• Journal of the Korean Chemical Society
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• v.56 no.6
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• pp.679-691
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• 2012

New series of metal complexes of Co(II), Ni(II), Cu(II), Zn(II), Pd(II) and Pt(II) with 4-(p-chlorophenyl)-1-(pyridin-2-yl)thiosemicarbazide (HCPTS) have been synthesized and characterized by elemental analyses, magnetic moment, spectra (IR, UV-Vis, $^1H$ NMR, mass and ESR) and thermal studies. The IR data suggest different coordination modes for HCPTS which behaves as a monobasic bidentate with all metal ions except Cu(II) and Zn(II) which acts as a monobasic tridentate. Based on the electronic and magnetic studies, Co(II), Cu(II), Pd(II) and Pt(II) complexes have square - planner, Ni(II) has mixed stereochemistry (tetrahedral + square planar), while Zn(II) is tetrahedral. Molar conductance in DMF solution indicates the non-ionic nature of the complexes. The ESR spectra of solid copper(II) complex show $g_{\parallel}$ (2.2221) > $g_{\perp}$ (2.0899) > 2.0023 indicating square-planar structure and the presence of the unpaired electron in the $d_x2_{-y}2$ orbital with significant covalent bond character. The thermal stability and degradation kinetics of the ligand and its metal complexes were studied by TGA and DTA and the kinetic parameters were calculated using Coats-Redfern and Horowitz-Metzger methods. The complexes have more antibacterial activity against some bacteria than the free ligand. However, the ligand has high anticancer activities against HCT116 (human colon carcinoma cell line) and HEPG2 (human liver hepatocellular carcinoma cell line) compared with its complexes.

• Journal of Korean Academy of Nursing
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• v.45 no.3
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• pp.439-448
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• 2015

Purpose: The purpose of this study was to examine validity and reliability of Webel and colleagues'HIV Self-Management Scale when used with a Korean sample. Methods: The original 20-item HIV Self-Management Scale was translated into Korean using translation and back-translation. Nine HIV nurse experts tested content validity. Principal component analysis (PCA) and confirmatory factor analysis (CFA) of data from 203 patients was used to test construct validity. Concurrent validity was evaluated using correlation with patients'self-rating as a "mart patient"measured using a visual analogue scale. Internal consistency was tested by Cronbach' alpha coefficients. Results: All items were rated as having satisfactory content validity. Based on PCA and consideration of conceptual meaning, a three-factor solution was selected, explaining 48.76% of the variance. CFA demonstrated the adequacy of the three-domain structure of the construct HIV self-management: daily self-management health practices, social support and HIV self-management, and chronic nature of HIV self-management. Goodness-of-fit indices showed an acceptable fit overall with the full model (${\chi}^2/df_{(164)}=1.66$, RMSEA=0.06, SRMR=0.05, TLI=0.91, and CFI=0.92). The Korean version of the HIV Self-Management Scale (KHSMS) was significantly correlated with patients'self-rated smart patient (r=.41). The subscale Cronbach' alpha coefficients ranged from .78 to .81; alpha for the total scale was .89. Conclusion: The KHSMS provides a valid and reliable measure of self-management in Korean patients with HIV. Continued psychometric testing is recommended to provide further evidence of validity with this population.

• Korean Journal of Materials Research
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• v.24 no.11
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• pp.639-643
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• 2014

Hydrophilic $SiO_2$ layers were obtained by the atmospheric-pressure plasma treatment. Superhydrophobic $SiO_2$ layers were first deposited by the electrospray deposition method. The electrospunable solution that was prepared based on the solgel method was sprayed on Si (100) substrates. The surface of the electrosprayed $SiO_2$ layers consisted of the agglomeration of nano-sized grains, which led to a very high roughness and revealed a very high contact angle to water droplets over $162^{\circ}$. After having been exposed to the atmospheric $Ar/O_2$ plasma, the observed superhydrophobicity of the $SiO_2$ layers were greatly changed: a dramatic variation of the water contact angle from $162^{\circ}$ to $3^{\circ}$, namely realization of superhydrophillicity. Interestingly, the surface microstructure was almost preserved. According to the XPS analysis, it is more likely that thanks to the plasma exposure, the surface of $SiO_2$ layers will be cleaned in terms of organic species that are hydrophobic-inducing, consequently leading to the hydrophilic nature observed for the plasma-exposed $SiO_2$ layers.

• KSBB Journal
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• v.30 no.6
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• pp.291-295
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• 2015

The limited productivity of natural shell matrix proteins has hampered the investigation of their biochemical properties and practical applications, although biominerals in nature obtained by organic-inorganic assemblies have attractive mechanical and biological properties. Here, we prepared a vector for the expression of a fusion protein of a shell matrix protein from Pinctada fucata (named as GRP_BA) with the GRGDSP residue. The fusion protein of BA-RGD was simply produced in E. coli and purified through sequential steps including the treatment with $CaCl_2$ and EDTA solution for cell membrane washing, mechanical cell disruption and the application of non-ionic surfactant of Triton X-100 for BA-RGD inclusion body washing. The production yield was approximately 60 mg/L, any other protein band was not observed in SDS-PAGE and it was estimated that above 97% endotoxin was removed compared to the endotoxin level of whole cell. This study showed this simple and easy purification approach could be applied to the purification of BA-RGD fusion protein. It is expected that the protein could be utilized for the preparation of biominerals in practical aspects.

• Journal of the Korean Society of Industry Convergence
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• v.20 no.5
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• pp.351-357
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• 2017

Growing plant in potting media without soil is known as Soilless cultivation. This method is used mostly in greenhouse cultivation to increase horticultural commodities production. Peat moss is commonly utilized as potting media substrate because of its characteristic. However, peat moss price is high because of the quantity of peat moss in nature has been decreased. Recently, most of the research is conducted to find the alternative growing medium to cultivate horticulture plant in potting media. Perlite and rice husk ash were mentioned that had a potent as alternative growing media for seasonal plants to increase agriculture production due to the lack of production area. This study aimed to determine the effect of using different substrate and growth performance of chili. The method used was the soilless cultivation. The chili was planted in the pot with perlite media, rice husk ash media, and peat moss media. The chili was measured after 65 days after planting. The result showed that rice husk ash and perlite were more potentials in chili growth performance than peat moss. Rice husk ash had the significant result of plant height. While, Perlite effect on root length, plant weight, leaf length, and stem diameter. The best alternative for cultivation chili without substrate based on this research was perlite then rice husk ash and peat moss.

• The Journal of Korean Medicine
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• v.27 no.4
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• pp.174-181
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• 2006

Objective : Based on the immunological dysfunction in RA and the immunological feature of Clematis mandshurica Maxim. herbal acupuncture solution (CM-HAS), this study examined whether subcutaneous (s.c.) administration of CM-HAS has anti-inflammatory effects on adjuvant arthritis (AA) in the rat. Methods : Complete Freund's adjuvant was used to induce AA in rats. Secondary paw swelling of AA rats was measured, and polyarthritis index was scored. The administration of CM-HAS (2, 5, 10 mg/kg) to the Sinsu-hyul (BL 23) acupuncture point subcutaneously (s.c.) inhibited the inflammatory response and restored the weight of body and immune organs of AA rats. In this study. inhibitory effect of CM-HAS on cyclooxygenase-2 (COX-2) was evaluated. The plant material selected for this study has been used in Korean medicine for the treatment of various diseases that are considered as inflammatory in nature, e.g. asthma, arthritis, rheumatism, fever, edema, infections, snakebite and related inflammatory diseases. Results : There were significant secondary inflammatory reactions in AA rats, accompanied with the simultaneous decrease of body and immune organs weight. The administration of CM-HAS (2, 5, 10 mg/kg, s.c.) improved the above changes significantly. CM-HAS showed inhibitory activity against COX-2, which supports their traditional uses. In this study, aspirin and indomethacin were used to contrast with CM-HAS as the COX-2 inhibitors. Conclusion: The findings of this study may explain at least in part why CM-HAS has been traditionally used for the treatment of inflammatory conditions in traditional Korean and Chinese medicine.

• Korean Institute of Interior Design Journal
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• v.24 no.1
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• pp.12-22
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• 2015

When it comes to the architecture design, Kuma Kengo rejects a strong and violent subject-centered position and advocates the design that is object-oriented. As can be seen in 'gentle architecture', 'three lows principle', 'natural architecture', and 'connecting architecture', he clearly expresses the objective nature of architecture design in those terms. In this respect, the purpose of this study is to make a close inquiry into the meaning, effect and characteristics of objectivity. In particular, we try to identify the contents of 'impure architecture', which has a clear ambivalence to be an instrumental expression strongly settled in the objectivity, in an aesthetic standpoint. To do that, we systemized the concept of mimesis and the theory of subversive appropriation by Walter Benjamin and Theodor Adorno in to a frame of interpretation. By systemizing translation, subversion, verbalization and the dialectic structure of the aesthetics of negation, we interpreted the features of his works as an objective work and 'impure architecture'. His objectivity leads the situation by subversively appropriating the inherent elements of architectural conditions based on a dialectic solution in which inquiries on logical and scientific materials have played a critical role. Above all, through all these processes, he tried to suggest a language as a new technique for materials and structures. Ultimately, we could find out that this object oriented design sublates a subject oriented way that is monolithic and repetitive regardless of objects. Rather, it is a way that is effective in creating a new way of design by making a different approach to a new object rather unfamiliarly, yet deeply.

• Korean Institute of Interior Design Journal
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• v.23 no.3
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• pp.39-47
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• 2014

This study was initiated by the fact that modern architecture caused the loss of placeness by seeing place with wrong interpretation and method and provided people with a phenonenon of separation between the depth of experience and honesty. As a solution for such problems, this study intended to suggest a direction through an analysis on the works of Geoffrey Bawa who was recognized as 'a genius of place' and the investigation on the place characteristics of his representative work 'Lunuganga'. Its process was as follows; First, this study explored the characteristics of the place, Sri Lanka, which was the background of his architectures, to see its impact on his life and architecture. Second, based on his representative works of each period and the contents that he mentioned in literature, the general characteristics appearing in his architectures were identified. Third, through an analysis on the work, Lunuganga, the place characteristics appearing in his architectures were investigated. Through such process, it could be recognized that Geoffrey Bawa's architectures reveal the place characteristics as nature, place characteristic as journey and stay, and place characteristic as sense. In this study, it could be verified that place was integrated and applied to Geoffrey Bawa's architectures through the above characteristics and the spaceness was manifested. Through this, this study intended to suggest an orientation for the above problems.

• Bulletin of the Korean Chemical Society
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• v.31 no.8
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• pp.2170-2174
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• 2010

The surfaces of $TiO_2$ and ZnO nanoparticles have been modified by gold (Au) nanoparticles by a reduction method in solution. Their interfacial electronic structures and optical absorptions have been studied by depth-profiling X-ray photoelectron spectroscopy (XPS) and UV-vis absorption spectroscopy, respectively. Upon Au-modification, UV-vis absorption spectra reveal a broad surface plasmon peak at around 500 nm. For the as-prepared Au-modified $TiO_2$ and ZnO, the Au $4f_{7/2}$ XPS peaks exhibit at 83.7 and 83.9 eV, respectively. These are due to a charge transfer effect from the metal oxide support to the Au. For $TiO_2$, the larger binding energy shift from that (84.0 eV) of bulk Au could indicate that Au-modification site of $TiO_2$ is different from that of ZnO. On the basis of the XPS data with sputtering depth, we conclude that cationic (1+ and 3+) Au species, plausibly $Au(OH)_x$ (x = 1-3), commonly form mainly at the Au-$TiO_2$ and Au-ZnO interfaces. With $Ar^+$ ion sputtering, the oxidation state of Ti dramatically changes from 4+ to 3+ and 2+ while that (2+) of Zn shows no discernible change based on the binding energy position and the full-width at half maximum (FWHM).

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.12 no.3
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• pp.1168-1188
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• 2018

Social Network Aggregators are used to maintain and manage manifold accounts over multiple online social networks. Displaying the Activity feed for each social network on a common dashboard has been the status quo of social aggregators for long, however retrieving the desired data from various social networks is a major concern. A user inputs the query desiring the specific outcome from the social networks. Since the intention of the query is solely known by user, therefore the output of the query may not be as per user's expectation unless the system considers 'user-centric' factors. Moreover, the quality of solution depends on these user-centric factors, the user inclination and the nature of the network as well. Thus, there is a need for a system that understands the user's intent serving structured objects. Further, choosing the best execution and optimal ranking functions is also a high priority concern. The current work finds motivation from the above requirements and thus proposes the design of a query processing system to retrieve information from social network that extracts user's intent from various social networks. For further improvements in the research the machine learning techniques are incorporated such as Latent Dirichlet Algorithm (LDA) and Ranking Algorithm to improve the query results and fetch the information using data mining techniques.The proposed framework uniquely contributes a user-centric query retrieval model based on natural language and it is worth mentioning that the proposed framework is efficient when compared on temporal metrics. The proposed Query Processing System to Retrieve Information from Social Network (QPSSN) will increase the discoverability of the user, helps the businesses to collaboratively execute promotions, determine new networks and people. It is an innovative approach to investigate the new aspects of social network. The proposed model offers a significant breakthrough scoring up to precision and recall respectively.