• Journal of Preventive Medicine and Public Health
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• v.40 no.2
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• pp.95-101
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• 2007

Focusing on complex diseases of public health significance, strategic issues regarding the on-going Korean Genome Cohort were reviewed: target size and diseases, measurements, study design issues, and follow-up strategy of the cohort. Considering the epidemiologic characteristics of Korean population as well as strengths and drawbacks of current research environment, we tried to tailor the experience of other existing cohorts into proposals for this Korean study. Currently 100,000 individuals have been participating the new Genome Cohort in Korea. Target size of de novo collection is recommended to be set as between 300,000 to 500,000. This target size would allow acceptable power to detect genetic and environmental factors of moderate effect size and possible interactions between them. Family units and/or special subgroups are recommended to parallel main body of adult individuals to increase the overall efficiency of the study. Given that response rate to the conventional re-contact method may not be satisfactory, successful follow-up is the main key to the achievement of the Korean Genome Cohort. Access to the central database such as National Health Insurance data can provide enormous potential for near-complete case detection. Efforts to build consensus amongst scientists from broad fields and stakeholders are crucial to unleash the centralized database as well as to refine the commitment of this national project.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.19 no.2
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• pp.221-227
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• 2019

It has long been known that weapon target assignment (WTA) problem is NP-hard. Nonetheless, an exact solution can be found using Brute-Force or branch-and bound method which utilize approximation. Many heuristic algorithms, genetic algorithm particle swarm optimization, etc., have been proposed which provide near-optimal solutions in polynomial time. This paper suggests polynomial time algorithm that can be obtain the optimal solution of WTA problem for the number of total weapons k, the number of weapon types m, and the number of targets n. This algorithm performs k times for O(mn) so the algorithm complexity is O(kmn). The proposed algorithm can be minimize the number of trials than brute-force method and can be obtain the optimal solution.

• The Journal of the Acoustical Society of Korea
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• v.38 no.1
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• pp.120-127
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• 2019

Passive source depth discrimination has been studied for decades since the source depth can be used for discriminating whether the target is near the surface or submerged. In this thesis, an algorithm for source depth discrimination is proposed based on CIR (Channel Impulse Response) from target-radiated noise (or signal). In order to extract CIR without a known source signal, Ray-based blind deconvolution is used. Subsequently, intersections of CIR pattern, which is characterized by ray arrival time difference, is utilized for discriminating source depth. The proposed algorithm is demonstrated through numerical simulation in ocean waveguide, and verified via the experimental data.

• Asian-Australasian Journal of Animal Sciences
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• v.28 no.11
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• pp.1532-1536
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• 2015

To verified the target genes of miR-34c, bioinformatics software was used to predict the targets of miR-34c. Three possible target genes of miR-34c related to spermatogenesis and male reproductive development: zinc finger protein 148 (ZNF148), kruppel-like factor 4 (KLF4), and platelet-derived growth factor receptor alpha (PDGFRA) were predicted. Then, the expression of miR-34c and its target genes were detected in swine testicular tissue at different developmental stages by quantitative polymerase chain reaction. The results suggested that the expression of PDGFRA has the highest negative correlation with miR-34c. Then immunohistochemical staining was done to observe the morphology of swine testicular tissue at 2-days and 3, 4, 5-months of age, which indicated that PDGFRA was mainly expressed in the support cells near the basement membrane during the early development stages of testicular tissue, but that the expression of PDGFRA was gradually reduced in later stages. Therefore, western blot analyzed that the highest expression of PDGFRA was generated in 2-days old testicular tissues and the expression levels reduced at 3 and 4-months old, which correlated with the results of immunohistochemical staining. In conclusion, PDGFRA is a target gene of miR-34c.

• Journal of Advanced Navigation Technology
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• v.19 no.5
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• pp.403-410
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• 2015

ADS-B can provide high accurate position information and faster update rate than Radar system and it is a technique that can supplement or replace the Radar. Recently ADS-B has been applied to the actual aircraft operation because to increase air transportation traffic and required to high accurate surveillance. In this study, we surveyed analysis of position deviation distribution analysis and received actual ADS-B trajectory data for conformed precise surveillance on the near airport area using ADS-B message. For that, we received the precision instrument approach ADS-B trajectory data using instrument landing system, and can analyse about target deviation distribution on the final approach segment about precision instrument approach. The result of analysis is mean distance of target deviation -0.04 m and standard deviation 6.71 m on between ADS-B target and extended runway centerline. Also that is to conformed the ADS-B message trajectory available to provide relatively exact surveillance information.

• 제어로봇시스템학회:학술대회논문집
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• 1992.10a
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• pp.141-146
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• 1992

Joint probabilistic data association filter(JPDAF) for multi-target tracking was developed for real-time implementation, while it abandoned an algorithm for track initiation. In this paper, we propose three features for track initiation that can be adapted to the JPDA filter. In addition, with the proposed approaches, the performance of track maintenance is evaluated in the case of tracks being near. To eliminate the abundant false tracks, we exploit the simple method using the state error covariances. Simulations are performed to demonstrate the efficiency of the proposed approaches.

• Proceedings of the Korean Society for Technology of Plasticity Conference
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• 2000.04a
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• pp.141-145
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• 2000

A systematic method to find the optimal blank shape for sheet forming is proposed by coupling the numerical simulation technique. A weighted parameter was introduced in order to simplify the multi-variable optimization problem to a single-variable problem. The proposed method has been applied to the blank design of drawing processes to obtain the near-net shape within the required error bound after forming, Excellent results have been obtained between the numerical results and the target contour shapes. Through the investigation the proposed systematic method for optimal blank design is found to be effective in the practical forming processes

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.3 no.1
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• pp.5-25
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• 2009

In recent years the popularity of multi-hop wireless networks has been growing. Its flexible topology and abundant routing path enables many types of applications. However, the lack of a centralized controller often makes it difficult to design a reliable service in multi-hop wireless networks. While packet routing has been the center of attention for decades, recent research focuses on data discovery such as file sharing in multi-hop wireless networks. Although there are many peer-to-peer lookup (P2P-lookup) schemes for wired networks, they have inherent limitations for multi-hop wireless networks. First, a wired P2P-lookup builds a search structure on the overlay network and disregards the underlying topology. Second, the performance guarantee often relies on specific topology models such as random graphs, which do not apply to multi-hop wireless networks. Past studies on wireless P2P-lookup either combined existing solutions with known routing algorithms or proposed tree-based routing, which is prone to traffic congestion. In this paper, we present two wireless P2P-lookup schemes that strictly build a topology-dependent structure. We first propose the Ring Interval Graph Search (RIGS) that constructs a DHT only through direct connections between the nodes. We then propose the ValleyWalk, a loosely-structured scheme that requires simple local hints for query routing. Packet-level simulations showed that RIGS can find the target with near-shortest search length and ValleyWalk can find the target with near-shortest search length when there is at least 5% object replication. We also provide an analytic bound on the search length of ValleyWalk.

• Korean Institute of Interior Design Journal
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• v.21 no.2
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• pp.174-185
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• 2012

The purpose of this study is to suggest planning strategy of tenant mix for UEC based on the final result of tenant mix analysis of five different research cases. The following is the comprehensive explanation about the result of tenant mix planning strategy for UEC currently in operation and when planning a new facility. First, overall research cases in this study show the tendency of following an old tradition, which stresses direct sales focusing on retail and dining adaptation. In order to compensate the defect, it is suggested to adopt new type of tenants with the functional mix of retail and dining with entertainment rather than decreasing the proportion of retail and dining tenant and increasing it of entertainment tenant. Second, the floorplan of UEC should adopt racetrack or circuit form that can stimulate shoppers' circular movement so to expose them to as much tenants as possible. Service consumption mode related tenants are required to place on the side or the edge of UEC, while retail consumption mode related tenants should be planned in the center. Among dining consumption mode related tenants, impulse dining tenants like a coffee shop should be placed at the turning point or at the end of the pathway, destination tenants like a restaurant and a food court, on the other hand, is needed to be placed in the center of the space. In case of Entertainment related tenants, destination tenants like bookstore or multiplex should also be placed at the end of the pathway, and on the way to those tenants, it is required to place general tenants that can share target customers with them. On the contrary, game center or record shop like tenants that can stimulate impulse sales should be placed on the visitor's main move or near the other destination tenants. Third, anchor tenants play an important role in gathering people to the UEC, and then induce them to visit the other tenants that are located near the anchors. Thus it is suggested to plan to place general tenants on the same floor as anchor tenants are placed so they can share the characteristics of target customers which create synergy effect.

• Phonetics and Speech Sciences
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• v.1 no.3
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• pp.3-18
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• 2009

Do loanword properties emerge in the acquisition of a foreign language and if so, how? Classic studies in adult language learning assumed loanword properties that range from near-ceiling to near-chance level of appearance depending on speech proficiency. The present research argues that such variations reflect different phonological types, rather than speech proficiency. To investigate the difference between learner speech and loanword phonology, the current research analyzes the speech data from five different proficiency levels of 92 Korean speakers who read 19 pairs of English words and sentences that contained loanwords. The experimental method is primarily an acoustical one, by which the phonological cause in the loanwords (e.g., the insertion of [$\Box$] at the end of the word stamp) would be attested to appear in learner speech, in comparison with native speech from 11 English speakers and 11 Korean speakers. The data investigated for the research are of segment deletion, insertion, substitution, and alternation in both learner speech and the native speech. The results indicate that learner speech does not present the loanword properties in many cases, but depends on the types of phonological causes. The relatively easy acquisition of target pronunciation is evidenced in the cases of segment deletion, insertion, substitution, and alternation, except when the loanword property involves the successful command of the target phonology such as the de-aspiration of [p] in apple. Such a case of difficult learning draws a sharp distinction from the cases of easy learning in the development of learner speech, particularly beyond the intermediate level of proficiency. Overall, learner speech departs from loanword phonology and develops toward the native speech value, depending on phonological contrasts in the native and foreign languages.