• Title/Summary/Keyword: multiple corresponding analysis

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Development of Eyes Inspection Questionnaire(EIQ) and Regression Analysis between EIQ Items and deficiency or excess patterns of Eyes Inspection (안진(眼診) 설문지 개발 및 안진(眼診) 설문의 허실(虛實) 연관성 연구)

  • Seo, Jae-Ho;Choi, Jin-Yong;Oh, Whan-Sup;Park, Young-Bae;Park, Young-Jae
    • The Journal of the Society of Korean Medicine Diagnostics
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    • v.18 no.2
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    • pp.75-84
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    • 2014
  • Objectives Eyes, one of visual inspection regions, present important clues to pathological patterns including deficiency and excess patterns to the clinicians. The purpose of this study was to develop Eyes Inspection Questionnaire (EIQ) and to examine which items among the EIQ were more predictive of clinicians' determination for the deficiency and excess patterns. Methods Nine questionnaire items for Visual Inspection of Eyes were extracted through the literature review. These items were presented to the 4 Korean medical doctors who are specialized in visual inspection to conduct the Delphi method. The Korean medical doctors were asked to rate the importance of each items for the corresponding Visual Inspection of Eyes, using a Likert 5-point scale(the 3 points of importance as a cut-off point). Then, out of 75 photographs submitted to the Society of HyungSang Medicine in 2009, 30 portrait pictures were selected as samples. The samples were copied to make 60 sample pictures, and then randomly assigned to 4 clinicians. The 4 clinicians evaluated the 60 samples for excess and deficiency of the eyes and were asked to check the 6 questionnaire items. The results were recorded as 5-points-scale, and their average and standard deviations were calculated. Intra- class reliability test and multi regression test were performed using SPSS 13. Results Intra-class correlation coefficient (ICC) was between 0.750 to 0.841 (P<0.05). Indices for visual inspection of the eyes were: endowment of the bone structure around the eyes; brightness of the eyes; upward deviation of the eyes; eye shapes; and definition of iris. 76.92% of deficiency symptom patterns and 86.42% of the excess symptom patterns matched the patterns predicted by the visual inspection of the eyes, according to the frequency analysis. According to the multiple regression analysis, were significantly related to the excessive symptoms, and to the deficiency symptoms. Conclusion This study is the first attempt of development for checklist of excess and deficiency of Visual Inspection of Eyes and quantitative measurement of excess and deficiency using the Visual Inspection of Eyes by the visual inspection experts. Still, additional studies are needed regarding the relationship visual inspection methods have with existing standards of diagnosis.

Blood Pressure and Dietary Related Risk Factors Associated with High Sodium Intake Assessed with 24-hour Urine Analysis for Korean Adults (한국 성인들의 24시간 소변 분석법에 근거한 고나트륨군의 혈압과 고나트륨 섭취관련 위험인자에 관한 연구)

  • Jeong, Yeon-Seon;Lim, Hwa-Jae;Kim, Sook-Bae;Kim, Hee Jun;Son, Sook Mee
    • Korean Journal of Community Nutrition
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    • v.19 no.6
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    • pp.537-549
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    • 2014
  • Objectives: This study was conducted to examine blood pressure and other characteristics of a high sodium intake group assessed with 24-hr urine analysis and the dietary factors related to the risk of high sodium intake among Korean adults. Methods: A cross-sectional study was conducted with adults aged 20-59 years. Subjects who completed 24-hr urine collection (N = 205) were divided into 3 groups (tertile) according to the sodium intake estimated with 24-hour urine analysis. We compared the blood pressure, BMI and dietary related factors of the 3 groups (low, medium, high sodium intake group) with General Linear Model (GLM) and Duncan's multiple range test (p < 0.05). The risk factors related to high sodium intake were assessed with odds ratio (p < 0.05). Results: The sodium intake (mg/day) of the 3 groups were $3359.8{\pm}627.9$, $4900.3{\pm}395.1$ and $6770.6{\pm}873.9$, respectively, corresponding to daily salt intake (g/day) 8.5, 12.4 and 17.2, respectively. High sodium group showed significantly elevated age, BMI and systolic/diastolic blood pressure. Being male gender was associated with significantly increased risk of sodium intake (OR = 1.972; 95%CI: 1.083-3.593). The other factors related to high sodium intake were higher BMI (${\leq}25$) (OR = 2.619; 95% CI: 1.368-5.015), current alcohol consumption (OR = 1.943; 95%CI: 1.060-3.564), and having salty soybean paste with salt percentage > 14% (OR = 3.99; 95% CI: 1.404-6.841). The dietary attitude related to increased risk of high sodium intake included 'enjoy dried fish and salted mackerel' (p < 0.001) and 'eat all broth of soup, stew or noodle' (p < 0.001). Conclusions: Because high sodium intake was associated with higher blood pressure, nutrition education should focus on alcohol consumption, emphasis on related dietary factors such as using low salt soybean paste, improvements in the habit of eating dried fish and salted mackerel or eating all broth of soup, stew or noodle.

An Estimation of Flood Quantiles at Ungauged Locations by Index Flood Frequency Curves (지표홍수 빈도곡선의 개발에 의한 미 계측지점의 확률 홍수량 추정)

  • Yoon, Yong-Nam;Shin, Chang-Kun;Jang, Su-Hyung
    • Journal of Korea Water Resources Association
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    • v.38 no.1
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    • pp.1-9
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    • 2005
  • The study shows the possible use of the index flood frequency curves for an estimation of flood quantiles at ungauged locations. Flood frequency analysis were made for the annual maximum flood data series at 9 available stations in the Han river basin. From the flood frquency curve at each station the mean annual flood of 2.33-year return period was determined and the ratios of the flood magnitude of various return period to the mean annual flood at each station were averaged throughout the Han river basin, resulting mean flood ratios of different return periods. A correlation analysis was made between the mean annual flood and physiographic parameters of the watersheds i.e, the watershed area and mean river channel slope, resulting an empirical multiple linear regression equation over the whole Han river basin. For unguaged watershed the flood of a specified return period could be estimated by multiplying the mead flood ratio corresponding the return period with the mean annual flood computed by the empirical formula developed in terms of the watershed area and river channel slope. To verify the applicability of the methodology developed in the present study the floods of various return periods determined for the watershed in the river channel improvement plan formulation by the Ministry of Construction and Transportation(MOCT) were compared with those estimated by the present method. The result proved a resonable agreement up to the watershed area of approximately 2,000k $m^2$. It is suggested that the practice of design flood estimation based on the rainfall-runoff analysis might have to be reevaluated because it involves too much uncertainties in the hydrologic data and rainfall-runoff model calibration.

Long-term sequelae of trajectories of bullying victimization in youth: Internalizing and externalizing behavioral outcomes (또래 괴롭힘 피해경험 발달유형에 따른 내면화 및 외현화 문제 양상)

  • Park, Hyun-Sun;Kim, Min Jung;Chung, Ick-Joong
    • Korean Journal of Social Welfare Studies
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    • v.45 no.2
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    • pp.5-30
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    • 2014
  • This study sought to identify developmental trajectories of bullying victimization from late elementary school through early high school, and to examine internalizing and externalizing problem outcomes associated with the trajectory group membership. Data from Seoul Panel Study of Children were collected annually over a 7-year period from 5th grade of elementary school through 2nd grade of high school (2005~2011). Latent class growth analysis yield three trajectory classes corresponding to stable low (81.2%), stable high (3.5%), and declining bullying victimization (15.6%). Findings from analysis of covariance indicated that students in both stable high and declining trajectory groups reported significantly higher means in internalizing behavior (withdrawal, depression/anxiety, and suicide ideation), compared to those in the stable low group. For externalizing behavior such as aggression and juvenile status offense, students in the stable high group showed higher means, compared to those in the stable low and declining trajectory groups. Developmental pattern of bullying victimization over multiple development stages and associated internalizing and externalizing outcomes are discussed as are the implications for the bullying prevention.

Machine Learning for Predicting Entrepreneurial Innovativeness (기계학습을 이용한 기업가적 혁신성 예측 모델에 관한 연구)

  • Chung, Doo Hee;Yun, Jin Seop;Yang, Sung Min
    • Asia-Pacific Journal of Business Venturing and Entrepreneurship
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    • v.16 no.3
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    • pp.73-86
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    • 2021
  • The primary purpose of this paper is to explore the advanced models that predict entrepreneurial innovativeness most accurately. For the first time in the field of entrepreneurship research, it presents a model that predicts entrepreneurial innovativeness based on machine learning corresponding to data scientific approaches. It uses 22,099 the Global Entrepreneurship Monitor (GEM) data from 62 countries to build predictive models. Based on the data set consisting of 27 explanatory variables, it builds predictive models that are traditional statistical methods such as multiple regression analysis and machine learning models such as regression tree, random forest, XG boost, and artificial neural networks. Then, it compares the performance of each model. It uses indicators such as root mean square error (RMSE), mean analysis error (MAE) and correlation to evaluate the performance of the model. The analysis of result is that all five machine learning models perform better than traditional methods, while the best predictive performance model was XG boost. In predicting it through XG boost, the variables with high contribution are entrepreneurial opportunities and cross-term variables of market expansion, which indicates that the type of entrepreneur who wants to acquire opportunities in new markets exhibits high innovativeness.

A Profit Prediction Model in the International Construction Market - focusing on Small and Medium Sized Construction Companies (CBR을 활용한 해외건설 수익성 예측 모델 개발 - 중소·중견기업을 중심으로 -)

  • Hwang, Geon Wook;Jang, woosik;Park, Chan-Young;Han, Seung-Heon;Kim, Jong Sung
    • Korean Journal of Construction Engineering and Management
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    • v.16 no.4
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    • pp.50-59
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    • 2015
  • While the international construction industry for Korean companies have grown in market size exponentially in the recent years, the profit rate of small and medium sized construction companies (SMCCs) are incomparably lower than those of large construction companies. Furthermore, small and medium size companies, especially subcontractor, lacks the judgement of project involvement appropriateness, which leads to an unpredictable profit rate. Therefore, this research aims to create a profit rate prediction model for the international construction project focusing on SMCCs. First, the factors that influence the profit rate and the area of profit zone are defined by using a total of 8,637 projects since the year 1965. Seconds, an extensive literature review is conducted to derive 10 influencing factors. Multiple regression analysis and corresponding judgement technique are used to derive the weight of each factor. Third, cased based reasoning (CBR) methodology is applied to develop the model for profit rate analysis in the project participation review stage. Using 120 validation data set, the developed model showed 11% (14 data sets) of error rate for type 1 and type 2 error. In utilizing the result, project decision makers are able to make decision based on authentic results instead of intuitive based decisions. The model additionally give guidance to the Korean subcontractors when advancing into the international construction based on the model result that shows the profit distribution and checks in advance for the quality of the project to secure a sound profit in each project.

Analysis, Detection and Prediction of some of the Structural Motifs in Proteins

  • Guruprasad, Kunchur
    • Proceedings of the Korean Society for Bioinformatics Conference
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    • 2005.09a
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    • pp.325-330
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    • 2005
  • We are generally interested in the analysis, detection and prediction of structural motifs in proteins, in order to infer compatibility of amino acid sequence to structure in proteins of known three-dimensional structure available in the Protein Data Bank. In this context, we are analyzing some of the well-characterized structural motifs in proteins. We have analyzed simple structural motifs, such as, ${\beta}$-turns and ${\gamma}$-turns by evaluating the statistically significant type-dependent amino acid positional preferences in enlarged representative protein datasets and revised the amino acid preferences. In doing so, we identified a number of ‘unexpected’ isolated ${\beta}$-turns with a proline amino acid residue at the (i+2) position. We extended our study to the identification of multiple turns, continuous turns and to peptides that correspond to the combinations of individual ${\beta}$ and ${\gamma}$-turns in proteins and examined the hydrogen-bond interactions likely to stabilize these peptides. This led us to develop a database of structural motifs in proteins (DSMP) that would primarily allow us to make queries based on the various fields in the database for some well-characterized structural motifs, such as, helices, ${\beta}$-strands, turns, ${\beta}$-hairpins, ${\beta}$-${\alpha}$-${\beta}$, ${\psi}$-loops, ${\beta}$-sheets, disulphide bridges. We have recently implemented this information for all entries in the current PDB in a relational database called ODSMP using Oracle9i that is easy to update and maintain and added few additional structural motifs. We have also developed another relational database corresponding to amino acid sequences and their associated secondary structure for representative proteins in the PDB called PSSARD. This database allows flexible queries to be made on the compatibility of amino acid sequences in the PDB to ‘user-defined’ super-secondary structure conformation and vice-versa. Currently, we have extended this database to include nearly 23,000 protein crystal structures available in the PDB. Further, we have analyzed the ‘structural plasticity’ associated with the ${\beta}$-propeller structural motif We have developed a method to automatically detect ${\beta}$-propellers from the PDB codes. We evaluated the accuracy and consistency of predicting ${\beta}$ and ${\gamma}$-turns in proteins using the residue-coupled model. I will discuss results of our work and describe databases and software applications that have been developed.

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Effect of severe neonatal morbidities on long term outcome in extremely low birthweight infants

  • Koo, Kyo-Yeon;Kim, Jeong-Eun;Lee, Soon-Min;NamGung, Ran;Park, Min-Soo;Park, Kook-In;Lee, Chul
    • Clinical and Experimental Pediatrics
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    • v.53 no.6
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    • pp.694-700
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    • 2010
  • Purpose: To assess the validity of individual and combined prognostic effects of severe bronchopulmonary dysplasia (BPD), brain injury, retinopathy of prematurity (ROP), and parenteral nutrition associated cholestasis(PNAC). Methods: We retrospectively analyzed the medical records of 80 extremely low birthweight (ELBW) infants admitted to the neonatal intensive care unit (NICU) of the Severance Children's Hospital, and who survived to a postmenstrual age of 36 weeks. We analyzed the relationship between 4 neonatal morbidities (severe BPD, severe brain injury, severe ROP, and severe PNAC) and poor outcome. Poor outcome indicated death after a postmenstrual age of 36 weeks or survival with neurosensory impairment (cerebral palsy, delayed development, hearing loss, or blindness) between 18 and 24 months of corrected age. Results: Each neonatal morbidity correlated with poor outcome on univariate analysis. Multiple logistic regression analysis revealed that the odds ratios (OR) were 4.9 (95% confidence interval [CI], 1.0-22.6; $P$=0.044) for severe BPD, 13.2 (3.0-57.3; $P$<.001) for severe brain injury, 5.3 (1.6-18.1; $P$=0.007) for severe ROP, and 3.4 (0.5-22.7; $P$=0.215) for severe PNAC. Severe BPD, brain injury, and ROP were significantly correlated with poor outcome, but not severe PNAC. By increasing the morbidity count, the rate of poor outcome was significantly increased (OR 5.2; 95% CI, 2.2-11.9; $P$<.001). In infants free of the above-mentioned morbidities, the rate of poor outcome was 9%, while the corresponding rates in infants with 1, 2, and more than 3 neonatal morbidities were 46%, 69%, and 100%, respectively. Conclusion: In ELBW infants 3 common neonatal mornidifies, severe BPD, brain injury and ROP, strongly predicts the risk of poor outcome.

Estimation of the Optimal Harvest and Stock Assessment of Hairtail Caught by Multiple Fisheries (다수어업의 갈치 자원평가 및 최적어획량 추정)

  • Nam, Jongoh;Cho, Hoonseok
    • Ocean and Polar Research
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    • v.40 no.4
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    • pp.237-247
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    • 2018
  • This study aims to estimate optimal harvests, fishing efforts, and stock levels of hairtail harvested by the large pair bottom trawl, the large otter trawl, the large purse seine, the offshore long line, and the offshore angling fisheries by using the surplus production models and the current value Hamiltonian method. Processes of this study are as follows. First of all, this study estimates the standardized fishing efforts regarding the harvesting of the hairtail by the above five fishing gears based on the general linear model developed by Gavaris. Secondly, this study estimates environmental carrying capacity (k), intrinsic growth rate (r), and catchability coefficient (q) by applying the Clarke Yoshimoto Pooley (CY&P) model among various surplus production models. Thirdly, this study estimates the optimal harvests, fishing efforts, and stock levels regarding the hairtail by the current value Hamiltonian method, including the average landing price, the average unit cost, and the social discount rate. Finally, this study attempts a sensitivity analysis to figure out changes in optimal harvests, fishing efforts, and stock levels due to changes in the average landing price and the average unit cost. As results induced by the current value Hamiltonian method, the optimal harvests, fishing efforts, and stock levels regarding the hairtail caught by several fishing gears were estimated as 33,133 tons, 901,080 horse power, and 79,877 tons, respectively. In addition, from the results of the sensitivity analysis, first of all, if the average landing price of the hairtail constantly increases, the optimal harvests of it increase at a decreasing rate, and then harvests finally slightly decrease as a result of decreases in stock levels. Secondly, if the average unit cost of fishing efforts continuously increases, the optimal fishing efforts decreases, but optimal stock levels increase. Optimal harvests start climbing and then decrease continuously due to increases in the average unit cost. In summary, this study suggests that the optimal harvests (33,133 tons) were larger than actual harvests (25,133 tons), but the optimal fishing efforts (901,080 horse power) were much less than estimated standardized fishing efforts (1,277,284 horse power), corresponding to the average of the recent three years (2014-2016). This result implies that the hairtail has been inefficiently harvested and recently overfished due to excessive fishing efforts. Efficient management and conservation policies on stock levels need to be urgently implemented. Some appropriate strategies would be to include the hairtail in the Korean TAC species or to extend the closed fishing season for this species.

Analysis of Rainfall Runoff Reduction Effect Depending upon the Location of Detention Pond in Urban Area (도시유역 저류지 위치에 따른 우수유출저감효과 분석)

  • Lee, Jae Joon;Kim, Ho Nyun
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.28 no.5B
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    • pp.535-546
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    • 2008
  • Urbanization results in increased runoff volume and flowrate and shortening in time of concentration, which may cause frequent flooding downstream. The retardation structures are used to eliminate adverse downstream effects of urban stormwater runoff. There are various types of flow retardation measures include detention basin, retention basin, and infiltration basin. In this study, to present a rough standard about location of detention pond for attenuating peak flow of urban area, the runoff reduction effect is analyzed at outlet point when detention pond is located to upstream drainage than outlet. The runoff reduction effects are analyzed under the three assumed basins. These basins have longitudinal shape (SF = 0. 204), concentration shape (SF = 0. 782), and middle shape (SF = 0.567). Numerous variables in connection with the storage effect of detention pond and the runoff reduction effects are analyzed by changing the location of detention pond. To analyze runoff reduction effect by location of single detention pond, Dimensionless Upstream Area Ratio (DUAR) is changed to 20%, 40%, 60%, and 80% according to the basin shape. In case of multiple detention pond, DUAR is changed to 60%, 80%, 100%, 120%, and 140% only under the middle shape basin (SF = 0.567). Related figures and regression equations to determine the location of detention pond are obtained from above analysis of two cases in this study. These results can be used to determine the location of appropriate detention pond corresponding to the any runoff reduction such as storage ratio and peak flow ratio in urban watershed.