• IMMUNE NETWORK
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• v.12 no.2
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• pp.41-47
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• 2012

Contemporary studies illustrate that peripheral injuries activate glial components of the peripheral and central cellular circuitry. The subsequent release of glial stressors or activating signals contributes to neuropathic pain and neuroinflammation. Recent studies document the importance of glia in the development and persistence of neuropathic pain and neuroinflammation as a connecting link, thereby focusing attention on the glial pathology as the general underlying factor in essentially all age-related neurodegenerative diseases. There is wide agreement that excessive glial activation is a key process in nervous system disorders involving the release of strong pro-inflammatory cytokines, which can trigger worsening of multiple disease states. This review will briefly discuss the recent findings that have shed light on the molecular and cellular mechanisms of glia as a connecting link between neuropathic pain and neuroinflammation.

• Korean Journal of Adult Nursing
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• v.18 no.3
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• pp.457-467
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• 2006

Purpose: The purpose of this study was to identify the main factors influencing family functioning of caregivers in families with stroke. Method: A Convenient sample of 173 primary family caregivers who take care of a stroke patient at an Oriental medicine hospital in Jeonbuk. Interviews were done with a standardized questionnaire including family functioning by nurses. Results: In Pearson's correlation analysis, the influencing factors related to family functioning were ADL(p=.017), level of paralysis(p=.019) as stressors, Quality of relation(p=.000) as situational variables, and family caregivers' burden(p=.000). Stepwise multiple regression analysis showed 29.9% of the variance family functioning was significantly accounted for by the quality of relationship between stroke patient and caregiver(26.8%), and caregiver burden(3.1%). Conclusions: Findings indicate that families of stroke patients need family-focused nursing intervention as supported care to improve the relationship between patient and primary caregiver and relieve caregiver burden by culturally tailoring to Korean.

• Molecules and Cells
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• v.47 no.1
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• pp.100006.1-100006.10
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• 2024

Nitric oxide (NO) serves as an evolutionarily conserved signaling molecule that plays an important role in a wide variety of cellular processes. Extensive studies in Drosophila melanogaster have revealed that NO signaling is required for development, physiology, and stress responses in many different types of cells. In neuronal cells, multiple NO signaling pathways appear to operate in different combinations to regulate learning and memory formation, synaptic transmission, selective synaptic connections, axon degeneration, and axon regrowth. During organ development, elevated NO signaling suppresses cell cycle progression, whereas downregulated NO leads to an increase in larval body size via modulation of hormone signaling. The most striking feature of the Drosophila NO synthase is that various stressors, such as neuropeptides, aberrant proteins, hypoxia, bacterial infection, and mechanical injury, can activate Drosophila NO synthase, initially regulating cellular physiology to enable cells to survive. However, under severe stress or pathophysiological conditions, high levels of NO promote regulated cell death and the development of neurodegenerative diseases. In this review, I highlight and discuss the current understanding of molecular mechanisms by which NO signaling regulates distinct cellular functions and behaviors.

• Journal of Korean Academy of Nursing
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• v.26 no.4
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• pp.808-819
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• 1996

The purpose of this study was to examine the stressors and coping strategies of school -age children and to explore the relationship between stressful life events and health symptoms and the effects of coping and trait anxiety which is theoretically considered to mediate the relationship between stress and health symptom. The study subjects consisted of 639 elementary school children in the fourth to sixth grade living in Seoul. Of the 639 subjects, 348 were boys and 291 were girls. The mean age was 11.35 (SD=.86). The Feel Bad Scale(FBS), Schoolager's Coping Strategy Inventory(SCSI), Spielberger's Trait Anxiety Scale for Children(STAIC), and Health Symptom Questionnaire (HSQ) were adapted for this study. A pilot study was undertaken to ascertain the reliability and validity of the instruments. The Cronbach alphas of FBS, SCSI, STAIC and HSQ were from .81 to .92. The Researcher and a research assistant visited the school and data were collected in the class using the questionnaire method after an explanation of the purpose and procedures was given to the children. Data collection was done during the period between Nov.25 to Dec.19, 1995. Using the SAS statistical program, percentages, t-test, ANOVA, correlation analysis, and multiple regression were used for data analysis. The result are as follows : 1. The mean score for the FBS was 204.79(range : 48-472) and there was a significant difference according to grade. The most severe stressors perceived by children were parental divorce and death or illness of family members. The most frequently experienced stressful life events were conflict with siblings and being home alone. 2. The mean score for the SCSI was 57.36(range : 9-118) and there was a significant difference according to grade. The most frequently used, and perceived as helpful, coping strategies were distraction and cognitive activities. 3. The mean score for the HSQ were 20.7(range : 0-81) and there were significant differences according to grade and sex. The percentage of the children answering that they perceived their health state as not good was 3.9%. 4. The mean score for the STAIC was 33.76 and there were significant differences according to grade and sex. 5. There was a significant relationship between stressful life events and health symptoms ( r=.53, p<.01). Also, Stressful life events were postively related with coping strategies(r=.39, p<.01). Trait anxiety was highly correlated with health symptoms(r=.72, p<.01). 6. To examine the multivariate effects of the variables to health symptoms, multiple regression was performed. Stressful life events, coping, trait anxiety, and health concerns were identified as significant variables. Explanation of the health symptoms by these variables was 56.78%. The study revealed that stressful life events correlated with health symptoms in school-age children and coping and trait anxiety had mediating effects on this relationship. The implication for nursing is that there is a need to develop supportive interventions for high risk population to decrease health problems due to stress. Also, it is recommended that a study be conducted to explore protective factors for the prevention of health problems in children.

• Child Health Nursing Research
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• v.4 no.2
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• pp.193-206
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• 1998

The purpose of this study was to examine the stressors and stress coping styles of 6th grade el ementary school children and to explore the relationship between stressful life events and health symptoms and the effects of coping style which is theoretically considered to mediate the relationship between stress and health symptoms. The study subjects consisted of 329 in 6th grade elementary school children in Cheong-Ju city. Of the 329 subjects, 171 were boys and 158 were girls. For this study, three kinds of questionnaires were adopted as follows ; 1) Feel Bad Scale (FBS) by Lewis et al., 2) lazarus-Folkman's Way of coping questionnaire 3) Hee Sun Shin's Health Symptom questionnaire (HSQ) The researcher visited the school and collected data in the class using the questionnaire method after an explanation of the purpose and procedures was given to the children. Data collection was done for 10 days (from 5th to 15th of July 1997) . The data were analyzed by descriptive statistics, correlation analysis, multiple regression analysis using the SAS statistical program. The results of this study were as follows : 1. The mean score for the FBS was 211.37(range : 77-427), The most severe stressors perceived by children were parental divorce and other's smash or steal of my things. The most frequently experienced stressful life events were conflict with siblings and being scolded for other's fault. 2. The most frequently used stress coping style was the active coping (M=17.85), followed by passive (M=13.64) and magical one (M=13.42). 3. The mean score for the HSQ was 23.30(range : 0-72) The most frequently complained health symptoms were headache and having much worry about everything. 4. There was a significant relationship between stressful life events and health symptoms (r=.60, p<.001). Also, stressful life events were positively related with passive coping(r=.27, p<.001) and magical coping (r=.38, p<.001). Health symptoms were positively correlated with passive coping(r=.33, p<.001) and magical coping (r=.41, p<.001). 5. Stepwise multiple regression analysis revealed that the most powerful predictor was the variable of stressful life events. Health concerns, magical coping style, passive coping style and active coping style accounted for 49.15% of the variance in health symptoms. This study revealed that stressful life events correlated with health symptoms in 6th grade elementary school children and passive coping and magical coping had mediating effects on this relationship. The implication for nursing is that there is a need to develop supportive interventions for high risk population to decrease health problems due to stress.

• Journal of dental hygiene science
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• v.7 no.2
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• pp.65-72
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• 2007

The purpose of this study was to examine the job stress and job stressors of dental hygienists. The subjects in the study were 220 dental hygienists who worked in north Jeolla province. After a mail survey was conducted from July 24 through September 24, 2006, the responses from 180 dental hygienists(response rate 81.8%) were gathered, and 156 answer sheets were analyzed except 24 incomplete ones that couldn't be analyzable. The findings of the study were as follows: 1. As for the correlation of overall job stress to turnover intention, their entire stress was under the influence of unreasonable treatment (r = 0.382), conflicts as a professional(r = 0.285), tough working environments(r = 0.303), conflicts with colleagues(r = 0.233), and heavy workload (r = 0.262). Those who were more stressed were more willing to change their occupation, and their stress level made a statistically significant difference to that(p < 0.01). 2. A multiple regression analysis was carried out by selecting the job stressors and turnover intention as independent and dependent variables respectively to see how each of the stressors affected job stress. And unreasonable treatment(p < 0.001) was identified as what had the biggest impact on that, followed by conflicts as a professional(p < 0.05), and tough working environments (p < 0.05). The stressors made a 22.2% prediction of turnover intention.

• Safety and Health at Work
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• v.6 no.2
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• pp.104-113
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• 2015

Background: Given the long hours on the road involving multiple and interacting work stressors (i.e., delivery pressures, irregular shifts, ergonomic hazards), commercial drivers face a plethora of health and safety risks. Researchers goal was to determine whether and to what extent long-haul trucker work schedules influence sleep duration and quality. Methods: Survey and biometric data collected from male long-haul truck drivers at a major truckstop in central North Carolina over a six month period. Results: Daily hours worked (mean = 11 hours, 55 minutes) and frequency of working over government-mandated daily HOS regulations (23.8% "frequently or always") were statistically significant predictors of sleep duration. Miles driven per week (mean = 2,812.61), irregular daily hours worked (63.8%), and frequency of working over the daily hour limit (23.8% "frequently or always") were statistically significant predictors of sleep quality. Conclusion: Implications of findings suggest a comprehensive review of the regulations and operational conditions for commercial motor vehicle drivers be undertaken.

• Journal of East-West Nursing Research
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• v.3 no.1
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• pp.68-82
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• 1998

This study attempted to develop fundamental data of nursing intervention for Women's health improvement through literature review related to women's health. Women's health problems are focused in nursing because the quality of women's health influences on public health directly and indirectly. Especially women experience more stressors and mental disorders than men. This paper reviewed rationale of mental problems to understand Women's mental problems through various research paper analysis. As a result, it was found that women's mental problems as well as the health were affected by various factors and were connected with social, cultural elements closely. This result means that women are affected by social, economical, psychological states from gender unequality in this society. So to solve the women's mental problems, women have to be considered as human beings, women, mothers with multiple roles. And like Hwabyung, one of the women's mental problems related to Korean traditional culture, nursing needs to be done to solve the problem through cultural approach. To do this, nursing has to research negative effect as well as positive effect on women's mental health by modern culture which includes "Han" and traditional family culture. The multidisplinary, interdisplinary communication is important to develop nursing intervention and nursing must build a pertinent Korean women's mental health research system to improve a sociopolitical environment.

• Journal of Families and Better Life
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• v.10 no.1 s.19
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• pp.115-130
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• 1992

The purpose of this study is ; 1) to identify the overall levels of family problem and stress perceived by urban homemakers, 2) to investigate the relations between them. For the purpose of this study, the samples were chosen among 369 homemakers living in Seoul. These data were analyzed by Frequency, mean, t-test, F-test, Duncan's Multiple Rang test and pearson's correlation. The significant results are as follows : 1) urban homemakers perceive 'economic problem' as the highest level, 'children problem' as the second one and 'health problem' as the lowest one in family life problem. There is significant difference in family problem perception according to education level, husband's job, children's numbers, and living level. 2) There is not sigificant difference in stress level according to independence variables. 3) There are positive correlations between the family problem perception and stress level of urban homemakers. In conclusion, we come to know every field of family life effects homemakers as stressors. According, it is necessary for us to understand and prevent family life problem in order to release stress perceived by homemakers.

• Journal of Fisheries and Marine Sciences Education
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• v.28 no.3
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• pp.667-677
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• 2016

Nursing students are exposed to a variety of stressors. The purpose of this study was to identify the factors influencing nursing students' college adjustment related to calling, work values and adaptation resources. The survey conducted in three nursing colleges (n=313) from 18th November to 30th December in 2015. The data were analyzed with descriptive statistics, independent t-tests, Pearson's correlation coefficient and multiple regression analyses using SPSS/Win 21 software. 41.9% of variance in college adjustment was accounted for by purpose/meaningfulness(t=6.871, p<.001), emotional stability(t=6.224, p<.001), altruism (t=2.708, p=.007), school year(4th)(t=3.073, p=.002), Hospitals in affiliation(t=2.822, p=.005), GPA(t=2.558, p=.011). The model was statistically significant explaining 41.9% of the variance(F=17.843, p<.001). This study suggests that a strategy increasing college adjustment for nursing students, is needed to consider purpose/meaningfulness, emotional stability, altruism.