• Korean Journal of Medicinal Crop Science
• /
• v.15 no.6
• /
• pp.417-428
• /
• 2007

Most oriental medicinal plants in domestic markets have been imported, but these medicines are being easily exposed to many insect pests because of the poorness of storage facilities. This study was carried out to identify stored products insect pests occurring in 158 storage medicinal plants belonging to 134 genera of 67 families. No insect pests were not observed in 44 medicinal plants including Artemisia argyi Levl. et Vant., Cassia sieboldii Presl., and Juniperus chinensis L. Most commonly observed stored products insect pests in the surveyed medicinal plants were the order of as follows; Ahasverus advena(Waltl) 12.3%, Lasioderma serricorne F. 11.5%, Oryzaephilus surinamensis L. 10.3%, Tribolium castaneum (Herbst) 9.4%, Stegobium paniceum L. 8.4%, and Plodia interpunctella(Hbner) 7.9%. And these insects also are likely to prefer more root or rhizome part than the other ones. Based on these basic survey results, natural products researchers can obtain an important information in finding an insecticidal or fumigant compounds contained in the medicinal plants which any insect pests do not attack.

• Food Science and Preservation
• /
• v.6 no.1
• /
• pp.110-114
• /
• 1999

In order to study the natural preservation of food, sixteen kinds of medicinal plants were extracted by 80% methanol and then antimicrobial activity of the extracts was investigated against various kinds of microorganisms. The extracts of medicinal plants showed good effects of antimicrobial activity against bacteria except Bacillus cereus, Escherichia coli O-157. Especially, the extracts of Artemisia annua, Aster scaber, Solidago virganrea shower good inhibitory effects on the growth of bacteria to the cooling preservation foods, and Artemisia annua was decreased of the TMA(Trimethylamine) test. the result thus indicate that Artemisia annua, Aster scaber, Solidago fischeri extract inhibitory effects on cooling preservation foods, so that it may be potential as a natural preservatives.

• Journal of Microbiology and Biotechnology
• /
• v.27 no.7
• /
• pp.1242-1248
• /
• 2017

Several medicinal plants are ethnomedically used in Korea as agents for treating infection, anti-inflammation, and pain relief. However, beyond typical inhibitory effects on cell growth, little is known about the potential anti-biofilm activity of these herbs, which may help to prevent cavities and maintain good oral health. This study aimed to investigate the antimicrobial and anti-biofilm activities of the methanol extracts of 37 Korean medicinal plants against dental pathogens Streptococcus mutans and Candida albicans, which synergize their virulence so as to induce the formation of plaque biofilms in the oral cavity. The antimicrobial activities were investigated by broth dilution and disk diffusion assay. The anti-biofilm and antioxidant activities were evaluated based on the inhibitory effect against glucosyltransferase (GTase) and the DPPH assay, respectively. Among 37 herbs, eight plant extracts presented growth and biofilm inhibitory activities against both etiologic bacteria. Among them, the methanol extracts (1.0 mg/ml) from Camellia japonica and Thuja orientalis significantly inhibited the growth of both bacteria by over 76% and over 83% in liquid media, respectively. Minimum inhibitory concentration (MIC) values of these methanol extracts were determined to be 0.5 mg/ml using a disk diffusion assay on solid agar media. Biofilm formation was inhibited by more than 92.4% and 98.0%, respectively, using the same concentration of each extract. The present results demonstrate that the medicinal plants C. japonica and T. orientalis are potentially useful as antimicrobial and anti-biofilm agents in preventing dental diseases.

• Korean Journal of Pharmacognosy
• /
• v.8 no.3
• /
• pp.125-129
• /
• 1977

Literature survey was undertaken to investigate what medicinal plants have been used as hepatotonic or for treatment of various liver diseases in far eastern asian countries. Total 59 plants were found to be described in the literatures. And 9 plants among them were studied on their hepatotonic activities against animal model of hepatitis. Several plants appeared to exhibit profound activities on the hepatitis model employed.

• Korean Journal of Pharmacognosy
• /
• v.10 no.2
• /
• pp.79-82
• /
• 1979

Total fourty-four medicinal plants described in old literatures to be hepatotonic were evaluated their potential hepatotonic activities against an animal model of hepatitis. Tweenty-seven plants extracts appeared to be significant hepatotonic activities, whereas twelve plants extracts exhibited rather some toxicity. And five plants extracts showed no significant hapatotonic activities and toxicity.

• Journal of Pharmacopuncture
• /
• v.22 no.3
• /
• pp.131-139
• /
• 2019

Introduction: Mastalgia is the most common benign breast disorder during the fertility period of women. So far a wide range of natural or complementary medicines is used to cure mastalgia. Sanitary organizations need complete and suitable details to help women, for making the proper decision for alternative treatment based on the evidence. The aim of the present study is to introduce medicinal plant-based treatments about mastalgia and summarizes clinical trials about this disorder. Method: The articles were provided using mixture of keywords including cyclic pain, breast, treatment, therapeutics, therapy, clinical trial, herbal, drug, mastalgia and all the probable terms, in national and international databases SID, Iran Medex, Magiran, PubMed, Scopus, Medline, Science direct and Cochrane library, in both Persian and English languages. All cross-sectional and review articles about herbal treatment of mastalgia until 2018 November were studied. Results: Nineteen articles from all of the available articles (45 cases) and a sample size about of (1987 cases) were included in our study. The articles were clinical trials. The results revealed that mastalgia could be healed by Nigella sativa, Vitex agnus-castus, curcumin, Hypericum perforatum, Citrus sinensis, wheat germ, and Ginkgo biloba. Conclusion: Most of the evaluated medicinal plants possessing antioxidant compounds with anti-inflammatory and analgesic properties, exhibited healing effects in the treatment of mastalgia. Thus, medicinal plants can be considered in the treatment of mastalgia; however, further investigations are needed to obtain more details about their probable side effects.

• Korean Journal of Pharmacognosy
• /
• v.1 no.4
• /
• pp.133-142
• /
• 1970

The author has investigated the plant flora of Baek-Ah Island during the period from August 4 to August 10 1970, and found that the flora consist of the plants of coastal, temperature and warm zones. The present report lists 81 families, 190 genera and 235 species of plants, of which 73 families and 170 species are medicinal plants.

• Natural Product Sciences
• /
• v.27 no.4
• /
• pp.217-227
• /
• 2021

This study is a record of ethnomedicinal knowledge in Begumganj province focussed on medicinal plants and their local uses for primary health care. The aim was to document and preserve the ethnomedicinal knowledge used by traditional healers of Begumganj upazila, Bangladesh, to treat human diseases and evaluate the relative efficacy of the medicinal plants. The uses of medicinal plants were documented as an ethnomedicinal data sheet using direct observation, field interview, plant interview and group interview techniques from December 2012 to January 2014 in the study area. Data were collected from 98 traditional healers through a questionnaire survey and analyzed through informant consensus factor and fidelity level. This study revealed comprehensive relationship among various diseases and families, forms and parts of plants and modes of preparation. Overall, 75 plant species under 71 genera of 47 families were documented, which are used to treat 41 diseases. Data analysis revealed that 41.33%, 14.67%, 36% and 8% of the medicinal plant species were herbs, shrubs, trees, and climbers, respectively. Leaves were the most used parts, followed by stem, root, fruit, bark, latex and rhizome. The most frequently treated diseases were dysentery, rheumatism and skin diseases. This is the first ethnobotanical survey, which recorded the importance of medicinal plants in Begumganj upazila, Bangladesh. This study can contribute to preserving the indigenous knowledge on the traditional use of medicinal plants in this region and new drug development with attracting future generations towards traditional healing practice.

• Korean Journal of Pharmacognosy
• /
• v.30 no.2
• /
• pp.211-215
• /
• 1999

This study was aimed to evaluate an agonistic activity to benzodiazepine receptor of several medicinal plants, which have been used as sedatives in oriental medicine. Methanol extracts of medicinal plants which were used in this study inhibited the binding of $[^3H]Ro15-1788$, a selective benzodiazepine receptor antagonist to benzodiazepine receptor of rat cortices. Inhibitory activity of Cyperus rotundus was observed to be the highest among the tested medicinal plants. Methanol extracts of Cyperus rotundus and Zizypus jujuba inhibited a $[^3H]flunitrazepam$, a selective benzodiazepine receptor agonist, binding to benzodiazepine receptor. GABA significantly enhanced the inhibition of $[3H]flunitrazepam$ binding by Cyperus rotundus and Zizypus jujuba, and these positive GABA shifts supported the strong possibility of agonistic activity to benzodiazepine receptor. From these results, it may be concluded that the substance or substances with neurochemical properties characteristic of a benzodiazepine receptor agonist may be important components and contribute to the sedative property of these medicinal plants.

• Natural Product Sciences
• /
• v.11 no.4
• /
• pp.233-239
• /
• 2005

The aerial parts of Gomphocarpus sinaicus Boiss. yielded four flavonoids that were identified as isorhamnetin 3-O-rhamnoglucoside (1), luteolin-7-O-glucoside-3-O-rhamnoside (2), rutin (3) and rutin-7-O-rhamnoside (4). All of the isolated flavonoids were identified by spectroscopic methods (UV, FAB-MS, $^1H-NMR\;&\;^{13}C-NMR$) and in comparison with the literature data. The isolated flavonoids 1, 2 and 4 are reported here for the first time from Gomphocarpus sinaicus Boiss. Three sets of experiments were carried out using the defatted alcoholic extract of Gomphocarpus sinaicus Boiss: the $1^{st}$ experiment indicated that the $LD_{50}$ was 49.82 mg/100 g b.wt. of intraperitoneally (i.p.) injected mice. The toxic signs were recorded within the first 24 hr post-injection. The $2^{nd}$ experiment revealed that the extract of the plant exhibited significant anti-inflammatory effects in normal rats. The $3^{rd}$ experiment was found that the tested doses of the extract in diabetic rats induced a significant decrease in serum glucose, AST, ALT, triglycerides, cholesterol and LDL, while HDL caused a significant increase.