• 제목/요약/키워드: natural products

검색결과 4,303건 처리시간 0.045초

Constituents from the roots of Sophora flavescens

  • Kim, J.S.;Han, S.J.;Byun, J.H.;Xu, Y.N.;Yoo, S.W.;Kang, S.S.;Son, K.H.;Chang, H.W.;Kim, H.P.
    • 대한약학회:학술대회논문집
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    • 대한약학회 2001년도 Proceedings of the Pharmaceutical Society of Korea
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    • pp.197.1-197.1
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    • 2001
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Effect of Active Synthetic 2-Substituted Quinazolinones on Anti-Platelet Aggregation and the Inhibition of Superoxide Anion Generation by Neutrophils

  • Chang, Fang-Rong;Wu, Chin-Chung;Hwang, Tsong-Long;Patnam, Ramesh;Kuo, Reen-Yen;Wang, Wei-Ya;Lan, Yu-Hsuan;Wu, Yang-Chang
    • Archives of Pharmacal Research
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    • 제26권7호
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    • pp.511-515
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    • 2003
  • Quinazolinones, 2-substituted and 3-substituted, mainly synthesized by microwave irradiation, were subjected to anti-platelet aggregation and inhibition of superoxide anion generation assays. Interestingly, 2-phenyl-4-quinazolinone (4) exhibited significant inhibitory activities toward platelet aggregation and neutrophil activation, and it might therefore serve as a prototype lead compound.

Inhibitors of $5\alpha$-Reductase from the Roots of Angelica koreana

  • Seo, Eun-Kyoung;Kim, Kyeong-Ho;Kim, Min-Ki;Park, Eun-Wook;Kim, Ki-Nam;Lee, Hyun-Tai;Park, Hye-Young;Han, Ah-Reum;Mar, Wong-Chon
    • 대한약학회:학술대회논문집
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    • 대한약학회 2001년도 Proceedings of International Convention of the Pharmaceutical Society of Korea
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    • pp.267.3-268
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    • 2001
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Terpenoids from Artemisia rubripes Nakai

  • Lee, Kyu-Ha;Choi, Sang-Zin;Min, Yong-Deuk;Lee, Sung-Ok;Yang, Min-Cheol;Chung, Ae-Kyung;Nam, Jung-Hwan;Lee, Kang-Ro
    • 대한약학회:학술대회논문집
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    • 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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    • pp.373.1-373.1
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    • 2002
  • Twenty Artemisia species are distributed in South Korea and rich in terpenoids. Artemisia rubripes (Compositae) has been used as a Korean traditional medicine for stomachache. vomiting. diarrhea and hemostatic agent. The antimutagenic effect and essential oils of Artemisia rubripes were reported, but phytochemical study has not been fully investigated. As part of our systematic study on the terpene constituents of Artemisia species. we have investigated A. rubripes (1 kg) collected at Dae-Kwan ryung. Gangwon Province on Aug. 1997. (omitted)

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Phytochemical constituents from Cacalia karaiensis Nakai

  • Lee, Sung-Ok;Choi, Sang-Zin;Kim, Su-Hak;Yang, Min-Cheol;Chung, Ae-Kyung;Nam, Jung-Hwan;Lee, Kyu-Ha;Lee, Kang-Ro
    • 대한약학회:학술대회논문집
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    • 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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    • pp.375.1-375.1
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    • 2002
  • As part of a research program on the bioactive terpene constituents of Korean compositae plants. we have investigated Cacalia koraiensis (compositae). collected from Gangwon Province on August 2001. On reviewing the literatures of this species. triterpenes and pyrrolizidine alkaloids were isolated and some pharmacological activities were investigated. This species have been used for tinea and spasmolysis However. chemical constituents of this plant have not been reported. (omitted)

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Phytochemical Constitutents of Siegesbeckia pubesence Makino.

  • Nam, Jung-Hwan;Choi, Sang-Zin;Lee, Sung-Ok;Yang, Min-Cheol;Chung, Ae-Kyung;Lee, Kyu-Ha;Shin, Dae-Hee;Lee, Kang-Ro
    • 대한약학회:학술대회논문집
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    • 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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    • pp.374.2-374.2
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    • 2002
  • Siegesbeckia pubesence (Cempesitae). a perenial herb, is widely distributed in our country and has been used for rheumaic arthritis, hypertension, malaria. neurasthnia and snake-bite in traditional Chinese medicine. On reviewing the literatures of this plant. diterpenoids and alkaloids were isolated and some pharmacological activities were investigated. As part of our systematic study fer Korean Compositae plants, we have investigated Siegesbeckia pubesence (7kg), cellected from Mt. Odae on Aug. 2001. (omitted)

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Aldose Reductase Inhibitory Constituents from Ganoderma applanatum

  • Shim, Sang-Hee;Ryu, Ji-Young;Kim, Ju-Sun;Kang, Sam-Sik;Chung, Sang-Hun;Lee, Yeon-Sil;Lee, Sang-Hyun;Shin, Kuk-Hyun
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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    • pp.261.1-261.1
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    • 2003
  • The EtOAc and CH$_2$Cl$_2$ soluble fractions from the fruit body of Ganoderma applanatum showed strong aldose reductase inhibitory activity. Nine compounds were isolated from both fractions. They were identified by spectral data as D-mannitol (1), 2-methoxyfatty acid (2), cerebrosides [(2S,3R,4E,8E)-1-O-${\beta}$-D-glucopyranosyl-3-hydroxy-2-[(R)-2'-hydroxypalmitoyl]amino-9-methyl-4,8-octadecadiene] (3), daucosterol (4), 2,5-dihydroxybenzoic acid (5), protocatechualdehyde (6), 5-dihydroergosterol (7), ergosterol peroxide (8), and cerevisterol (9). (omitted)

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Phytochemical Constituents from Saussurea nutans

  • Choi, Sang-Zin;Lee, Sung-Ok;Yang, Min-Cheol;Nam, Jung-Hwan;Lee, Kyu-Ha;Jang, Ki-Uk;Lee, Jong-Hwa;Lee, Kang-Ro
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2-2
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    • pp.198.1-198.1
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    • 2003
  • As part of our systematic study for Korean Compositae plants, we have studied Saussurea nutans, collected at Gangwon Province on August 2001. Phytochemical studies on various species of genus Saussurea have resulted in the isolation sesquiterpene, triterpene and flavonoid$\^$1)/. S. nutans has been used for the treatment of rheumatic arthritis and dysmenorrhea in the Chinese folk medicine$\^$2)/. However, chemical constituents of this plant have not been reported until now. The MeOH extract of the aerial parts of this source was solvent fractionated into n-hexane, methylene chloride, ethyl acetate and BuOH soluble portions. (omitted)

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