Background: The DR-$70^{TM}$ immunoassay is a newly developed cancer diagnostic test which quantifies the serum fibrin degradation products (FDP), produced during fibrinolysis, by antibody reaction. The purpose of this study was to evaluate the potential of DR-$70^{TM}$ Immunoassay in screening malignant tumor. Methods: Sample subjects were 4,169 adults, both male and female, who visited the health promotion center of a general hospital from March 2004 to April 2005 and underwent the DR-$70^{TM}$ immunoassay test and other tests for cancer diagnosis. The patient group was defined as 42 adults out of the sample subjects who were newly diagnosed with cancer during the same time period when the DR-$70^{TM}$ immunoassay test was performed. Final confirmation of a malignant tumor was made by pathological analysis. Results: The mean DR-$70^{TM}$ level was $0.83{\pm}0.65{\mu}g/ml$ (range: 0.00 (0.0001)${\sim}7.42{\mu}g/ml)$ in the control group (n=4,127) as opposed to $2.70{\pm}2.33{\mu}g/ml$ (range: $0.12{\sim}9.30{\mu}g/ml)$ in the cancer group (n=42), and statistical significance was established (p<0.0001, Student t-test). When categorized by the type of malignant tumor, all cancer patients with the exception of the subgroups of colon and rectal cancer showed significantly higher mean DR-$70^{TM}$ levels compared with the control group (p<0.0001, Kruscal-Wallis test). The receiver operating characteristic (ROC) curve analysis revealed ${\geq}1.091{\mu}g/ml$ as the best cut-off value. Using this cut-off value, the DR-$70^{TM}$ immunoassay produced a sensitivity of 71.4%, a specificity of 70.1%, a positive predictability of 69.4%, and a negative predictability of 69.2% (1). Conclusion: A significant increase in the mean DR-$70^{TM}$ value was observed in the cancer group (thyroidal, gastric, breast, hepatic and ovarian) com pared with the control group. In particular, the specificity and sensitivity of the DR-$70^{TM}$ immunoassay was relatively high in the subgroups of breast, gastric, and thyroidal cancer patients. There is need for further studies on a large number of malignant tumor patients to see how the DR-$70^{TM}$ level might be changed according to the differentiation grade and postoperative prognosis of the malignant tumor.
This study is a methodological research study to develop an instrument to measure in patients with cancer and to test the validity and reliability of the instrument. The research procedure was as follows : 1) The first step was to develop conceptual framework based on a comprehensive review of the literature and in-depth interviews with patients with cancer. This conceptual framework was organized in to three dimensions (the intrapersonal dimension, the significant-other and context related dimension, the transcendental dimension). Initially 59 items were adopted. 2) These items were analyzed through the index of content validity(CVI) and 53 items were selected which met more than 80% on the CVI. 3) The pretest was carried out with 87 patients with cancer. After the pretest results were analyzed by item analysis, 44 items were selected. A second test of content validity was conducted and 6 items were eliminated considering the 80% CVI. 4) To test for reliability and validity, data collection was done during the period from January 25, 1999, to February 26, 1999. The subjects for the test were 160 patients with cancer and 185 healthy persons. analysis, item analysis and multitrait-multimethod method to analyze validity. The findings are as follows : 1) The Cronbach's alpha coefficient for internal consistency was .92 for the total 38 items and .79, .82, .85, for the three dimensions in that order. 2) The item analysis was based on the corrected item to total correlation coefficient( .30 or more) and information about the alpha estimate if this item was dropped from the scale. 3) As a result of the initial factor analysis using principal component analysis and varimax rotation, one item was deleted because of factor complexity (indiscriminate factor loadings). In the secondary factor analysis, 7 factors with eigenvalue of more than 1.0 were extracted and these factors explained 56 percents of the total variance. The seven factors were labeled as 'family relationship', 'emotional condition', 'physical discomfort', 'meaning and goal of life', 'contextual stimuli', 'change of body image', 'guilt feelings'. 4) The convergence effect between this instrument and the life satisfaction scale was identified and there was significant positive correlation(r= .52, p= .00). The discriminant validity between this instrument and the depression scale(CES-D) was tested and there was significant negative correlation(r= -.50, p= .00). The instrument for accessing the suffering of patients with cancer developed in this study was identified as a tool with a high degree of reliability and validity. In this sense, this tool can be effectively utilized for assessment in caring for patients with cancer.
Kim, Ji-Kwang;Gu, Hong;An, Jin-Suk;Kook, Min-Suk;Park, Hong-Ju;Oh, Hee-Kyun;Cho, Jin-Hyoung
Journal of the Korean Association of Oral and Maxillofacial Surgeons
/
v.32
no.6
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pp.566-574
/
2006
Purpose : This study was performed to provide an anatomical information of the mandibular ramus for the successful inferior alveolar nerve block. Three dimensional images were reconstructed from the computerized tomography (CT) and the anatomical evaluation of the mandibular ramus was done. Materials and methods : Sixty-four patients who had been taken the facial CT scans from 2000, Jan to 2003, June was selected. The patients who had the anterior or posterior teeth misssing, edentulous ridge, and jaw fracture were excepted. In the occulusal plane, the lingual surface angle (LSA) between the mid-sagittal plane and the mandibular molar lingual surface from the 2nd premolar to the 2nd molar, the inner ramal surface angle (IRSA), the maximum inner ramal surface angle (MxIRSA), and the outer ramal surface angle (ORSA) to the-mid sagittal plane were measured. The inner ramal surface angle in the ligular tip level (IRSA-L) and the outer ramal surface angle in the ligular tip level (ORSA-L), the ramal length (RL), and the anterior ramal length (ARL) were also measured in the lingular tip level. Results : In the lingular tip level, the mean IRSA-L and ORSA-L were $28.6{\pm}6.3^{\circ}$ and $17.9{\pm}4.9^{\circ}$ respectively. The larger was the IRSA, the larger was the ORSA. In the lingular tip level, the mean ramal length was 35.8${\pm}$3.4 mm. The larger was the IRSA-L, the shorter was the ramal length. On the lingular tip level, the mean anterior ramal length from anterior ramus to lingular tip was 19.6${\pm}$3.3 mm. when the ramal length was longer, the anterior ramal length was also longer. On the lingular tip level, there was positive correlation vetween the IRSA and the ORSA, negative correlation between the IRSA and the ramal length, and positive correlation between the ramal length and the lingular tip level to the anterior ramus. There was no statistical meaning of data between sex and age. Conclusion : In the clinical view of the results so far achieved, if the direction of needle is closer to posterior it is able to contact bone on lingular tip when the internal surface of ramus is wided outer.
Journal of the Korean Institute of Landscape Architecture
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v.44
no.5
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pp.92-102
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2016
While there have many completions of large parks recently under development, there has been a dearth of quality assessments. Studies focused on post-evaluation have been made to resolve this, but most of these are biased toward user satisfaction after completion and therefore behaviour analysis has limitations on solving problemsduring the actual design implementation processes. Therefore, this study examined the internal phenomenon and structure of the implementation process of design competition through the ground theory and microscopic independent perspective. As a result, maintaining the identity and differentiation of parks derived from the preserved design competition scheme contributed greatly to completeness and satisfaction. Outcomes were mainly caused by the trust of public officials as the ordering organization, the will of policy decision-makers, and the competence of operational enterprises, etc. Negative factors such as undermining the whole concept of the park and landscape occurred as external pressure and related subjects intruded on change design factors due to variations in social conditions. Additionally, illogical construction processes occurred, such as a reinvestigation of the budget for restoration after damaging on original landscape. There have been needs for the improvement of the work processing system. On balance, an interventional role is very important in the park construction process, especially the PA and operation committee in terms of maintaining the basic direction, landscape design supervision for detailed designs, and expert construction management on LA in terms of rational work management in the field. The study, using the microscopic perspective of the designer and ground theory, deliver significant meaning as an early study by suggesting alternative methods for the after-evaluation of large parks and structurally looking into main influence factors driven during the construction process.
Kim, Jeong In;Park, Sang Jin;Kim, Hyoung Ju;Choi, Jun Ho;Kim, Han Il;Kim, Pan Koo
Smart Media Journal
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v.9
no.1
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pp.51-59
/
2020
From PC communication to the development of the internet, a new term has been coined on the social media, and the social media culture has been formed due to the spread of smart phones, and the newly coined word is becoming a culture. With the advent of social networking sites and smart phones serving as a bridge, the number of data has increased in real time. The use of new words can have many advantages, including the use of short sentences to solve the problems of various letter-limited messengers and reduce data. However, new words do not have a dictionary meaning and there are limitations and degradation of algorithms such as data mining. Therefore, in this paper, the opinion of the document is confirmed by collecting data through web crawling and extracting new words contained within the text data and establishing an emotional classification. The progress of the experiment is divided into three categories. First, a word collected by collecting a new word on the social media is subjected to learned of affirmative and negative. Next, to derive and verify emotional values using standard documents, TF-IDF is used to score noun sensibilities to enter the emotional values of the data. As with the new words, the classified emotional values are applied to verify that the emotions are classified in standard language documents. Finally, a combination of the newly coined words and standard emotional values is used to perform a comparative analysis of the technology of the instrument.
The tennis was one of the most popular sport in the general physical education lesson. However there are many problems such as difficult of improvement tennis skill, lack of class days and so many students in a class. These reasons could ultimately damage the overall quality of class. The purpose of this research was to beginner students was fun and easy to learn. The tennis lesson using tools were 1.selective hitting ball, 2. high net hitting ball, 3. hitting orange ball. Scores of the experimental group(n=23) and the control group(n=21) were compared. In order to verify course content was the same 15 weeks, conducted a tennis teaching methods to take advantage of the tools. And tools to take advantage of the students who participated in a class analysis of the qualitative data (interviews, documents, questionnaires, observations, journals). As a result, the satisfaction scores of the experimental group were higher than those of the control group. The tennis lesson using tools to take positive effect(meaning, improved skill, easy, fun/curious/confident) and negative effect(difficulties of adaptation, a high challenge level) was induced. In summary of the quantitative/qualitative data 'Orange Ball' has a positive impact on the girls than boys and teaching methods using tools gave generally positive influence to students.
The purpose of this study is to analyze high school students' understanding levels about earth science terms written in Chinese characters according to learners' characteristics. In order to investigate how the responses vary according to their characteristics, first of all, proper scientific terms are selected, and then corre sponding questions about them are offered as subjects, which consists of a Korean characters type, a picture type, and a Korean and Chinese characters type. During paper test and interview, the questions are given to fifteen students from general high schools in Jecheon, Chungbuk Province. The results of the study are as follows; Students in formal operation level and field-independency answered very well and also the terms of Chinese characters type and picture type improve the students' understanding and memorization. Generally, Chinese characters have more positive influence on their learning than the negative. Therefore, in general, it seems that it's more effective to explain the sound and meaning of terms in detail and to give learners enough time to draw a picture about each term by themselves when scientific terms are delivered to students in Chinese characters in class.
We created species richness maps of mammals, birds and plants using "Nnational Ecosystem Survey" data and identified correlations between species richness maps of each taxa. We examine the distribution of species richness of each taxa and calculated conservation priority rank through plotting species-area curves using an additive benefit function in Zonation. The conclusions of this study are as follows. First, plant showed high species richness in Gangwon province and Baekdudaegan, and mammals showed high species richness at eastern slope of Baekdudaegan in Gangwon province unusually and the species richness of mammals distributed equally except Gyeonggi and Chungnam province. However, birds showed high species richness in the west costal because the area is the major route of winter migratory birds. Second, correlation of each taxa's distribution is not significant. Correlation between mammals and birds is positive but correlations between birds and others are negative. Because mammals inhabit in forest but birds mostly live in coastal wetlands and rivers. Therefore, bird's habitats are not shared with other habitats. Third, the probability of mammals occurrence is very low under 25% in species-area curve, others increase proportionally to area. Birds increase dramatically richness at 10% because bird's habitat is concentrated in coastal wetlands and rivers. Plants increased gently species richness due to large forest in Gangwon province. We can calculate the predicted number of species in curves and plan various conservation strategies using the marginal number of species. Finally, high priority ranks for conservation distributed mainly in Gangwon province and Baekdudaegan. When we compared with priority map and terrestrial national parks, the parks were evaluated as high priority ranks. However, the rank of parks away from Baekdudaegan was low. This study has the meaning of selecting conservation priority area using National Ecosystem Survey. In spite of the omission of survey data in national parks and Baekdudaegan, the results were good. Therefore, the priority rank method using species distribution models is useful to selecting protected areas and improving conservation plans. However, it is needed to select protected areas considering various evaluation factors, such as rarity, connectivity, representativeness, focal species and so on because there is a limit to select protected area only using species richness.
Journal of Korean Academy of Nursing Administration
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v.8
no.3
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pp.431-439
/
2002
Purpose : Nursing profession has been rapidly changed due to the development of bioscience and the change of medical service environment. Nursing profession that has been focused on only care giver's role like mother's in tradition, is required careful reflection new nursing role to cope properly to the change of medical service environment. In nursing profession, the concept of the role was used without an accurate definition, as a results, the concept of the role was mixed with the concept of the "activity", "job" and "function". Therefore, concept analysis of the role in nursing profession is needed to remove conceptual ambiguous and make confirm the true meaning of the role. Concept analysis is a strategy that examine the characteristics of a concept. It is a formal linguistic exercise to determine those defining attributes. The basic purpose of concept analysis is to clarify ambiguous concept in theory, and propose operational definition which reflects the theoretical base of the concept. Method : In this study, the concept of the role in nursing profession which was analyzed based on the steps of concept analysis by Walker & Avant(1988). Results : The attributes of the concept of the role in nursing profession are : 1. Basic factors to construct social structure. 2. Expected attitudes, values, behavior patterns according to the social status and position in social structure. 3. Perceptive attitudes, values, behavior patterns in order to social interaction. 4. Acquiring through continuous communication and learning. 5. Not fixative but changeable. The antecedents of the role in nursing profession are : 1. The social status and position which is possessed by a person. 2. Expected attitudes, values, behavior patterns according to the social status and position in social structure. 3. Acquiring through continuous interaction, communication, and learning process. And the consequences of the role in nursing profession are : 1. The role maintenance and the role expansion as a positive consequences. 2. The role conflict and the role loss as a negative consequences. Conclusion : Through this concept analysis, the concept of the role in nursing profession is defined as As basic factors to construct social structure, person's attitudes, values, behavior patterns which are expected from other social members according to person's social status and position, and perceived and acquired through continuous interaction, communication, and leaning process.
This study investigates the behavioral characteristic difference of the container volumes of three ports-Gwangyang, Incheon, and Pyeongtaek-Dangjin. All series span the period January 2003 to December 2011. I first test whether the series are stationary or not. I can reject the null hypothesis of a unit root in each of the level variables and of a unit root for the residuals from the cointegration at the 5 percent significance level. I hitherto make use of error-correction model and find that Gwangyang port is the slowest in adjusting the short-run disequilibrium, whereas the adjustment speed of Incheon is much faster than that of Gwangyang. The impulse response functions indicate that container volumes increase only a little to the negative shocks in exchange rate, while they respond positively to the shocks in the business activity in a great magnitude and decay very slowly to its pre-shock level. meaning that the shocks last very long. The accumulative response to the exchange rate increase of 20 won per dollar and the 5 point industrial production increase is the smallest in Gwangyang, no more than a half of that of two ports. The intervention-ARIMA models also forecast that Gwangyang port will have much lower growth rate than Incheon and Pyeongtaek-Dangjin port in trading volumes.
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