• 토지주택연구
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• 제14권2호
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• pp.97-107
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• 2023

본 연구는 자연 재해 및 사회 재난 발생으로 주거권의 보장을 위한 임시주거 시설의 수요가 증가하는 추세에 대비하여 이재민에게 신속하게 양질의 주택을 공급코자 수행되었다. 대량 생산 및 운반에 효율적인 계획 모델을 만들기에 적합한 DfMA 설계 방식, 즉 제조 및 조립 기반 모듈러주택 모델을 제시하였으며, 특징은 다음 세 가지이다. 첫째, 모듈러주택을 서비스 모듈과 기능 모듈로 구분하여 고정성과 변동성을 발전시켜 다양성을 만들도록 계획했다. 둘째, 제품과 같이 이동하여 편리한 위치에 놓고 사용할 수 있도록 계획하여 대지 여건 및 수요에 맞춰 융통성 있는 배치계획을 하는 시스템을 제안 했다. 이러한 계획은 동일한 주택을 대량 생산하여 국내외의 다양한 위치와 사업에 활용할 수 있다. 셋째, 생산효율성을 높일 수 있도록 생산의 자동화를 염두해 두고 건식 공법으로 공정을 단순화하고 최소화하는 방식으로 계획했다. 이러한 DfMA설계방식 적용으로 제작 및 시공기간 단축, 공사비 절감, 주택 품질 제고를 도모하여 건설 생산성을 향상시킬 수 있다.

• 천문학회보
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• 제46권1호
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• pp.46.1-46.1
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• 2021

Hydrated asteroids get widespread attention for the evolution of water in the Solar System, especially thanks to the recent successes of the Hayabusa2 and OSIRIS-REx space missions. The target asteroids of these missions are believed to be fragments that have experienced aqueous alteration in their parent bodies [3]. Although hydrated asteroids have been studied well via spectroscopy, focusing on the 0.7 um or the 2.7 um absorption bands [2, 3, 4], polarimetric properties of these asteroids have rarely been investigated. In this study, we conducted a polarimetric observation of 18 C-complex main-belt asteroids with the 1.6-m Pirka telescope at the Nayoro Observatory of Hokkaido University, Japan. We used a polarimetric imaging mode of the Multi-Spectral Imager (MSI) with the standard Rc-band filter (the central wavelength at 0.64 um) [5]. As a result, we found that all of these hydrated asteroids indicate deep negative branches of their polarimetric profiles. Accordingly, the hydrated asteroids have the polarization minima (Pmin), whose values are significantly lower than any other taxonomic types of asteroids (including C-group asteroids). Because Pmin depends on albedo, particle size, and porosity of the surface materials [1], we suspect that hydrated asteroids are distinctive from other asteroids in terms of these physical properties. In this presentation, we introduce our polarimetric observation and findings. We discuss why hydrated asteroids indicate such low Pmin values, comparing Pmin with spectral features at 0.7 um and 2.7 um based on the observation results.

• Journal of Genetic Medicine
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• 제20권1호
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• pp.6-14
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• 2023

Fabry disease (FD), a rare X-linked lysosomal storage disorder, is caused by mutations in the α-galactosidase A gene gene encoding α-galactosidase A (α-Gal A). The functional deficiency of α-Gal A results in progressive accumulation of neutral glycosphingolipids, causing multi-organ damages including cardiac, renal, cerebrovascular systems. The current treatment is comprised of enzyme replacement therapy (ERT), oral pharmacological chaperone therapy and adjunctive supportive therapy. ERT has been introduced 20 years ago, changing the outcome of FD patients with proven effectiveness. However, FD patients have many unmet needs. ERT needs a life-long intravenous therapy, inefficient bio-distribution, and generation of anti-drug antibodies. Migalastat, a pharmacological chaperone, augmenting α-Gal A enzyme activity only in patients with mutations amenable to the therapy, is now available for clinical practice. Furthermore, these therapies should be initiated before the organ damage becomes irreversible. Development of novel drugs aim at improving the clinical effectiveness and convenience of therapy. Clinical trial of next generation ERT is underway. Polyethylene glycolylated enzyme has a longer half-life and potentially reduced antigenicity, compared with standard preparations with longer dosing interval. Moss-derived enzyme has a higher affinity for mannose receptors, and seems to have more efficient access to podocytes of kidney which is relatively resistant to reach by conventional ERT. Substrate reduction therapy is currently under clinical trial. Gene therapy has now been started in several clinical trials using in vivo and ex vivo technologies. Early results are emerging. Other strategic approaches at preclinical research level are stem cell-based therapy with genome editing and systemic mRNA therapy.

• 분석과학
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• 제22권6호
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• pp.449-457
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• 2009

국내에 유통 중인 식품을 대상으로 PCBs 62종 동족체를 동위원소희석법으로 분석하고 노출평가를 실시하였다. 시료에 $^{13}C$-labeled된 회수율 측정용 표준용액을 가하여 추출하고 다층 칼럼 크로마토그래피로 정제하여 HRGC/MSD로 분석하였다. 식품 중 평균 검출량(ng/g)은 쌀 0.13, 육류 1.8~3.4, 우유 및 유가공품 0.3~3.7, 계란 10.0, 수산물 0.8~34.4 이었다. 식품군별 검출분포는 수산물(94.4%) >육류 (2.3%) >알류(1.7%) > 우유 및 유가공품(1.3%) >쌀(0.3%) 순이었다. 식품을 통한 총 PCBs의 1일 노출량은 14.5 ng/kg bw/day로 건강상 안전한 것으로 평가되었다.

• 대한토목학회논문집
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• 제28권3D호
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• pp.417-422
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• 2008

전통적인 정사영상 제작기법으로는 이중 투영으로 인한 원치 않는 구조물의 중복이 정사영상 안에 생길 수 있다. 특히 고층 빌딩이 밀집된 도심지역에서는 고도의 변화가 심하여 이러한 현상이 자주 발생한다. 이러한 문제들로 인하여 도심지역의 폐색영역 탐지는 정확한 엄밀 정사영상(true orthophoto)의 제작에 있어서 매우 중요한 문제이다. 본 논문은 항공영상과 LiDAR로부터 가시고도 기반의 폐색영역 탐지기법을 다루고 있다. 본 논문에서는 LiDAR의 포인트 클라우드 데이터로부터 격자형태의 수치표고모형(DSM)을 제작한 후, DSM과 항공영상의 촬영점을 이용한 가시고도 기반의 폐색영역 탐지기법을 제안하였다. 마지막으로 만들어진 DSM과 전 과정에서 만들어진 폐색맵을 이용한 엄밀 정사영상의 제작과정을 기술하였다. 제안된 알고리즘은 미국 인디애나 주의 퍼듀 캠퍼스 지역에 적용되었다.

• 대한토목학회논문집
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• 제30권4D호
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• pp.403-411
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• 2010

우리나라는 1990년대부터 도시공간구조 재배치와 지역 간 균형발전계획에 따라, 경전철, 모노레일, 자기부상열차, 간선급행버스 등 신교통수단 도입이 구체적으로 논의되어 왔고 일부는 건설 중에 있다. 그러나 경량전철 사업추진과정에서 일관성 있게 조율할 수 있는 전담기구역할이 부족하여 사업주체간에 심각한 혼선을 빗고 있으며, KDI 공공투자관리센터에서 시행하고 있는 예비타당성조사도 경제성(B/C)에만 비중을 두고 사업을 시행하고 있는 형편이다. 따라서 경량전철형식에 대한 적정성 연구가 필요함으로 도시별 유형과 특성에 맞는 효율적인 경량전철형식을 제시하고자 한다. 이를 위해 본 연구에서는 서울과 경기도의 지역을 요인분석을 이용하여 6개 군집으로 분류하고 각 군집에 적합한 경량전철을 선정하기 위해 선호도 분석을 실시하였다.

• Smart Structures and Systems
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• 제30권5호
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• pp.479-500
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• 2022

In this study, a new type of isolation bearing is proposed by combining S-shaped steel plate dampers (SSDs) with a spherical steel bearing, and the seismic control effect of a five-span standard high-speed railway bridge is investigated. The advantages of the proposed S-shaped steel damping friction bearing (SSDFB) are that it cannot only lengthen the structural periods, dissipate the seismic energy, but also prevent bridge unseating due to the restraint effectiveness of SSDs in the large relative displacements between the girders and piers. This study first presents a detailed description and working principle of the SSDFB. Then, mechanical modeling of the SSDFB was derived to fundamentally define its cyclic behavior and obtain key mechanical parameters. The numerical model of the SSDFB's critical component SSD was verified by comparing it with the experimental results. After that, parameter studies of the dimensions and number of SSDs, the friction coefficient, and the gap length of the SSDFBs were conducted. Finally, the longitudinal seismic responses of the bridge with SSDFBs were compared with the bridge with spherical bearing and spherical bearing with strengthened shear keys. The results showed that the SSDFB can not only significantly mitigate the shear force responses and residual displacement in bridge substructures but also can effectively reduce girder displacement and prevent bridge unseating, at a cost of inelastic deformation of the SSDs, which is easy to replace. In conclusion, the SSDFB is expected to be a cost-effective option with both multi-stage energy dissipation and restraint capacity, making it particularly suitable for seismic isolation application to high-speed railway bridges.

• 국제학술발표논문집
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• The 5th International Conference on Construction Engineering and Project Management
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• pp.640-647
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• 2013

Building Information Modelling (BIM) has become the new international benchmark for efficiency in design, construction and maintenance of buildings. It is the platform that brings about collaboration between project stakeholders and improvement of project outcomes. With all its potentials, not much of the impact of BIM technologies has been felt in the Nigerian construction industry. This research aimed at assessing the readiness of the Nigerian building design firms to adopt BIM technologies. The research was exploratory in nature. A field survey was conducted with the use of structured questionnaire, self administered to a sample of building design consultancy firms (architectural, structural, M&E, quantity surveying, and multi-disciplinary design firms) within Abuja and Kaduna. The questionnaire sought the perception of the responding firms on the factors affecting BIM adoption in the Nigerian construction industry, and their level of readiness to adopt BIM technologies in their practices based on the four categories of readiness-management, people, process and technology. 42.26% response rate was achieved and used for analysis. ANOVA and DUNCAN post-hoc tests were used to establish the differences between the responses of the groups of firms, while means and standard deviations were obtained to establish the important factors affecting BIM adoption in Nigeria. The survey revealed that all the groups of Nigerian design firms are appreciably ready for the adoption of BIM technologies in their practice, with slight variations in their respective levels of readiness. 'Lack of awareness of BIM technology among professionals' and clients and 'lack of knowledgeable and experienced partners' were identified as the most important barriers of BIM adoption in Nigeria; while the most significant drivers are 'availability of well trained professionals' and 'cooperation and commitment of professional bodies to the adoption'. Education and training of building design professionals and cooperation of all stakeholders in the design and construction supply chain were recommended as part of measures to ensure successful adoption of BIM in the Nigerian construction industry.

• 한국산업정보학회논문지
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• 제28권6호
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• pp.107-113
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• 2023

저장성능이 중요하게 인식되는 탄약분야에 있어서 포장용기의 방습성능은 크게 강조되어 왔다. 탄약분야에서는 주로 다중 적층구조를 갖는 지환통이 포장용기로 사용되고 있는데, 이는 다양한 역할을 하는 재료를 적층하여 만들어진다. 이러한 포장용기는 주로 한국산업규격 KS T 1314에 따라 방습성능을 평가하게 되며, 내부에 투입된 흡습제의 무게 변화에 대하여 선형 회귀분석을 통하여 투습도가 결정된다. 본 연구에서는 흡습제 투입량이 포장용기의 투습도 시험 결과에 미치는 영향을 확인하였다. 탄약 포장용기로 사용되는 지환통의 평가 시, 사용되는 흡습제의 양은 내부 용적의 약 70 % 이상이 타당한 것으로 판단된다.

• 한국의료질향상학회지
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• 제29권2호
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• pp.2-14
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• 2023

Purpose: This study aimed to identify strategies to enhance the competencies of patient safety coordinators in Korea. Methods: Fourteen participants from nine hospitals were interviewed between May and November 2022. Qualitative content analysis was used to analyze the data. Results: As for the strategies to enhance patient safety management competency, 3 themes and 11 sub-themes were derived. The first theme was 'Having individual competence as a patient safety coordinator', and the sub-themes were 'Communication skills with members', 'Flexible thinking from multiple perspectives', and 'Preparing for administrative work competencies that they had not experienced as a nurse.' The second theme was 'Responding strategically to promote improvement activities', and the sub-themes for it were 'Multi-angle approach to the problem', 'A careful approach so as not to be taken as criticism in the field', 'Increasing the possibility of improvement activities through awareness', 'Activating the network between patient safety coordinators', and 'Expanding learning opportunities through patient safety case analysis.' The third theme was 'Obtaining support to facilitate patient safety activities', and the sub-themes for this were 'Improving staff awareness of patient safety', 'Providing a training course for nurse professional of patient safety', and 'Expanding the manpower allocation standard of patient safety coordinators.' Conclusion: This study explored personal competencies such as document writing and computer utilization capabilities, focused on ways to improve the field of patient safety management, and emphasized the need for organizational and political support.