• 제목/요약/키워드: multi-loop structure

검색결과 88건 처리시간 0.034초

효과적인 siRNA의 디자인 (Designing An Effective siRNA)

  • 구남진;조광휘
    • Bioinformatics and Biosystems
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    • 제2권1호
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    • pp.17-23
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    • 2007
  • Short interfering RNA(siRNA)는 특별한 gene의 발현을 막는데 사용될 수 있고 그 gene의 기능과 치료의 적용에 많은 가능성을 가지고 있지만, 효과적인 siRNA를 디자인하는 방법은 아직까지 명확하지 않다. 효과적인 siRNA는 서열적인 경향을 가지고 있는데 낮은 G/C content, Sense strand의 3' 끝에 적은 안정성과 1번 위치에는 G/C, 19번 위치에는 A/U의 존재 여부를 들 수 있다. 이러한 특성 말고도 최근에는 mRNA의 2차구조가 RNAi 작용에 중요한 역할을 하게 되는데 복잡한 구조(hairpin, multi loop)를 가지고 수소결합을 많이 하여 안정한 상태에 있는 부분은 siRNA의 기능을 크게 줄어들게 한다. 또한, siRNA가 특정한 mRNA에 작동하도록 BLAST 검색을 하여 부작용의 가능성을 배제한다.

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다층상구조물의 강인 진동제어에 관한 연구 (A Study of Robust Vibration Control for a Multi-Layer Structure)

  • 김창화;정병건;정해종
    • Journal of Advanced Marine Engineering and Technology
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    • 제33권8호
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    • pp.1212-1219
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    • 2009
  • 본 연구에서는 실용설계의 새로운 도구로써 제어계의 강인성, 성능, 안정성 등의 설계지침을 정량화하기 쉽고 해가 효율적으로 구해져 주목받는 선형행렬부등식을 이용하여 강인한 LMI 제어기를 설계한다. 우선 다층상 구조물의 진동제어를 위해 수학적 모델링을 행하고 적분형 서보계를 적용한 LMI 제어 기법으로 상태 피드백 제어칙을 설계한다. 다음으로 설계한 제어칙으로 시스템 불확실성의 변동에 대해 시간영역의 설계사양을 고려한 경우와 고려하지 않은 경우에 대하여 시뮬레이션을 행하고 실제 적용 가능성을 검토한다.

한국의 미래 에너지사회 전망에 관한 연구 : 계층분석법과 인과지도의 보완적 분석을 중심으로 (A Research on the Prospect for the Future Energy Society in Korea: Focused on the Complementary Analysis of AHP and Causal Loop Diagram)

  • 황병용;최한림;안남성
    • 한국시스템다이내믹스연구
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    • 제11권3호
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    • pp.61-86
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    • 2010
  • This research analyzed on the future energy society of Korea in 2030 using system thinking approach. Key uncertainty factors determining the future energy society were analyzed in a multi disciplinary view point such as politics, economy, society, ecology and technology. Three causal loop diagrams for the future energy system in Korea and related policy leverages were shown as well. 'Global economic trends', 'change of industrial structure' and 'energy price' were identified as key uncertainty factors determining the Korean energy future. Three causal loop diagrams named as 'rate of energy self-sufficiency and alternative energy production', 'economic activity and energy demand' and 'Excavation of new growth engines' were developed. We integrated those causal loop diagrams into one to understand the entire energy system of the future, proposed three strategic scenarios(optimistic, pessimistic and most likely) and discussed implications and limits of this research.

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3-D Structure of a Coronal Jet Seen in Hinode, SDO, and STEREO

  • Lee, Kyoung-Sun;Innes, Davina;Moon, Yong-Jae;Shibata, Kazunari
    • 천문학회보
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    • 제36권2호
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    • pp.89.1-89.1
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    • 2011
  • We have investigated a coronal jet near the limb on 2010 June 27 by Hinode/X-Ray Telescope (XRT), EUV Imaging Spectrograph (EIS), Solar Optical Telescope (SOT), SDO/Atmospheric Imaging Assembly (AIA), and STEREO. From EUV (AIA and EIS) and soft X-ray (XRT) images we identify the erupting jet feature in cool and hot temperatures. It is noted that there was a small loop eruption in Ca II images of the SOT before the jet eruption. Using high temporal and multi wavelength AIA images, we found that the hot jet preceded its associated cool jet. The jet also shows helical-like structures during the rising period. According to the spectroscopic analysis, the jet structure changes from blue shift to red one with time, implying the helical structure of the jet. The STEREO observation, which enables us to observe this jet on the disk, shows that there was a dim loop associated with the jet. Comparing the observations from the AIA and STEREO, the dim loop corresponds to the jet structure which implies the heated loop. Considering that the structure of its associated active region seen in STEREO is similar to that in AIA observed 5 days before, we compared the jet morphology on the limb with the magnetic fields extrapolated from a HMI vector magnetogram observed on the disk. Interestingly, the comparison shows that the open field corresponds to the jet which is seen as the dim loop in STEREO. Our observations (XRT, SDO, SOT, and STEREO) are well consistent with the numerical simulation of the emerging flux reconnection model.

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주기 조정과 커널 자동 생성을 통한 다중 루프 시스템의 구현 (Synthesizing multi-loop control systems with period adjustment and Kernel compilation)

  • 홍성수;최종호;박홍성
    • 제어로봇시스템학회논문지
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    • 제3권2호
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    • pp.187-196
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    • 1997
  • This paper presents a semi-automatic methodology to synthesize executable digital controller saftware in a multi-loop control system. A digital controller is described by a task graph and end-to-end timing requirements. A task graph denotes the software structure of the controller, and the end-to-end requirements establish timing relationships between external inputs and outputs. Our approach translates the end-to-end requirements into a set of task attributes such as task periods and deadlines using nonlinear optimization techniques. Such attributes are essential for control engineers to implement control programs and schedule them in a control system with limited resources. In current engineering practice, human programmers manually derive those attributes in an ad hoc manner: they often resort to radical over-sampling to safely guarantee the given timing requirements, and thus render the resultant system poorly utilized. After task-specific attributes are derived, the tasks are scheduled on a single CPU and the compiled kernel is synthesized. We illustrate this process with a non-trivial servo motor control system.

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공정제어 구조합성에서의 상호작용 해석 (Interaction Analysis in Process Control System Structure Synthesis)

  • 고재욱
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 1987년도 한국자동제어학술회의논문집; 한국과학기술대학, 충남; 16-17 Oct. 1987
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    • pp.643-646
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    • 1987
  • A criterion is developed for the, selection of the best pairing of the control and manipulated variables and for the interaction analysis of decentralized multi-input multi-output control systems. This criterion is based on the difficulty caused by the interaction terms in finding the in-verse of the block steady gain matrix. A quantitative measure of the best pairing is obtained from the resemblance of a set of independent block multi-loop systems. Several examples show the validity of the pairing criterion.

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신경회로망을 이용한 열성층 풍동내의 온도 분포 제어 (Control of temperature distribution in a thermal stratified tunnel by using neural networks)

  • 부광석;김경천
    • 제어로봇시스템학회:학술대회논문집
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    • 제어로봇시스템학회 1996년도 한국자동제어학술회의논문집(국내학술편); 포항공과대학교, 포항; 24-26 Oct. 1996
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    • pp.147-150
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    • 1996
  • This paper describes controller design and implementation method for controlling the temperature distribution in a thermal stratified wind tunnel(TSWT) by using a neural network algorithm. It is impossible to derive a mathematical model of the relation between heat inputs and temperature outputs in the test section of the TSWT governed by a nonlinear turbulent flow. Thus inverse neural network models with a multi layer perceptron structure are used in a feedforward control loop and feedback control loop to generate an arbitrary temperature distribution in the test section of the TSWT.

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서울시민의 보행과 건강증진에 관한 시스템 사고 기반의 구조 탐색 (A systems thinking approach to explore the structure of urban walking and health promotion in Seoul)

  • 김동하;정창권;이지현;김광기;제갈정;유승현
    • 보건교육건강증진학회지
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    • 제35권5호
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    • pp.1-16
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    • 2018
  • Objectives: This study aimed to examine systems behavior of urban walking by analyzing a dynamic structure in Seoul, South Korea. Methods: As a systems thinking approach to urban walking and health promotion, we developed a Casual Loop Diagram based on literature review and expert consultation. The reviewed literature included: 1) qualitative studies that explores the experiences of urban walkers in Seoul; 2) a systematic review study on the built environmental factors related to walking; 3) policy research reports related to urban walking in Seoul. Results: The feedback structure for urban walking was related to the three urban environments (safety & walking environment, socioeconomic environment, and public transportation environment), and was characterized by a trade-off consisting of eight reinforcing loops and four balancing loops. Conclusions: The policies for a walkable city require multi-sectoral cooperation in order to change the causal loop structure related to the decline of walking. Therefore, it is necessary to establish legal and institutional conditions so that multi-sectoral and multidisciplinary approaches are possible.

Optimal placement of piezoelectric actuators and sensors on a smart beam and a smart plate using multi-objective genetic algorithm

  • Nestorovic, Tamara;Trajkov, Miroslav;Garmabi, Seyedmehdi
    • Smart Structures and Systems
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    • 제15권4호
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    • pp.1041-1062
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    • 2015
  • In this paper a method of finding optimal positions for piezoelectric actuators and sensors on different structures is presented. The genetic algorithm and multi-objective genetic algorithm are selected for optimization and $H_{\infty}$ norm is defined as a cost function for the optimization process. To optimize the placement concerning the selected modes simultaneously, the multi-objective genetic algorithm is used. The optimization is investigated for two different structures: a cantilever beam and a simply supported plate. Vibrating structures are controlled in a closed loop with feedback gains, which are obtained using optimal LQ control strategy. Finally, output of a structure with optimized placement is compared with the output of the structure with an arbitrary, non-optimal placement of piezoelectric patches.