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A Case of Multiple Giant Coronary Aneurysms with Large Mural Thrombus due to Kawasaki Disease in a Young Infant  

Choi, Eun Na (Department of Pediatrics, Cardiovascular Center, Yonsei University College of Medicine)
Kim, Jeoung Tae (Department of Pediatrics, Cardiovascular Center, Yonsei University College of Medicine)
Kim, Yuria (Department of Pediatrics, Cardiovascular Center, Yonsei University College of Medicine)
Yoo, Byung Won (Department of Pediatrics, Cardiovascular Center, Yonsei University College of Medicine)
Choi, Deok Young (Department of Pediatrics, Cardiovascular Center, Yonsei University College of Medicine)
Choi, Jae Young (Department of Pediatrics, Cardiovascular Center, Yonsei University College of Medicine)
Sul, Jun Hee (Department of Pediatrics, Cardiovascular Center, Yonsei University College of Medicine)
Lee, Sung Kye (Department of Pediatrics, Cardiovascular Center, Yonsei University College of Medicine)
Kim, Dong Soo (Department of Pediatrics, Cardiovascular Center, Yonsei University College of Medicine)
Park, Young Hwan (Department of Cardiovascular Surgery, Cardiovascular Center, Yonsei University College of Medicine)
Publication Information
Clinical and Experimental Pediatrics / v.48, no.3, 2005 , pp. 321-326 More about this Journal
Abstract
Kawasaki disease is an acute systemic vasculitis of unknown origin. Giant coronary aneurysm is one of the most serious complications, although peripheral artery vasculitis can produce life-threatening events. Myocardial ischemia and infarction can be caused by coronary artery stenosis, aneurysm, and stagnation of blood flow in coronary arteries which triggers thromboembolism. Atypical presentation in young infants often interferes with prompt diagnosis and timely treatment, resulting in poor outcomes. We describe a 3-month-old infant with multiple giant coronary aneurysms with flow stagnation, stenosis and large mural thrombus due to Kawasaki disease. He presented with a prolonged course of severe coronary involvement in spite of all measures to reduce coronary complications. Finally, surgical intervention was tried because of the worsening coronary artery abnormalities. The patient died of acute cardiorespiratory failure shortly after weaning from cardiopulmonary bypass.
Keywords
Mucocutaneous lymph node syndrome; Coronary aneurysm; Coronary thrombosis; Infant; Myocardial ischemia;
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