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Effect of Chronic Inhibition of Nitric Oxide on Blood Pressure and Apoptosis in the Blood Pressure-Associated with Organs

  • Bae, Hyung-Joon
    • Biomedical Science Letters
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    • v.16 no.1
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    • pp.25-32
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    • 2010
  • Sprague-Dawley(SD) rats were orally administered with $N^G$-nitro-L-arginine methyl ester(L-NAME) which inhibits or blocks the production of nitric oxide from L-arginine in vascular endothelial cells and vessel tissue to statistically examine the effects of nitric oxide on some physiological changes such as blood pressure and heart rate, and to confirm the apoptosis induced by the suppressed nitric oxide activity in some related organs under light microscope. Systolic blood pressure significantly increased 28.5% by the chronic treatment of L-NAME for 8 weeks (P<0.001), no significant difference, however, was observed in heart rate between the control group and the L-NAME-treated group regardless of their age. Hematoxylin-eosin staining showed some histological alterations only in kidney among the examined organs; heart, liver, pancreas, and adrenal gland from the L-NAME-treated group. TUNEL (terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling) test showed a strong positive reaction, representing that the chronic treatment of L-NAME facilitates apoptosis, in the cortex and medulla of kidney, but not any significance detectable in the other organs. These results conclude that chronic treatment of L-NAME significantly increases blood pressure, and that the followed inhibition of nitric oxide synthesis occurs a typical inducement of apoptosis in kidney.

목록에 있어서의 일본인명 표기-<대한민국출판물총목록>의 색인에 나타난 표기를 중심으로-

  • 김영귀
    • Journal of Korean Library and Information Science Society
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    • v.20
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    • pp.285-315
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    • 1993
  • Some conclusions can be derived from the study: 1. Person's name should be script by the one's mother tongue because of its uniqueness. 2. Japanese person's name should be script and pronounce their mother tongue for exchange and sharing of an academic information. 3. We can anticipate that Japanese language materials will be increase in near future. 4. The National Central Library which publish Korean National Bibliography must have to responsibility to lead other library. 5. The script of [Korean National bibliography] must contribute to standardization and national and Universal Bibliographic Control. 6. The area of education, newspaper, publishing are scripting Japanese person's name with script conversion schemes for Koreanization, devised by Ministry of Education. 7. The script of [Korean National Bibliography]'s name index can be used as authority file at selection of heading in library cataloging. 8. Most of libraries script Japanese person's name with Chinese character in Korean language pronunciation. 9. Korean Cataloging Rules (KCR) and Korean Machine Readable Cataloguing (KORMARC) description rules should be defined about the mother tongue script of Japanese person's name. 10. It is desirable to increase of credit of Readings in Japanese material course in college curriculum. 11. Because Japanese person's name is complex and variable that it is desirable to add Chinese character with mother tongue script.

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A Study on the Guideline of Authority Record for Heading Control of Personal Name (인명표목통제를 위한 전거레코드작성기준에 대한 연구)

  • 정옥경
    • Journal of Korean Library and Information Science Society
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    • v.32 no.4
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    • pp.257-282
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    • 2001
  • The purpose of this study is to suggest a rational guidelines of authority record for personal name heading control. It analyzes the Statement of Principles of ICCP, the headings of Korean Cataloging Rules and personal name heading of KORMARC on Disc. It also investigates the problems and suggests the possible improvements for headings of personal name. The rules for heading control retains the frame from headings of cataloging rules. The guidelines for heading control of personal name will be integrated in the rules for headings. To efficient retrieval, It suggests distinction of different persons of the same name and subject List.

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Disambiguation of Korean Names in References

  • Kim, Sungwon
    • Journal of Information Science Theory and Practice
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    • v.6 no.2
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    • pp.62-70
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    • 2018
  • One of the characteristics of academic writing is the inclusion of citations and references. As the development of reference styles used for international scholarly communication has mostly been led by Western academic societies, the reference styles developed in Western nations do not reflect the characteristics of Korean names. As a result, it is hard to distinguish Korean authors through citations based on Western reference styles, which in turn decreases the retrieval efficiency of relevant authors and ultimately the efficiency of scholarly communication. This paper intends to analyze author name disambiguation of Korean authors indicated according to Western reference styles. It aims to suggest the necessity for enhancing name disambiguation of Korean authors and revision of reference styles. Its ultimate goal is to increase the efficiency of scholarly communication through the improvement of name disambiguation of Korean authors. For this purpose, this study collected and analyzed name data of Korean researchers and compared name disambiguation of authors by reference style. Based on research results, this study confirmed a necessity for revising reference styles to improve name disambiguation of authors and suggested a necessity for research into the improvement of plans for revision.

Suggestion of Abbreviation for Korean Weeds Name (우리나라 잡초이름의 약어 제안)

  • Lee, In-Yong;Kim, Chang-Seog;Moon, Byung-Chul;Park, Jae-Eup;Oh, Se-Mun
    • Korean Journal of Weed Science
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    • v.30 no.3
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    • pp.308-321
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    • 2010
  • To increase of weed researches, abbreviations for Korean weeds name(tentatively named 'KSWS code', the Korean Society Weed Science code) of 433 species belonging to 68 families in arable land were suggested in this paper. The KSWS code was derived from Bayer code or/and modified. The KSWS code was composed of alphabetic 5 characters, namely 3 characters in generic name and 2 characters in specific name. And variable species's KSWS code was 1 characters in generic name and 1 characters in variable name.

Hate Speech and Usage of Japanese in Korean Insect Common Name (한국 곤충 국명 속에 나타난 혐오 표현과 일본어 잔재)

  • Kang, Seung-Ho;Kim, Sam-Kyu
    • Korean journal of applied entomology
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    • v.60 no.2
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    • pp.155-165
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    • 2021
  • There are 18,638 insect species recorded in Korea, representing 35.4% of Korean Biodiversity (52,628). In this study, we classified Korean common name into 11 categories (color, size, shape, plant, location, ecology, foreign language, personal name, native, physiology, positive/negative) and assigned every species into each categories and researched the meaning of Korean common names. We conducted further analysis on 506 cases of hate speech (disability, racial·regional·appearance discriminations). Also we analyzed 508 cases of Japanese expressions (person's name, place name, Japanese language), and proposed alternative words in case of inappropriate usages.

A Study of Domain Name Disputes Resolution with the Korea-U.S. FTA Agreement (한미자유무역협정(FTA)에 따른 도메인이름 분쟁해결의 개선방안에 관한 연구)

  • Park, Yu-Sun
    • Journal of Arbitration Studies
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    • v.17 no.2
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    • pp.167-187
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    • 2007
  • As Korea has reached a free trade agreement with the United States of America, it is required to provide an appropriate procedure to ".kr" domain name disputes based on the principles established in the Uniform Domain Name Dispute Resolution Policy(UDRP). Currently, Internet address Dispute Resolution Committee(IDRC) established under Article 16 of the Act on Internet Address Resources provides the dispute resolution proceedings to resolve ".kr" domain name disputes. While the IDRC's proceeding is similar to the UDRP administrative proceeding in procedural aspects, the Domain Name Dispute Mediation Policy that is established by the IDRC and that applies to disputes involving ".kr" domain names is very different from the UDRP for generic Top Level Domain (gTLD) in substantial aspects. Under the Korea-U.S. Free Trade Agreement(KORUS FTA), it is expected that either the Domain Name Dispute Mediation Policy to be amended to adopt the UDRP or the IDRC to examine the Domain Name Dispute Mediation Policy in order to harmonize it with the principles established in the UDRP. It is a common practice of cybersquatters to warehouse a number of domain names without any active use of these domain names after their registration. The Domain Name Dispute Mediation Policy provides that the complainant may request to transfer or delete the registration of the disputed domain name if the registrant registered, holds or uses the disputed domain name in bad faith. This provision lifts the complainant's burden of proof to show the respondent's bad faith because the complainant is only required to prove one of the three bad faiths which are registration in bad faith, holding in bad faith, or use in bad faith. The aforementioned resolution procedure is different from the UDRP regime which requires the complainant, in compliance with paragraph 4(b) of the UDRP, to prove that the disputed domain name has been registered in bad faith and is being used in bad faith. Therefore, the complainant carries heavy burden of proof under the UDRP. The IDRC should deny the complaint if the respondent has legitimate rights or interests in the domain names. Under the UDRP, the complainant must show that the respondent has no rights or legitimate interests in the disputed domain name. The UDRP sets out three illustrative circumstances, any one of which if proved by the respondent, shall be evidence of the respondent's rights to or legitimate interests in the domain name. As the Domain Name Dispute Mediation Policy provides only a general provision regarding the respondent's legitimate rights or interests, the respondent can be placed in a very week foundation to be protected under the Policy. It is therefore recommended for the IDRC to adopt the three UDRP circumstances to guide how the respondent can demonstrate his/her legitimate rights or interests in the disputed domain name. In accordance with the KORUS FTA, the Korean Government is required to provide online publication to a reliable and accurate database of contact information concerning domain name registrants. Cybersquatters often provide inaccurate contact information or willfully conceal their identity to avoid objection by trademark owners. It may cause unnecessary and unwarranted delay of the administrative proceedings. The respondent may loss the opportunity to assert his/her rights or legitimate interests in the domain name due to inability to submit the response effectively and timely. The respondent could breach a registration agreement with a registrar which requires the registrant to submit and update accurate contact information. The respondent who is reluctant to disclose his/her contact information on the Internet citing for privacy rights and protection. This is however debatable as the respondent may use the proxy registration service provided by the registrar to protect the respondent's privacy.

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Matching and Attribute Conflating Method for Linking the Digital Map with the Road Name Address System - Focused on the Road Centerline Layer - (수치지도의 도로명주소 체계 연계를 위한 매칭 및 속성 융합 방안 - 도로중심선 레이어를 중심으로 -)

  • Bang, Yoonsik;Ga, Chillo;Yu, Kiyun
    • Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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    • v.30 no.4
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    • pp.379-388
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    • 2012
  • The Road Name Address system has begun to be applied and widely used since 2011. However, the Digital Map, or the national representative basic map, has no reference to the Road Name Address system. It causes some difficulties to use the Digital Map under the Road Name Address system. In this paper, we suggest a method for generating the expanded Digital Map by adding information about Road Name Address system into the objects of the Digital Map. First, object matching pairs between the road section layer from the Road Name Address Map and the road centerline layer from the Digital Map are found. Then attributes to be copied from the Road Name Address map to the Digital Map are extracted by comparing their attribute tables. Finally the extracted attributes are copied from the Road Name Address Map to the Digital Map. The expanded road centerline layer of the Digital Map then has attributes about road name according to the Road Name Address system, so that the georeferencing of the Digital Map according to the Road Name Address system becomes possible.

A Study on the Name of East Sea in the Francophone Media Source (불어권 언론 매체의 동해 표기 명칭 고찰)

  • Lim, Eunjin;Yi, Saangkyun
    • Journal of the Korean association of regional geographers
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    • v.22 no.4
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    • pp.745-760
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    • 2016
  • The name of a place represents the social and political power relations as well as showing a certain physical space. In particular, the East Sea is not only a representative name of areas represent our country, but also the name of place being in competition with the Sea of Japan internationally. Korea is committed in many ways to spread the name of East Sea in the international community, and gradually expand its name power. The purpose of this study was to investigate the names used in the newspapers and broadcasting in Francophone countries except France by analyzing the newspaper articles and broadcasting contents, and to illuminate how the names of the East Sea produced in France, and the discussion about the names were diffused in Francophone countries and what kind of influence they had on those countries. This study selected Algeria in North Africa, Belgium and Luxembourg in West Europe, and Quebec in Canada for the research areas. As a result, while Algeria in North Africa and Luxembourg are showing inhospitality to the name East Sea, Belgium and Quebec are taking a flexible attitude toward this name. In general, most Francophone countries are provided with press releases from AFP in France. Even in same article provided by AFP, The result shows that some media stick to use the name Sea of Japan solely, and others demonstrate a will to use both name East Sea and Sea of Japan simultaneously. This study was able to show that the diffusion and spread of the place name was significantly influenced by social, political interests and powers, the mess geopolitics in pop cultural materials.

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Involvement of nitric oxide and prostanoid on the endothelium -dependent vasodilatation by acetylcholine in the isolated rabbit renal artery (토끼 적출 신동맥에 있어서 acetylcholine에 의한 내피세포 의존성 이완작용에 대한 nitric oxide와 prostanoid의 연관성)

  • Kim, Joo-heon;Shim, Cheol-soo;Jeon, Seok-cheol
    • Korean Journal of Veterinary Research
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    • v.41 no.3
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    • pp.299-304
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    • 2001
  • The effect of the nitric oxide synthase(NOS) inhibitor, $N^{G}$-nitro-L-arginine methyl ester (L-NAME), and the prostanoid synthesis inhibitor, indomethacin, on the vasodilatation produced in response to acetylcholine(Ach) on the isolated rabbit renal artery was examined. The vasodilatory reponses to Ach($10^{-8}-3{\times}10^{-5}M$) were completely absent in thevessel which the endothelium had previous been removed. L-NAME($10^{-4}M$) significantly reduced the vasodilatory reponse to the Ach($10^{-8}-3{\times}10^{-5}M$). When L-arginine ($10^{-3}M$) was also present in the organ bath along with L-NAME($10^{-4}M$), this inhibitory effect of L-NAME ($10^{-4}M$) on the vasodilatory response to Ach ($10^{-8}-3{\times}10^{-5}M$) was significantly attenuated, Indomethacin ($10^{-6}M$) did not significantly affect the vasodilatory responses to Ach ($10^{-8}-3{\times}10^{-5}M$). The inhibition by L-NAME ($10^{-4}M$) and indomethacin ($10^{-6}M$) on vasodilatory response to Ach was significantly greater than the inhibition due to L-NAME ($10^{-4}M$) alone. The present study has established that Ach induce relaxation via and endothelium-dependent mechanism, this relaxation to Ach involves both nitric oxide(NO) and prostanoid in the isolated rabbit renal artery.

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