• YAKHAK HOEJI
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• v.17 no.3
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• pp.129-136
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• 1973

In order to establish the chemical standards for the quality control of ginsentgextract, an approach for the assay of sapogenin contents in the part of main roots and fibrous side roots was performed by combination of preparative thin layer chromotographic procedure and vanillin-$H_{2}SO_{4}$ color reaction. The contents of dammarane aglycones as funcction of dammarane glycosides in 80%-EtOH extracts were analyzed by the method from the main roots and fibrous side roots of Korean ginseng grown for 4-6 years. The differences by their grown ages in the contents of dammarane glycosides, in the ratio of panaxadiol to panaxatriol contents, and in the mounts of 80% EtOH extract were not significant in the parts of main roots and fibrous side roots of Korean gingeng. Differences due to the part for medicinal uses were highly significant in all parameters mentioned, showing following results ; in the main roots ; 80% EtOH extract, 12.7-15.7 % : the ratio of aglycone composition, 0.955-1.012 : dammarane glycoside (as diglucoside bases), 1.537-1.863 ; in fibrous isde roots ; 80% EtOH extract, 26.0-26.02% : dammarane glycoside, 4.767-5.641 : the ratio, 1.456-1.50.

• Bulletin of the Korean Chemical Society
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• v.28 no.8
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• pp.1363-1370
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• 2007

The geometrical structures of pyridazin-3-one derivatives (4,5-dihalopyridazin-3-one and 4-halo-5- alkoxypyridazin-3-one) with various functional and substituent groups were fully optimized using the ab initio Hartree-Fock (HF) and second order Moller-Plesset perturbation (MP2) methods. At the N2-, C4-, and C5- positions on the pyridazin-3-one rings, the structural and electronic features pertaining to the variations of the functional and substituent groups were analyzed, respectively. The trends in the variation of the bond lengths, atomic charges, and energetics (relative energy, binding energy) of the derivatives induced by changing the electron donating functional groups (X1 = OMe, OEt) to electron withdrawing groups (X1 = Cl, NO2) were examined. The variations of the bond lengths, atomic charges, and binding energies with the electron withdrawing strength of the substituent groups (Y = Me → F) were also investigated.

• Mycobiology
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• v.28 no.1
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• pp.11-16
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• 2000

The nucleotide sequences of the internal transcribed spacer (ITS) regions of the ribosomal DNA including the 5.8S ribosomal RNA gene (rDNA) have been determined for 11 species in order to analyze their intrageneric relationships. The total length of these sequences ranged from 530 nucleotides for Trichoderma reesei KCTC 1286 to 553 nucleotide for Trichoderma koningii IAM 12534. Generally speaking, the length of ITS1 region was about 30 nucleotides longer than that of the ITS2 region. Also, the sequences of 5.8S rDNA were more conserved in length and variation than those of ITS regions. Although the variable ITS sequences were often ambiguously aligned, the conserved sites were also found. Thus, a neighbor-joining tree was constructed using the full sequence data of the ITS regions and the 5.8S rDNA. The Trichoderma genus used to be grouped on the basis of the morphological features and especially the shape of phialides needs to be reexamined. The phylogenetic tree displayed the presence of monophylogeny in the species of Trichoderma. Therefore, it was difficult to distinguish the intrageneric relationships in the Trichoderma genus.

• Nuclear Engineering and Technology
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• v.6 no.1
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• pp.3-8
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• 1974

The annealing of natural beryl powder used for the thermoluminescent dosimetry was investigated in order to eliminate effect of previous exposure. Through the glow curve analysis, the optimal annealing treatment was found to be one hour annealing at 145$0^{\circ}C$, but annealing for one hour at 55$0^{\circ}C$ was sufficient for reuse of natural beryl powder. There are two distinguished glow peaks at $65^{\circ}C$ and 20$0^{\circ}C$ of heating temperature during readout process. The $65^{\circ}C$ glow peak fades away rapidly, but the 20$0^{\circ}C$ glow peak remains very stable. It is, therefore, quite feasible to use the 20$0^{\circ}C$ glow peak for thermoluminescent dosimetry.

• The Korean Journal of Zoology
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• v.29 no.4
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• pp.235-244
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• 1986

In order to elucidate the effect of neurotransmitter on the differention of myoblasts in vitro, dopamine was administered to the myoblasts at varying stages of myogenesis, and the fusion index, the rate of creatine kinase (CK) synthesis, and the sensitivity to dopamine were determined. When dopamine $(3 \\times 10^{-5} M)$ was administered at 34 hr after myoblast seeding, a significant decrease in the fusion index as well as CK synthesis was observed, indicating a good correlation exists between these two parameters. In other experiment, dopamine was administered at varying stages of myogenesis and the inhibitory effect of dopamine as scored by fusion index at 96 hr was found to be cyclic in nature. This finding raised a possibility that arrangement of dopamine receptors occurs according to the cell cycle stages in myogenesis.

• Animal cells and systems
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• v.7 no.3
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• pp.207-211
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• 2003

Caveolin-1 is a principal protein in the plasma membrane microdomains called caveolae. Caveolae play an important role in the transcytosis and pinocytosis. Therefore, caveolin-1 is most likely to work for the membrane dynamic events. In addition, caveolin-1 interacts with various signaling molecules. Although caveolin-1 possesses a variety of physiological functions, its structural properties were little construed. Here we analyzed the structural dynamics of the N-terminal caveolin-1 (residues 1-101), in order to better understand the structural properties in terms of its versatile functionality. We first analyzed its oligomeric form using GST-fused N-terminal domain, revealing that it equilibrates between a dimer and monomers in av concentration-dependent manner. The N-terminal domain of caveolin-1 was previously found to form a heptamer, so that our data suggest the dimeric form as an intermediate structure for the heptamer formation. Then, we obtained the folding profile, which indicated that $\DeltaG_{H2O}\;is\;about\;0.5\;\pm0.03$ kcal/mol. The stability of N-terminal domain is relatively low, indicating that N-terminal domain may not be crystalline. Conclusively, the dynamic and flexible structure of N-terminal domain appears more favorable to maintain the versatile functions of caveolin-1.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2003.05a
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• pp.1073-1078
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• 2003

This paper presents the vibration characteristics of a cantilever beam in contact with a fluid using a PZT actuator and PVDF film. dynamic behaviors of a flexible beam-water interaction system are examined. The effect of the liquid level on free vibration of the composite beam in a partially liquid-filled circular cylinder is investigated. The coupled system is subject to an undisturbed boundary condition un the fluid domain. In the vibration analysis of a wetted beam. the decoupled analyses between beam and fluid have been conventionally employed by considering first the composite beam vibration in the all and secondly Performing the correction taking account for surrounding fluid effects. That is, this investigation was to look at how natural frequencies, mode shapes. and damping are affected by liquid level variations. The signals from the sensor according to the applied input voltage are digitalized and filtered in order to obtain the dynamic characteristics of the composite beam in contact with fluid. It was found that the coupled natural frequencies decreased with the fluid level for the identical composite beam due to added mass effect. In case of the free-free boundary condition, the natural frequency gently decreased at fluid water level between 20% and 80% in the first tending mode and we found out the bends of stair shape for added mass effect of the fluid.

• Journal of the Korea Safety Management & Science
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• v.10 no.4
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• pp.275-286
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• 2008

The purpose of this study verifies: the relationship between self-leadership (behavioral-focused strategies, natural reward strategies, constructive thought pattern strategies) and innovative behavior, and mediator effect of trust in supervisor. In order to verify the relationship and mediator effect, data obtained from 140 employees working in business office in Ulsan Metropolitan City were analyzed by using SPSS 12.0. The findings are as follows: First, the relationship between self-leadership(behavioral- focused strategies, natural reward strategies, constructive thought pattern strategies) and trust in supervisor is positively related Second, There was also a positive correlation between the trust in supervisor and innovative behavior. Finally, trust in supervisor played as a partial mediator on the relationship between self-leadership(behavioral- focused strategies, natural reward strategies, constructive thought pattern strategies) and innovative behavior. Based on these findings, the implications and the limitations of the study were presented including some directions for future studies.

• Archives of Pharmacal Research
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• v.27 no.6
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• pp.619-623
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• 2004

Tissue factor (TF, tissue thromboplastin) is a membrane bound glycoprotein, which acceler-ates the blood clotting, activating both the intrinsic and the extrinsic pathways to serve as a cofactor for activated factor VII (Vila). The TF-factor Vila complex (TF/VIIa) proteolytically activates factors IX and X, which leads to the generation of thrombin and fibrin clots. In order to isolate TF inhibitors, by means of a bioassay-directed chromatographic separation technique, from the leaves of Eriobotrya japonica Lindley (Rosaceae), a known sesquiterpene glycoside (2) and ferulic acid (3) were isolated as inhibitors that were evaluated using a single-clotting assay method for determining TF activity. Another sesquiterpene glycoside (1) was also isolated but was inactive in the assay system. Compound 3 was yielded by alkaline hydrolysis of compound 2. The structures of compounds 1, 2, and 3 were identified by means of spectral analysis as $3-O-{\alph}-L-rhamnopyranosyl-(1{\rightarrow}4)-a-L-rhamnopyranosyl-(1{\rightarrow}2)-[{\alph}-L-rhamnopyrano-syl-(1{\rightarrow}6)]-{\beta}-D-glucopyranosyl nerolidol$ (1), $3-O-{\alph}-L-rhamnopyranosyl-(1{\rightarrow}4)-{\alph}-L-rhamnopyr-anosyl-(1{\rightarrow}2)-[{\alph}-L-(4-trans-feruloyl)-rhamnopyranosyl-(1{\rightarrow}6)]-{\beta}-D-glucopyranosyl$ nerolidol (2) and ferulic acid (3), respectively. Compounds 2 and 3 inhibited 50% of the TF activity at con-centrations of 2 and $369{\;}\mu\textrm{m}/TF$ units, respectively.

• Proceedings of the IEEK Conference
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• summer
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• pp.103-109
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• 2004

In NLP (Natural Language Processing) tasks, the highest difficulty which computers had to face with, is the built-in ambiguity of Natural Languages. To disambiguate it, formerly, they based on human-devised rules. Building such a complete rule-set is time-consuming and labor-intensive task whilst it doesn't cover all the cases. Besides, when the scale of system increases, it is very difficult to control that rule-set. So, recently, many NLP tasks have changed from rule-based approaches into corpus-based approaches with large annotated corpora. Corpus-based NLP tasks for such popular languages as English, French, etc. have been well studied with satisfactory achievements. In contrast, corpus-based NLP tasks for Vietnamese are at a deadlock due to absence of annotated training data. Furthermore, hand-annotation of even reasonably well-determined features such as part-of-speech (POS) tags has proved to be labor intensive and costly. In this paper, we present our building an annotated English-Vietnamese parallel aligned corpus named EVC to train for Vietnamese-related NLP tasks such as Word Segmentation, POS-tagger, Word Order transfer, Word Sense Disambiguation, English-to-Vietnamese Machine Translation, etc.