• Macromolecular Research
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• v.16 no.6
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• pp.561-566
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• 2008

NR composites with different curing systems were aged thermally at 60, 70, 80, and $90^{\circ}C$ for 2-185 days in a convection oven, and the changes in the crosslink density were investigated as a function of the accelerated thermal aging. The overall crosslink densities increased with increasing aging time irrespective of the aging temperatures and curing systems. The changes in crosslink density were enhanced by increasing the aging temperature. The degree of the increased crosslink density was in the following order: "the conventional cure system > the semi-EV system > the EV system". For short term thermal aging, the change in crosslink density with the aging time was complicated, particularly for low temperature aging. The activation energies of the change in crosslink density with thermal aging using the conventional and semi-EV cure systems increased and then remained relatively constant with increasing aging time, whereas that of the specimen with an EV cure system tended to increase linearly. The experimental results were explained by the dissociation of the existing polysulfidic linkages and the formation of new cross links through the crosslinking-related chemicals remaining in the sample.

• Korean Journal of Plant Resources
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• v.35 no.3
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• pp.391-398
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• 2022

Ulcerative colitis (UC) is a typical inflammatory colon disorder. Platycodon grandiflorum (PG) is known to exert various beneficial effects including anti-oxidative and anti-bacterial properties and improvements in liver function. However, the improving effect and mechanism of PG on intestinal inflammation are not fully understood. The present research was designed to investigate the effect of PG on the clinical signs of DSS-induced colitis in mice. The ameliorative effects of PG on inflammatory cytokine expression and the activation of hypoxia-inducible-factor (HIF)-1α in DSS-treated colon tissue were also determined. Our results showed that mice treated with DSS displayed the main clinical symptoms of colitis, including weight loss, bloody stools, decrease in colon length and diarrhea and PG treatment significantly improved the clinical features induced by DSS in mice. PG inhibited the increase in the levels of inflammatory cytokines caused by DSS in colon tissues. We also showed that the anti-inflammatory mechanism of PG involved suppressing the activation of HIF-1α in DSS-treated colon tissues. Collectively, the findings of this study indicate the prospect of developing new drugs from PG for UC treatment.

• Journal of the Korean Institute of Rural Architecture
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• v.14 no.4
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• pp.1-9
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• 2012

Recently, the central and local government support various improvement projects on existing public buildings and areas. Improving public use and environment of these areas is adequate because financial condition of local city is not enough to build new infrastructures. As one of the projects, Geochang-Eup(Geochang-Gun, Gyeongnam Province) is selected as the project site since most of the public buildings and areas of the city are located close each other in downtown but not streamlined in function and use nor easily accessible. The purpose of this study is to analyze the causes of decline in local city and to present strategies to vitalize the city through improving environment of public areas. And we analyzed the problems by discussion with local officer, field investigation on the site and paper survey. The analysis shows that public infrastructures are grouped by function: administration, education, life support, culture, health, etc, but not well-connected, easily accessible, adequately located, various in use nor enough in quantity. This study summarized the problems into five categories: Access&Linkage, Safe&Comfort, Identity&Image, Usage&Activity and Ownership&Management and proposes strategy in three phases. The first phase is to improve functions and design of public places per each area: more consistent design on public buildings, better civil facilities and better accessibility to public areas. The second is to vitalize of the areas and to improve efficiency in use through linking each other physically and sharing uses. The third is to encourage citizen's participation and by developing civil programs to streamline public areas each other.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.21 no.7
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• pp.103-108
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• 2007

Neural network is used in many fields of control systems currently. However, It is not easy to obtain input-output pattern when neural network is used for the system of a single feedback controller and it is difficult to get satisfied performance with neural network when load changes rapidly or disturbance is applied. To resolve these problems, this paper proposes a new mode to implement a neural network controller by installing a real object in place of activation function of Neural Network output node. As the Neural Network self adaptive control system is designed in simple structure neural network input-output pattern problem is solved naturally and real tin Loaming becomes possible through general back propagation algorithm. The effect of the proposed Neural Network self adaptive control algorithm was verified in a test of controlling the speed of a A.C. servo motor equipped with a high speed computing capable DSP (TMS320C32) on which the proposed algorithm was loaded.

• Proceedings of the Korean Vacuum Society Conference
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• 2014.02a
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• pp.128.2-128.2
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• 2014

Long-wave infrared detectors using the type-II InAs/GaSb strained superlattice (T2SL) material system with the nBn structure were designed and fabricated. The band gap energy of the T2SL material was calculated as a function of the thickness of the InAs and GaSb layers by the Kronig-Penney model. Growth of the barrier material (Al0.2Ga0.8Sb) incorporated Te doping to reduce the dark current. The full width at half maximum (FWHM) of the 1st satellite superlattice peak from the X-ray diffraction was around 45 arc sec. The cutoff wavelength of the fabricated device was ${\sim}10.2{\mu}m$ (0.12eV) at 80 K while under an applied bias of -1.4V. The measured activation energy of the device was ~0.128 eV. The dark current density was shown to be $1.2{\times}10^{-5}A/cm^2$ at 80 K and with a bias -1.4 V. The responsivity was 1.9 A/W at $7.5{\mu}m$ at 80K and with a bias of -1.9V.

• 제어로봇시스템학회:학술대회논문집
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• 2000.10a
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• pp.494-494
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• 2000

This paper demonstrates that the largest Lyapunov exponent $\lambda$ of recurrent neural networks can be controlled by a gradient method. The method minimizes a square error $e_{\lambda}=(\lambda-\lambda^{obj})^2$ where $\lambda^{obj}$ is desired exponent. The $\lambda$ can be given as a function of the network parameters P such as connection weights and thresholds of neurons' activation. Then changes of parameters to minimize the error are given by calculating their gradients $\partial\lambda/\partialP$. In a previous paper, we derived a control method of $\lambda$via a direct calculation of $\partial\lambda/\partialP$ with a gradient collection through time. This method however is computationally expensive for large-scale recurrent networks and the control is unstable for recurrent networks with chaotic dynamics. Our new method proposed in this paper is based on a stochastic relation between the complexity $\lambda$ and parameters P of the networks configuration under a restriction. Then the new method allows us to approximate the gradient collection in a fashion without time evolution. This approximation requires only $O(N^2)$ run time while our previous method needs $O(N^{5}T)$ run time for networks with N neurons and T evolution. Simulation results show that the new method can realize a "stable" control for larege-scale networks with chaotic dynamics.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2006.11a
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• pp.133-137
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• 2006

Can examine cause that the construction industry is faced in crisis of skill exhaustion in two sides. One is the tribe of actuality production manpower by entry evasion and graying of young man class specially new manpower to the tribe of skill manpower. Another is qualitative decline of skill manpower. Generally, problem of the systematic knowledge tribe and the picking up tribe about new technology etc, exists because learn skill for shoulder beyond in spot. In cutting phenomenon of skill that is depended on personal relationships availability with skilled worker in hereafter, problem that worker who is old or enter through rain skilled worker does not learn all life skill is detected. These problems institute entry of young man class and necessity of systematic vocational education training specially new human strength strongly. This study does presentation of way to promote construction industry entry of young man class and improvement way of vocational education training system that can do to train these by function manpower by purpose.

• The Korean Journal of Physiology and Pharmacology
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• v.17 no.1
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• pp.37-42
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• 2013

Taxifolin glycoside is a new drug candidate for the treatment of atopic dermatitis (AD). Many drugs cause side effects such as long QT syndrome by blocking the human ether-a-go-go related gene (hERG) $K^+$ channels. To determine whether taxifolin glycoside would block hERG $K^+$ channels, we recorded hERG $K^+$ currents using a whole-cell patch clamp technique. We found that taxifolin glycoside directly blocked hERG $K^+$ current in a concentration-dependent manner ($EC_{50}=9.6{\pm}0.7{\mu}M$). The activation curve of hERG $K^+$ channels was negatively shifted by taxifolin glycoside. In addition, taxifolin glycoside accelerated the activation time constant and reduced the onset of the inactivation time constant. These results suggest that taxifolin glycoside blocks hERG $K^+$ channels that function by facilitating activation and inactivation process.

• Journal of Radiation Protection and Research
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• v.29 no.1
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• pp.17-23
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• 2004

In order to save time and money needed in the purchase commonly used gamma-ray standard sources, a new radioactive standard source was manufactured by the neutron activation of some regent in the research reactor HANARO. The source was manufactured with an aqueous solution by mixing and dissolving the irradiated reagents. The manufactured source was compared with a commercial standard source. It was confirmed that it could be used as an efficiency calibration source. Also, in order to compare the variation of efficiency due to the volume difference for various containers used in radioactivity assay, the efficiency variation as a function of sample volume was investigated.

• Journal of Ginseng Research
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• v.36 no.4
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• pp.375-382
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• 2012

Ginsenoside Rp1 (G-Rp1) is a saponin derivate that provides anti-metastatic activities through inhibition of the NF-${\kappa}B$ pathway. In this study, we examined the effects of G-Rp1 on regulatory T cell (Treg) activation. After treatment of splenocytes with G-Rp1, Tregs exhibited upregulation of IL-10 expression, and along with dendritic cells (DCs), these Tregs showed increased cell number compared to other cell populations. The effect of G-Rp1 on Treg number was augmented in the presence of lipopolysaccharide (LPS), which mimics pathological changes that occur during inflammation. However, depletion of DCs prevented the increase in Treg number in the presence of G-Rp1 and/or LPS. In addition, G-Rp1 promoted the differentiation of the memory types of $CD4^+Foxp3^+CD62L^{low}$ Tregs rather than the generation of new Tregs. In vivo experiments also demonstrated that Tregs and DCs from mice that were fed G-Rp1 for 7 d and then injected with LPS exhibited increased activation compared with those from mice that were injected with LPS alone. Expression of TGF-${\beta}$ and CTLA4 in Tregs was increased, and upregulation of IL-2 and CD80/CD86 expression by DCs affected the suppressive function of Tregs through IL-2 receptors and CTLA4. These data demonstrate that G-Rp1 exerts anti-inflammatory effects by activating Tregs in vitro and in vivo.