• Asian Pacific Journal of Cancer Prevention
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• v.14 no.8
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• pp.4621-4625
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• 2013

The purpose of this study was to construct a protein-protein interaction (PPI) network related to oral squamous cell carcinoma (OSCC). Each protein was ranked and those most associated with OSCC were mined within the network. First, OSCC-related genes were retrieved from the Online Mendelian Inheritance in Man (OMIM) database. Then they were mapped to their protein identifiers and a seed set of proteins was built. The seed proteins were expanded using the nearest neighbor expansion method to construct a PPI network through the Online Predicated Human Interaction Database (OPHID). The network was verified to be statistically significant, the score of each protein was evaluated by algorithm, then the OSCC-related proteins were ranked. 38 OSCC related seed proteins were expanded to 750 protein pairs. A protein-protein interaction nerwork was then constructed and the 30 top-ranked proteins listed. The four highest-scoring seed proteins were SMAD4, CTNNB1, HRAS, NOTCH1, and four non-seed proteins P53, EP300, SMAD3, SRC were mined using the nearest neighbor expansion method. The methods shown here may facilitate the discovery of important OSCC proteins and guide medical researchers in further pertinent studies.

• Proceedings of the KSRS Conference
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• 2007.10a
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• pp.616-619
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• 2007

Nowadays, urbanized area expands its boundary, and distribution of urbanized area is gradually transformed into more complicated pattern. In Korea, SMA(Seoul Metropolitan Area) has outstanding urbanized area since 1950s. But it is ambiguous whether urban distribution is clustered or dispersed. This study aims to show the way in which expansion of urbanized area impacts on spatial distribution pattern of urbanized area. We use quadrat analysis, nearest-neighbor analysis and fractal analysis to know distribution pattern of urbanized area in time-series urban growth. The quadrat analysis indicates that distribution pattern of urbanized area is clustered but the cohesion is gradually weakened. And the nearest-neighbor analysis shows that point patterns are changed that urbanized area distribution pattern is progressively changed from clustered pattern into dispersed pattern. The fractal dimension analysis shows that 1972's distribution dimension is 1.428 and 2000's dimension is 1.777. Therefore, as time goes by, the complexity of urbanized area is more increased through the years. As a result, we can show that the cohesion of the urbanized area is weakened and complicated.

• Journal of Intelligence and Information Systems
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• v.14 no.2
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• pp.193-206
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• 2008

Medical diagnosis can be considered a classification task which classifies disease types from patient's condition data represented by a set of pre-defined attributes. This study proposes a hybrid genetic algorithm based classification method to develop classifiers for multidimensional pattern classification problems related with medical decision making. The classification problem can be solved by identifying separation boundaries which distinguish the various classes in the data pattern. The proposed method fits a finite number of regional agents to the data pattern by combining genetic algorithms and local adaptive operations. The local adaptive operations of an agent include expansion, avoidance and relocation, one of which is performed according to the agent's fitness value. The classifier system has been tested with well-known medical data sets from the UCI machine learning database, showing superior performance to other methods such as the nearest neighbor, decision tree, and neural networks.

• International Journal of Computer Science & Network Security
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• v.23 no.8
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• pp.95-100
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• 2023

Due to Traffic accidents people faces health and economical casualties around the world. As the population increases vehicles on road increase which leads to congestion in cities. Congestion can lead to increasing accident risks due to the expansion in transportation systems. Modern cities are adopting various technologies to minimize traffic accidents by predicting mathematically. Traffic accidents cause economical casualties and potential death. Therefore, to ensure people's safety, the concept of the smart city makes sense. In a smart city, traffic accident factors like road condition, light condition, weather condition etcetera are important to consider to predict traffic accident severity. Several machine learning models can significantly be employed to determine and predict traffic accident severity. This research paper illustrated the performance of a hybridized neural network and compared it with other machine learning models in order to measure the accuracy of predicting traffic accident severity. Dataset of city Leeds, UK is being used to train and test the model. Then the results are being compared with each other. Particle Swarm optimization with artificial neural network (PSO-ANN) gave promising results compared to other machine learning models like Random Forest, Naïve Bayes, Nearest Centroid, K Nearest Neighbor Classification. PSO- ANN model can be adopted in the transportation system to counter traffic accident issues. The nearest centroid model gave the lowest accuracy score whereas PSO-ANN gave the highest accuracy score. All the test results and findings obtained in our study can provide valuable information on reducing traffic accidents.

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.28 no.2
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• pp.387-413
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• 1998

Image resampling is of particular interest in digital radiology. When resampling an image to a new set of coordinate, there appears blocking artifacts and image changes. To enhance image quality, interpolation algorithms have been used. Resampling is used to increase the number of points in an image to improve its appearance for display. The process of interpolation is fitting a continuous function to the discrete points in the digital image. The purpose of this study was to determine the effects of the seven interpolation functions when image resampling in digital periapical images. The images were obtained by Digora, CDR and scanning of Ektaspeed plus periapical radiograms on the dry skull and human subject. The subjects were exposed to intraoral X-ray machine at 60kVp and 70 kVp with exposure time varying between 0.01 and 0.50 second. To determine which interpolation method would provide the better image, seven functions were compared; (1) nearest neighbor (2) linear (3) non-linear (4) facet model (5) cubic convolution (6) cubic spline (7) gray segment expansion. And resampled images were compared in terms of SNR(Signal to Noise Ratio) and MTF(Modulation Transfer Function) coefficient value. The obtained results were as follows ; 1. The highest SNR value(75.96dB) was obtained with cubic convolution method and the lowest SNR value(72.44dB) was obtained with facet model method among seven interpolation methods. 2. There were significant differences of SNR values among CDR, Digora and film scan(P<0.05). 3. There were significant differences of SNR values between 60kVp and 70kVp in seven interpolation methods. There were significant differences of SNR values between facet model method and those of the other methods at 60kVp(P<0.05), but there were not significant differences of SNR values among seven interpolation methods at 70kVp(P>0.05). 4. There were significant differences of MTF coefficient values between linear interpolation method and the other six interpolation methods (P< 0.05). 5. The speed of computation time was the fastest with nearest -neighbor method and the slowest with non-linear method. 6. The better image was obtained with cubic convolution, cubic spline and gray segment method in ROC analysis. 7. The better sharpness of edge was obtained with gray segment expansion method among seven interpolation methods.

• International journal of advanced smart convergence
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• v.2 no.2
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• pp.40-42
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• 2013

Recent medical industry is an aging society and the application of national health insurance, with state-of-the-art research and development, including the pharmaceutical market is greatly increased. The nation's health care industry through new support expansion and improve the quality of life for the research and development will be needed. In addition, systemic administration of basic medical supplies, or drugs are needed, the drug at the same time managing how systematic analysis of pharmaceutical ingredients, based on data through the purchase of new medicines and pharmaceutical ingredients automatically classified by analyzing the statistics of drug purchases and the future a system that can predict a patient is needed. In this study, the drugs to the patient according to the component analysis and predictions for future research techniques, k-means clustering and k-NN (Nearest Neighbor) Comparative studies through experiments using the techniques employ a more efficient method to study how to proceed. In this study, the effects of the drugs according to the respective components in time according to the number of pieces in accordance with the patient by analyzing the statistics by predicting future patient better medical industry can be built.

• Water for future
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• v.28 no.2
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• pp.169-180
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• 1995

The cost of a looped pipe network is affected by a set of loop flows. The mathematical model for optimizing the looped pipe network is expressed in the optimal set of loop flows to apply to a stochastic optimization method. Because the feasible region of the looped pipe network problem is nonconvex with multiple local optima, the Modified Stochastic Probing Method is suggested to efficiently search the feasible region. The method consists of two phase: i) a global search phase(the stochastic probing method) and ii) a local search phase(the nearest neighbor method). While the global search sequentially improves a local minimum, the local search escapes out of a local minimum trapped in the global search phase and also refines a final solution. In order to test the method, a standard test problem from the literature is considered for the optimal design of the paralled expansion of an existing network. The optimal solutions thus found have significantly smaller costs than the ones reported previously by other researchers.

• Journal of Distribution Science
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• v.16 no.1
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• pp.87-99
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• 2018

Purpose - The Export Infrastructure Strengthening Program(EISP) is a project to expand exports of agri-food products through providing customized export information to food distribution companies and supporting overseas information activities. A total of 39.6 billion won was provided by 2016. So, the purpose of this study is to analyze whether EISP is effective for expanding exports of agri-food products. Research design, data, and methodology - A simple average difference between the export performance of the policy beneficiaries and the non-policy beneficiaries can be biased if the export capacity or inherent characteristics of the enterprise are not taken into consideration. In order to solve the problem of such a bias, the propensity score matching(PSM) method has been employed in this study. PSM is a method of converting the characteristics of an export company into an index through logit analysis and then reducing the matching to one dimension to improve the accuracy of the performance measurement. Results - The balancing test was conducted to determine how the characteristics of the policy beneficiary group and the matched policy non-beneficiary group corresponded to each other. As a result of the test, we could not reject the null hypothesis that there was no difference between the two groups, so that after the matching, the two groups were similar and the explanatory variables were well controlled. Using the nearest neighbor matching with propensity score estimating through logit analysis, we estimated average treatment effect on the treated(ATT). The food companies participating the EISP had the effect of increasing the exports of $ 5.88 million. As a result, the number of export contracts increased by 11.77, the number of exporting countries by 7.52, the number of export items by 47.51, and the number of buyers' consultation by 3.50. And overseas marketing expenses increased by 35.92 million won. Except for the number of export contracts, other export performance results showed statistically significant results. Conclusions - As the EISP has a positive effect on the expansion of agro-food exports, efforts should be made to find out the limitations or problems of the policy in the future and to make a greater contribution to the increase of exports.