• Title/Summary/Keyword: need for interaction

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Constructing Gene Regulatory Networks using Frequent Gene Expression Pattern and Chain Rules (빈발 유전자 발현 패턴과 연쇄 규칙을 이용한 유전자 조절 네트워크 구축)

  • Lee, Heon-Gyu;Ryu, Keun-Ho;Joung, Doo-Young
    • The KIPS Transactions:PartD
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    • v.14D no.1 s.111
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    • pp.9-20
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    • 2007
  • Groups of genes control the functioning of a cell by complex interactions. Such interactions of gene groups are tailed Gene Regulatory Networks(GRNs). Two previous data mining approaches, clustering and classification, have been used to analyze gene expression data. Though these mining tools are useful for determining membership of genes by homology, they don't identify the regulatory relationships among genes found in the same class of molecular actions. Furthermore, we need to understand the mechanism of how genes relate and how they regulate one another. In order to detect regulatory relationships among genes from time-series Microarray data, we propose a novel approach using frequent pattern mining and chain rules. In this approach, we propose a method for transforming gene expression data to make suitable for frequent pattern mining, and gene expression patterns we detected by applying the FP-growth algorithm. Next, we construct a gene regulatory network from frequent gene patterns using chain rules. Finally, we validate our proposed method through our experimental results, which are consistent with published results.

Interface for in-situ Authoring of Augmented Reality Contents on a Mobile Device Environment (모바일 환경 증강현실 콘텐츠 현장 저작 인터페이스)

  • Lee, Jeong-Gyu;Lee, Jong-Weon
    • The Journal of the Korea Contents Association
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    • v.10 no.7
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    • pp.1-9
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    • 2010
  • This paper introduces a difference between mobile Augmented Reality (AR) authoring and desktop AR authoring, and suggests an interface system that can be applied to in-situ authoring of AR contents on a mobile device. The mobile devices have enabled users to use the AR system anytime and anywhere. It is now necessary to create user's individualized context information using mobile devices on the spot. To author AR contents easily with mobile devices, we need to maximize the convenience of mobile systems, which have yet limitation. To do so, this paper suggests new interaction approaches that manage augmented contents using visual cues and other simple attribute settings. In addition, to solve the problem that users have to hold their mobile devices to track markers while authoring contents, this system enables users to author contents in environment based on captured images. This interface system also can make cooperation environment for more than one users to author contents. This paper verifies the usefulness of the proposed interface by user tests. The results of an analyzing users' comments show that the proposed interface is suitable for in-situ mobile authoring system.

The Auto-adhesion of Fingerprint Powders (지문 분말의 자착성(auto-adhesion)에 관한 연구)

  • Kim, Chae-Won;Cho, Hyeong-Woo;Lee, Sang-A;Song, Dong-Ha;Yu, Je-Seol
    • The Journal of the Korea Contents Association
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    • v.17 no.8
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    • pp.579-585
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    • 2017
  • Powder method is one of the most commonly used techniques for developing latent fingerprints on non-porous surfaces. While fingerprint powders become more diverse, there is no standard for the number of stroking a brush. For this reason, crime scene investigators need to stroke a brush as they try to figure out how much latent fingerprints are developed. Also, results vary from individual to individual. According to the combination of material and manufacturing, there are various results that powder particles hold together. It is called auto-adhesion which means the interaction between powder particles. This study showed auto-adhesion of 13 kinds of fingerprint powders expanding the number of stroking time. Consequently, some fingerprint powders had strong auto-adhesive property and others had weak auto-adhesion. Furthermore, the others did not change.

Interrater Reliability in the Content Analysis of Preparatory Information for Mechanically Ventilated Patients (인공호흡기 사용 환자들에게 제공된 예비적 정보에 대한 내용분석의 측정자간 신뢰도)

  • Kim Hwa-Soon
    • Journal of Korean Academy of Fundamentals of Nursing
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    • v.5 no.2
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    • pp.269-279
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    • 1998
  • In nursing research that the data is collected through clinical observation, analysis of clinical recording or coding of interpersonal interaction in clinical areas, testing and reporting interrater reliability is very important to assure reliable results. Procedures for interrater reliability in these studies should follow two steps. The first step is to determine unitizing reliability, which is defined as consistency in the identification of same data elements in the record by two or more raters reviewing the same record. Unitizing reliability have been rarely reported in previous studies. Unitizing reliability should be tested before progressing to the next step as precondition. Next step is to determine interpretive reliability. Cohen's kappa is a preferable method of calculating the extent of agreement between observer or judges because it provides beyond-chance agreement. Despite its usefulness, kappa can sometimes present paradoxical conclusions and can be difficult to interpret. These difficulties result from the feature of kappa which is affected in complex ways by the presence of bias between observers and by true prevalence of certain categories. Therefore, percentage agreement should be reported with kappa for adequate interpretation of kappa. The presence of bias should be assessed using the bias index and the effect of prevalence should be assessed using the prevalence index. Researchers have been reported only global reliability reflecting the extent to which coders can consistently use the whole coding system across all categories. Category-by-category reliability also need to be reported to inform the possibility that some categories are harder to use than others.

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Rheological Models for Describing Fine-laden Debris Flows: Grain-size Effect (세립토 위주의 토석류에 관한 유변학적 모델: 입자크기 효과)

  • Jeong, Sueng-Won
    • Journal of the Korean Geotechnical Society
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    • v.27 no.6
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    • pp.49-61
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    • 2011
  • This paper presents the applicability of rheological models for describing fine-laden debris flows and analyzes the flow characteristics as a function of grain size. Two types of soil samples were used: (1) clayey soils - Mediterranean Sea clays and (2) silty soils - iron ore tailings from Newfoundland, Canada. Clayey soil samples show a typical shear thinning behavior but silty soil samples exhibit the transition from shear thinning to the Bingham fluid as shear rate is increased. It may be due to the fact that the determination of yield stress and plastic viscosity is strongly dependent upon interstructrual interaction and strength evolution between soil particles. So grain size effect produces different flow curves. For modeling debris flows that are mainly composed of fine-grained sediments (<0.075 mm), we need the yield stress and plastic viscosity to mimic the flow patterns like shape of deposition, thickness, length of debris flow, and so on. These values correlate with the liquidity index. Thus one can estimate the debris flow mobility if one can measure the physical properties.

Prognostic Significance of HER-2/neu and Survival of Breast Cancer Patients Attending a Specialized Breast Clinic in Kolkata, Eastern India

  • Jana, Debarshi;Mandal, Syamsundar;Mukhopadhyay, Madhumita;Mitra, Debabrata;Mukhopadhyay, Sunit K.;Sarkar, Diptendra Kumar
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.8
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    • pp.3851-3855
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    • 2012
  • Introduction: The worldwide incidence of breast cancer has increased rapidly in recent years. The scenario of Eastern India is also showing the same trend. It is necessary to study the utility of HER-2/neu as a prognostic factor in breast cancer survival. However, there have not been detailed studies in this respect with the breast cancer patients of Eastern India. Thus this study was conducted. Materials and Methods: In this hospital-based study 86 breast cancer patients attending a breast clinic of a reputed institute of Eastern India and having invasive ductal carcinomas were observed for a period of 5 years after surgery. Associations between 5 years observed survival and status of ER, PR and HER-2/neu of the patients were critically evaluated. Results: There was statistically significant association between survival pattern for 5 years and the HER-2/neu status (p=0.00001). Better survival was observed for the patients with HER-2/neu negative tumors 67(100%) compared to HER-2/neu positive tumors 7(36.8%). Conclusions: There is strong interaction between survival and HER-2/neu expression of breast cancer patients. Thus the patients with HER-2/neu positive tumors need to be treated aggressively.

Types and Themes of Mobile Application Contents in Primary Science Learning Derived From Teachers' Perspectives (교사의 관점에서 제안된 초등 과학 영역의 모바일 앱 콘텐츠 유형 및 주제)

  • So, Hyo-Jeong;Yoon, Hye-Gyoung;Choi, Hyungshin
    • The Journal of the Korea Contents Association
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    • v.16 no.3
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    • pp.488-497
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    • 2016
  • Given the potential of mobile applications to create new learning opportunities beyond the prevalent use of digital textbooks and Internet lectures, this study aims to derive types and themes of mobile application content that can be effectively integrated with the school curricula. Twenty primary school teachers participated in this study that examines teachers' perceptions about the advantages and disadvantages of printed and digital textbooks' modality, the advantages and disadvantages of mobile learning, and the themes relevant to develop mobile applications. Findings indicate that it is necessary to develop activity-centered applications for vertical use rather than theme-centered applications for horizontal use. In addition, while most ideas derived from teachers center on multimedia access, there was lack of ideas that leverage the affordances of mobile devices for collaborative interaction and location-awareness. Lastly, to promote the diffusion of mobile learning in school environments, this study suggests the need to overcome teachers' epistemology that perceives mobilization against inquiry activities.

Identification of Advantages and Disadvantages Relative to Competitors of Politicians According to the Narrative Styles by Applying Voice Analysis (음성 분석을 통한 정치인들의 화법에 따른 경쟁자들 간의 상대적인 유·불리 규명)

  • Choi, Ji Hyun;Cho, Dong Uk;Lee, Bum Joo;Kim, Chan Jung;Jeong, Yeon Man
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.41 no.5
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    • pp.602-609
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    • 2016
  • In a smart society, politicians analyze the big data of voters to build a favorable political positions. In other words, a variety of digital footprints uploaded in SNS or Internet are used to set the election strategies and political directions. In comparison, it is difficult for voters to extract intention information about how politicians are performing a political acts. Therefore, it is important that voters need to analyze what intention of politicians are like for two way interaction between voters and politicians. For this, in this paper, we want to do the identification by analyzing IT technologies to narrative styles of politicians who pursue relative advantages or gains compared to other competitors. The experiments will be carried out to identify about what relative advantages compared to other competitors by narrative styles of next presidential candidates who are expected to run into the next presidential election by analyzing the usual audio interviews.

A Way to Smart Interface based on the IEEE 1451 Standards for Five-senses Information Device in Ubiquitous Environments (유비쿼터스 환경에서 오감 정보 장치를 위한 IEEE 1451 표준 기반의 스마트 인터페이스 방안)

  • Kim, Dong-Jin;Kim, Jeong-Do;Ham, Yu-Kyung;Lee, Jung-Hwan
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.9 no.2
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    • pp.339-346
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    • 2008
  • Ubiquitous computer can be interfaced with many several peripheral devices for information acquisition. Users should be able to easily use these devices without considering when these devices were interfaced, how to use these devices, and interoperability issues (such as plug and play, the installation of device drivers, and so on). Further, computers and their users need an interface technology that provides five-senses information (the recognition and expressions of the user) such that multimodal interaction can be enabled. In this paper, we proposed an IEEE 1451 standard that uses a smart interface standard for interfacing devices with ubiquitous computer. IEEE 1451 describes the property information of a transducer in the transducer electronic data sheet (TEDS). Further, by using the TEDS format, the interoperability between devices can be enabled by means of the plug-and-play function; it also makes the inconvenient installations of device drivers unnecessary.

Qualitative Study of Compliance with Nutritional Management in Colorectal Cancer Patient Undergoing Chemotherapy (수술 후 보조적 항암화학요법을 받는 대장암 환자의 일상영양관리 순응도에 대한 질적 연구)

  • Park, Heejung;Kil, Hyonson;Cho, Wookyoun
    • Korean Journal of Community Nutrition
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    • v.25 no.4
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    • pp.303-316
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    • 2020
  • Objectives: The nutritional status of cancer patients undergoing chemotherapy is closely related to the compliance of nutrition education. However, as chemotherapy is conducted repeatedly, compliance with nutrition management is lowered, leading to malnutrition. Malnutrition is related directly to the quality of life after surgery in cancer patients. Therefore, this study examined the factors related to compliance with nutrition management during chemotherapy. Methods: In this study, five subjects with colorectal cancer undergoing adjuvant chemotherapy were interviewed in-depth using the Giorgi study method. The contents of the nutrition education visits and in-depth interviews were transcribed in the language of the subject after recording, and the appropriateness of the data was improved by reflecting the subject's actions and facial expressions. Results: After conducting the in-depth interviews for each subject, the experience of the subject's diet and adjuvant chemotherapy was drawn into two domains, six elements, and 26 sub-elements. In the cognitive domain, the patients experienced physical and psychological changes, and the need for nutrition management was recognized by analyzing the dietary causes of the diseases. In the domain of practice, a knowing-doing gap was formed, unlike the patient's will. Factors that inhibited compliance with nutritional management included digestive problems, sensory changes, loss of appetite, and social interaction stress. Conclusions: Dietary management is very important for patients receiving periodic anticancer therapy, and step-by-step training and personal monitoring based on the chemotherapy order is necessary to maintain the patient's will and social and environmental support.