• Journal of Microbiology and Biotechnology
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• 제29권6호
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• pp.962-972
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• 2019

Non-typhoidal Salmonella (NTS) is one of the most frequent causes of bacterial foodborne illnesses. Considering that the main reservoir of NTS is the intestinal tract of livestock, foods of animal origin are regarded as the main vehicles of Salmonella infection. In particular, poultry colonized with Salmonella Typhimurium (S. Typhimurium), a dominant serotype responsible for human infections, do not exhibit overt signs and symptoms, thereby posing a potential health risk to humans. In this study, comparative genomics approaches were applied to two S. Typhimurium strains, ST1539 and ST1120, isolated from a duck slaughterhouse and a pig farm, respectively, to characterize their virulence and antimicrobial resistance-associated genomic determinants. ST1539 containing a chromosome (4,905,039 bp; 4,403 CDSs) and a plasmid (93,876 bp; 96 CDSs) was phylogenetically distinct from other S. Typhimurium strains such as ST1120 and LT2. Compared to the ST1120 genome (previously deposited in GenBank; CP021909.1 and CP021910.1), ST1539 possesses more virulence determinants, including ST64B prophage, plasmid spv operon encoding virulence factors, genes encoding SseJ effector, Rck invasin, and biofilm-forming factors (bcf operon and pefAB). In accordance with the in silico prediction, ST1539 exhibited higher cytotoxicity against epithelial cells, better survival inside macrophage cells, and faster mice-killing activity than ST1120. However, ST1539 showed less resistance against antibiotics than ST1120, which may be attributed to the multiple resistanceassociated genes in the ST1120 chromosome. The accumulation of comparative genomics data on S. Typhimurium isolates from livestock would enrich our understanding of strategies Salmonella employs to adapt to diverse host animals.

• 천문학회보
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• 제44권1호
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• pp.37.2-37.2
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• 2019

Recent investigations of the double red clump in the color-magnitude diagram of the Milky Way bulge cast serious doubts on the structure and formation origin of the outer bulge. Unlike previous interpretation based on an X-shaped bulge, stellar evolution models and CN-band observations have suggested that this feature is another manifestation of the multiple stellar population phenomenon observed in globular clusters (GCs). This new scenario requires a significant fraction of the outer bulge stars with chemical patterns uniquely observed in GCs. Here we show from homogeneous high-quality spectroscopic data that the red giant branch stars in the outer bulge ($>5.5^{\circ}$ from the Galactic center) are clearly divided into two groups according to Na abundance in the [Na/Fe] - [Fe/H] plane. The Na-rich stars are also enhanced in Al, while the differences in O and Mg are not observed between the two Na groups. The population ratio and the Na and Al differences between the two groups are also comparable with those observed in metal-rich GCs. Since these chemical patterns and characteristics are only explained by stars originated in GCs, this is compelling evidence that the outer bulge was mostly assembled from disrupted proto-GCs in the early history of the Milky Way. We will also discuss the implications of this result on the formation of the early-type galaxies in general.

• 한국학교보건학회지
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• 제33권3호
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• pp.164-174
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• 2020

Purpose: The purpose of this study was to identify the factors affecting tuberculosis prevention behaviors in North Korean adolescent refugees. Methods: From September 16 to October 8, 2019, a survey was conducted to collect data from 143 North Korean adolescent refugees aged 13 to <25 at alternative and general schools in Seoul and Gyeonggi Province. The scale developed by Park (2008) and adapted by Cha (2012) was used to rate tuberculosis prevention behaviors in daily life with the aim of preventing high school students from getting infected with tuberculosis. The collected data were processed through frequency analysis, descriptive statistics, t-test, ANOVA, Pearson's correlation coefficients, and multiple linear regression, using SPSS 25.0. Results: The mean score was 13.65 for knowledge of tuberculosis, 44.23 for attitudes towards tuberculosis, and 41.33 for tuberculosis prevention behaviors. Significant differences were found according to gender, country of origin, duration of stay in South Korea, tuberculosis examination, pre-entry chest x-ray, education about tuberculosis, alcohol intake, and subjective health status. A positive correlation was found between knowledge, attitudes, and prevention behaviors. The factors affecting tuberculosis prevention behaviors were attitudes (β=.38, p<001) and subjective health status (β=.26, p<.001). Conclusion: It is necessary to provide attitude-based education that can reinforce positive attitudes in order to improve North Korean adolescent refugees' tuberculosis prevention behaviors. This is expected to help them pay more attention to health care and become better at prevention behaviors. It is, therefore, necessary to develop a tuberculosis prevention education program with the aim of making them more knowledgeable about tuberculosis and providing them with systematic and sustainable education.

• 정보보호학회논문지
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• 제7권2호
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• pp.55-72
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• 1997

본 논문에서는 FAX문서에 직접 서명을 실행하는 디지털 서명 방식을 제안한다. 서명 비트를 합성하기 위해 기주사된 복수개의 참조 주사선중 키에 의해 선택된 주사선의 변화화소와 부호화주사선의 변화화소의 거리의 우기성을 이용하여 합성 비트열에 따라 거리를 신축조작하는 합성알고리즘을 제안한다. 앞서 제시한 방식에 비해 서명의 확산이 가능하므로 부분 서명에 의해 문서전체에 대한 서명이 구현되어 서명 속도가 개선되며 합성 전제조건의 제거로 합성 가능량이 증가한다. 또한 제안하는 디지털 서명구조에 의해 디지털 서명의 제 3 조건인 송신 부인 봉쇄를 구현한다. 디지털 서명된 송신 문서는 원 문서와 시각적으로 구분이 어려워 제 3자에게는 통상의 문서교환으로 인식될 것이다.

• 한국콘텐츠학회논문지
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• 제21권5호
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• pp.776-793
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• 2021

본 연구는 다문화 청소년이 학교에서 경험하는 차별에 대해 심층적으로 이해하고자 질적 연구를 수행하였다. 이를 위해 국내출생 다문화 청소년 12명을 대상으로 심층면담을 실시하고 Giorgi의 현상학적 방법으로 분석하였다. 수집한 자료를 분석한 결과, 58개의 중심의미와 22개의 드러난 주제, 9개의 본질적 주제를 도출하였다. 본질적 주제는 '원치 않는 다문화 알려짐과 부정적 감정의 경험', '다문화가 나라는 존재를 결정하게 됨', '다문화라는 사실로부터 영향을 받지 않음', '다문화에 대한 호의적 반응과 도움의 경험', '내가 어떻게 할 수 없는 것들이 차별의 이유가 됨', '흥밋거리나 함부로 다루어지는 존재가 됨', '다문화 교육과 주변의 관심이 도움이 되지 않음', '자신의 힘으로는 멈출 수 없는 차별과 해결되지 않는 차별의 영향', '다문화 청소년으로서 가지게 되는 자기인식'으로 나타났다. 연구 결과를 바탕으로 향후 연구 제언 및 시사점을 논의에 제시하였다.

• 한국전기전자재료학회논문지
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• 제35권6호
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• pp.523-546
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• 2022

Morphotropic phase boundary (MPB), which is a special boundary that separates two or multiple different phases in the phase diagram of some ferroelectric ceramics, is an important concept in identifying physics that includes piezoelectric responses. MPB, which had not been discovered in organic materials until recently, was discovered in poly(vinylidene fluoride-co-trifluoroethylene (P(VDF-TrFE)), resulting from a molecular approach. The piezoelectric coefficient of P(VDF-TrFE) in this MPB region was achieved up to -63.5 pC N^-1, which is about two times as large as the conventional value of -30 pC N^-1 of P(VDF-TrFE). An order-disorder arrangement greatly affects the rise of the piezoelectric effect and the ferroelectric, paraelectric and relaxor ferroelectric of P(VDF-TrFE), so the arrangement and shape of the polymer chain is important. In this review, we investigate the origin of negative longitudinal piezoelectric coefficients of piezoelectric polymers, which is definitely opposite to those of common piezoelectric ceramics. In addition to the mainly discussed issue about MPB behaviors of ferroelectric polymers, we also introduce the consideration about polymer chirality resulting in relaxor ferroelectric properties. When the physics of ferroelectric polymers is unveiled, we can improve the piezoelectric and pyroelectric properties of ferroelectric polymers and contribute to the development of next-generation sensor, energy, transducer and actuator applications.

• 한국식물병리학회:학술대회논문집
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• 한국식물병리학회 2003년도 정기총회 및 추계학술발표회
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• pp.141.1-141
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• 2003

Forty six isolates of bean common mosaic virus (BCMV) collected from azuki bean, mungbean, kidney bean, cowpea, broad bean and peanut were classified into three groups based on biological, serological, cytopathological, and molecular characteristics. Group I induced vein-banding symptoms in cowpea which was similar to those produced by the BCMV-cowpea strain. Group II caused mosaic symptoms in azuki bean but not in peanut and tobacco. Since this character was different from that of previously described BCMV strain, group II may not belong to BCMV GroupIII induced vein-clearing symptoms in azuki bean, kidney bean and peanut, which are typical symptoms for BCMV-peanut stripe virus strain. Virus inclusion patterns of BCMV groups were similar to those of Potyvirus subdivision III with the scroll, pinwheel and long laminated inclusions. However, the inclusions of laminated aggregates were never observed in mungbean isolates. Multiple alignment as well as cluster dendrograms of 3'noncoding region (3'-NCR) and a part of coat protein gene (CP) suggested that group I belongs to the BCMV-cowpea strain, group II to the BCMV-azuki bean strain, and group III to the BCMV-peanut stripe virus strain. Since molecular phylogenesis of BCMV based on nucleotides of 3'-NCR and coat protein differed from the grouping based on virulence differentiation, and BCMV groups are more closely related to each other with the same host origin, other characteristics of those strains are under investigation.

• 지적과 국토정보
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• 제53권1호
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• pp.21-36
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• 2023

전 세계적으로 가장 널리 사용되고 있는 교통수요모형은 전통적 4단계 교통수요모델이다. 하지만, 기존 분석방법은 시공간적으로 다양한 분석에 제약을 가지고 있으며, 이러한 한계를 극복하기 위해 최근 활동기반 모형 및 시스템이 활발히 연구 개발되고 있다. 이에 본 연구에서는 빅데이터를 활용한 활동기반 통행자분석시스템 ABATA(Activity-Based Traveler Analyzer) 기술개발을 소개한다. 이 시스템은 시간별 총인구 추정, 활동 프로파일 생성, 시간별 활동 인구 추정, 공간 활동 인구 추정 및 출발지·목적지 추정 등의 구성요소를 포함한다. 제안된 시스템을 실증하기 위해 사례연구로 세종시 5-1 블록스마트시티를 대상으로 토지이용변화에 따른 배기가스 배출영향을 평가하였다. 그 결과 업무시설 분산계획 시나리오의 토지이용이 업무시설 집중계획 시나리오보다 이동 거리가 길어 배출량이 더 많이 발생하는 것으로 나타났다. 제안된 ABATA 시스템은 활동 인구 및 통행 수요에 대한 인구, 활동 일정 및 미래 토지이용의 변화 영향을 시뮬레이션하기 위한 유용한 도구를 제공할 것으로 기대된다.

• Journal of Yeungnam Medical Science
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• 제40권4호
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• pp.448-453
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• 2023

Takayasu arteritis (TA) is a disease that causes inflammation and stenosis of medium to large blood vessels. We report a case of a 50-year-old female patient with newly developed hypertension, syncope, and claudication of the extremities. Total occlusion of the left subclavian artery at the origin was found and significant stenosis of the right common iliac artery was revealed by hemodynamic analysis. She was successfully treated with percutaneous angioplasty for multiple peripheral arterial diseases and was finally diagnosed with TA. In consultation with a rheumatologist, medical treatment for TA was initiated, the patient's hypertension disappeared, and her claudication symptoms improved.

• Clinical and Experimental Pediatrics
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• 제48권3호
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• pp.321-326
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• 2005

가와사끼병은 주로 소아연령에서 발생하는 급성 열성 혈관염으로 관상동맥의 확장이 치명적 합병증으로 나타날 수 있다. 저자들은 3개월된 영아에서 반복적인 정맥용 면역글로불린, 스테로이드, 경구용 methotrexate의 치료에도 불구하고 진행되는 관상동맥 병변으로 다발성 거대 관상류, 협착 및 관상동맥 내 혈전을 보이며 심전도상 심근 허혈 소견과 함께 심장 자기공명영상에서 좌심실의 확장과 전벽 및 중격의 심한 운동저하를 나타낸 증례를 보고한다. 환아는 보존적 요법에 반응하지 않는 관상동맥병변으로 내원 88일째 수술적으로 우측 거대관상동맥류를 절개하고 Gore-tex tube를 삽입하여 각각의 측부순환과 연결하였으며, 좌측 관상동맥 협착부위는 세로로 절개한 후 심장막 반(pericardial patch)을 삽입, 확장하였으나, 수술 후 심폐부전으로 사망하였다.