• Journal of Fashion Business
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• v.24 no.5
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• pp.21-34
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• 2020

The purpose of this study was to develop a new Korean fashion design using forced-relationship techniques and the traditional hanbok Korean dress and Korean traditional images as the source of the ideas. The research methods consisted of literature research and design production. In the literature research for the hanbok composition and design elements, the concept and type of forced-relationship techniques were studied. The design development process was as follows. First, 'Developing a Korean fashion design' was set as the design theme. Second, the composition and design elements of hanbok and Korean motifs, which consist of Korean images were set as fixed elements of the forced-relationship technique. Third, among the various trends in keywords, 'punk' belonging to a subculture, was set as an arbitrary element of the forced-relationship technique. Fourth, the punk fashion design elements and items were listed. Fifth, a rough sketch was performed by selectively combining fixed and arbitrary elements. Sixth, a design evaluation process was conducted to select the designs out of 52 design sketches that fit the purpose of the study. Seventh, a total of six designs were selected after making design modifications. Through this, a total of six works of women's clothing was designed, made, and presented. This study offers the possibility of developing new Korean fashion design images, and a chance to share designs based on different cultural elements in the global market.

• Bulletin of the Korean Chemical Society
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• v.33 no.8
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• pp.2508-2512
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• 2012

Cold shock proteins (CSPs) are a family of proteins induced at low temperatures. CSPs bind to single-stranded nucleic acids through the ribonucleoprotein 1 and 2 (RNP 1 and 2) binding motifs. CSPs play an essential role in cold adaptation by regulating transcription and translation via molecular chaperones. The solution nuclear magnetic resonance (NMR) or X-ray crystal structures of several CSPs from various microorganisms have been determined, but structural characteristics of psychrophilic CSPs have not been studied. Therefore, we optimized the purification process to obtain highly pure Lm-Csp and determined the three-dimensional structure model of Lm-Csp by comparative homology modeling using MODELLER on the basis of the solution NMR structure of Bs-CspB. Lm-Csp consists of a ${\beta}$-barrel structure, which includes antiparallel ${\beta}$ strands (G4-N10, F15-I18, V26-H29, A46-D50, and P58-Q64). The template protein, Bs-CspB, shares a similar ${\beta}$ sheet structure and an identical chain fold to Lm-Csp. However, the sheets in Lm-Csp were much shorter than those of Bs-CspB. The Lm-Csp side chains, E2 and R20 form a salt bridge, thus, stabilizing the Lm-Csp structure. To evaluate the contribution of this ionic interaction as well as that of the hydrophobic patch on protein stability, we investigated the secondary structures of wild type and mutant protein (W8, F15, and R20) of Lm-Csp using circular dichroism (CD) spectroscopy. The results showed that solvent-exposed aromatic side chains as well as residues participating in ionic interactions are very important for structural stability. Further studies on the three-dimensional structure and dynamics of Lm-Csp using NMR spectroscopy are required.

• Journal of the Korea Fashion and Costume Design Association
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• v.20 no.1
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• pp.151-165
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• 2018

Keith Haring is an artist from the 1980s who was highly influenced by the pop art of the 1960s, sublimating the '60s pop art into high art using cartoon images. His work contained social messages via the aesthetics of pop art. This satire seems to be intertwined with the punk style of the 1970s, as well. In this context, this thesis has developed a new "Punky-Pop Look" by integrating the art work of Keith Haring, which has both artistic value and popularity, with punk, which is a funky culture with the aim of creating something new. The purpose of this research is not directly borrow from Keith Haring's work, but to develop and apply a new fashion motif having its own unique story based on his cartoon style formativeness and creative ideas in order to further design the punky-pop look in the trend of "Hybrid Fashion." This thesis can establish a good precedent for applying the cartoon style formativeness of Keith Haring to the development of a fashion motif having its own unique story, and suggest punky-pop fashion design. Based on this thesis, new creative motifs can be generated continuously, not by simply borrowing but by developing existing art work.

• The Korean Journal of Physiology and Pharmacology
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• v.21 no.2
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• pp.197-204
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• 2017

In the present study, we tried to examine whether oleanolic acid regulates the activity, secretion and gene expression of matrix metalloproteinase-3 (MMP-3) in primary cultured rabbit articular chondrocytes, as well as the production of MMP-3 in the knee joint of rat to evaluate the potential chondroprotective effect of oleanolic acid. Rabbit articular chondrocytes were cultured in a monolayer, and reverse transcription-polymerase chain reaction (RT-PCR) was used to measure interleukin-$1{\beta}$ (IL-$1{\beta}$)-induced gene expression of MMP-3, MMP-1, MMP-13, a disintegrin and metalloproteinase with thrombospondin motifs-4 (ADAMTS-4), ADAMTS-5 and type II collagen. In rabbit articular chondrocytes, the effects of oleanolic acid on IL-$1{\beta}$-induced secretion and proteolytic activity of MMP-3 were investigated using western blot analysis and casein zymography, respectively. The effect of oleanolic acid on in vivo MMP-3 protein production was also examined, after intra-articular injection to the knee joint of rat. The results were as follows: (1) oleanolic acid inhibited the gene expression of MMP-3, MMP-1, MMP-13, ADAMTS-4, and ADAMTS-5, but increased the gene expression of type II collagen; (2) oleanolic acid reduced the secretion and proteolytic activity of MMP-3; (3) oleanolic acid suppressed the production of MMP-3 protein in vivo. These results suggest that oleanolic acid can regulate the activity, secretion and gene expression of MMP-3, by directly acting on articular chondrocytes.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.5
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• pp.2383-2388
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• 2016

Background: The reversion-inducing-cysteine-rich protein with Kazal motifs (RECK) gene is a novel transformation suppressor gene linked to several malignancies. Objective: To analyze any association between RECK gene rs10814325 single-nucleotide polymorphism (SNP) and HCC susceptibility with various clinicopathological and laboratory data. Materials and Methods: RECK gene rs10814325 SNP was estimated, using real-time PCR, in 30 HCC patients on top of HCV infection, 30 HCV related cirrhotic patients and 30 healthy controls. Results: No special pattern of association could be detected on comparing the RECK gene rs10814325 genotypes(P=0.5), or alleles(P=0.49) among the studied groups. HCC patients with TT genotype had younger age (mean of $54.1{\pm}6.0$ years vs $60.6{\pm}10.2$ years for TC/CC genotypes, P=0.035). Abdominal distension was significantly greater in TT genotype patients (75% vs 30%for TC/CC genotypes, P=0.045). The TT genotype was present in 75% of patients with lymph node metastasis. Serum GGT levels were higher in TT genotype patients [80 (48.5-134.8) IU/L vs 40 (33-87.5) IU/L for TC/CCgenotypes], and lower limb edema was observed in 60% for TT vs 20% for TC/CCgenotypes, but both just failed to reach significance (p=0.05 and p=0.06 respectively). Conclusions: RECK gene rs10814325 T>C could not be considered a risk factor for HCC development on top of HCV, but may be related to the disease progression and metastasis.

• The Research Journal of the Costume Culture
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• v.24 no.2
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• pp.180-197
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• 2016

The purpose of this study is to create knit ruffles that represent the aesthetic and artistic values of painted works of art that rhythmically express flower petals and add an artistic impression on the knit ruffle designs. This study is based on the artistic life of Georgia O'Keeffe and changes in her artistic background, and the world of paintings. The relevant data was gathered from domestic and foreign references, academic journals, and the internet. The characteristics of Georgia O'Keeffe paintings were examined. Her paintings typically include a series of various motifs, symmetry, balance, and harmony of detailed realistic expressions and abstract elements, repetition, and the principles of contrast and emphasis in shaping. The decoration techniques used on fabrics were applied using the knitting machine which controls the tension to develop a variety of textures, apart from the previous standardized knit textures, through various knitting techniques. A gradation effect was then applied by piece-dyeing the knitted materials in various colors to express asimilarity to the original colors in O'Keeffe's works with delicate color expressions. After the piece-dyeing, the decorative knitted materials were trimmed on a model to re-create the natural curves of flower petals. This study aims to converge works of art with fashion designs to develop various creative knitted fashion and to impart an artistic sense in the fashion design industry.

• Environmental Mutagens and Carcinogens
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• v.22 no.3
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• pp.137-141
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• 2002

The SNF2/SW12 family comprises proteins from a variety of species with in vivo functions, such as transcriptional regulation, maintenance of chromosome stability during mitosis, and various types of DNA repair. This study was shown the characterization of hrp2+ gene which was isolated by PCR amplification using the conserved domain of SNF2 motifs. Sequence analysis of hrp2+ gene showed striking evolutionary conservation among the SNF2 family of proteins. The transcript of hrp2+ gene was found to be a 4.7 kb as identified by Northern hybridization. In addition, to determine the transcription initiation site of hrp2+ gene, primer extension analysis was performed. This result showed the band of 64 bp. The transcriptional start point was mapped to a position of 47 base pair from the first ATG codon of translational initiation codon. In order to investigate the inducibility of hrp2+ gene, transcript levels were examined after treating the cells to various DNA damaging agents. The transcripts of hrp2+ were induced by UV-irradiation. But the transcripts were not induced by treatment of 0.25% Methylmethane sulfonate (MMS). These results implied that the effects of damaging agents are complex and different regulatory pathways exist for the induction of this gene.

• Archives of design research
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• v.13 no.3
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• pp.101-110
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• 2000

Taking a look at art history around the world reveals the presence of ceramics in a wide range of areas. There have been many changes and developments over the years, but especially notable is the fact that in the course of history, the craft of ceramics has become an aesthetic art form rather than serving the original purpose of providing daily object of necessity. The Art Nouveau movement had peat influence in the development of ceramics before and after 19$^{th}$ century, and its inherent style continues to be copied and produced to modem day. The Art Nouveau style can today be seen particularly in contemporary tableware designs reflecting its graceful motifs that are now richly presenting themselves on table settings. This study looks at the possibilites of Art Nouveau in ceramics, namely by combining both traditional formativ qualities and contemporary visual inspirations to seek new expressions of beauty. In order to document records and analyze formative developments of Art Nouveau, representative pieces have been chronologically presented to cover the period from 1895 to the present.

• Microbiology and Biotechnology Letters
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• v.36 no.3
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• pp.189-194
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• 2008

The phospholipase B (PLB) families are enzymes sharing phospholipase (PL), lysophospholipase (LPL) and lysophospholipase-transacylase (LPTA) activities. In this study, we report the putative gene encoding phospholipase B (plbA) containing lipase motifs was cloned for the first time from the filamentous fungus, Aspergillus nidulans. plbA was isolated from A. nidulans genomic DNA library using a PCR-amplified probe, which is designed on the basis of sequence information derived from the conserved lipase regions of various PLBs. The deduced product of plbA is of 626 amino acids. From the assigned sequence, PlbA showed 72% identity with Penicillium notatum PLB but have low similarity with phospholipase A of other organisms.

• Journal of the Korea Fashion and Costume Design Association
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• v.14 no.3
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• pp.195-204
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• 2012

Since WWII and the Korean War, Korean modern fashion has been americanized by claiming, displacing with, and fusing with the traits of American fashion. The purpose of this study is to observe and analyze the traits of Americanization in Korean fashion, focusing on the designs of Nora Noh fashion from the 1950s to the 1980s. Nora Noh (1928- ), one of the first Korean fashion designers, who launched the first fashion show in 1956, introduced ready-made dresses to Korean fashion industry in 1963 for the first time, and later in the 1970s and the 1980s, exported Korean-made fashions to the U.S. market. For such purpose, this study first provides the theoretical backgrounds of Americanization in Korean fashion history and then conducts a case study by analyzing photographic materials. In case of Nora Noh fashion, the traits of Americanization can be defined as functionality, popularity, and hybrid. (1)Functionality in Americanized Korean fashion was expressed through simplicity, practicality, and usefulness. Noh's "homewear" style and exported silk dresses are the examples of the functionality. (2)Popularity was shown in kitsch images of materialistic and consumer culture. It was expressed in ready-made dresses and trendy styles of mini skrits and bell-bottom pants. (3)Hybrids of various multi-culture exist in American culture and fashion. In Noh's designs, traditional materials and the print patterns inspired from traditional motifs were used to add Korean nuances in Americanized fashion.