• 한국산학기술학회논문지
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• 제16권6호
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• pp.3661-3666
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• 2015

본 논문은 MDO에서 적용가능한 근사기법의 활용에 관한 연구를 수행하였다. MDO 통합 설계 시스템을 구축하는데 있어서, 최적화 과정에서 발생하는 수많은 반복 계산, 광범위한 다분야 간 설계 및 CAD/CAE와의 연계를 고려함으로써 발생하는 방대한 계산량 및 데이터의 정보량으로 인해 수반되는 계산 비용을 현저히 줄이지 않고는 통합설계 시스템을 실제로 구축한다 해도 그 효용성은 비현실적일 수밖에 없게 된다. 따라서 본 연구에서는 MDO 통합설계 시스템 프레임워크의 목적을 위해, 필수적으로 선행되어야 하는 다양한 근사기법의 적절한 활용을 통해 MDO에서 적용가능한 근사기법의 활용에 대한 연구를 수행하였다.

• 한국항공우주학회지
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• 제47권7호
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• pp.535-540
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• 2019

MDO(Multi-disciplinary Optimization)를 위한 서로 다른 모델 간의 결합은 계산 프레임 워크의 복잡성을 크게 증가시키는 동시에 CPU 시간과 메모리 사용을 증가시킨다. 이러한 어려움을 극복하기 위해 POD(Proper Orthogonal Decomposition)와 RBF(Radial Basis Function)를 사용하여 복합 샌드위치 구조가 항공기 날개 스킨 재료로 사용될 때 복합재와 샌드위치 코어의 두께를 결정하는 최적화 문제의 해를 구했다. POD와 RBF를 사용하여 날개 형상과 하중 데이터에 대한 대리 모델을 만들었으며 대리 모델에 의해 얻어진 목적 함수 및 제약 함수 값을 사용하여 최적해를 구하였다.

• 디지털융복합연구
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• 제17권4호
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• pp.229-238
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• 2019

본 연구는 간호대학생 고학년을 대상으로 자아탄력성, 진로결정자기효능감, 취업스트레스의 관계를 규명하고자 수행되었다. 간호대학생 3, 4학년 175명을 대상으로 자가보고식 설문조사를 실시하였고, stepwise multiple regression으로 분석하였다. 연구결과, 일반적 특성에 따른 자아탄력성은 대학생활 만족도에 따라, 진로결정자기효능감은 건강상태, 대학생활 만족도, 전공에 대한 만족도, 학업성적에 따라, 취업스트레스는 학년, 대학생활 만족도, 전공에 대한 만족도, 학업성적에 따라 통계적으로 유의한 차이가 있었다. 취업스트레스의 영향요인은 학년, 진로결정자기효능감, 대학생활 만족도로 나타났고, 설명력은 13.5%였다. 그러므로 학년, 대학생활 만족도룰 고려하여 진로결정자기효능감을 강화시키는 융복합적인 중재를 통해 간호대학생 고학년의 취업스트레스를 감소시켜나가야 할 것이다.

• Steel and Composite Structures
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• 제45권6호
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• pp.775-796
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• 2022

In this study, a new type of energy absorbers with a functionally graded thickness is investigated, these type of absorbers absorb energy through expanding-folding processes. The expanding-folding absorbers are composed of two sections: a thin-walled aluminum matrix and a thin-walled steel mandrel. Previous studies have shown higher efficiency of the mentioned absorbers compared to the conventional ones. In this study, the effect of thickness which has been functionally-graded on the aluminum matrix (in which expansion occurs) was investigated. To this end, initial functions were considered for the matrix thickness, which was ascending/descending along the axis. The study was done experimentally and numerically. Comparing the experimental data with the numerical results showed high consistency between the numerical and experimental results. In the final section of this study, the best energy absorber functionally graded thickness was introduced by optimization using a third-order genetic algorithm. The optimization results showed that by choosing a minimum thickness of 1.6 mm and the exponential coefficient of 3.25, the most optimal condition can be obtained for descending thickness absorbers.

• Journal of Chest Surgery
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• 제56권2호
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• pp.67-74
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• 2023

Perioperative treatment with conventional cytotoxic chemotherapy for resectable non-small cell lung cancer (NSCLC) has proven clinical benefits in terms of achieving a higher overall survival (OS) rate. With its success in the palliative treatment of NSCLC, immune checkpoint blockade (ICB) has now become an essential component of treatment, even as neoadjuvant or adjuvant therapy in patients with operable NSCLC. Both pre- and post-surgery ICB applications have proven clinical efficacy in preventing disease recurrence. In addition, neoadjuvant ICB combined with cytotoxic chemotherapy has shown a significantly higher rate of pathologic regression of viable tumors compared with cytotoxic chemotherapy alone. To confirm this, an early signal of OS benefit has been shown in a selected population, with programmed death ligand 1 expression ≥50%. Furthermore, applying ICB both pre- and post-surgery enhances its clinical benefits, as is currently under evaluation in ongoing phase III trials. Simultaneously, as the number of available perioperative treatment options increases, the variables to be considered for making treatment decisions become more complex. Thus, the role of a multidisciplinary team-based treatment approach has not been fully emphasized. This review presents up-to-date pivotal data that lead to practical changes in managing resectable NSCLC. From the medical oncologist's perspective, it is time to dance with surgeons to decide on the sequence of systemic treatment, particularly the ICB-based approach, accompanying surgery for operable NSCLC.

• 수완나부미
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• 제7권1호
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• pp.13-57
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• 2015

The paper brings together several strands of debate and deliberation in which I have been involved since the early 2000s on the definition of Southeast Asia and the rationale of Southeast Asian Studies. I refer to the relationship between area studies and methodologies as a conundrum (or puzzle), though I should state from the outset that I think it is much more of a conundrum for others than for me. I have not felt the need to pose the question of whether or not area studies generates a distinctive method or set of methods and research practices, because I operate from a disciplinary perspective; though that it is not to say that the question should not be posed. Indeed, as I have earned a reputation for "revisionism" and championing disciplinary approaches rather than regional ones, it might be anticipated already the position that I take in an examination of the relationships between methodologies and the practice of "area studies" (and in this case Southeast Asian [or Asian] Studies). Nevertheless, given the recent resurgence of interest in the possibilities provided by the adoption of regional perspectives and the grounding of data gathering and analysis within specified locations in the context of globalization, the issues raised for researchers working in Southeast Asia and within the field of Southeast Asian Studies require revisiting.

• 산경연구논집
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• 제15권4호
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• pp.11-18
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• 2024

Purpose: The primary purpose of this research is to investigate the multidisciplinary effect of food delivery apps (FDAs) in urban hotels in the wake of the lockdown due to Covid-19 pandemic. Specifically, the study aims: To explore and scrutinize the primary shifts in customer behavior and preferences in modern urban hotels, and to explore and scrutinize the primary shifts in customer behavior and preferences in modern urban hotels. Research design, data and methodology: This study conducted a systematic literature review to gather evidence of the FDA's effect on customer behavior and the hospitality industry during the Covid-19 pandemic. Complying with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) principles guarantees a structured and transparent method to search the literature and its analysis. Results: The result based on the systematic review has indicated that the booming business of food delivery at home companies and changing consumer tastes prove the FDA's growing circuit in the hotel industry, thus demonstrating their ability and power to adapt to changing trends. Conclusions: Therefore, this study concludes that using FDA's platform, future hospitality managers have to focus on agility in operations, innovation, and technology integration to keep up with changing consumer trends and market conditions.

• Korean Journal of Radiology
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• 제25권5호
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• pp.459-472
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• 2024

Hyperpolarized (HP) carbon-13 (¹³C) MRI represents an innovative approach for noninvasive, real-time assessment of dynamic metabolic flux, with potential integration into routine clinical MRI. The use of [1-¹³C]pyruvate as a probe and its conversion to [1-¹³C]lactate constitute an extensively explored metabolic pathway. This review comprehensively outlines the establishment of HP ¹³C-MRI, covering multidisciplinary team collaboration, hardware prerequisites, probe preparation, hyperpolarization techniques, imaging acquisition, and data analysis. This article discusses the clinical applications of HP ¹³C-MRI across various anatomical domains, including the brain, heart, skeletal muscle, breast, liver, kidney, pancreas, and prostate. Each section highlights the specific applications and findings pertinent to these regions, emphasizing the potential versatility of HP ¹³C-MRI in diverse clinical contexts. This review serves as a comprehensive update, bridging technical aspects with clinical applications and offering insights into the ongoing advancements in HP ¹³C-MRI.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• 제27권3호
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• pp.146-157
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• 2024

Purpose: Celiac disease (CD) is one of the most prevalent food-related illnesses in children, with a global prevalence of approximately 1.4%. CD can create an emotional burden, particularly on mothers, who are mainly responsible for managing challenges related to adherence to a gluten-free diet, high food costs, and food problems in schools and social areas. There is a gap in the literature, and parental experiences of raising children with CD should be explicitly examined. This qualitative study sought to provide insights into the experiences of parents raising a child with CD in the Turkish context. Methods: This study used a descriptive qualitative research methodology and conducted individual semi-structured video-based dyadic interviews with 19 parents. Results: Participants experienced both challenges and motivators through management of their children's CD. Analyses of the interview transcripts through the data uncovered three main themes focusing primarily on parental concerns: (1) parental challenges in child's disease management, (2) supportive care needs, and (3) parental expectations. Conclusion: A multidisciplinary team should approach the child and family immediately after diagnosis, and facilities should support parents with continuing education and psychological, financial, and social assistance.

• Journal of Preventive Medicine and Public Health
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• 제57권2호
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• pp.157-166
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• 2024

Objectives: Children with disabilities may exhibit a multitude of symptoms, and treatment requires a multidisciplinary approach for a satisfactory outcome. Lack of awareness among physicians, lack of referral, and lack of inter-sectoral coordination have hindered paediatric practice in Tamil Nadu, a state in India with a striking childhood disability rate that warrants a timely interdisciplinary approach. However, the perspectives of paediatricians on paediatric physiotherapy are unknown. The aim of the study was to investigate the perspectives of practicing paediatric physicians in Chennai on the role of physiotherapy in paediatrics. Methods: For an in-depth exploration, qualitative semi-structured interviews were conducted in person with 10 paediatricians. Audio from the sessions was recorded and transcribed, and data saturation was achieved through iterative analysis. Results: A grounded theory analysis of the results yielded 5 domains under which the perspectives and expectations of the physicians were described, along with the barriers experienced by patients' parents as explained by their paediatrician. The responses highlighted deficits in awareness, structural support, accessibility and direct communication between physicians and physiotherapists. Conclusions: Paediatric physicians have different opinions, and some ignorance persists concerning paediatric physiotherapy. This study warrants a proper structure of the paediatric rehabilitation unit and regular interdisciplinary meetings and focus group discussions to increase access for parents and improve patient outcomes.