• Title/Summary/Keyword: nano.bio fusion

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Excited State Dynamics of Curcumin and Solvent Hydrogen Bonding

  • Yang, Il-Seung;Jin, Seung-Min;Kang, Jun-Hee;Ramanathan, Venkatnarayan;Kim, Hyung-Min;Suh, Yung-Doug;Kim, Seong-Keun
    • Bulletin of the Korean Chemical Society
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    • v.32 no.spc8
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    • pp.3090-3093
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    • 2011
  • Curcumin is a natural product with antioxidant, anti-inflammatory, antiviral and antifungal functions. As it is known that the excited state intramolecular hydrogen transfer of curcumin are related to its medicinal antioxidant mechanism, we investigated its excited state dynamics by using femtosecond transient absorption spectroscopy in an effort to understand the molecule's therapeutic effect in terms of its photophysics and photochemistry. We found that stronger intermolecular hydrogen bonding with solvents weakens the intramolecular hydrogen bonding and decelerates the dynamical process of the enolic hydrogen. Exceptions are found in methanol and ethylene glycol due to their nature as simultaneous hydrogen bonding donor-acceptor and high viscosity solvent, respectively.

A Study on Estimation of Liquid Leakage Using Wide Angle Camera Based Angled of Arrival Algorithm in Bio Plant

  • Shin, Jaekwon;Mariappan, Vinayagam;Woo, Deokgun;Lee, Junghoon;Lee, Jisung;Kim, Minsoo;Kim, Jintae
    • International journal of advanced smart convergence
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    • v.7 no.1
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    • pp.1-6
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    • 2018
  • In addition to the instability of energy import costs caused by the depletion of petroleum resources, which is a representative energy resource, and the strengthening of various regulations such as the convention on climate change, the plant for bio energy production, which is being watched as the next generation energy, and became subject of various complaints. In order to solve this problem, the bio-plant is underground and the ground is parked, making the convenience and accessibility of citizens more and more accessible. In this situation, the development of bioenergy production technology also increases the risk factor in bioenergy production process. Accordingly this paper explains method about apply the wide angle camera based AOA algorithm to the bio plant to prevent the accidents from spreading due to the lack of facilities and safety devices and the aging of the facilities and suggests a technique that can quickly identify the location and direction when it occurs.

Green Synthesis of Nanoparticles Using Extract of Ecklonia Cava and Catalytic Activity for Synthetic Dyes

  • Kim, Beomjin;Song, Woo Chang;Park, Sun Young;Park, Geuntae
    • Journal of Environmental Science International
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    • v.29 no.12
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    • pp.1171-1184
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    • 2020
  • The green synthesis of inorganic nanoparticles (NPs) using biomaterials has garnered considerable attention in recent years because of its eco-friendly, non-toxic, simple, and low-cost nature. In this study, we synthesized NPs of noble metals, such as Ag and Au using an aqueous extract of a marine seaweed, Ecklonia cava. The formation of AgNPs and AuNPs was confirmed by the presence of surface plasmon resonance peaks in UV-Vis absorption spectra at approximately 430 and 530 nm, respectively. Various properties of the NPs were evaluated using characterization techniques, such as dynamic light scattering, transmission electron microscopy, energy-dispersive X-ray spectroscopy, Fourier transform infrared spectroscopy, and X-ray diffraction analysis. Phytochemicals in the seaweed extract, such as phlorotannins, acted as both reducing and stabilizing agents for the growth of the NPs. The green-synthesized AgNPs and AuNPs were found to exhibit high catalytic activity for the decomposition of organic dyes, including azo dyes, methylene blue, rhodamine B, and methyl orange.

Characterization of Biocompatible Lipid-Based Vesicles Contained with Medicinal Herb Extracts

  • Lee, Kyu-Jin;Park, Sun young;Park, Geuntae
    • Journal of Environmental Science International
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    • v.27 no.10
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    • pp.853-863
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    • 2018
  • In order to increase the medicinal herbs efficiency of drug delivery, vesicles contained with medicinal herbs were prepared by phosphatidylcholines and surface active agent. Vesicles loaded with medicinal herbs were characterized by UV-spectroscopy, Zetasizer. The antioxidant activity of vesicles was measured by DPPH assay and ABTS radical scavenging assays. Also, an analysis was conducted to determine the effects of anti-inflammatory of vesicles contained medicinal herbs. In addition, the whitening effects of vesicles contained medicinal herbs extract were studied via tyrosinase inhibition assay. The results of vesicles were as follows. Vesicles appeared an average diameter of approximatively 164-599 nm. All studied vesicles contained with medicinal herbs showed antioxidant, anti-inflammatory and whitening effects in a dose-dependent manner. Therefore, this experiment achieves its purpose of synthesizing of vesicles. In conclusion, we recommended that the vesicles loaded with medicinal herbs have ability for anti-aging materials. Specifically, it will apply to cosmetic ingredients.

The Comparison of Sponges and PLGA Scaffolds Impregnated with DBP on Growth Behaviors of Human Intervertebral Disc Cells (DBP 스폰지와 DBP/PLGA 지지체에서의 인간 디스크세포 거동분석 비교)

  • Lee, Seon-Kyoung;Hong, Hee-Kyung;Kim, Su-Jin;Kim, Yong-Ki;Song, Yi-Seul;Ha, Yoon;Lee, Dong-Won;Khang, Gil-Son
    • Polymer(Korea)
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    • v.34 no.5
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    • pp.398-404
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    • 2010
  • We fabricated sponge and poly(lactide-co-glycolide)(PLGA) scaffolds impregnated demineralized bone particle(DBP)(DBP/PLGA) and investigated proper condition to proliferation and phenotype maintenance of intervertebral disc(IVD) cells by comparison between DBP/PLGA scaffold and DBP sponge. DBP/PLGA scaffolds were prepared by solvent casting/salt leaching. Human IVD cells were seeded in scaffolds of two types. Cell viability and proliferation according to scaffolds were analyzed by WST assay and SEM. RT-PCR was assessed to measure mRNA expression of aggrecan and type II collagen of human IVD cells. In WST assay results, cell viability in scaffolds impregnated DBP/PLGA scaffold were higher than DBP sponge. We could observe that disc cell mRNA expressed better in DBP/PLGA scaffold than DBP sponge. We concluded that the using of DBP/PLGA in terms of scaffold fabrication for bio-disc with human IVD cells is helpful growth of disc cells maintenance of phenotypes.