• Title/Summary/Keyword: multiple weights

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AllEC: An Implementation of Application for EC Numbers Prediction based on AEC Algorithm

  • Park, Juyeon;Park, Mingyu;Han, Sora;Kim, Jeongdong;Oh, Taejin;Lee, Hyun
    • International Journal of Advanced Culture Technology
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    • v.10 no.2
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    • pp.201-212
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    • 2022
  • With the development of sequencing technology, there is a need for technology to predict the function of the protein sequence. Enzyme Commission (EC) numbers are becoming markers that distinguish the function of the sequence. In particular, many researchers are researching various methods of predicting the EC numbers of protein sequences based on deep learning. However, as studies using various methods exist, a problem arises, in which the exact prediction result of the sequence is unknown. To solve this problem, this paper proposes an All Enzyme Commission (AEC) algorithm. The proposed AEC is an algorithm that executes various prediction methods and integrates the results when predicting sequences. This algorithm uses duplicates to give more weights when duplicate values are obtained from multiple methods. The largest value, among the final prediction result values for each method to which the weight is applied, is the final prediction result. Moreover, for the convenience of researchers, the proposed algorithm is provided through the AllEC web services. They can use the algorithms regardless of the operating systems, installation, or operating environment.

Site-Specific Error-Cross Correlation-Informed Quadruple Collocation Approach for Improved Global Precipitation Estimates

  • Alcantara, Angelika;Ahn Kuk-Hyun
    • Proceedings of the Korea Water Resources Association Conference
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    • 2023.05a
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    • pp.180-180
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    • 2023
  • To improve global risk management, understanding the characteristics and distribution of precipitation is crucial. However, obtaining spatially and temporally resolved climatic data remains challenging due to sparse gauge observations and limited data availability, despite the use of satellite and reanalysis products. To address this challenge, merging available precipitation products has been introduced to generate spatially and temporally reliable data by taking advantage of the strength of the individual products. However, most of the existing studies utilize all the available products without considering the varying performances of each dataset in different regions. Comprehensively considering the relative contributions of each parent dataset is necessary since their contributions may vary significantly and utilizing all the available datasets for data merging may lead to significant data redundancy issues. Hence, for this study, we introduce a site-specific precipitation merging method that utilizes the Quadruple Collocation (QC) approach, which acknowledges the existence of error-cross correlation between the parent datasets, to create a high-resolution global daily precipitation data from 2001-2020. The performance of multiple gridded precipitation products are first evaluated per region to determine the best combination of quadruplets to be utilized in estimating the error variances through the QC approach and computation of merging weights. The merged precipitation is then computed by adding the precipitation from each dataset in the quadruplet multiplied by each respective merging weight. Our results show that our approach holds promise for generating reliable global precipitation data for data-scarce regions lacking spatially and temporally resolved precipitation data.

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Factors Associated with Depression in Older Adults Living Alone during the COVID-19 Pandemic

  • Hong, Eun Hye;Lee, Kyung Hee
    • Research in Community and Public Health Nursing
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    • v.33 no.4
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    • pp.418-431
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    • 2022
  • Purpose: The aims of this study were to examine the rate of depression among older adults living alone and to identify factors associated with depression in older adults living alone during the COVID-19 pandemic. Methods: A secondary data analysis was performed using data from the 2020 Korea Community Health Survey. The study participants were 18,824 older adults aged 65 years and over living alone. The data of the complex sample design was analyzed with consideration for weights, stratification, and clustering. Complex sample multiple logistic regression was conducted to identify factors associated with depression in older adults living alone during the COVID-19 pandemic. Results: The results showed that the rate of depression in older adults living alone was 6.3%. Older adults living alone with decreased physical activity, decreased hours of sleep, and an increased or similar frequency of meeting with friends or neighbors were found to be more likely to have depression. In terms of factors related to the practice of COVID-19 infection prevention and control rules, not disinfecting regularly and not wearing a mask indoors were related to depression. For health-related factors, fair or poor self-rated health status, not having breakfast every day, and feeling stressed were related to depression. Conclusion: It is recommended to develop tailored interventions to prevent depression among older adults living alone by considering the factors related to their depression during the COVID-19 pandemic.

Indoor positioning system using Xgboosting (Xgboosting 기법을 이용한 실내 위치 측위 기법)

  • Hwang, Chi-Gon;Yoon, Chang-Pyo;Kim, Dae-Jin
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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    • 2021.10a
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    • pp.492-494
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    • 2021
  • The decision tree technique is used as a classification technique in machine learning. However, the decision tree has a problem of consuming a lot of speed or resources due to the problem of overfitting. To solve this problem, there are bagging and boosting techniques. Bagging creates multiple samplings and models them using them, and boosting models the sampled data and adjusts weights to reduce overfitting. In addition, recently, techniques Xgboost have been introduced to improve performance. Therefore, in this paper, we collect wifi signal data for indoor positioning, apply it to the existing method and Xgboost, and perform performance evaluation through it.

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Association between obesity and high-sensitivity C-reactive protein in Korean adults without cardiovascular disease

  • Heashoon, Lee
    • Journal of Korean Biological Nursing Science
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    • v.25 no.1
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    • pp.32-42
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    • 2023
  • Purpose: This study aimed to investigate the association between obesity and high-sensitivity C-reactive protein (hs-CRP) levels in Korean adults without cardiovascular disease (CVD). Methods: The subjects were 3,634 adults, and data were extracted from the seventh Korea National Health and Nutrition Examination Survey (KNHANES VII-3). A complex sampling design analysis was applied to reflect the stratified and clustered weights. The data were analyzed using the complex sample Rao-Scott chi-square test and multiple logistic regression analysis (in SPSS for Windows version 26.0). Obesity, according to body mass index (BMI), was defined as obesity (BMI = 25-29.9 kg/m2), high obesity (BMI = 30-34.9 kg/m2), and super-high obesity (BMI ≥ 35 kg/m2), and abdominal obesity (AO) was defined as a waist circumference (WC) ≥ 90 cm in males and WC ≥ 85 cm in females. Results: The odds ratios for moderate CVD risk (hs-CRP; 1-3 mg/dL) were 2.21, 4.16, and 7.13 in the obesity, high obesity, and super-high obesity groups, respectively, compared to the normal BMI group. The odds ratio for moderate CVD risk was 2.18 in males with AO and 1.88 in females with AO. The odds ratios for high CVD risk (hs-CRP > 3 mg/L) were 4.40 and 17.55 in the high obesity and super-high obesity groups, respectively, compared to the normal BMI group. Conclusion: This study provides evidence that early detection and prevention programs for CVD should include obesity-related interventions aiming to modulate hs-CRP.

Endoscopic Findings of Upper GI Bleedings in Full Term Newborn Infants (만삭아에서 발생한 상부 위장관 출혈의 내시경적 진단과 치료)

  • Rhim, Suk-Ho;Lee, Hye-Kyung;Min, Yong-Sik;Kim, Han-Jin;Kim, Young-Chang
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.4 no.2
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    • pp.142-147
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    • 2001
  • Purpose: We are going to establish the efficacy of endoscopic examinations in diagnosing and treating upper GI bleeding in full term neonates. Methods: We retrospectively reviewed newborns who underwent endoscopic examination because of hematemesis from July 1998 to April 2001. Results: Gestational ages were between 38 and 41weeks, and birth weights were between 2,730 and 3,400 gm. Total of 9 patients were reviewed. Endoscopic examination revealed gastric ulcer in 6 cases, multiple erosions in 2 cases and negative finding in 1 case. All 6 gastric ulcers were multiple and among them 2 patients endoscopic hemostatic therapy. No complication due to the procedure was noticed. Five patients recieved transfusions. All 9 cases were cured through conservative and endoscopic therapy without recurrence. Conclusion: The common cause of upper GI hemorrhage in newborns with no preceding disease turns out to be multiple gastric ulcers and the prognosis is good. The endoscopic approach is useful in diagnosing and treating upper GI bleeding in newborns.

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Multiple Regression Analysis to Estimate the Unit Price of Hanwoo (Bos taurus coreanae) Beef

  • Eum, Seung-Hoon;Park, Hu-Rak;Seo, Jakyeom;Cho, Seong-Keun;Hur, Sun-Jin;Kim, Byeong-Woo
    • Food Science of Animal Resources
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    • v.37 no.5
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    • pp.663-669
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    • 2017
  • This study were estimated the contribution of carcass traits to unit price, to analyze the marbling score as a categorical variable rather than a numerical variable, and to develop an optimal model that also includes the holiday effect and the raising period. The data for this study were acquired from the Quality Evaluation of the Korea Institute for Animal Products, and consisted of the trading records of 1,613,699 heads at 12 wholesale markets from 2010 to 2014. The unit price of a cow was estimated from the following parameters: -52.50 Won/mm, $8.93Won/cm^2$, 7.20 Won/kg, and -1.04 Won/day for backfat thickness, eye muscle area, carcass weight, and raising period, respectively. Parameters for the dummy variables of marbling scores varied from 0 to 8328.74 Won/kg, which means that each marbling score grade had a different price value. The unit price of a steer was estimated from the following parameters: - 92.12 Won/mm, $20.22Won/cm^2$, 1.30 Won/kg, and -1.72 Won/day for backfat thickness, eye muscle area, carcass weights, and raising period, respectively. Parameters for dummy variables of marbling scores varied from 0 to 7338.80 Won/kg, which means that the grades of each marbling score had different price values. The unit price of sales during traditional holidays was significantly higher (827.71 Won/kg for cows, and 645.15 Won/kg for steers) than during non-holidays.We conclude that the use of categorical values for marbling scores would be needed to evaluate the price of Hanwoo beef using multiple regression analysis based on carcass traits and environmental factors.

DEA Models and Application Procedure for Performance Evaluation on Governmental Funding Projects for IT Small and Medium-sized Enterprises with Exogenously Fixed Variables of Corporate Competency (기업역량을 고려한 외생고정변수를 갖는 IT중소기업 정부자금지원정책 성과평가를 위한 DEA모형 및 활용절차)

  • Park, Sung-Min;Kim, Heon
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.33 no.5B
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    • pp.364-378
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    • 2008
  • Data Envelopment Analysis(DEA) models can be used for performance evaluation on governmental funding projects for IT small and medium-sized enterprises associated with multiple-outputs/multiple-inputs. In order to enhance the accuracy of DEA efficiency scores, DEA models with exogenously fixed variables are required where the corporate competency is taken into account. Additionally, it is necessary to use multiple DEA basic as well as extended models so as to relax the restriction on the performance evaluation to relying on a single DEA model. In this study; 1)a DEA data structure is designed including exogenously fixed variables representing corporate asset, revenue and the number of employees at the point in time that the governmental funding project concerned is initiated; 2)DEA basic as well as extended models are established according to the DEA data structure presented abovementioned; and 3)a case study is illustrated with an empirical testbed dataset. As for the DEA basic models, CCR, BCC, Super-efficiency model are adopted. The DEA extended models are developed based on the models associated with noncontrollable and nondiscretionary variables. In the case study, it is explained a comparison of DEA models and also major numerical outcomes such as efficiency scores, ranks derived from each DEA model are integrated using Analytic Hierarchy Process(AHP) weights. Performance significance with DEA efficiency scores between technical categories are tested based not only on parametric but also nonparametric single-factor analysis of variance method.

Comparison Study of Beam Pattern for FDD downlink CDMA Signals (FDD에서 하향링크 CDMA신호의 빔패턴 비교 연구)

  • Kim, Sang-Choon;Son, Kyung-Soo;Ha, Joo-Young;Lee, Sung-Mok;Jang, Won-Woo
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.11 no.2
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    • pp.358-365
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    • 2007
  • In this paper, the effects of transmit beamforming on downlink performance in DS-CDMA communication systems are investigated. The uplink and downlink in FDD systems use different carrier frequencies. If the downlink uses the same weighting vectors as the uplink, the antenna beam for downlink is formed with certain DOA shift and it thus affects the beamforming gain. So, the impacts of different frequencies on the downlink beam patterns are studied. One possible algorithm to convert uplink beamforming weights to downlink, which is called frequency-calibrated processing, is also evaluated to reduce the degradation of downlink performance due to different frequencies. Under frequency selective channels, the downlink chooses a PUPW beamforming scheme when the uplink employs a PPPW vectors. To form a beam pattern for a PUPW after combining the downlink PPPWs converted from the uplink PPPWs, three approaches are studied. One method is to consider only one dominant path and thus obtain a single main-beam. In the others, multiple-beams weighted with the magnitudes of all paths and equally weighted with all paths are constructed.

Effects of Neonatal Exposure of Di (n-butyl) Phthalate and Flutamide on Male Reproduction in Rats

  • Kim, Tae-Sung;Kim, Hyung-Sik;Shin, Jae-Ho;Lee, Su-Jung;Moon, Hyun-Ju;Kang, Il-Hyun;Kim, In-Young;Seok, Ji-Hyun;Oh, Ji-Young;Han, Soon-Young
    • Proceedings of the Korean Society of Embryo Transfer Conference
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    • 2002.11a
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    • pp.109-109
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    • 2002
  • In recent reports, the multiple reproductive defects such as cryptorchidism, hypospadias, epididymal cysts, low sperm counts, and testicular cancers are increased in humans, and these changes were doubted by the chemicals with estrogenic or antiandrogenic activities in our environment. To compare the effects of neonatal exposure of di (n-butyl) phthalate and flutamide on the development of reproductive organs and to identify the specific mechanisms of these abnormalities related to the male reproducton, Sprague-Dawley neonate male rats were injected subcutaneously during 5-14 days after birth with corn oil (control), flutamide (0.05, 0.1, and 0.5 mg/animal) and DBP (5, 10, and 20 mg/animal). Animals were killed at 31 (immature) and 42 (pubertal) days of age respectively and blood was collected from abdominal aorta for serum testosterone analysis. Testes, epididymides, seminal vesicles, ventral prostate, levator ani plus bulbocavernosus muscle (LABC), cowpers glands and glans penis were weighed. Expression of steroid hormone receptors (AR and ER) was examined in the testes and ventral prostate. At 31 days of age, ventral prostate, seminal vesicles, LABC, and cowpers glands significantly decreased in the flutamide (0.5 mg/animal) and DBP (20 mg/animal), but serum testosterone levels were not changed. Flutamide slightly delayed the testes descent at the high dose (0.5 mg/animal), but DBP did not show any significant effect on the testes descent at all doses. DBP and flutamide decreased the expression of AR protein in the testes but did not affect the expression of ERa and ER protein in the testes. At 42 days of age, ventral prostate, seminal vesicles, and cowpers glands weights were still significantly decreased at the high dose of flutamide (0.5 mg/animal) and DBP (20 mg/animal), but the weights of testes and epididymides were not different. Serum testosterone decreased significantly in DBP treated animals and slightly, not significantly, in flutamide group. While DBP still significantly decreased the expression of AR protein in testis, flutamide recovered from downregulation of AR protein and did not affect the expression of ERa and ER protein in the testes. Based on these results, flutamide and DBP have shown several similar patterns in reproductive abnormalitis, but some marked differences which may be caused by different acting mechanism.

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