• Journal of Veterinary Clinics
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• v.23 no.2
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• pp.169-174
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• 2006

This work described 3 infection cases caused by Rhodococcus equi in foals between 3 and 5 months of age. The disease histories were not fully taken from local veterinarians. At least 1 sick foal has been treated with cephalothins followed by penicillins during approximately 1 week, but died without effectiveness and other foals rearing with the animal have been suffering from severe pneumonia which show high fever, laboring respiration, cough and/or nasal discharge. There were many abscessations into lungs of 2 foals in postmortem examination and another 1 sample was pus collected from abscess around the shoulder, indicating the osteomyelitis. Those bacteria were grampositive coryneform and were identified as a R. equi by a polymerase chain reaction (PCR) using primers for R. equi-specific vapA gene. The pathogens were usually resistant to penicillin, ampicillin, amoxycillin/clavulanic acid, cefazolin, clindamycin, sulfamethoxazol/trimethoprim, kanamycin, and tetracycline, while were sensitive to ciprofloxacin, norfloxacin, orfloxacin, gentamicin, erythromycin, neomycin, and vancomycin. Some more foals with respiratory symptoms in 1 horse farm were treated by orally administration with erythromycin during 2 weeks. Because the combination of erythromycin and rifampin has recommended as the treatment for R. equi infections in foals, the local equine veterinarian can choose those antibiotics for the treatment of this disease in future. However, another antimicrobial agent may be necessary if R. equi resistant to both agents is isolated.

• Journal of Physiology & Pathology in Korean Medicine
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• v.34 no.6
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• pp.309-318
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• 2020

Besides respiratory infection, COVID-19 has many neurological symptoms not only loss of smell and taste but also fatigue and brain fog. But it is a challenge to treat the neurological symptoms especially of anosmia and ageusia. In order to search for the therapeutic methods, the geographical diversity and pathological mechanisms of the COVID-19 and two symptoms were investigated from the latest clinical studies. Because the environmental conditions of the monsoon climate zone of East Asia and the Mediterranean and Oceanic climate zone of Italy, Britain, United States and tropical Brazil are different, each of diverse etiology and internal milieu should be considered differently in the treatment. SARS-CoV-2 exhibits the dampness-like characteristics and the olfactory and gustatory disorders are particularly more common than other flu or cold. and it tends to show features of damaging the lung qi of olfaction and heart-spleen qi of gustation. The mechanisms of olfactory and gustatory loss are various according to precursory, inflammatory, non-inflammatory and sequelar forms, so the therapeutic method should be designed for each period and pathology. If the process of inflammation arises from nasal and respiratory, olfactory epithelium to the central nervous structure by way of blood brain barrier, the treatment should be corresponded with the stage and depth of pathogen place. And if the olfactory loss is asymptomatic or in the initial stage, it can be applied intranasal topical scent therapy to relieve temporary locking of qi movement, but maybe also used in parallel together with herbs of relieving dampness toxin latent in the lung parenchyma.

• Journal of Korean Medical classics
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• v.35 no.2
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• pp.99-120
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• 2022

Objectives : To analyze symptoms of olfactory dysfunction caused by COVID-19 from a Korean Medical Perspective. Methods : Previous studies dealing with olfactory dysfunction accompanying COVID-19 were studied and analyzed for general characterization. Physiology and pathology of olfactory functions within the classical texts of Korean Medicine were collected and analyzed, through which symptoms of olfactory dysfunction in COVID-19 were examined. Results : Olfactory dysfunction manifested in high ratios in the early stages of confirmed COVID-19 cases, at times independent of other nasal symptoms such as blockage or discharge. There was a high chance of loss of taste being accompanied, while mental problems such as a tendency to have difficulty concentrating were present as well. In most cases, recovery took one to two weeks. From a Korean Medical perspective, physiology of olfactory function is closely linked to the Lungs, Ancetral Qi[宗氣], and the Heart, while its dysfunction could be explained by pathological factors such as Wind-Cold, Fire stagnation, Qi deficiency, Wind stroke, etc. Conclusions : In the context of external contraction disease[外感病], olfactory dysfunction could be caused by problems in the Lungs and Stomach that are responsible for breathing, or the Heart which is involved in recognizing and differentiating scent. General characteristics of COVID-19 imply it to be closely related to the Heart. In clinical application, overall symptoms need to be considered in diagnosis and treatment planning, after which further approaches could made to determine the problem to be of the Lung and Stomach, or of the Heart.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.25 no.1
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• pp.75-83
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• 2012

Objectives : The purpose of this study is to research the effect of bloodletting therapy and Alunitum-spread at palatine tonsil in acute tonsillitis. Methods : We reviewed medical records of 61 young patients of acute tonsillitis who had taken bloodletting therapy and Alunitum-spread from May 2003 to March 2011 in Samsung oriental medicine clinic. Results : There were 39 boys and 22 girls. Between 5 and 6 years-old group was more than the others. Between 3 and 4 days group was the first in duration of disease. Winter was the first and then spring, fall and summer in distribution of season. Between 9 and 10 days group was 22 patients, which was the first in duration of treatment. it was the first to have no history of acute tonsilitis group, and then cold, allergic rhinitis, laryngopharyngitis, acute tonsillitis and tympanitis. There were 41 patients who came to Samsung oriental medicine clinic the first and then western clinic, home remedy and other oriental clinic. Sore throat was the first sympton and then runny nose, high fever, nasal congestion and cough in companied symptom. Conclusions : Bloodletting therapy and Alunitum-spread were useful to improve acute tonsillitis.

• Proceedings of the Korean Environmental Health Society Conference
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• 2005.06a
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• pp.326-329
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• 2005

A worker who grinded the inner parts of camshafts for automobile engines using water-soluble metalworking fluid (MWF) for 14 years was diagnosed with sinusitis. We postulated that the outbreak of sinusitis could be associated with exposure to microbes contaminated in water-soluble MWF during the grinding operation. To suggest responsible agents for this outbreak, quantitative exposure assessment for chemical and biological agents and prevalence of work-related respiratory symptoms by questionnaire were studied. The exposure ranges of MWF mist (0.59 $mg/m^3$to 2.12 $mg/m^3$) measured during grinding exceeded 0.5 $mg/m^3$ of the recommended exposure limit (REL). Grinder's exposures to bacteria, fungi and endotoxins were also generally higher than not only the proposed standards, but also those reported by several studies to identify the cause of respiratory effects. Statistical test indicated that the prevalence rate of reported symptoms related to nasal cavities showed no significant differences among the operations. Evaluation on grinding operation characteristics and quantitative exposure assessment indicated that repeated exposure to MWF mist including microbes contaminated from the use of water-soluble MWF may cause respiratory diseases like sinusitis or at least increase susceptibility to the development of sinusitis

• Clinical and Experimental Pediatrics
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• v.58 no.2
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• pp.73-76
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• 2015

Isolated sphenoid sinusitis is a rare disease in children, and its symptoms are often nonspecific and confusing. Rarely, severe headache can be the first or only symptom of isolated sphenoid sinusitis. New daily persistent headache (NDPH) is a form of chronic daily headache that may have features of both migraines and tension-type headaches. NDPH is difficult to diagnose and requires a multifaceted approach. Here, we report on a 10-year-old boy and an 11-year-old girl who both presented with typical NDPH symptoms. These patients had no nasal symptoms or signs of infection. Neither nonsteroidal anti-inflammatory drugs nor topiramate had any effect on the headaches. Their neurological and ophthalmological examinations were normal. The results of routine blood work, including thyroid function tests, inflammatory markers, complete blood count, tests for viral infection, and a metabolic panel, were normal. A brain magnetic resonance imaging scan showed isolated sphenoid sinusitis. Both patients' symptoms resolved completely after approximately 1 month of oral antibiotics for sinusitis.

• The Journal of Korean Medicine
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• v.27 no.1 s.65
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• pp.155-164
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• 2006

Objectives : The aim of this study is to review allergic rhinitis and to help make full use of oriental medical therapy in this disease. Methods : We investigated the published papers with the key word 'allergic rhinitis' and refered to several important old records Results : 1. Allegic rhinitis in Oriental Medicine is known as bigu, bunche and the main symptoms is rhinorrhea, sneezing, nasal obstruction. 2. The cause of allergic rhinitis in Oriental Medicine is dysfunctions of the spleen, lung and kidney systems bring weakness to the vital energy(正氣) making wind and cold(風寒邪氣) energy easy to intrude. 3. Determination of the patient's constitution and understanding of the weakness of spleen, lung and kidney systems helps improve the treatment rate, it is used to treat allergic rhinits with herbal medicines, acupunctures and so on. 4. In acupuncture therapy, the mainly used acupuncture points are 迎香(younghyang), 印堂(yindang), 鼻通(bitong), 上星(sangsung), 合谷(habgouk). Conclusions : The Oriental Medicine treatment principal of rhinitis is strengthening the body resistance and eliminating the pathogenic factors according to the individual characters of each patients and the symptoms.

• Korean Journal of Head & Neck Oncology
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• v.32 no.1
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• pp.49-52
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• 2016

The lobular capillary hemangioma (LCH) was previously known to pyogenic granuloma and is benign vascular lesion which grows rapidly on skin and mucosa. It arises from whole body, but oral and nasal cavities are most predilection sites in the head and neck area. The laryngeal LCH looks like a granulomatous lesion of posterior glottis and its common etiology are tracheal intubation and laryngopharyngeal reflux disease etc. The LCH in larynx can cause blood tinged sputum and lump sense. The lesions refractory to medical therapy or causing dyspnea may require surgical excision. A 74-year-old man who presented gradually aggravated dyspnea, lump sensation and hoarseness of one month came to our hospital. The stroboscopic examination revealed large well-margined glottic mass. It was excised with $CO_2$ laser and finally diagnosed as LCH. We present a rare unique case of glottic LCH with a review of literatures.

• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.4
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• pp.409-417
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• 2012

External pathogens such as wind, cold can easily invade the external parts of the body when host's external defense ability is not secure. Herein, we consider the underlying mechanisms against the external contraction at the body surface. During the early period after primary invasion, external defense mechanisms are gradually activated. The classic clinical manifestations are aversion to cold, fever, headache, generalized pain, and nasal congestion. This condition is called by invasion of external pathogen into the body surface. As the disease progress, lung qi is stagnated and thereby up-outward and downward movement action of lung become disturbed. Therefore, when doctor administrate formula to treat the exterior syndrome, doctor must keep in mind not only materia medica, but also underlying mechanisms through which many clinical symptoms appear.

• Radiation Oncology Journal
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• v.2 no.1
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• pp.71-79
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• 1984

During a 10 year periods, 42 patients with well-documented Midline Malignant Reticulosis were treated with local irradiation and followed for extended periods of time. 13 cases with systemic manifestation after irradiation illustrate the protean features of this disease. Although it commonly Presents in upper airway tracts such as nasal cavity and/or septum, soft palate and palatine tonsil, the lesion may be localized as well as diffuse. 2 cases among them showed systemic relapse on lung, pancreas and scrotum probably from either a multifocal or metastatic deposits. Another 3 eases were associated with systemic diseases such as stomach carcinoma, typhoid enteritis and CNI of fat tissue. Remained cases were diagnosed by clinical or radiological examination. Possibility of close relation to lymphoma with Midline Malignant Reticulosis are also suggested in 1 case. In Midline Malignant Reticulosis, the best results of treatment are obtained in localized lesion of the upper airway treated early with irradiation: A poorer outcome is associated with multifocal systemic involvement, which necessitates a systemic therapy.