• Proceedings of the Korean Geotechical Society Conference
• /
• 2000.11a
• /
• pp.745-750
• /
• 2000

The shear strength of rock discontinuities is very important in many rock engineering project including analysis of tunnel and slope. But shear strength of rock that acquired through discontinuity shear test is different from soil shear test and more complex. Shear strength is effected by the factors which are various, but it is the best influence of filling material and joint roughness. In this research, we studied shear strength characters of natural joint of phillite that was placed importance on joint roughness, JRC is less low than 8.

• Journal of Ginseng Research
• /
• v.47 no.4
• /
• pp.543-551
• /
• 2023

Background: Panax ginseng Meyer is a representative Chinese herbal medicine with antioxidant and anti-inflammatory activity. 20(S)-Protopanaxadiol (PPD) has been isolated from ginseng and shown to have promising pharmacological activities. However, effects of PDD on pulmonary fibrosis (PF) have not been reported. We hypothesize that PDD may reverse inflammation-induced PF and be a novel therapeutic strategy. Methods: Adult male C57BL/6 mice were used to establish a model of PF induced by bleomycin (BLM). The pulmonary index was measured, and histological and immunohistochemical examinations were made. Cell cultures of mouse alveolar epithelial cells were analyzed with Western blotting, coimmunoprecipitation, immunofluorescence, immunohistochemistry, siRNA transfection, cellular thermal shift assay and qRT-PCR. Results: The survival rate of PPD-treated mice was higher than that of untreated BLM-challenged mice. Expression of fibrotic hallmarks, including α-SMA, TGF-β1 and collagen I, was reduced by PPD treatment, indicating attenuation of PF. Mice exposed to BLM had higher STING levels in lung tissue, and this was reduced by phosphorylated AMPK after activation by PPD. The role of phosphorylated AMPK in suppressing STING was confirmed in TGF-b1-incubated cells. Both in vivo and in vitro analyses indicated that PPD treatment attenuated BLM-induced PF by modulating the AMPK/STING signaling pathway. Conclusion: PPD ameliorated BLM-induced PF by multi-target regulation. The current study may help develop new therapeutic strategies for preventing PF.

• Korean Journal of Applied Biomechanics
• /
• v.22 no.3
• /
• pp.305-314
• /
• 2012

The purpose of this study was to investigate the effects of joint kinetics and coordination on within-individual differences in maximum vertical jump. 10 male subjects aged 20 to 30 performed six trials in maximum vertical jump and with based on jump height the good(GP) and bad(BP) performances for each subject were compared on joint kinetics of lower extremity and coordination parameters such as joint reverse and relative phase. The results showed that maximum moment, power, and work done of hip joint and maximum moment of ankle joint in GP were significantly higher than that in the BP but no significant differences for the knee joint. We could observe a significant difference in joint reverse timing between both conditions. And also the relative phase on ankle-knee and ankle-hip in GP were significantly lower than that in the BP, which means that in GP joint movements were more in-phase synchronized mode. In conclusion, mechanical outputs of hip and ankle joints had an effect on within-individual differences in vertical jump and the inter-joint coordination and coordination including sequence and timing of joint motion also might be high influential factors on the performances within individual.

• Journal of the Korean Society of Manufacturing Technology Engineers
• /
• v.20 no.4
• /
• pp.427-433
• /
• 2011

Chassis part in automotive body is affected by fatigue load at driving on the ground. Universal joint on this part is influenced extremely by the fatigue load. Fatigue life, damage and natural frequency are analyzed at universal joint under nonuniform fatigue load. The york part at universal joint is shown with the maximum equivalent stress and displacement of 60.755 MPa and 0.21086 mm as strength analysis. The possible life in use in case of 'SAE bracket' is the shortest among the fatigue loading lives of 'SAE bracket', 'SAE transmission' and 'Sine Wave'. The damage at loading life of 'SAE transmission' is the least among 3 types. The frequency of damage in case of 'Sine Wave' is 0.7 with the least among 3 fatigue loading life types but this case brings the most possible damage as 80% at the average stress of 0. Natural vibration at this model is analyzed with the orders of 1'st to 5'th and maximum frequency is shown as 701.73 Hz at 5'th order. As the result of this study is applied by the universal joint on chassis part, the prevention on fatigue damage in automotive body and its durability are predicted.

• Journal of Welding and Joining
• /
• v.23 no.6
• /
• pp.67-71
• /
• 2005

This paper is concerned with a study on fracture strength of composites in an adhesive single lap joint. The tests were carried out on joint specimens made with hybrid stacked composites consisting of the polyester and bamboo natural fiber layer. The main objective of this work was to evaluate the fracture properties adjacent to adhesive bonded joint of natural fiber reinforced composite specimens. From the results, natural fiber reinforced composites have lower tensile strength than the original polyester. But tensile-shear strength of natural fiber reinforced composites with bamboo layer far from adhesive bond is as high as that of the original polyester adhesive bonded joints. Spew filet at the end of the overlap reduced the stress concentration at the bonded area. Spew fillet and position of bamboo natural fiber layer have a peat effect on the tensile-shear strength of natural fiber reinforced composites including adhesive bonded joints.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
• /
• v.5 no.4
• /
• pp.265-277
• /
• 1993

Recently, underground transmission system is growing continuously according to the electric power demand increase in the downtown area. Even if domestic cable makers are manufacturing 154kV oil filled cable and joint, the design technology of cable-joint has not been fully self-reliance. This study is aimed at the detail heat transfer analysis of 154kV cable-joint. So, that is cut into the five sections in order to analyze a conjugate natural convection in two dimensional $r-{\theta}$ coordinate. The streamline and temperature distributions are obtained for each sections. Also the changes of those are analyzed with respect to the variation of transmission currents and cable-joint surface heat transfer coefficients. The same analyses are also shown in view point of the maximum temperature of conductor and local equivalent conductivity.

• Journal of the Korean Society of Manufacturing Process Engineers
• /
• v.7 no.3
• /
• pp.36-40
• /
• 2008

This study is analyzed by the simulation of automotive steering system. The maximum equivalent stress of $2.2418{\times}109Pa$ and the maximum total displacement of 0.014929m are shown at the universal joint and its lower part respectively. As the minimum cycle of 34.047 is shown at the universal joint in case of fatigue analysis, it is possible to have greatest damage at this part. In case of natural frequency analysis at vibration, its frequency of 47 to 59Hz is occurred generally. The maximum total displacement of 0.5m is shown at handle on the natural frequency of 57 to 58Hz. And the displacement over 2m is shown at the lower part of universal joint on the natural frequency of 58 to 59Hz. As the basis of the simulation analysis of steering system, passenger's comfort of car body can be improved in the design of practical part and the design effect necessary to safe driving can be promoted.

• Macromolecular Research
• /
• v.15 no.1
• /
• pp.65-73
• /
• 2007

Chitosan, fibroin, and hydroxyapatite are natural biopolymers and bioceramics that are biocompatible, biodegradable, and resorb able for biomedical applications. The highly porous, chitosan-based, bioceramic hybrid composite, chitosanlfibroin-hydroxyapatite composite, was prepared by a novel method using thermally induced phase separation. The composite had a porosity of more than 94% and exhibited two continuous and different morphologies: an irregularly isotropic pore structure on the surface and a regularly anisotropic multilayered structure in the interior. In addition, the composite was composed of an interconnected open pore structure with a pore size below a few hundred microns. The chemical composition, pore morphology, microstructure, fluid absorptivity, protein permeability, and mechanical strength were investigated according to the composition rate of bioceramics to biopolymers for use in tissue engineering. The incorporation of hydroxyapatite improved the fluid absorptivity, protein permeability, and tenacity of the composite while maintaining high porosity and a suitable microstructure.

• Geomechanics and Engineering
• /
• v.29 no.3
• /
• pp.207-218
• /
• 2022

In submerged floating tunnels (SFTs), a next-generation maritime transportation infrastructure, the tunnel module floats in water due to buoyancy. For the effective and economical use of SFTs, connection with the ground is inevitable, but the stability of the shore connection is weak due to stress concentration caused by the displacement difference between the subsea bored tunnel and the SFT. The use of an elastic joint has been proposed as a solution to solve the stability problem, but it changes the dynamic characteristics of the SFT, such as natural frequency and mode shape. In this study, the finite element method (FEM) was used to simulate the elastic joints in shore connections, assuming that the ground is a hard rock without displacement. In addition, a small-scale model test was performed for FEM model validation. A parametric study was conducted on the resonance behavior such as the natural frequency change and velocity, stress, and reaction force distribution change of the SFT system by varying the joint stiffness under loading conditions of various frequencies and directions. The results indicated that the natural frequency of the SFT system increased as the stiffness of the elastic joint increased, and the risk of resonance was the highest in the low-frequency environment. Moreover, stress concentration was observed in both the SFT and the shore connection when resonance occurred in the vertical mode. The results of this study are expected to be utilized in the process of quantitative research such as designing elastic joints to prevent resonance in the future.

• Journal of the Korean Society of Manufacturing Technology Engineers
• /
• v.8 no.2
• /
• pp.73-79
• /
• 1999

Most of mechanical structures are combined of substructures such as beams and/or plates. There are few systems with unibody structures but are many systems with united body structures. Generally the dynamic a nalysis of whole structures is performed under alternation load. In the structure design, the analysis of each bolted joint is more important than others for zero severity. This paper presents the analysis method of contact stress distribution factor in the bolted joint with variable fastening torque on joints in the structure. At first, a static vibration test was performed to find out a nominal stress of bolt jointed plates from the relationship between natural frequency and nominal stress. Then a contact stress was computed at contact point between bolt and plate in the structure. It is believed that the proposed method has promisiong implications for safer design with index of contact stress distribution factor and has merits for cost-down and saving time at the beginning of vehicle development.