지리학은 크게 네 갈래로 논의가 전개되고 있다. 구조화 이론에서 출발하여 시간지리학으로 연결되는 연구 흐름, 공간적 분업론을 기반으로 지역문제에 포괄적으로 접근하고 있는 연구들, 그리고 세계체계론을 공간적 관점에서 재해석하려는 연구들, 마지막으로 탈-후기구조주의 시대에 인간주체를 강조하려는 연구가 그것이다. 그러나 신지역지리 연구는 이론적 논의에 비해 아직 경험적 연구가 많이 축적되지 못한 편이다. 그 이유는 신지역지리 연구이념을 구체적인 경험적 연구로 이어주는 중범위 수준의 개념들이 아직 충분히 개발되지 못하고 있기 때문이다.

• Journal of Biosystems Engineering
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• 제37권4호
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• pp.258-264
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• 2012

Purpose: This review aims at introducing 3 modeling approaches classified into 3 categories based on the purpose (estimation or prediction), structure (linear or non-linear) and phase (steady-state or dynamic-state); 1) statistical approaches, 2) kinetic modeling and 3) mechanistic modeling. We hope that this review can be a useful guide in the model-based approach of calcium metabolism as well as illustrates an application of engineering tools in studying biosystems. Background: The meaning of biosystems has been expanded, including agricultural/food system as well as biological systems like genes, cells and metabolisms. This expansion has required a useful tool for assessing the biosystems and modeling has arisen as a method that satisfies the current inquiry. To suit for the flow of the era, examining the system which is a little bit far from the traditional biosystems may be interesting issue, which can enlarge our insights and provide new ideas for prospective biosystem-researches. Herein, calcium metabolic models reviewed as an example of application of modeling approaches into the biosystems. Review: Calcium is an essential nutrient widely involved in animal and human metabolism including bone mineralization and signaling pathways. For this reason, the calcium metabolic system has been studied in various research fields of academia and industries. To study calcium metabolism, model-based system analyses have been utilized according to the purpose, subject characteristics, metabolic sites of interest, and experimental design. Either individual metabolic pathways or a whole homeostasis has been modeled in a number of studies.

• 대한예방한의학회지
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• 제20권1호
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• pp.99-110
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• 2016

In Korea and China, traditional medicine's holistic approaches, based on the views of whole-body and whole-person, have been applied to make the solution of health problem. However, these holistic approaches of traditional korea or chinese medicine have been limited in interpreting their theories in a view of modern scientific aspects of medicine. This limitation seems to be mainly due to the reductionism approaches of modern scientific medicine. Traditionally, science has taken a reductionism approach; dissecting biological systems into their constituent parts and studying them in isolation. However, systems biology based on omics technologies is providing a new thought and method for traditional medicine's research and interpretation. Systems biology uses integrity study as the characteristic and bioinformatic technology as the key method for connecting reductionism and holism. Therefore, it has much in common with the theory of traditional medicine. It was reviewed that how systems biology is applied to traditional medicine in Korea and China. Also it was suggested that more future researches on interpretation between traditional medicine and systems biology must be focused on personalized medicine since systems biology will have a major impact on future personalized therapeutic approaches.

• Structural Engineering and Mechanics
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• 제73권6호
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• pp.699-714
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• 2020

Force based design (FBD) approach is prevalent in most of the national seismic design codes world over. Direct displacement based design (DDBD) and energy based design (EBD) approaches are relatively new methods of seismic design which claims to be more rational and predictive than the FBD. These three design approaches are conceptually distinct and imparts different strength, stiffness and ductility property to structural members for same plan configuration. In present study behavioural assessment of frame of six storey RC building designed using FBD, DDBD and EBD approaches has been performed. Lateral storey forces distribution, reinforcement design and results of nonlinear performance using static and dynamic methods have been compared. For the three approaches, considerable difference in lateral storey forces distribution and reinforcement design has been observed. Nonlinear pushover analysis and time history analysis results show that in FBD frame plastic deformation is concentrated in the lower storey, in EBD frame large plastic deformation is concentrated in the middle storeys though the inelastic hinges are well distributed over the height and, in DDBD frame plastic deformation is approximately uniform over the height. Overall the six storey frame designed using DDBD approach seems to be more rational than the other two methods.

• Journal of Computing Science and Engineering
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• 제2권2호
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• pp.109-136
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• 2008

In this survey paper, we discuss biomedical ontologies and major text mining techniques applied to biomedicine and healthcare. Biomedical ontologies such as UMLS are currently being adopted in text mining approaches because they provide domain knowledge for text mining approaches. In addition, biomedical ontologies enable us to resolve many linguistic problems when text mining approaches handle biomedical literature. As the first example of text mining, document clustering is surveyed. Because a document set is normally multiple topic, text mining approaches use document clustering as a preprocessing step to group similar documents. Additionally, document clustering is able to inform the biomedical literature searches required for the practice of evidence-based medicine. We introduce Swanson's UnDiscovered Public Knowledge (UDPK) model to generate biomedical hypotheses from biomedical literature such as MEDLINE by discovering novel connections among logically-related biomedical concepts. Another important area of text mining is document classification. Document classification is a valuable tool for biomedical tasks that involve large amounts of text. We survey well-known classification techniques in biomedicine. As the last example of text mining in biomedicine and healthcare, we survey information extraction. Information extraction is the process of scanning text for information relevant to some interest, including extracting entities, relations, and events. We also address techniques and issues of evaluating text mining applications in biomedicine and healthcare.

• 대한수학회보
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• 제48권4호
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• pp.791-812
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• 2011

This is a survey on American options. An American option allows its owner the privilege of early exercise, whereas a European option can be exercised only at expiration. Because of this early exercise privilege American option pricing involves an optimal stopping problem; the price of an American option is given as a free boundary value problem associated with a Black-Scholes type partial differential equation. Up until now there is no simple closed-form solution to the problem, but there have been a variety of approaches which contribute to the understanding of the properties of the price and the early exercise boundary. These approaches typically provide numerical or approximate analytic methods to find the price and the boundary. Topics included in this survey are early approaches(trees, finite difference schemes, and quasi-analytic methods), an analytic method of lines and randomization, a homotopy method, analytic approximation of early exercise boundaries, Monte Carlo methods, and relatively recent topics such as model uncertainty, backward stochastic differential equations, and real options. We also provide open problems whose answers are expected to contribute to American option pricing.

• Journal of Plant Biotechnology
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• 제7권1호
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• pp.1-15
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• 2005

Salinity is one of the major limiting factors for agricultural productivity. In plants, accumulation of osmolytes plays a pivotal role in abiotic stress tolerance. Likewise, exclusion or compartmentation of $Na^+$ ions into vacuoles provides an efficient mechanism to avert deleterious effects of $Na^+$ in the cytosol. Both vacuolar and plasma membrane sodium transporters and $H^+-ATPases$ can provide the necessary ion homeostasis. A variety of crop plants were engineered with respect to the synthesis of osmoprotectants and ion-compartmentation, but there are other cellular pathways involved in the salinity responses that are still not completely explored. Genomics approaches are increasingly used to identify genes and pathway changes involved in salt-tolerance. The new knowledge may be used via guided genetic engineering of multiple genes to create crop plants with significantly increased productivity in saline soils. This review surveys how plants deal with high salt conditions and how salt tolerance can be improved by transgenic approaches.

• 농촌지도와개발
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• 제7권2호
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• pp.359-376
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• 2000

The purposes of this exploratory study were to interrelate the scholastic discipline of the ‘development communication’ into ‘community development’ and ‘adult education’ in terms of interests, views and theoretical backgrounds of these fields of social sciences; and to draw some implications for developing scholastic interactions among these fields to pursue common social changes of human society. Development communications provide opportunities to set goals, to decide contents, and to utilize communication media in developmental efforts. Contemporary trends of development communication, community development and adult education are concerned with indigenous, two-way, bottom-up and people-centered communication from exogenous, one-way, top-down and institution-centered communication of the past. Multidisciplinary approaches to communication concepts and methodology may increase the potentials of community development and adult education in terms of efficiency and effectiveness. Some of the development communication approaches such as traditional and folk media approach. new media or ICT(information & communication technology) approach, participatory communication for development approach, communication support development approach and mass media approach may be applicable for community development and adult education. Better understanding on development communication approaches will be needed for the adult educators as well as community development practitioners.

• 대한수학교육학회지:학교수학
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• 제5권3호
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• pp.343-360
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• 2003

초등수학에서 중등수학으로의 이행에서 대수는 중요한 역할을 한다. 그리고 학교수학에서 어떻게 대수를 도입하는가 하는 문제는 중등수학 전반에서 그 성공여부를 결정짓는 중요한 요소가 된다. 일반적으로 학교대수는 대수 기호를 형식적으로 도입하는 전통적인 접근법을 따르고 있다. 이것은 대수를 일반화된 산술이라는 관점에서 보는 것으로, 여기서 문제는 이러한 접근법에서 학생들이 많은 어려움을 경험한다는데 있다. 따라서 이 글은 이러한 어려움을 해결하기 위한 하나의 대안으로 형식적인 대수 지도 방법을 대신하여 패턴과 일반화 측면을 강조하여 대수를 지도하는 방법에 대해 살펴보고자 한다. 이것은 대수를 도입하는 다양한 관점 곧, 문제해결과 모델링, 일반화된 산술을 비롯하여 함수를 포함하며, 동시에 대수에 내재된 패턴을 통해 대수학습에서 핵심으로 다루어지는 일반화라는 사고 양식을 이끌어내기 위한 것이다. 이를 위해 이 글은 먼저 대수와 패턴, 일반화 사이의 관계를 살펴보고, 그리고 패턴과 일반화를 강조한 대수 접근법이 대수 수업의 실제에서 어떻게 제시될 수 있는가에 대해 살펴볼 것이다.