• 유체기계공업학회:학술대회논문집
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• 유체기계공업학회 2006년 제4회 한국유체공학학술대회 논문집
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• pp.367-370
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• 2006

Performances of multiple surrogate models are evaluated in a turbomachinery blade shape optimization. The basic models, i.e., Response Surface Approximation, Kriging and Radial Basis Neural Network models as well as weighted average models are tested for shape optimization. Global data based errors for each surrogates are used to calculate the weights. These weights are multiplied with the respective surrogates to get the final weighted average models. The design points are selected using three level fractional factorial D-optimal designs. The present approach can help address the multi-objective design on a rational basis with quantifiable cost-benefit analysis.

• 대한전자공학회:학술대회논문집
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• 대한전자공학회 2001년도 하계종합학술대회 논문집(1)
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• pp.89-92
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• 2001

In this paper, adaptive multi-stage parallel interference cancellation (PIC) receiver is considered for a multi-rate DS-CDMA system. In each stage of the adaptive multi-stage PIC receiver, multiple access interference (MAI) estimates are obtained using the sub-bit estimates from the Previous stage and the adaptive weights for the sub-bit estimates. The adaptive weights are obtained by minimizing the mean squared error between the received signal and its estimate through a least mean square (LMS) algorithm. It is shown that the adaptive multi- stage PIC receiver achieves smaller BER than the matched filter receiver, multi-stage PIC receiver, and multi-stage partial PIC receiver for the multi-rate DS-CDMA system in a Rayleigh fading channel.

• 한국경영과학회지
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• 제37권1호
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• pp.19-28
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• 2012

We consider a multi-agent scheduling problem such that each agent tries to maximize the weighted number of just-in-time jobs. Two objectives are considered : the first is to find the optimal solution for one agent with constraints on the other agents' weight functions, and the second is to find the largest set of efficient schedules of which corresponding objective vectors are different for the case with identical weights. We show that when the number of agents is fixed, the single machine case with the first objective is NP-hard in the ordinary sense, and present the polynomial- time algorithm for the two-machine flow shop case with the second objective and identical weights.

• 약학회지
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• 제48권4호
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• pp.247-253
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• 2004

We investigated the hypoglycemic effect of formula containing Euonymus alatus (EA) and Mori Folium (MF) in multiple low dose (MLD) streptozotocin (STZ)-induced diabetic rats. In order to iduce hyperglycemic state 25 mg/kg of STZ was injected intraperitoneally for 5 consecutive days. SD rats were randomly divided into diabetic control and treatment groups. Treatment groups were administered with either 250 mg/kg of EA and 250 mg/kg of MF (E1Ml), or 500 mg/kg of EA mixed with same dose of MF (E2M2) for 3 weeks. Blood glucose levels and body weights were measured every 5th or 6th day. E1Ml and E2M2 both significantly reduced food intake, water intake, and fasting blood and urine glucose levels as compared to those in diabetic control group in a dose dependent manner. Body weight in diabetic control group was increased slightly after 3 weeks. Treatment group, however, showed gradual increase in body weights during 3 week-period. While plasma insulin levels of the diabetic control group were decreased to the level of 387$\pm$14 pg/ml from 534$\pm$36 pg/ml, those levels in E1Ml and E2M2-treated groups were both markedly increased by 13% and 26%, respectively. Urine glucose levels in E1Ml and E2M2-treated groups were also remarkably reduced by 17 and 26% compared to the levels of diabetic control group. While expression of membrane-bound glucose transporter-4 (GLUT-4) protein in skeletal muscle was reduced by 45% in diabetic control compared to the normal control, GLUT-4 protein expressions in E1Ml and E2M2-treated groups were augmented by 2 and 3.5 times compared to the diabetic control, respectively. Pancreatic HE staining experiments showed that E2M2-treated group revealed much less infiltrated mononuclear cells, indicating that E2M2 efficiently blocked insulitis induced by multiple low dose streptozotocin. Taken together, we conclude that formula containing EA and MF may prevent or delay the development of hyperglycemia through overexpression of GLUT-4 protein in skeletal muscle and prevention of insulitis.

• 전기학회논문지
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• 제68권3호
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• pp.471-479
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• 2019

This research proposes a indoor magnetic map matching algorithm that improves the position accuracy by employing multiple magnetic sensors and probabilistic candidate weighting function. Since the magnetic field is easily distorted by the surrounding environment, the distorted magnetic field can be used for position mapping, and multiple sensor configuration is useful to improve mapping accuracy. Nevertheless, the position error is likely to increase because the external magnetic disturbances have repeated pattern in indoor environment and several points have similar magnetic field distortion characteristics. Those errors cause large position error, which reduces the accuracy of the position detection. In order to solve this problem, we propose a method to reduce the error using multiple sensors and likelihood boundaries that uses human walking characteristics. Also, to reduce the maximum position error, we propose an algorithm that weights according to their importance. We performed indoor walking tests to evaluate the performance of the algorithm and analyzed the position detection error rate and maximum distance error. From the results we can confirm that the accuracy of position detection is greatly improved.

• 한국강구조학회 논문집
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• 제29권6호
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• pp.467-477
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• 2017

현행 국내 교량 설계기준의 활하중 모형인 KL-510의 하중 효과를 실측된 통행자료로부터 통계적으로 추정한 트럭의 연행효과 및 국내외 관련 설계기준이 하중모형과 비교한다. 과적단속 전후에 고속도로에서 측정된 트럭의 중량 자료를 이용하여 설계기준의 활하중 모형 결정과 동일한 과정을 따라서 트럭 중량을 산정하여 그 하중효과를 KL-510과 비교하였다. KL-510은 운행제한중량을 초과하는 트럭을 일부 포함하는 자료로부터 추정한 트럭의 연행에 의한 하중효과와 매우 부합하는 결과를 보였다. KL-510은 미국 AASHTO LRFD의 활하중 모형과 일관성 있는 결과를 주며, 기존 하중 모형인 DB-24보다 하중효과의 비율이 균일하였다. 이 연구의 결과로 가상의 하중 모형인 KL-510에 해당하는 실제 트럭의 조합을 구성하였으며, 향후 공용중인 교량의 평가와 허가차량의 하중계수 보정에 적용할 수 있다.

• 한국정보과학회:학술대회논문집
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• 한국정보과학회 2007년도 가을 학술발표논문집 Vol.34 No.2 (B)
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• pp.22-27
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• 2007

Phosphorylation is one of the most important post translational modifications which regulate the activity of proteins. The problem of predicting phosphorylation sites is the first step of understanding various biological processes that initiate the actual function of proteins in each signaling pathway. Although many prediction methods using single or multiple features extracted from protein sequences have been proposed, systematic data integration approach has not been applied in order to improve the accuracy of predicting general phosphorylation sites. In this paper, we propose an optimal way of integrating multiple features in the framework of multiple kernel learning. We optimally combine seven kernels extracted from sequence, physico-chemical properties, pairwise alignment, and structural information. Using the data set of Phospho. ELM, the accuracy evaluated by 5-fold cross-validation reaches 85% for serine, 85% for threonine, and 81% for tyrosine. Our computational experiments show significant improvement in the performance of prediction relative to a single feature, or to the combined feature with equal weights. Moreover, our systematic integration method significantly improves the prediction preformance compared with the previous well-known methods.

• Journal of applied mathematics & informatics
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• 제4권2호
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• pp.501-512
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• 1997

In multiple linear regression model we have presupposed assumptions (independence normality variance homogeneity and so on) on error term. When case weights are given because of variance heterogeneity we can estimate efficiently regression parameter using weighted least squares estimator. Unfortunately this estimator is sen-sitive to outliers like ordinary least squares estimator. Thus in this paper we proposed some statistics for detection of outliers in weighted least squares regression.

• 한국전산구조공학회:학술대회논문집
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• 한국전산구조공학회 1999년도 봄 학술발표회 논문집
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• pp.102-109
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• 1999

Two phase simulated annealing algorithm is presented as a structural optimization technique and applied to minimum weight design of space trusses subjected to stress and displacement constraints under multiple loading conditions. Univariate searching algorithm is adopted for automatic selection of initial values of design variables for SA algorithm. The proper values of cooling factors and reasonable stopping criteria for optimum design of space truss structures are proposed to enhance the performance of optimization process. Optimum weights and design solutions are presented for two well-blown example structures and compared with those reported in the literature.

• 한국국방경영분석학회지
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• 제14권1호
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• pp.33-41
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• 1988

In Multiple Objective Linear Programming (MOLP), it is well known that efficient solution and weight are correspondent to each other. The purpose of this paper is to study relationships between efficient face and the region of weight in MOLP. It is shown that the regions of weights corresponding to two efficient extreme points are also neighbor if two efficient extreme points are neighbor each other, and that the set of the efficient solutions corresponding to the common part of weight regions is efficient face. Using the above, we present a method to find the efficient solutions corresponding to a given weight and vice versa.