• Archives of Pharmacal Research
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• v.20 no.6
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• pp.519-524
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• 1997

Steroid $9{\alpha}$-hydroxylase is an enzyme found in nocardioform microorganisms which can utilize steroids as a sole carbon source. After fractional centrifugation of the cell homogenates, the enzyme activity in Nocardia and Rhodococcus was found in cytoplasmic membrane fraction. On the contrary, Mycobacterium had its 9.alpha.-hydroxylation activity in cytosolic fraction. To characterize the enzyme in these microorganisms, several potential inhibitors of 9.alpha.-hydroxylase were tested and the cofactor requirement for the same enzyme was also examined. The inhibitory effect of ferrous ion chelators indicated involvement of iron containing proteins in the 9.alpha.-hydroxylase system. On the other hand, metyrapone, an inhibitor known to be specific for cytochrome P450 interfered with the enzyme in Mycobacterium, but didn't inhibit the enzyme activity in Nocardia and Rhodococcus. While the $9{\alpha}$-hydroxylase system in Nocardia and Rhodococcus required NADPH, NADH was required as an election donor in Mycobacterium.

• Bulletin of the Korean Chemical Society
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• v.12 no.1
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• pp.17-22
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• 1991

Fourier transform infrared spectroscopy has been applied to the characterization of titania supported molybdena. The equilibrium adsorption method seemed to produce molybdena species homogeneously dispersed on the support. Even under an oxidizing environment, molybdena species appeared to be able to possess coordinatively unsaturated $Mo^{5+}$ ions owing to the natures of TiO$_2$, i.e. oxygen deficiency and permeability toward oxygen diffusion. At the initial stage of reduction, the terminal double bond oxygen ( Mo=O ) seemed to be removed, generating presumably $Mo^{4+}$. The carbonyl bands at 2198 and 2190 $cm^{-1}$ observed after CO exposure were attributed to the $Mo^{5+}{\cdots}CO\;and\;Mo^{4+}\;{\cdots}CO$ complexes, respectively, while the band pair at 2136 and 2076 $cm^{-1}$ to $Mo^{4+}(CO)_2$.

• Journal of the Korean Magnetic Resonance Society
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• v.23 no.1
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• pp.33-39
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• 2019

Studies on the interactions of proteins with partner molecules at the atomic resolution are essential for understanding the biological function of proteins in cells and for developing drug molecules. Solution NMR spectroscopy has shown remarkably useful capability for investigating properties on the weak to strong intermolecular interactions in both diluted and crowded solution such as cell lysates. Of note, the state-of-the-art in-cell NMR method has made it possible to obtain atomistic information on natures of intermolecular interactions between target proteins with partner molecules in living cells. In this mini-review, we comprehensively describe the several technological advances and developments in the in-cell NMR spectroscopy.

• The Bulletin of The Korean Astronomical Society
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• v.44 no.1
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• pp.73.3-73.3
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• 2019

A Korean VLBI Network $1^{st}$ generation key science program, the Interferometric Monitoring of Gamma-ray Bright AGNs (iMOGABA) program has revealed various natures of gamma-ray flares in active galactic nuclei (AGNs). Here in this presentation, we would like to introduce a new candidate of KVN $2^{nd}$ generation key science program, so called, the AiMOGABA (Astrometric iMOGABA), aiming at studying a wondering radio core effect of relativistic jets from AGNs with high resolution VLBI astrometric monitoring of high-energy bursting AGNs with KVN as well as a Australian millimeter radio telescope MOPRA. The introduction will include the current scientific highlights of the iMOGABA, and the overview of the AiMOGABA.

• Proceedings of the PSK Conference
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• 2002.10a
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• pp.335.2-335.2
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• 2002

Despite the use of antibiotics and vaccines, Streptococcus pneumoniae remains a serious cause of morbidity and morality in human. In this study, pathogenic and immunological natures of alcohol dehydrogenase (ADH) in S. pneumoniae were elucidated. In vitro cytotoxicity test determined by lactate dedydrogenase release from A549 cells revealed that adh mutation significantly reduced cytotoxicity although in vivo intraperitoneal challenge of the adh mutant to BALB/C mouse exhibited marginal increase of survival time than the wild type. (omitted)

• Journal of Korean Academy of Nursing
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• v.28 no.2
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• pp.498-509
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• 1998

The phrases such as elders' powerless soliloquy or stammering and their positions unadjusted to the real world are, so far, one of negative views on elder's reminiscences. In other words, it means that elders can get psychological consolation from the getting themselves absorbed in their past. The starting point of this study is, however, that elders' reminiscence are their own mode of the existence. This dissertation is studied through Van Manen's phenomenological research method. The aim of this study is to examine the nature of Korean elders' reminiscences by both observing and describing the reminiscing content in everyday life of elders. The research participants consist of the ten elders who are community elders, hospitalized elders and nursing home residents. The period of the research is about a year from Jan., 1996 to Feb., 1997. The results of this study are as follows : The natures of elders' reminiscences are the regrecting on their life, mitigating the regrects, the confirmation of the powers and the confirmation of their life's mark. The regrecting on their life is the starting point of elders's reminiscences. Elders have tried to examine their life through reflection on their life that they did not live good life as son and daughter for parents and as parents for children and that they have foolishly lived, on dream that they did not come true, on their learning that they did not unsatisfied. But elders mitigate the regrects. They have felt their limitations of power in the conflict of human relation, the economic matter and the difficult predicament, and have finally accepted their life as it is by conquesting from their tenacity. It is dynamically found that both the regrecting on their life and mitigating of the regrection. And they pursuit the powers. It means the pursuit of the vital powers, the vigorous powers and the competency. Elders have pursued their vitality, vigor and competency through their reminiscences and have wanted to be recognised by others as a powerful being. These have dynamic and compounded aspects. The confirmation of their life's mark refer to through their own situation of health, condition, children, neighbourhood and doing their duty as a human. Elders have confirmed the present value of their being through the reflecting the present, past self, other men around themselves, children, neighborhood and the doing their human duty as a good men. Therefore the results of this study can offer new view on the elders' reminiscences that we have to understand them as a process as what they are, escaping from the simple logic that elders' reminiscence have a positive or a negative effects. Also, this study which have examined the natures of Korean elders' reminiscences can cast a new light on elders' nursing proper for Korean culture.

• Journal of Science of Art and Design
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• v.6
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• pp.119-139
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• 2004

The intention of the research is to look into the form reflecting the spiritual image due to Oriental aesthetic from a realistic point of view. In this regard, I will pay attention to examining the process from figurative perspectives, in which painting image by subject acquires the beauty of form. Of the main subjection this paper, figure is an image itself appearing in painting. At this point, I will attempt to show how the meaning and value of image have been interpreted and judged on the aesthetic standard in Oriental painting in particular. For this process, I generalize the conception of the image as 'figure' and through this I will reconsider the standard of understanding and the value of perception regarding painting images on the method which are more applicable to the expressions of Oriental painting. The reason why I try to find out the true nature of images in Oriental painting from a figurative viewpoint is to convert a conventional sense of value which recognizes the images of Oriental painting only as results of idealism, into more practical field. If the true nature of Oriental painting is fixed and restricted to natures of idealism, any productive development and any changes in form for future couldn't be expected at all. In fact, what the ideological and aesthetic values of art suggest is clearly a proof of real art form. However, it is not a hard thing to prospect that only a superficial idealism will be ceaselessly produced, while the practical study about aesthetic values, meaningful results of painting expressions, is totally ignored, if ideology itself is used as criteria to judge the identity of it or if only the idealistic aesthetic values are emphasized while any clue to show a real existence of oriental paintings is not certain. Actually, nobody can deny the fact that interests about real natures regarding art expressions have been relatively ignored while armed with mental ideology for esthetic view of oriental painting in traditionalism Therefore, it is clear that 'spiritual status' itself can generate any form. Traditionally, in the Orient, the standard of judging a real value of things, which put a focus on a spiritual view of value rather than on a materialistic view of it, has been vaguely positioned the identity of images in painting As a result, the aesthetic convention has finally committed to an error that for images of oriental painting, ideological criteria like so called spiritualism are applied as a judging way, and esthetic meanings and values of real painting are considered as strategic results and spiritual intentions.

• Korean Journal of Environmental Agriculture
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• v.18 no.2
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• pp.116-121
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• 1999

Tree leaves have been used as the passive sampler to measure lipophilic PAHs in the atmosphere. This is a convenient and economical method in case of sampling at many regions including the remote places that are not supplied with electric power. But poor results can be obtained if samples are collected carelessly or PAHs concentrations are calculated on the basis of wrong natures of tree leaves. This study was performed to avoid the errors of interpretation that can be induced by these problems when tree leaves are used as a passive sampler of PAHs. Conclusions have been reached as follows: 1) The correlativity was low among the water content, the lipid content, the dry weight and the area of four kinds of tree leaves. According to this, PAHs concentrations calculated per wet weight, dry weight, lipid content and area of tree leaves differed. Therefore, same unit shoud be used to describe concentrations of the pollutants when PAHs concentrations deposited on leaves from atmosphere in the different regions are compared. It is better to decribe the unit as PAHs concentrations per dry weight of leaves for comparison with other data because almost researcher make use of this unit, and the range of fluctuation of the dry weights in several natures of tree leaves was relatively little during growing seasons. 2) Although four kinds of trees(Pinus Koraiensis, Ginkgo biloba, Evodia daniellii, Kalopanax pictus) had been grown at the same place, PAHs concentrtions deposited on leaves differed respectively. Therefore PAHs concentrations deposited on different kinds of tree leaves should not be compared. It is better to make use of pine needles as the sample because pine trees grow almost over the world, and it is able to collect their samples in winter.

• Korean Journal of Construction Engineering and Management
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• v.6 no.4 s.26
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• pp.80-90
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• 2005

Activity durations retain probabilistic and stochastic natures due to diverse factors causing the delay or acceleration of activity completion. These natures make the final project duration to be a random variable. These factors are the major source of financial risk. Extending the Stochastic Project Scheduling Simulation system (SPSS) developed in previous research; this research presents a method to estimate how the final project duration behaves when activity durations change randomly. The final project cost is estimated by considering the fluctuation of indirect cost, which occurs due to the delay or acceleration of activity completion, along with direct cost assigned to an activity. The final project cost is estimated by considering how indirect cost behaves when activity duration change. The method quantifies the amount of contingency to cover the expected delay of project delivery. It is based on the quantitative analysis to obtain the descriptive statistics from the simulation outputs (final project durations). Existing deterministic scheduling method apply an arbitrary figures to the amount of delay contingency with uncertainty. However, the stochastic method developed in this research allows computing the amount of delay contingency with certainty and certain degree of confidence. An example project is used to illustrate the quantitative analysis method using simulation. When the statistical location and shape of probability distribution functions defining activity durations change, how the final project duration and cost behave are ascertained using automated sensitivity analysis method

• Journal of Korean Society for Atmospheric Environment
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• v.18 no.E2
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• pp.97-106
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• 2002

The purpose of this study was to quantitatively estimate the washout removal efficiencies of criteria air pollutants such as SO$_2$, TSP, PM10, CO, NO$_2$, and O$_3$corresponding to the amounts and durations of precipitation. The removal patters by washout were studied with air pollutants data and the corresponding precipitation data in Seoul, Korea during the periods of 1990 to 1999. In addition, washout patterns were classified into four seasons and four time Bones, i.e., night, morning, afternoon, and evening. In this study, natures of air pollutants by sequential precipitation were also intensively studied by examining the linear relationships between removal efficiencies and the amounts and durations of precipitation for each pollutant. The results of this study showed that SO$_2$, TSP, and O$_3$were rapidly removed by initial precipitation; however, NO$_2$was slowly removed 2-hour after precipitation. Both CO and PM10 were weakly removed by washout and their removal patters showed to be irregular.