• Title/Summary/Keyword: multiple resistance

Search Result 736, Processing Time 0.028 seconds

Variation-tolerant Non-volatile Ternary Content Addressable Memory with Magnetic Tunnel Junction

  • Cho, Dooho;Kim, Kyungmin;Yoo, Changsik
    • JSTS:Journal of Semiconductor Technology and Science
    • /
    • v.17 no.3
    • /
    • pp.458-464
    • /
    • 2017
  • A magnetic tunnel junction (MTJ) based ternary content addressable memory (TCAM) is proposed which provides non-volatility. A unit cell of the TCAM has two MTJ's and 4.875 transistors, which allows the realization of TCAM in a small area. The equivalent resistance of parallel connected multiple unit cells is compared with the equivalent resistance of parallel connected multiple reference resistance, which provides the averaging effect of the variations of device characteristics. This averaging effect renders the proposed TCAM to be variation-tolerant. Using 65-nm CMOS model parameters, the operation of the proposed TCAM has been evaluated including the Monte-Carlo simulated variations of the device characteristics, the supply voltage variation, and the temperature variation. With the tunneling magnetoresistance ratio (TMR) of 1.5 and all the variations being included, the error probability of the search operation is found to be smaller than 0.033-%.

Polymorphism in Intrinsic Antibiotic Resistance of Azospirillum Isolates from Ornamental Plants

  • Gadagi, Ravi;U., Krishnaraj P.;H., Kulkarni J.;Ahn, Ki-Sup;Sa, Tong-Min
    • Korean Journal of Environmental Agriculture
    • /
    • v.20 no.5
    • /
    • pp.330-334
    • /
    • 2001
  • The polymorphism of Azospirillum isolates from ornamental rhizosphere and two reference strains were examined with respect to intrinsic antibiotic resistance (IAR) profile. All the isolates showed different intrinsic resistances to different antibiotics viz., tetracycline, kanamycin, nalidixic acid, streptomycin, ampicillin, spectinomycin and chloramphenicol. All the strains demonstrated susceptibility to high concentration of all antibiotics used in the present experiment. In addition to these general patterns, we also obseved the multiple antibiotic resistances of Azospirillum strains. The Azospirillum sp. OAD-11 was resistant to tetracycline, streptomycin and ampicillin, and Azospirillum sp. OAD-57 was resistant to tetracycline and streptomycin. Conversely, Azospirillum sp. OAD-9 possessed the dual susceptibility to tetracycline and spectinomycin, whereas Azospirillum sp. OAD-37 was dual susceptible to streptomycin and kanamycin. Such multiple antibiotic resistant/susceptible traits could be useful for the identification of the strains in field experiments or in molecular genetic transfer experiments.

  • PDF

Antimicrobial Resistance Characteristics of Gram-Negative Bacteria Isolated from Inland Pollution Sources in the Drainage Basin of Iwon-myeon (Taean-gun), South Korea (태안군 이원면 육상오염원 배출수에서 분리한 그람음성균의 항생제 내성 특성)

  • Park, Bo Mi;Kim, Min Ju;Jeong, Yeon Gyeom;Park, Jin Il;Yu, Hong Sik;Oh, Eun Gyoung
    • Korean Journal of Fisheries and Aquatic Sciences
    • /
    • v.54 no.4
    • /
    • pp.377-387
    • /
    • 2021
  • Fecal contamination levels of discharge water from inland pollution sources were investigated in Iwon-myeon (Taean-gun), South Korea. Gram-negative bacteria were isolated during the investigation and the antimicrobial resistance patterns of the isolates were examined to estimate their impact on the coastal environment. The ranges of total coliform and fecal coliform of 12 samples from four major inland pollution sources were 79-490,000 MPN/100 mL and 2.0-490,000 MPN/100 mL, respectively, with the highest level of fecal contamination at Station No. 3. A total of 137 strains (14 genus) were isolated, of which 86 strains (62.8%) were Enterobacteriaceae. The identified isolates were as follows: Pseudomonas spp. (35 strains), Klebsiella spp. (20 strains), Serratia spp. (20 strains), and Escherichia spp. (19 strains). The isolated Gram-negative bacteria showed the highest antimicrobial resistance to ampicillin (81.8%), followed by amoxicillin/clavulanic acid (64.2%), ceftiofur (61.3%), and cefoxitin (59.1%). Antimicrobials in which less than 10% of isolates showed antimicrobial resistance were ciprofloxacin (3.6%) and gentamicin (2.2%). Resistance to one or more antimicrobials was observed in 121 strains (88.3%) and 84 strains (61.3%) showed a tendency for multiple antimicrobial resistance.

The 4-channel Multiple Contact Resistance Measurement Systems using MQTT Broker Server for AC 22.9 kV COS/Lightning Arrester (MQTT 브로커 서버를 이용한 AC 22.9 kV 차단기/피뢰기의 4-채널 다중 접촉저항 측정 시스템)

  • Ra-Yun Boo;Jung-Hun Choi;Myung-Eui Lee
    • Journal of Advanced Navigation Technology
    • /
    • v.27 no.2
    • /
    • pp.203-208
    • /
    • 2023
  • In this study, we propose a method to improve the precision of contact resistance measurement circuits using constant current method and voltage drop method, and implement a dashboard that monitors the measured data of contact resistance measurement systems through MQTT broker server. The contact resistance measurement system measures the resistance value and transmits the measured value to the MQTT broker server using wireless communications. This developed dashboard uses Node-RED and Node-RED-Dashboard to receive the resistance values of up to four contact resistance measurement systems and show them to user's monitor screen. Users can manage multiple measurement data using a single dashboard and easily interface with other devices through the MQTT broker server. Through the experimental results from real data measurements, the relative standard deviation about precision is improved to average 40.37% and maximum 64.73% respectively.

Mechanisms of herbicide resistance in weeds

  • Bo, Aung Bo;Won, Ok Jae;Sin, Hun Tak;Lee, Jeung Joo;Park, Kee Woong
    • Korean Journal of Agricultural Science
    • /
    • v.44 no.1
    • /
    • pp.1-15
    • /
    • 2017
  • In major field crops, synthetic herbicides have been used to control weeds worldwide. Globally, herbicide resistance in weeds should be minimized because it is a major limiting factor for food security. Cross resistance can occur with herbicides within the same or in different herbicide families and with the same or different sites of action. Multiple resistance refers to evolved mechanisms of resistance to more than one herbicide (e.g., resistance to both ALS-inhibitors and ACCase-inhibitors) and this resistance was brought about by separate selection processes. Target site resistance could occur from changes at the biochemical site of action of one herbicide. Non target site resistance occurs through mechanisms which reduce the number of herbicide molecules that reach the herbicide target site. There are currently 480 unique cases (species ${\times}$ site of action) of herbicide resistance globally in 252 plant species (145 dicots and 105 monocots). To date, resistance in weeds has been reported to 161 different herbicides, involving 23 of the 26 known herbicide sites of action. Finally, it can be concluded that we can protect crops associated to herbicide resistant weeds by applications of biochemical, genetic and crop control strategies.

The Determinants of Innovation Resistance and Innovation Performances (혁신저항의 결정요인과 혁신성과에 대한 실증적 연구)

  • Ahn, Byeong Deok;Ahn, Kwan Young
    • Journal of the Korea Safety Management & Science
    • /
    • v.16 no.1
    • /
    • pp.191-199
    • /
    • 2014
  • This paper reviewed the relationship among CEO's entrepreneurship/risktaking, innovation resistance and innovation performance, and the mediating effect of innovation resistance between CEO's entrepreneurship/risktaking and innovation performance. Based on the responses from 219 companies, the results of multiple regression analysis appeared as follow; 1) CEO's entrepreneurship and risktaking effect negatively on innovation resistance. 2) innovation resistance negatively on innovation performance(process innovation, organization innovation). 3) innovation resistance mediates partly between CEO's entrepreneurship/risktaking and innovation performance.

Performance and modeling of high-performance steel fiber reinforced concrete under impact loads

  • Perumal, Ramadoss
    • Computers and Concrete
    • /
    • v.13 no.2
    • /
    • pp.255-270
    • /
    • 2014
  • Impact performance of high-performance concrete (HPC) and SFRC at 28-day and 56-day under the action of repeated dynamic loading was studied. Silica fume replacement at 10% and 15% by mass and crimped steel fiber ($V_f$ = 0.5%- 1.5%) with aspect ratios of 80 and 53 were used in the concrete mixes. Results indicated that addition of fibers in HPC can effectively restrain the initiation and propagation of cracks under stress, and enhance the impact strengths and toughness of HPC. Variation of fiber aspect ratio has minor effect on improvement in impact strength. Based on the experimental data, failure resistance prediction models were developed with correlation coefficient (R) = 0.96 and the estimated absolute variation is 1.82% and on validation, the integral absolute error (IAE) determined is 10.49%. On analyzing the data collected, linear relationship for the prediction of failure resistance with R= 0.99 was obtained. IAE value of 10.26% for the model indicates better the reliability of model. Multiple linear regression model was developed to predict the ultimate failure resistance with multiple R= 0.96 and absolute variation obtained is 4.9%.

Isolation, Molecular Characterization and Antibiotic Susceptibility Pattern of Vibrio parahaemolyticus from Aquatic Products in the Southern Fujian Coast, China

  • Hu, Yuanqing;Li, Fengxia;Zheng, Yixian;Jiao, Xinan;Guo, Liqing
    • Journal of Microbiology and Biotechnology
    • /
    • v.30 no.6
    • /
    • pp.856-867
    • /
    • 2020
  • Vibrio parahaemolyticus is a major gastroenteritis-causing pathogen in many Asian countries. Antimicrobial resistance in V. parahaemolyticus has been recognized as a critical threat to food safety. In this study, we determined the prevalence and incidence of antimicrobial resistance in V. parahaemolyticus in the southern Fujian coast, China. A total of 62 isolates were confirmed in retail aquatic products from June to October of 2018. The serotype O3:K6 strains, the virulence genes tdh and trh, antibiotic susceptibility and molecular typing were investigated. Then plasmid profiling analysis and curing experiment were performed for multidrug-resistant strains. The results showed that the total occurrence of V. parahaemolyticus was 31% out of 200 samples. Five strains (8.1%) out of 62 isolates were identified as the V. parahaemolyticus O3:K6 pandemic clone. A large majority of isolates exhibited higher resistance to penicillin (77.4%), oxacillin (71%), ampicillin (66.1%) and vancomycin (59.7%). Seventy-one percent (44/62) of the isolates exhibited multiple antimicrobial resistance. All 62 isolates were grouped into 7 clusters by randomly amplified polymorphic DNA, and most of the isolates (80.6%) were distributed within cluster A. Plasmids were detected in approximately 75% of the isolates, and seven different profiles were observed. Seventy-six percent (25/33) of the isolates carrying the plasmids were eliminated by 0.006% SDS incubated at 42℃, a sublethal condition. The occurrence of multidrug-resistant strains could be an indication of the excessive use of antibiotics in aquaculture farming. The rational use of antimicrobial agents and the surveillance of antibiotic administration may reduce the acquisition of resistance by microorganisms in aquatic ecosystems.

Food-borne outbreaks, distributions, virulence, and antibiotic resistance profiles of Vibrio parahaemolyticus in Korea from 2003 to 2016: a review

  • Park, Kunbawui;Mok, Jong Soo;Kwon, Ji Young;Ryu, A Ra;Kim, Song Hee;Lee, Hee Jung
    • Fisheries and Aquatic Sciences
    • /
    • v.21 no.2
    • /
    • pp.3.1-3.10
    • /
    • 2018
  • Background: Vibrio parahaemolyticus is one of the most common causes of seafood-borne illnesses in Korea, either directly or indirectly, by consuming infected seafood. Many studies have demonstrated the antibiotic susceptibility profile of V. parahaemolyticus. This strain has developed multiple antibiotic resistance, which has raised serious public health and economic concerns. This article reviews the food-borne outbreaks, distributions, virulence, and antibiotic resistance profiles of V. parahaemolyticus in Korea during 2003-2016. Main body: V. parahaemolyticus infections appeared to be seasonally dependent, because 69.7% of patient infections occurred in both August and September during 2003-2016. In addition, the occurrence of V. parahaemolyticus in marine environments varies seasonally but is particularly high in July, August, and September. V. parahaemolyticus isolated from aquaculture sources on the Korean coast varied in association with virulence genes, some did not possess either the tdh (thermostable direct hemolysin) or trh (tdh-related hemolysin) genes, and a few were positive for only the trh gene or both genes. The high percentage of ampicillin resistance against V. parahaemolyticus in the aquatic environment suggests that ampicillin cannot be used to effectively treat infections caused by this organism. Short conclusion: This study shows that the observed high percentage of multiple antibiotic resistance to V. parahaemolyticus is due to conventionally used antibiotics. Therefore, monitoring the antimicrobial resistance patterns at a national level and other solutions are needed to control aquaculture infections, ensure seafood safety, and avoid threats to public health caused by massive misuse of antibiotics.

The Effects of Long-Term, Low-Level Exposure to Monocyclic Aromatic Hydrocarbons on Worker's Insulin Resistance

  • Won, Yong-Lim;Ko, Yong;Heo, Kyung-Hwa;Ko, Kyung-Sun;Lee, Mi-Young;Kim, Ki-Woong
    • Safety and Health at Work
    • /
    • v.2 no.4
    • /
    • pp.365-374
    • /
    • 2011
  • Objectives: This study was designed to investigate whether long-term, low-level exposure to monocyclic aromatic hydrocarbons (MAHs) induced insulin resistance. Methods: The subjects were 110 male workers who were occupationally exposed to styrene, toluene, and xylene. One hundred and ten age-matched male workers who had never been occupationally exposed to organic solvents were selected as a control group. Cytokines, which have played a key role in the pathogenesis of insulin resistance, and oxidative stress indices were measured. Assessment of exposure to MAHs was performed by measuring their ambient levels and their urinary metabolites in exposed workers, and the resulting parameters between the exposed group and non-exposed control groups were compared. Results: There was no significant difference in general characteristics and anthropometric parameters between the two groups; however, total cholesterol, fasting glucose, fasting insulin, and homeostasis model assessment of insulin resistance levels were significantly higher in the exposed group. Phenylglyoxylic acid levels showed significant association with tumor necrosis factor-${\alpha}$, total oxidative status, and oxidative stress index via multiple linear regression analysis. Further, there was a negative correlation between methylhippuric acid levels and total anti-oxidative capacity, and there was a significant relationship between MAHs exposure and fasting glucose levels, as found by multiple logistic regression analysis (odds ratio = 3.95, 95% confidence interval = 1.074-14.530). Conclusion: This study indicated that MAHs increase fasting glucose level and insulin resistance. Furthermore, these results suggested that absorbing the organic solvent itself and active metabolic intermediates can increase oxidative stress and cytokine levels, resulting in the changes in glucose metabolism and the induction of insulin resistance.