• Title/Summary/Keyword: native region

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Energy Loading in the Metastable Native Structure of Inhibitory Serpins

  • Hana Im;Seo, Eun-Joo;Yu, Myeong-Hee
    • Proceedings of the Korean Biophysical Society Conference
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    • 1998.06a
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    • pp.23-23
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    • 1998
  • To understand structural and functional basis of loaded energy in the metastable native structure of inhibitory serpins (serine protease inhibitors), we characterized mutations that decreased the loaded energy of ${\alpha}$$_1$-antitrypsin and simultaneously influenced its inhibitory activity. Various folding defects such as side-chain locking, buried polar groups in unfavorable hydrophobic environment, and cavities were found as the structural basis of the metastability of ${\alpha}$$_1$-antitrypsin in a region presumably directly involved in the formation of complex between the inhibitor and a target protease.(omitted)

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Radiographic Diagnosis of Hypospadias in Three Korean Native Calves

  • Jeong, Won-Seok;Seong, Yun-Sang;Kim, In-Su;Jang, Hwan-Soo;Oh, Tae-Ho;Lee, Keun-Woo;Jang, Kwang-Ho
    • Journal of Veterinary Clinics
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    • v.25 no.6
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    • pp.557-559
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    • 2008
  • Three calves which were born in a village with similar symptoms that urine ran down along the inner femoral region were referred to Veterinary Medical Teaching Hospital, Kyungpook National University. On physical examination, there were aplasia of the penis, ventrally incomplete sheath and bifid scrotum in common. Blood cell count test and blood biochemistry test were performed and then diagnostic radiography was carried out in a case. Retrograde positive cystograph showed normal urinary bladder and no other urogenital abnormalities. The shape and size of the testes were normal on ultrasonographs, yet intact urethral wall was not detected. These cases were diagnosed as hypospadias.

Studies on red cell fragility and glutathione peroxidase activities in Korean native cattle of Chonbuk region (전북지역 한우의 red cell fragility와 glutathione peroxidase활성에 관한 연구)

  • Cho, Jong-hoo;Lee, Seong-hee
    • Korean Journal of Veterinary Research
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    • v.30 no.3
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    • pp.271-275
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    • 1990
  • The tests related to red cell fragility were performed. Samples of blood anticoagulated with heparin were obtained from Korean native cattle in Chonbuk region abattoir, and classified by the district(Kun) with reference to breeding location. Hemolysis test for red cell fragility was performed with whole blood and glutathione peroxidase activity was measured spectrophotometrically. Blood concentration of selenium, inorganic component of glutathione peroxidase, was also determined fluorophotometrically. The results obtained were summerized as follows; 1. Percent hemolysis of erythrocytes ranged from 13.53 to 20.74%, and its mean Palue was low as $17.11{\pm}9.91%$. Means in all were not district(Kun) in Chonbuk region significantly different. 2. Glutathione peroxidase activity ranged from 2,881 to 4,000mU/ml, and high mean values, $3,352{\pm}1,872mU/ml$, reflected low percent hemolysis. 3. There was a highly negative correlation between the red cell fragility(Y) and blood glutathione peroxidase activity(X). The linear regression equation for these data was: Y=29.86-3.75X with a correlation coefficient of r=-.6886 (p<0.01) 4. Blood selenium concentration ranged from 0.16 to $0.24{\mu}g/ml$, and mean values was normal level as $0.2{\pm}0.11{\mu}g/ml$. 5. There was a highly positive correlation between blood selenium concentration(X), and blood glutathione peroxidase activity(Y). The linear regression for these data was: Y=230+15,790X, with a correlation coefficient officient of r=0. 8635.

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Association of the Single Nucleotide Polymorphisms in RUNX1, DYRK1A, and KCNJ15 with Blood Related Traits in Pigs

  • Lee, Jae-Bong;Yoo, Chae-Kyoung;Park, Hee-Bok;Cho, In-Cheol;Lim, Hyun-Tae
    • Asian-Australasian Journal of Animal Sciences
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    • v.29 no.12
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    • pp.1675-1681
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    • 2016
  • The aim of this study was to detect positional candidate genes located within the support interval (SI) regions based on the results of red blood cell, mean corpuscular volume (MCV), and mean corpuscular hemoglobin quantitative trait locus (QTL) in Sus scrofa chromosome 13, and to verify the correlation between specific single-nucleotide polymorphisms (SNPs) located in the exonic region of the positional candidate gene and the three genetic traits. The flanking markers of the three QTL SI regions are SW38 and S0215. Within the QTL SI regions, 44 genes were located, and runt-related transcription factor 1, dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A), and potassium inwardly-rectifying channel, subfamily J, member 15 KCNJ15-which are reported to be related to the hematological traits and clinical features of Down syndrome-were selected as positional candidate genes. The ten SNPs located in the exonic region of the three genes were detected by next generation sequencing. A total of 1,232 pigs of an $F_2$ resource population between Landrace and Korean native pigs were genotyped. To investigate the effects of the three genes on each genotype, a mixed-effect model which is the considering family structure model was used to evaluate the associations between the SNPs and three genetic traits in the $F_2$ intercross population. Among them, the MCV level was highly significant (nominal $p=9.8{\times}10^{-9}$) in association with the DYRK1A-SNP1 (c.2989 G$F_2$ intercross, our approach has limited power to distinguish one particular positional candidate gene from a QTL region.

Studies on the Origin of Punk Hair Style -With Specific Emphases on Cockcomb Hair Style- (펑크헤어스타일의 근원 고찰 -닭 볏 머리형을 중심으로-)

  • Lee, Yon-Hee;Kim, Ju-Ae
    • Journal of the Korean Society of Clothing and Textiles
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    • v.29 no.2
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    • pp.242-253
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    • 2005
  • The objective of this research is to identify and examine the punk hair styles which, with their various, rather vague names, help to describe the twentieth century subordinate culture or subculture and also their place today as one of the mainstream male hair trends. The scope of this research will stretch to include also: North-east and around that areas native Americans'hair styles which, are thought to have strong links with the Punk hair tend. The focus of this research will remain with the so-called Mohican or Mohawk hair styles(collectively referred to as Punk styles), which have originated mainly from native American warrions residing in North-east and South-east region of the United States. This study clarified a few questions in doubt concerning the origin of cockcomb hairstyle. Firstly, the cockcomb hairstyle known to represent punk hairstyle was influenced the American Indian's Roach style. Secondly, since Roach style is referred as Mohawk tribe's hairstyle in some refernces, the view of seeing cockcomb hairstyle as a Mohawk style is considered more persuasive. Thirdly, although Roach style was a usual hairstyle through North-east and South-east region of the United States, the people in South-east region did Roach hair style because of the North-east's influences. Lastly alike the Punkers had several kinds of cockcomb hairstyle. American Indians'Roach style also differed in shape concerning of their regions and their kindred. In addition, the reason why the most common term to refer punk hairstyle became Mohican is considered as that the film 'Last Mohican' has influenced on it. That film can appeal their history and play a good role of mediator to let the public know better about themselves, 'Mohican' naturally became the name of the specific hair style.

Physicochemical Properties of Cross-linked Rice Starches (가교화 쌀 전분의 이화학적 특성)

  • Choi, Hyun-Wook;Chung, Koo-Min;Kim, Chung-Ho;Moon, Tae-Hwa;Park, Cheon-Seok;Baik, Moo-Yeol
    • Applied Biological Chemistry
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    • v.49 no.1
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    • pp.49-54
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    • 2006
  • Physicochemical properties of cross-linked rice starches were investigated. Swelling power of cross-linked rice starch increased at relatively lower temperature $(60^{\circ}C)$ than native rice starch $(70^{\circ}C)$. Cross-linked rice starch showed lower solubility $(1.7{\sim}6.1%)$ than native rice starch $(2.2{\sim}13.8%)$ and solubility is not significantly different with the amount of phosphorus oxychloride. Pasting temperature $(69.2{\sim}70.6^{\circ}C)$ and peak viscosity $(2,874{\sim}3,175\;cp)$ of cross-linked rice starch were lower than native starch $(71.6^{\circ}C,\;3,976\;cp)$, but holding strength $(2,177{\sim}2,708\;cp)$ and final viscosity $(3,424{\sim}3,826 \;cp)$ of cross-linked rice starch were higher than native starch (1,000 cp, 2,312 cp). DSC thermal transitions of cross-linked rice starches were shifted to a lower temperature than native rice starch but there was no significant difference in gelatinization enthalpy between native and cross-linked rice starches. X-ray diffraction pattern of both native and cross-linked rice starches showed typical A-type crystal indicating that cross-linking had not affected the crystalline region of starch.

Site Environment and Morphology Characteristics of Native Bermudagrass (Cynodon spp.) Ecotypes in Korea (국내에서 수집된 버뮤다그래스의 입자환경 및 형태적 특성)

  • Bae, Eun-Ji;Lee, Kwang-Su;Park, Nam-Chang;Lee, Sang-Myung;Shin, Hyun-Cheol;Yang, Geun-Mo
    • Asian Journal of Turfgrass Science
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    • v.25 no.1
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    • pp.11-16
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    • 2011
  • This study was conducted to identify the morphological characteristics and variations level by site environment of native bermudagrass (Cynodon spp.) from costal and island region in South Korea. Soil chemical properties and morphological characteristics were investigated. There were significant differences in plant height, leaf width, leaf length, cotton on leaf blade, stolon, and number of seed per spike depending on where they were collected from natural habitat. We have discovered a variety of variation among the investigated traits in Korean native bermudagrass ecotypes. There were broad leaf and fine leaf types of native bermudgarass in S. Korea. Adaptability was in very high on inadequate environment in bermudagrass with broad leaf types, it has also been suggested that management worth in terms of use. These results may provide basic information for bermudagrass breeding development and the collected types during this investigation would be worth being preserved as genetic resources for further breeding purposes.

A Study on the Origin of the Native Plant's Name in Korea (한국(韓國) 자생식물명(自生植物名)의 유형(類型) 분석(分析))

  • Park, In Hwan
    • Current Research on Agriculture and Life Sciences
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    • v.12
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    • pp.1-7
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    • 1994
  • This paper analyzed the linguistic origin of the korean plant's name to give the better understanding of korean plants through the botanical names of native plants. In this study, a book "Flora of Korean" was used for analyzing plant's names. Some of the results were summerized as follows. Names of native plants in Korea were derived from animal and botanical were highest rate as 23.6 percent. And another names were composed of form of plants, local region, imagination, human beings and appearance of plant, each rate was 19.6 percent, 17.9 percent, 15.0 percent, 14.2 percent and 8.3 percent, respectively. Although the rate of name derived from botanical components was lowest, the number was 75.

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Preparation and Characterization of PEG-impregnated Aloe Gel through DIS Processing of Aloe vera Leaf Slice (DIS 공정에 의한 Polyethylene Glycol 함침 알로에 베라 겔의 제조 및 특성화)

  • Kwon, Hye Mi;Hur, Won;Lee, Shin Young
    • KSBB Journal
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    • v.28 no.6
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    • pp.356-365
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    • 2013
  • The novel Aloe gels were prepared with dewatering and impregnation by soaking (DIS) processing of Aloe vera leaf slice at four different temperatures (25, 35, 45 and $55^{\circ}C$), using dehydration solution of 40% (w/v) polyethylene glycol (PEG4000). The PEG-impregnation to Aloe vera leaf slice during DIS was observed depending on immersion temperature, and the PEG-impregnated Aloe vera gel (PEG-i-AVG) obtained was characterized using $^1H$ NMR, FT-IR, GPC, XRD and TGA. The PEG-i-AVG had the higher levels of Aloe bioactives (glucomannan and O-acetyl contents) and better quality indices by $^1H$ NMR and FT-IR spectroscopy than those of native Aloe gel. Also, the obtained Aloe gel maintained the bimodal patterns in higher molecular weight region by GPC indicating no degradation of polysaccharide from native Aloe gel. The result observed by SEM confirmed a surface modification by forming the porous structure, and TGA result exhibited better thermal stability than that of native Aloe gel. XRD result revealed that the crystalline structure in Aloe gel was led by incorporation of PEG. Significant decrease of %insolubility and high enhancement of water solubility index were observed, respectively, and highly ordered conformation such as a helix structure was also indicated by Congo red reaction. We concluded that the modification effect for enhancing function of native Aloe gel was successfully obtained by DIS process using PEG as a dehydrating agent. These results suggested that this DIS process had a high potential for developing a new minimally processed product from Aloe vera leaf.

Morphological study on suprachiasmatic nucleus of the Korean native goat (한국재래산양 시각교차위핵에 관한 형태학적 연구)

  • Song, Seung-hoon;Lee, Heungshik S.;Lee, In-se;Hwang, In-koo;Lee, Choong-hyun
    • Korean Journal of Veterinary Research
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    • v.40 no.4
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    • pp.665-670
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    • 2000
  • The present study was undertaken to investigate the morphological characteristics of the suprachiasmatic nucleus (SCN) of the Korean native goat by cresyl violet stain. The SCN was located ventrolateral to the third ventricle and dorsal to the optic chiasm. This nucleus was showed carrot form in longitudinal section. Its size was 1.8 mm in length, 0.9 mm in maximum height and 1.6 mm in maximum width. In coronal sections, the SCN shaped very thin plate in rostral part, but it was changed to sweet-potato form in middle part, and ornamental jade form in caudal part. The size of SCN was larger in caudal part than in rostral part. The size of the neuron of SCN was about $10{\mu}m$ in diameter with round or oval shape. The boundary of SCN was not firmly defined in caudal part because the neurons were dispersed into the hypothalamic region. It is concluded that the SCN of the Korean native goat has a morphological characteristics.

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