• Journal of the Korean Society for Precision Engineering
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• v.21 no.6
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• pp.160-166
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• 2004

In this study, a new algorithm, named as Contour Offset Algorithm(COA) is developed to fabricate precise features or patterns in the range of several micrometers by nano replication printing(nRP) process. In the nRP process, a femto-second laser is scanned on a photosensitive monomer resin in order to induce polymerization of the liquid monomer according to a voxel matrix which is transformed from the bitmap format file. After polymerization, a droplet of ethanol is dropped to remove the unnecessary remaining liquid resin and then only the polymerized figures with nano-scaled precision are remaining on the glass plate. To obtain more precise replicated features, the contour lines in voxel matrix should be modified considering a voxel size. In this study, the efficiency of the proposed method is shown through two examples in view of accuracy.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.19 no.6
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• pp.3-15
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• 2009

Recently, Wu proposed a three small classes of finite fields $F_{2^n}$ for low-complexity bit-parallel multipliers. The proposed multipliers have low-complexities compared with those based on the irreducible pentanomials. In this paper, we propose a new Repeated Polynomial(RP) for low-complexity bit-parallel multipliers over $F_{2^n}$. Also, three classes of Irreducible Repeated polynomials are considered which are denoted, respectively, by case 1, case 2 and case3. The proposed RP bit-parallel multiplier has lower complexities than ones based on pentanomials. If we consider finite fields that have neither a ESP nor a trinomial as an irreducible polynomial when $n\leq1,000$. Then, in Wu''s result, only 11 finite fields exist for three types of irreducible polynomials when $n\leq1,000$. However, in our result, there are 181, 232, and 443 finite fields of case 1, 2 and 3, respectively.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.11 no.3
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• pp.146-153
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• 2012

RP system which is widely used to reduce the time of product development is to resolve the problem of cutting work. It is a method using laminated thin films to produce many forms. The RP equipment used for this experiment is FDM system. This can produce 3D model with using 3D CAD designed file within a relatively short time. Not only this, this system also through 3D file preparation, 3D product manufacture, removal support these 3 step operating process can easily produce goods, but product can be different from original design. This research has been conducted to minimize this error. To apply to the circular product made a circular specimen and measured several times with 3D scanner and find out average 99.622% of accuracy. This result is applied to RP system, and with this changed design produced a specimen, and found out the accuracy is increased to 99.958%. If this is applied to circular products, we can produce more precise products with less process.

• Journal of the korean society of oceanography
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• v.39 no.1
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• pp.20-25
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• 2004

The Yellow Sea is known to be a very productive region in terms of fisheries. However, its trophic status seems to be highly variable, ranging from oligotrophic to eutrophic, based on new production (NP) values. The NP and regenerated production (RP) values estimated from $^{15}N$-labelled nitrate and ammonium uptake in spring (April 1996) and winter (February 1997) during this study ranged from 0.05 to 19.8 mg $N m^{-2} d^{-1}$ and from 0.1 to 22.8 mg $N m^{-2}d^{-1}$, respectively. Our measurements and earlier observations suggested that NP in the Yellow Sea varied over the four orders of magnitude (range 0.05-180.9 mg $N m^{-2} d^{-1}$) temporally and spatially, and that RP (range 0.1-507.5 mg $N m^{-2}d^{-l}$) based on ammonium predominated during most period of the year, except in winter when both productions were low. The significant nitrogen uptake by phytoplankton below the euphotic zone and episodic entrainment of phytoplankton from below the euphotic zone into the euphotic zone, and nitrite excretion and dissolved organic nitrogen release during nitrate uptake might explain the apparent dominance of RP in the Yellow Sea.

• Toxicological Research
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• v.32 no.4
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• pp.269-274
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• 2016

The potency of influenza vaccine is determined based on its hemagglutinin (HA) content. In general, single radial immunodiffusion (SRID) assay has been utilized as the standard method to measure HA content. However, preparation of reagents for SRID such as antigen and antibody takes approximately 2~3 months, which causes delays in the development of influenza vaccine. Therefore, quantification of HA content by other alternative methods is required. In this study, we measured HA contents of H1N1 antigen and H1N1 influenza vaccine by reverse phase-high performance liquid chromatography (RP-HPLC) methods. The presence of HA1 and HA2 was investigated by silver staining and Western blot assay. In addition, accuracy and repeatability of HA measurement by RP-HPLC were evaluated. Comparison of HA concentration by SRID and RP-HPLC revealed a precise correlation between the two methods. Our results suggest that RP-HPLC assay can replace SRID in the event of a pandemic flu outbreak for rapid vaccine development.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.4
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• pp.1037-1049
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• 2003

Numerous lines of evidence indicate that some of the neurotoxicity associated with Alzheimer's disease (AD) is due to proteolytic fragments of the amyloid precursor protein (APP). Most research has focused on the amyloid 6 (M). However, the possible role of other cleaved products of APP is less clear. Lately It has been reported that a recombinant carboxy-terminal 105 amino acid fragment (CT105) of APP induced strong nonselective inward currents in Xenopus oocyte. In a brain with Alzheimer's disease (AD), to investigate the roles of carboxyl-terminal fragment (CT105) of amyloid precursor protein (APP) in apoptosis processes possibly linked to neurodegeneration associated with AD, we examined the effects of the CT of APP with 105 amino acid residues (CT105) on the alteration of apoptosis triggers in neubroblastoma cells. We have investigated whether Radix Polygalae and Rhizoma Acori Graminei mixture extract (RP+RAG) inhibits CT105-induced apoptosis of neuroblastoma cells. We found that RP+RAG inhibits CT105-induced apoptosis in SK-N-SH cells. Treatment of the cells with RP+RAG inhibited CT105-induced DNA fragmentation and Tunel assay of nuclear chromatin and inhibited the caspase-3 expression in SK-N-SH cells. As the result of this study, In RP+RAG group, the apoptosis in the nervous system is inhibited, the repair against the degerneration of neuroblastoma cells by CT105 expression is promoted. These results indicate that RP+RAG possess strong inhibitory effect of apoptosis in the nervous system and repair effect against the degeneration of neuroblastoma cells by CT105 expression

• Current Optics and Photonics
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• v.1 no.6
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• pp.613-617
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• 2017

Due to optimal advances such as chromatic performance, durability, low power consumption, high efficiency, long-lifetime, and excellent environmental friendliness, white LEDs (WLEDs) are widely used in vehicle front lighting, backlighting, decorative lighting, street lighting, and even general lighting. In this paper, the remote packaging WLEDs (RP-WLEDs) with bi-layer red-emitting $Sr_2Si_5N_8:Eu^{2+}$ and yellow-emitting YAG:Ce phosphor was proposed and investigated. The simulation results based on the MATLAB software and the commercial software Light Tools indicated that the color rendering index (CRI) of bi-layer phosphor RP-WLEDs had a significant increase. The CRI had a considerable increase from 72 to 94. In conclusion, the results showed that bi-layer red-emitting $Sr_2Si_5N_8:Eu^{2+}$ and yellow-emitting YAG:Ce phosphor could be a prospective approach for manufacturing RP-WLEDs with enhanced optical properties.

• Archives of Pharmacal Research
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• v.28 no.12
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• pp.1386-1391
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• 2005

This study examined the role of Kupffer cells in altering the hepatic secretory and microsomal function during ischemia and reperfusion (ls/Rp). Rats were subjected to 60 min of hepatic ischemia, followed by 1 and 5 h of reperfusion. Gadolinium chloride ($GdCl_{3}$, 7.5 mg/kg body weight, intravenously) was used to inactivate the Kupffer cells 1 day prior to ischemia. Is/Rp markedly increased the serum aminotransferase level and the extent of lipid peroxidation. $GdCl_{3}$ significantly attenuated these increases. Is/Rp markedly decreased the bile. flow and cholate output, and $GdCl_{3}$ restored their secretion. The cytochrome P450 content was decreased by Is/Rp. However, these decreases were not prevented by $GdCl_{3}$. The aminopyrine N-demethylase activity was decreased by Is/Rp, while the aniline p-hydroxylase activity was increased. $GdCl_{3}$ prevented the increase in the aniline p-hydroxylase activity. Overall, Is/Rp diminishes the hepatic secretory and microsomal drug-metabolizing functions, and Kupffer cells are involved in this hepatobiliary dysfunction.

• Journal of Aerospace System Engineering
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• v.14 no.5
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• pp.107-121
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• 2020

The performance analysis of the small satellites launch vehicle using the electric pump cycle as the upper stage engines was performed. The first stage is the launch vehicle that uses the test launch vehicle of the Korea Space Launch Vehicle II and the second stage employs elecpump cycle engine that uses liquid methane and kerosene (RP-1) as fuel. A model for the mass estimation was presented and the analysis was conducted for the range of thrust of 20 to 40 kN and combustion pressure of 3 to 6 MPa with a nozzle expansion ratio of 60 to 100. The mixture ratio with the maximum velocity increment was calculated and the performance of the LEO and SSO payload were calculated from the stage mass estimation. In both the cases, liquid methane, and RP-1 showed maximum payload for 20 kN thrust, 3 MPa combustion pressure, and the nozzle expansion ratio of 100, with a mixture ratio of 3.49 for liquid methane and 2.75 for RP-1. In addition, the ditching points of the first stage and the fairing in the LEO mission were analyzed using ASTOS.

• Journal of the Korean Society of Food Science and Nutrition
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• v.24 no.3
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• pp.440-445
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• 1995

The antimutagenic effects of juices from green pepper(GP), red pepper leaf(RPL), red pepper(RP) and sweet pepper(SP) were examined by the Ames method using Salmonella typhimurium TA100. The juice supernatants of GP, RPL and RP showed antimutagenic activities against afltoxin B1(AFB1) in Salmonella typhimurium TA 100. The juice supermatants of GP and RPL also exhibited the inhibitory effects(p<0.05) to the mutagenicities induced by N-methyl-N'-nitro-N-nitrosoguanidine(MNNG) and 4-nitro-quinoline-1-oxide(4-NQO). The juice of RP showed antimutagenic activities against indirect mutagen of AFB1, however, the activity was reduced at higher concentration(5.0%), furthermore, as the adding concentration of sample increased to 5.0%, it exhibited slight comutagenicith on direct mutagen of MNNG. Theantimutagenic activities of GP and RPL juices were reduced significantly after heating at 100℃ for 20min, supposing that the antimutagenic compound(s) in the juices were heat labile.