• Land and Housing Review
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• v.14 no.2
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• pp.97-107
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• 2023

This study examined how to better provide quality temporary housing for people in the event of natural and social disasters. Design for Manufacture and Assembly (DfMA) is suitable for creating an efficient planning model for the mass production and transport of a modular house. The proposed DfMA model has the following three characteristics. First is the division of the modular house into service modules and functional modules and to create diversity by developing standard parts and multi-functional parts. Second is a flexible layout suitable for various site conditions. Such flexible layouts would allow identical homes to be mass produced and deployed to a variety of locations, both nationally and internationally. Third is to simplify and minimize the automation process with dry construction to increase production efficiency. Application of this DfMA design method can lead to reduced construction time and cost and improve housing quality.

• The Bulletin of The Korean Astronomical Society
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• v.46 no.1
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• pp.46.1-46.1
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• 2021

Hydrated asteroids get widespread attention for the evolution of water in the Solar System, especially thanks to the recent successes of the Hayabusa2 and OSIRIS-REx space missions. The target asteroids of these missions are believed to be fragments that have experienced aqueous alteration in their parent bodies [3]. Although hydrated asteroids have been studied well via spectroscopy, focusing on the 0.7 um or the 2.7 um absorption bands [2, 3, 4], polarimetric properties of these asteroids have rarely been investigated. In this study, we conducted a polarimetric observation of 18 C-complex main-belt asteroids with the 1.6-m Pirka telescope at the Nayoro Observatory of Hokkaido University, Japan. We used a polarimetric imaging mode of the Multi-Spectral Imager (MSI) with the standard Rc-band filter (the central wavelength at 0.64 um) [5]. As a result, we found that all of these hydrated asteroids indicate deep negative branches of their polarimetric profiles. Accordingly, the hydrated asteroids have the polarization minima (Pmin), whose values are significantly lower than any other taxonomic types of asteroids (including C-group asteroids). Because Pmin depends on albedo, particle size, and porosity of the surface materials [1], we suspect that hydrated asteroids are distinctive from other asteroids in terms of these physical properties. In this presentation, we introduce our polarimetric observation and findings. We discuss why hydrated asteroids indicate such low Pmin values, comparing Pmin with spectral features at 0.7 um and 2.7 um based on the observation results.

• Journal of Genetic Medicine
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• v.20 no.1
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• pp.6-14
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• 2023

Fabry disease (FD), a rare X-linked lysosomal storage disorder, is caused by mutations in the α-galactosidase A gene gene encoding α-galactosidase A (α-Gal A). The functional deficiency of α-Gal A results in progressive accumulation of neutral glycosphingolipids, causing multi-organ damages including cardiac, renal, cerebrovascular systems. The current treatment is comprised of enzyme replacement therapy (ERT), oral pharmacological chaperone therapy and adjunctive supportive therapy. ERT has been introduced 20 years ago, changing the outcome of FD patients with proven effectiveness. However, FD patients have many unmet needs. ERT needs a life-long intravenous therapy, inefficient bio-distribution, and generation of anti-drug antibodies. Migalastat, a pharmacological chaperone, augmenting α-Gal A enzyme activity only in patients with mutations amenable to the therapy, is now available for clinical practice. Furthermore, these therapies should be initiated before the organ damage becomes irreversible. Development of novel drugs aim at improving the clinical effectiveness and convenience of therapy. Clinical trial of next generation ERT is underway. Polyethylene glycolylated enzyme has a longer half-life and potentially reduced antigenicity, compared with standard preparations with longer dosing interval. Moss-derived enzyme has a higher affinity for mannose receptors, and seems to have more efficient access to podocytes of kidney which is relatively resistant to reach by conventional ERT. Substrate reduction therapy is currently under clinical trial. Gene therapy has now been started in several clinical trials using in vivo and ex vivo technologies. Early results are emerging. Other strategic approaches at preclinical research level are stem cell-based therapy with genome editing and systemic mRNA therapy.

• Analytical Science and Technology
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• v.22 no.6
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• pp.449-457
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• 2009

Total PCBs (62 congeners) has been determined in the retailed foods by the isotopic dilution method and the exposure assessment has been performed. Put into a food sample $^{13}C$-labeled standard for recovery was added and then it was extracted, cleaned-up by multi-layer column chromatography and then analyzed by HRGC/MS. The average levels (ng/g) detected was 0.1 for rice, 1.8~3.4 for meats, 0.3~3.7 for milk and dairy products, 10.0 for egg and 0.8~34.4 for fishes. Distribution of total PCBs was in order of fishes (94.4%) > meats (2.3%) > eggs (1.7%) > milk and dairy products (1.3%) > rice (0.3%). The estimated daily intake(EDI) was 14 ng/kg bw/day. It was concluded that there was no health risk at all.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.28 no.3D
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• pp.417-422
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• 2008

With standard orthorectification algorithms, one can produce unacceptable structure duplication in the orthophoto due to the double projection. Because of the abrupt height differences, such structure duplication is a frequently occurred phenomenon in the dense urban area which includes multi-history buildings. Therefore, occlusion area detection especially for the urban area is a critical issue in generation of true orthophoto. This paper deals with occlusion area detection with visible height based approach from aerial imagery and LiDAR. In order to accomplish this, a grid format DSM is produced from the point clouds of LiDAR. Next, visible height based algorithm is proposed to detect the occlusion area for each camera exposure station with DSM. Finally, generation of true orthophoto is presented with DSM and previously produced occlusion maps. The proposed algorithms are applied in the Purdue campus, Indiana, USA.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.30 no.4D
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• pp.403-411
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• 2010

Nowadays, Light railway system is attracted public attention as solution for metropolitan traffic congestion. But it is difficult to decide an appropriate light railway system. It is especially hard in the Seoul metropolitan to decide an appropriate system, because there are many factors that must considered. So we research application status of light railway system that is scheduled or promoted in the Korea and the foreign nations. And we selected systems by types of city. In this paper, we divided into 6 types of city through factor analysis and cluster. And we considered various factor such as technology, transportation, environment etc that used previous research and feasibility study. To determine the priority among the factors, AHP(Analytic Hierarchy Process) was applied as a method for multi-standard decision method.

• Smart Structures and Systems
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• v.30 no.5
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• pp.479-500
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• 2022

In this study, a new type of isolation bearing is proposed by combining S-shaped steel plate dampers (SSDs) with a spherical steel bearing, and the seismic control effect of a five-span standard high-speed railway bridge is investigated. The advantages of the proposed S-shaped steel damping friction bearing (SSDFB) are that it cannot only lengthen the structural periods, dissipate the seismic energy, but also prevent bridge unseating due to the restraint effectiveness of SSDs in the large relative displacements between the girders and piers. This study first presents a detailed description and working principle of the SSDFB. Then, mechanical modeling of the SSDFB was derived to fundamentally define its cyclic behavior and obtain key mechanical parameters. The numerical model of the SSDFB's critical component SSD was verified by comparing it with the experimental results. After that, parameter studies of the dimensions and number of SSDs, the friction coefficient, and the gap length of the SSDFBs were conducted. Finally, the longitudinal seismic responses of the bridge with SSDFBs were compared with the bridge with spherical bearing and spherical bearing with strengthened shear keys. The results showed that the SSDFB can not only significantly mitigate the shear force responses and residual displacement in bridge substructures but also can effectively reduce girder displacement and prevent bridge unseating, at a cost of inelastic deformation of the SSDs, which is easy to replace. In conclusion, the SSDFB is expected to be a cost-effective option with both multi-stage energy dissipation and restraint capacity, making it particularly suitable for seismic isolation application to high-speed railway bridges.

• International conference on construction engineering and project management
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• 2013.01a
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• pp.640-647
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• 2013

Building Information Modelling (BIM) has become the new international benchmark for efficiency in design, construction and maintenance of buildings. It is the platform that brings about collaboration between project stakeholders and improvement of project outcomes. With all its potentials, not much of the impact of BIM technologies has been felt in the Nigerian construction industry. This research aimed at assessing the readiness of the Nigerian building design firms to adopt BIM technologies. The research was exploratory in nature. A field survey was conducted with the use of structured questionnaire, self administered to a sample of building design consultancy firms (architectural, structural, M&E, quantity surveying, and multi-disciplinary design firms) within Abuja and Kaduna. The questionnaire sought the perception of the responding firms on the factors affecting BIM adoption in the Nigerian construction industry, and their level of readiness to adopt BIM technologies in their practices based on the four categories of readiness-management, people, process and technology. 42.26% response rate was achieved and used for analysis. ANOVA and DUNCAN post-hoc tests were used to establish the differences between the responses of the groups of firms, while means and standard deviations were obtained to establish the important factors affecting BIM adoption in Nigeria. The survey revealed that all the groups of Nigerian design firms are appreciably ready for the adoption of BIM technologies in their practice, with slight variations in their respective levels of readiness. 'Lack of awareness of BIM technology among professionals' and clients and 'lack of knowledgeable and experienced partners' were identified as the most important barriers of BIM adoption in Nigeria; while the most significant drivers are 'availability of well trained professionals' and 'cooperation and commitment of professional bodies to the adoption'. Education and training of building design professionals and cooperation of all stakeholders in the design and construction supply chain were recommended as part of measures to ensure successful adoption of BIM in the Nigerian construction industry.

• Journal of Korea Society of Industrial Information Systems
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• v.28 no.6
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• pp.107-113
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• 2023

In the field of ammunition, storage performance is recognized as important, and the moisture-proof performance of packaging containers is very important. In the ammunition field, paper cans with a multi-layered structure are mainly used as packaging containers. It is made by layering materials that play various roles. These packaging containers are mainly evaluated for moisture-proof performance according to the Korean Industrial Standard KS T 1314. The moisture permeability is determined through linear regression analysis of the change in weight of the moisture absorbent added inside. In this study, the effect of the amount of desiccant added on the moisture permeability test results of packaging containers was confirmed. It is considered appropriate that the amount of desiccant used in testing ammunition packaging containers be approximately 70% or more of the internal volume.

• Quality Improvement in Health Care
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• v.29 no.2
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• pp.2-14
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• 2023

Purpose: This study aimed to identify strategies to enhance the competencies of patient safety coordinators in Korea. Methods: Fourteen participants from nine hospitals were interviewed between May and November 2022. Qualitative content analysis was used to analyze the data. Results: As for the strategies to enhance patient safety management competency, 3 themes and 11 sub-themes were derived. The first theme was 'Having individual competence as a patient safety coordinator', and the sub-themes were 'Communication skills with members', 'Flexible thinking from multiple perspectives', and 'Preparing for administrative work competencies that they had not experienced as a nurse.' The second theme was 'Responding strategically to promote improvement activities', and the sub-themes for it were 'Multi-angle approach to the problem', 'A careful approach so as not to be taken as criticism in the field', 'Increasing the possibility of improvement activities through awareness', 'Activating the network between patient safety coordinators', and 'Expanding learning opportunities through patient safety case analysis.' The third theme was 'Obtaining support to facilitate patient safety activities', and the sub-themes for this were 'Improving staff awareness of patient safety', 'Providing a training course for nurse professional of patient safety', and 'Expanding the manpower allocation standard of patient safety coordinators.' Conclusion: This study explored personal competencies such as document writing and computer utilization capabilities, focused on ways to improve the field of patient safety management, and emphasized the need for organizational and political support.