• Journal of Life Science
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• v.23 no.5
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• pp.669-675
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• 2013

The stability of monascus pigment produced by Monascus sp. MK2 was investigated according to light, pH, temperature, organic acid, synthetic antioxidant, and natural substance. The light stability was increased (sun light < fluorescent lamp < ultraviolet rays < dark condition) when storing the monascus pigments. Although the monascus pigments were stable in the range of pH 3.0, the degradation rate of pigment was increased at pH 11.0. The stability of monascus pigment gradually decreased as temperature increased. In addition, pigment stability was increased by adding the synthetic antioxidant and natural substance.

• Journal of the Korean Society of Food Science and Nutrition
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• v.23 no.6
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• pp.1001-1007
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• 1994

In order to develop a natural food preservative, dried salviae miltiorrhizae radix (Salvia miltiorrhiza) was extracted with several solvents, and then antimicrobial activity was investigated. The optimum extracting condition for the antimicrobial sustance from the sample, minimal inhibitory concentration (MIC) of the extracted substance against microorganisms were also examined. Antimicrobial activity of the initial ethanol extract from the sample was the strongest compared to those of other solvent extracts such as n-hexane, acetone, butanol, methanol and water. the optimum extractingcondition for antimicrobial substance from the sample was shaking extraction for 2 hours at room temperature incase that 10 volumes of absolute ethanol was added to crushed Saliva Miltiorrhiza. The ethanol extract had strong growth inhibition activity against Gram-positive Bacteria (MIC, 3.13-50$\mu\textrm{g}$/ml) such as B. cereus, B, subtilis, L. minocytogenes, S. aureus, Sc. Mutans. Among Grampositive bacteria tested, Bacillus species was the most susceptibile to the extracted substance. The antimicrobial activity of the ethanol extract from the sample was weak to Gram -negative bacteria yeasts, for example MIC for Gram-negative bacteria and yeasts was 0.8mg/ml and 0.4-0.8mg/ml , respectively.

• Korean Journal of Veterinary Research
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• v.37 no.1
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• pp.9-13
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• 1997

The gastrointestinal endocrine cells of the African clawed toad, Xenopus laevis have been investigated immunohistochemically using the avidin-biotin method. Seven antisera were tested and three endocrine cell types immunoreacted with antisera to neurotensin, GRP and substance P. A moderate number of neurotensin-immunoreactive cells were weakly reacted in the small intestine. GRP-immunoreactive cells were mainly situated among the upper portion in the fundic glands, and the basal portion in the pyloric glands. These cells were oval and round in shape. On the other hand, in the intestine they were thin spindly cells with the epithelium. Substance P-immunoreactive cells were observed in among intestinal epithelium. However, no secretin-, motilin-, M-Enk- and PYY-immunoreactive cells were found in the GIT of the African clawed toads.

• KIEAE Journal
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• v.2 no.1
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• pp.11-19
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• 2002

This Study aims to find out the planning aspects and detailed techniques in terms of concept of the Ecological Industrial Parks. It consists of the three parts : Firstly, according to theoretical review, this study gives a definition of the concept of ecological industrial parks. Secondly, it institutes planning aspects of ecological industrial parks based on the main concept. Thirdly, 8 case studies show us analysis of detailed techniques used each planning aspects. Ecological industrial parks mean industrial systems which make energy and substance circulated in order to reduce environmental pollutions inside and outside of park like natural ecosystem. To actualize ecological industrial parks, we have to adopt 3 planning aspects which are energy and substance recycling system, environmentally-friendly site planning based on ecology concept, constructing of ecological production and management. In case study, detailed techniques from each planning aspects are shown in table 8. As a result of case study, detailed techniques about planning of energy and substance recycling system is accommodated most. On the other hand, environmentally-friendly site planning techniques based on ecological concept is used passively. And detailed techniques about constructing of ecological production and management are very various as each cases. Finally, in terms of analysis, this study shows us appliable planning when we develop domestic Ecological industrial parks.

• Korean Institute of Interior Design Journal
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• no.9
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• pp.38-48
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• 1996

The purpose of this paper is to study the artistic characteristics of light and adjustment in space, and how meaningful this integral phenomenon is to human beings , whin a space is transformed into a dynamic subject by light. When we create a very unique space we need to adjust light in all environments and must recognize the substance of light in all human spaces. The study of interior design is dependant on the existence of these lights in space. Light plays a very integral role in life having great contingency in the artistic characteristics represented in space. Light is a non-materialistic substance. However, when this substance is realized as a materialistic , light has a very visual effect, having a pleasing and satisfying effect on humans. The artistic characteristic of light in interior space are represented through elements of tranquility , direction . recognition, symbolism , and design. Light has a limitless amount of potential for giving humans boundless possibilities in space and expression . By studying psychological and physical aspects of the flow of light we are able to enjoy its fruitful benefits in the space of interior architectural design.

• Food Science and Preservation
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• v.1 no.1
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• pp.1-7
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• 1994

To investigate the effect of several bactericides and fungicides against fruit & vegetable decay grapefruit seed extract(GFSE) was tested in a dilution solution. GFSE was shown to be effective against decay and rind breakdown and to extend the shelf-life of fruits and vegetables during storage and tiansport. Antimicrobial efficiency of GFSE on a wide spectra of gram + & - bacteria, moulds and yeasts was demonstrated by the measurement of minimal inhibitory concentrations performed (Bacteria 10-500ppm, Fungi:250-1,000ppm, Yeasts:100-250ppm). GFSE was separated and extracted into water-soluble fraction, water-insoluble and non-dialyzed fraction to isolate the antimicrobial substances. The water-soluble fraction showed the most active antimicrobial effect. The antimicrobial substances were isolated by gas chromatography. As the result of the isolation using GC, Peak-D was found to be the antimicrobial compound in GFSE. The identification of the most antimicrobial substance was carried out by using GC-MS.

• Journal of Sensor Science and Technology
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• v.32 no.2
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• pp.95-99
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• 2023

Forest healing is an activity that enhances immunity and human health using various elements of nature, such as fragrance and scenery. Particularly, phytoncide composed of terpene, a natural volatile substance emitted by forest plants, activates the immune function and is an important raw material in health-related products, such as antibacterial and insect repellents. Moreover, phytoncide is used as a measure to evaluate the impact of the forest atmosphere on the human body. This study aims to implement a highly sensitive gas sensor system that can measure phytoncide in real-time, which is an essential element for realizing a forest healing environment. A gas generation apparatus was implemented by using an adsorption tube in consideration of filed applicability in a laboratory atmosphere to enable the measurement of α-pinene and limonene, which are among the main components of phytoncide. Throughout the experimental trials, the sensitivity of gas sensor arrays to α-pinene and limonene was confirmed. In addition, the classification results demonstrated the AVOCs and NVOCs can be well discriminated using PCA. The primary results confirmed the possibility of developing a high-sensitivity gas sensor system for phytoncide sensing in real time.

• Food Science and Preservation
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• v.6 no.1
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• pp.66-70
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• 1999

The mechanism of natural removal of astringency and seasonal changes of tannin substance in sweet persimmon(Fuyu) and astrigent persimmon(Chungdo Bansi)were investigated. Tannin productivity of astringent persimmon fruit was higher than that of sweet perimmon fruit during growth. In the reactivity of tannin to acetaldehyde, it was observed that tannin from sweet persimmon have a milder chemical properties than that from astrigent persimmon. The threshold value of astringency on sweet persimmon tannin was higher than that of astrigent persimmon tannin. Tannin substances from sweet persimmon distributed mainly in lower molecular weight range at harvest stage, but those from astrigent persimmon distributed mainly in higher molecular weight range. Therefore, the natural removal of astringency was related to difference of tannin productivity, threshold value of astringency, reactivity and qualitative difference of tanni.

• Journal of the Korean Society for information Management
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• v.39 no.2
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• pp.203-232
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• 2022

Drug addiction or substance use disorder is continuously observed worldwide for its risks and prevalence. In this context, numerous studies have been conducted regarding this issue. However, bibliometric analysis related to drug addiction is insufficient. In particular, it is difficult to find research that utilizes a macro-level bibliographic approach that comprehensively reflects various characteristics related to drug addiction. In this study, to reflect the multidimensional features of drug addiction, research trends in drug addiction in social science, natural science, and multidisciplinary studies were compared and analyzed. This study collected drug addiction research articles from 2002 to 2021 by searching from the Web of Science, and classified academic disciplines based on SCI(E) and SSCI information. Author keyword co-occurrence analysis was also conducted, which provided confirmation that natural science mainly studied psychoactive substances and the reward system in the brain, while drug addiction studies reflecting demographic characteristics were conducted in the domain of social science. In the multidisciplinary field, all of the above topics were covered. Author co-citation analysis was also employed, which showed that there are superstars (i.e., authors who receive a rigorous amount of citation) in the field of natural science, while in the social science domain, authors were highly cited not only at the individual level but also at the institutional level.

• YAKHAK HOEJI
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• v.54 no.4
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• pp.240-243
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• 2010

High-performance liquid chromatography (HPLC) screening method revealed that a propolis product marketed as a functional food contained an undeclared substance similar to tadalafil, the active ingredient of the prescription drug Cialis$^{(R)}$ approved for the treatment of male erectile dysfunction. In order to identify the illegal additive, the propolis product was extracted with methylene chloride, and the extract was purified further using semipreparative HPLC. The chemical structure of the isolated substance was elucidated based on IR, LC/MS-ESI, and $^1H$- and $^{13}C$-NMR spectroscopy, which showed the characteristics similar to tadalafil. The only difference was the substitution of the methyl group at the piperazinedione ring of tadalafil to the amino group of the identified illegal additive.