• Asian Spine Journal
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• 제12권6호
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• pp.998-1009
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• 2018

Study Design: Olfactory ensheathing cells (OECs) from rat olfactory mucosa were cultured, characterized, and transplanted into a rat model of spinal cord injury (SCI). Purpose: To evaluate different doses of OECs in a rat model of SCI. Overview of Literature: SCI causes permanent functional deficit because the central nervous system lacks the ability to perform spontaneous repair. Cell therapy strategies are being explored globally. The clinical use of human embryonic stem cell is hampered by ethical controversies. Alternatively, OECs are a promising cell source for neurotransplantation. This study aimed to evaluate the efficacy of different doses of allogenic OEC transplantation in a rat model of SCI. Methods: OECs were cultured from the olfactory mucosa of Albino Wistar rats; these cells were characterized using immunohistochemistry and flow cytometry. Rats were divided into five groups (n=6 rats each). In each group, different dosage ($2{\times}10^5$, $5{\times}10^5$, $10{\times}10^5$, and >$10{\times}10^5$) of cultured cells were transplanted into experimentally injured spinal cords of rat models. However, in the SCI group, only DMEM (Dulbecco's modified Eagle's medium) was injected. Rats were followed up upto 8 weeks post-transplantation. The outcome of transplantation was assessed using the Basso, Beattie, Bresnahan (BBB) scale; motor-evoked potential studies; and histological examination. Results: Cultured cells expressed 41% of p75NTR, a marker for OEC, and 35% of anti-fibronectin, a marker for olfactory nerve fibroblast. These cells also expressed $S100{\beta}$ and glial fibrillary acid protein of approximately 75% and 83%, respectively. All the transplanted groups showed promising BBB scores for hind-limb motor recovery compared with the SCI group (p<0.05). A motor-evoked potential study showed increased amplitude in all the treated groups compared with the SCI. Green fluorescent protein-labeled cells survived in the injured cord, suggesting their role in the transplantation-mediated repair. Transplantation of $5{\times}10^5$ cells showed the best motor outcomes among all the doses. Conclusions: OECs demonstrated a therapeutic effect in rat models with the potential for future clinical applications.

• The Journal of the Korea institute of electronic communication sciences
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• 제17권4호
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• pp.607-616
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• 2022

A new axial flux permanent magnet machine with soft magnetic composited cores is proposed for electric vehicle application in this paper. The windings and soft magnetic composited cores can be designed to form a very compact structure, and; thus, the torque density can be improved greatly. To obtain the a good flux concentrating ability, two toroidally wound internal stator machines are designed and analyzed, and the designed motor is with NdFeB magnet for high-performance electric vehicle application. The 3-D finite-element method is used to analyze the electromagnetic parameter and performance, for performance comparison, a commercial axial flux permanent magnet machine is used. The proposed motor reduced weight about 5.8%, produced torque higher than about 8Nm for existing motor.

• Therapeutic Science for Rehabilitation
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• 제3권1호
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• pp.47-55
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• 2014

Objective : The purpose of this study is to assess effects of evjenth-hamberg stretching on upper-extremity function and ADL performance ability of patient with subacute stroke patients Methods : The object of this study K-hospital located in daegu, 39-year-old man who have receiving inpatient treatment with stroke. The subject during the period of four weeks, five times a week, and thirty minutes for one session, evjenth-hamberg stretching exercise of affected side. Before and after the intervention in order to compare upper-extremity function was assessed using manual function test(MFT), motor activity log(MAL) and ADL performance ability was assessed by functional independence measure(FIM). Results : Upper-extremity function of the object score improved from each 3 in MAL, the ADL performance ability score increased from 73 to 94. Conclusion : The result of this study evjenth-hamberg stretching in patients with subacute stroke upper-extremity function and ADL performance ability to promote was found that the effect. The evjenth-hamberg stretching in the occupational therapy, if appropriately utilized more on the functional recovery of patients is expected to be helpful.

• Journal of the Korean Data and Information Science Society
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• 제22권1호
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• pp.57-64
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• 2011

The Korea Sport Talent Search System (KOSTASS) can easily assess potential of Korean youth in 23 sport events and to identify sports talents who have high potential in track-and-field, swimming and gymnastics. The purpose of present study was to analysis relationship between sports talent test scores and KOSTASS scores. Physique, physical fitness, motor ability and physiological tests including skeletal age were administrated. Data of 201 elementary students who aged 7 to 12 living in Seoul area were collected. For pure association analysis, Pearson correlation coefficient and partial correlation coefficient are used and stepwise regression analysis is used for selecting important sports talent test scores. The results show that skeletal age, weight, chest circumference, 50-meter run, and half-squat jump have relatively low impact on six KOSTASS scores. The KOSTASS program would contribute to identify talented youth in sports among Korean youth population and success for international sports competition.

• Journal of the Korean Society of Physical Medicine
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• 제5권4호
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• pp.655-666
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• 2010

Purpose : The examine the reliability and validity of the modified Emory Functional Ambulation Profile(mEFAP) for assessing gait function in chronic stroke patients. Methods : A total of 45 stroke patients, who had a stroke more than 6 months, participated in the study. Reliability was determined by Intra-class Correlation Coefficient($ICC_{3,1}$), including Bland and Altman method (Standard Error of Measurement: SEM, Small Real Differences: SRD). Validity was examined by correlating results to the gait ability(mEFAP, Modified Motor Assessment Scale-Gait(MMAS-G), Scandinavian Stroke Scale-Gait(SSS-G), Functional Ambulation Category(FAC), 10m Waking Test(10m WT)), and Fugl Meyer-Lower/Extremity(FM-L/E), Berg Balance Scale(BBS). Results : Inter-rater reliability for the total mEFAP was High($ICC_{2,1}$=.998), and absolute reliability were excellent (SEM: 1.75, SRD: 4.85). Subjects without assistance factor performed better on all tests than did subjects who had stroke. There were significant correlations between the mEFAP and MMAS-G, SSS-G, FAC(r=-.66~-.79), 10 m WT(r=-.86), and FM-L/E, BBS(r=-.72~-.78), indicating good validity. Increased times on the mEFAP correlated with poor performance on the gait ability, motor function of lower extremity, BBS and slow gait speeds on the 10 m WT in stroke patients. Conclusion : The mEFAP can be administered easily and comprehensively. It is a reliable gait assessment tool for patients with stroke and correlated with known of function, the mEFAP may be a clinically useful measure of ambulation.

• Aerospace Engineering and Technology
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• 제3권2호
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• pp.56-64
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• 2004

In this research, design results of computer hardware which control solid motor movable nozzle thrust vector control(TVC) actuator for Korea Space Launch Vehicle I(KSLV-I) are described. TVC computer hardware is the equipment which has jobs for receiving control commands from Navigation Guidance Unit(NGU) and then actuating TVC actuator. Also, it has ability to communicate with other on board or ground equipments. Computer hardware has a digital signal processor as the main processor which is capable of high speed calculating ability of control algorithm, so it can have more stability, reliability and flexibility than the previous analog controller of KSR-III. Target board was designed for on board program development and then first prototype hardware was developed. Top level system design criteria, hardware configurations and ground support equipment of TVC computer system are described.

• Physical Therapy Korea
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• 제11권1호
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• pp.1-17
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• 2004

The purposes of this study were to find correlations among Fugl-Meyer Assessment scale, gait speed, and Timed Up & Go test (TUG) and to predict gait ability from subscales of Fugl-Meyer Assessment scale. The study population consisted of 30 stroke patients referred to the Department of Rehabilitation Medicine in the Bundang Jaesang General Hospital. All subjects were ambulatory with or without an assistive device. All participants were assessed on Fugl-Meyer Assessment scale and gait speed (m/s), TUG (s). The data were analyzed using independent t-test, Pearson product moment correlation analysis and stepwise multiple regression. The results revealed that all items of Fugl-Meyer Assessment scale, except passive joint range of motion were significantly correlated with gait speed and TUG. In particular, sensation score, lower extremity motor and coordination score have a significant correlation with gait speed and TUG (p<.05). The sensation score and lower extremity motor score were important factors in comfortable gait and maximal gait speed. Their power of explanation regarding comfortable gait and maximal gait speed were 63.0% and 65.0%, respectively. The sensation score and lower extremity coordination score were important factors in TUG. Their power of explanation regarding TUG was 55.0%. These results showed that Fugl-Meyer Assessment scale is significantly correlated with gait speed and TUG. Therefore Fugl-Meyer Assessment scale is an appropriate assessment tool to predict gait ability of patients with stroke. Further study about gait speed and TUG by change of Fugl-Meyer Assessment score is needed using a longitudinal study design.

• Physical Therapy Korea
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• 제21권3호
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• pp.55-62
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• 2014

This study investigated the relationship between function classification systems and the Pediatric Evaluation of Disability Inventory (PEDI) functional skills in children with cerebral palsy (CP). Two hundred and eleven children with CP participated in this study. The Korean-Gross Motor Function Classification System (K-GMFCS), Korean-Manual Ability Classification System (K-MACS), Korean-Communication Function Classification System (K-CFCS), and self-care, mobility, and social function domains of the Korean-Pediatric Evaluation of Disability Inventory (K-PEDI) functional skills were measured by physical therapists or occupational therapists. All of the function classification systems were significantly correlated with PEDI functional skills ($r_s$=-.549 to -.826) (p<.05). Especially, K-GMFCS, K-MACS, and K-CFCS were correlated significantly with mobility, self-care, and social function, respectively. Using stepwise multiple regression analysis, we established that K-GMFCS, K-MACS, and K-CFCS were predictors of self-care skills (74.3%) and mobility skills (79.5%) of the K-PEDI (p<.05). In addition, K-CFCS and K-MACS were predictors of social function (65.9%) of the K-PEDI (p<.05). The information gathered in this study using the levels measured in the function classification systems may be useful to clinicians for estimating the PEDI functional skills in children with CP.

• Journal of The Korean Society of Integrative Medicine
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• 제9권4호
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• pp.167-181
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• 2021

Purpose : This study was conducted to investigate whether phonetic complexity affected the type and frequency of articulation errors and the acoustic duration of consonants and words produced by children with functional articulation and phonological disorders. Methods : The participants in this study were 20 children with functional articulation and phonological disorders and 20 children without such disorders who were between 3 years 7 months old and 4 years 11 months old. The participants were asked to name what they saw in pictures and their responses were recorded. The types and frequencies of articulation errors and the acoustic duration of words were analyzed and words were categorized as being of either 'high' or 'low' phonetic complexity. The acoustic duration of initial and final consonants and vowels following initial consonants were compared between the groups according to articulatory complexity. Results : Children with functional articulation and phonological disorders produced articulation errors more frequently when saying high complexity words and had longer word duration when saying low-complexity words than children without such disorders. There was no major difference in initial and final consonant duration between the groups. but the main effect of articulatory complexity on the duration of both consonants was significant. Conclusion : These results suggest that the articulatory-phonic structure of words influences the speech motor control ability of children with functional articulation and phonological disorders. When articulating consonants, children with functional articulation and phonological disorders had speech motor control ability similar to that of children without such disorders.

• Korean Journal of Cognitive Science
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• 제29권2호
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• pp.121-135
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• 2018

Dancers' motions are perceived by observers through visual processes with visual information forming the basis for the observers' appreciation and evaluation of the dancers' motions. There have been many discussions as to whether or not observers' personal athletic capabilities form an essential basis for accurate assessment of the motions of others but, so far, no valid conclusions have been reached. The purpose of this study is to investigate how the ability to predict motions of others varies depending on the athletic expertise of the observers. Participants of this research were ballet dancers of varying athletic expertise. Twenty seven participants were divided into three groups with nine in each: beginners, intermediate experts and experts. The participants watched the same dance video and then evaluated whether the motion would be successful or not. The movement related visual information required to evaluate the success of the motion was systematically adjusted by controlling the length of the video. Using the temporal occlusion method, this study measured the response accuracy of the participants by category of expertise. Under the circumstance with insufficient visual information to utilize, the experts showed higher rates of correct response than the intermediate experts and the beginners. The beginners showed higher rates of wrong response than the experts and the intermediate experts. These results showed that the ability to predict success or failure of a dance motion varied depending on motion expertise of the observers, although they had similar level of expertise in perception. Participants considered to have high athletic expertise showed high prediction ability on the result of the motion. In addition, high expertise in perception reduced the likelihood that participants would make hasty responses under the circumstance with insufficient information and helped to reduce wrong response rate. In conclusion, this study showed that motor expertise and perceptual expertise contribute to prediction accuracy of observed motions.