• Korean Journal of Biological Psychiatry
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• v.17 no.4
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• pp.194-202
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• 2010

Alzheimer's disease(AD) is the most common neurodegenerative disorder and constitutes about two thirds of dementia. Despite a lot of effort to find drugs for AD worldwide, an efficient medicine that can cure AD has not come yet, which is due to the complicated pathogenic pathways and progressively degenerative properties of AD. In its early clinical phase, it is important to find the subtle alterations in synapses responsible for memory because symptoms of AD patients characteristically start with pure impairment of memory. Attempts to find the target synaptic proteins and their pathogenic pathways will be the most powerful alternative strategy for developing AD medicine. Here we review recent progress in deciphering the role of target synaptic proteins related to AD in hippocampal glutamatergic synapses.

• The Bulletin of The Korean Astronomical Society
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• v.37 no.2
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• pp.63-63
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• 2012

The Square Kilometre Array (SKA) will be the world's largest and most sensitive radio telescope. It will address a wide range of fundamental questions in physics, astrophysics, cosmology and astrobiology. Australia, one of the two countries selected to host the SKA, has spent several years preparing by opening up the Murchison Radio-astronomy Observatory (MRO) as a uniquely radio quiet site in Western Australia, and by constructing the world's most powerful radio survey telescope, the Australian SKA Pathfinder (ASKAP). The SKA will be built in two phases. Phase I will include ASKAP, which will use novel phased-array feeds and grow to become "SKA-survey". Phase I will also include a dish array ("SKA-mid") in South Africa and a low-frequency array ("SKA-low") in Australia, and is slated for operation from about 2020. Phase II of the SKA will consist of further expansion of SKA-low and SKA-mid and is due for completion in the middle of the next decade.

• STI Policy Review
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• v.8 no.2
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• pp.94-109
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• 2017

Entrepreneurship is a creation of new combinations of goods and services. Today, every aspect of business operations has been changing, which we call development. The conventional business included production and manufacturing of goods and serving things the customer needed. Today, the business has changed form so that the demands of customers are shaped by the good or service which has been created by the businesses. Entrepreneurship in Mongolia is not a new concept but nowadays the number of entrepreneurs in Mongolia has grown sharply. Mongolia was a nomadic culture during its history and is probably the only nomadic culture left in the world today. Mongolian herders are the largest and the most powerful representation of successful entrepreneurs in Mongolia. Another practice of herders in the world are in Australia. Along with a comparison of the policy and government support system of Australia, this study intends to assess how 6 factors of the entrepreneurial ecosystem fit herders in Mongolia. As a result of this assessment, we propose policy to support the entrepreneurial mechanism of herders and identify cultural factors which support the existence of herding.

• Journal of the Korean Magnetic Resonance Society
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• v.22 no.4
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• pp.101-106
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• 2018

Magnetite is the oldest magnet material known to mankind. It is getting attention again from solid state physics researchers now a days because it is one of the most strongly correlated electron systems. Spin, charge, and orbital orders are interplaying with lattice and involved in the Verwey transition where magnetization, conductivity, and structure changes suddenly. The peculiar ordering states above and below the transition temperature mainly originate from the coexistence of $Fe^{2+}$ and $Fe^{3+}$ ions in the B site of the inverse spinel structure. In particular, the state of the charge and orbital order was the oldest and most intriguing problem. NMR has made significant contribution to the investigation of this question. A. Abragam stated that there is no doubt that NMR is a very powerful tool for the study of ferromagnetic and antiferromagnetic materials. In this mini-review, a short history of NMR investigation of magnetite is presented, providing a support to Abragam's claim.

• Journal of the Korean Home Economics Association
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• v.44 no.2 s.216
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• pp.137-152
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• 2006

The major purpose of this study was to investigate the causal effect of the primary triad experiences on dating relationship satisfaction through self-esteem among college students. The primary triad experiences were composed of the parents' differentiation level of couple relationship and the parent-child relationship including family rule, triangulation and communication. Dating relationship satisfaction included such subscales as problem-solving communication, global satisfaction, affection communication and time together. The study data were collected from 382 college students by using self-administered questionnaire method. The results showed that parents' differentiation was positively correlated with self-esteem and all components of dating relationship satisfaction and that family rule was negatively associated only with problem-solving communication. Triangulation was negatively related with most components of dating relationship satisfaction and self-esteem, while parent-child communication showed positive correlations with the same variables. Path analysis results showed that self-esteem mediated the effect of most variables of primary triad experiences on dating relationship satisfaction. In addition, variables of the primary triad experience had direct influences on most components of dating relationship satisfaction. Self-esteem was found to be the most powerful variable influencing dating relationship satisfaction. The findings of the study were discussed in terms of pre-marital education and counseling.

• Mycobiology
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• v.38 no.4
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• pp.229-237
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• 2010

Members of the genus Aspergillus are the most common fungi and all reproduce asexually by forming long chains of conidiospores (or conidia). The impact of various Aspergillus species on humans ranges from beneficial to harmful. For example, several species including Aspergillus oryzae and Aspergillus niger are used in industry for enzyme production and food processing. In contrast, Aspergillus flavus produce the most potent naturally present carcinogen aflatoxins, which contaminate various plant- and animal-based foods. Importantly, the opportunistic human pathogen Aspergillus fumigatus has become the most prevalent airborne fungal pathogen in developed countries, causing invasive aspergillosis in immunocompromised patients with a high mortality rate. A. fumigatus produces a massive number of small hydrophobic conidia as the primarymeans of dispersal, survival, genome-protection, and infecting hosts. Large-scale genome-wide expression studies can now be conducted due to completion of A. fumigatus genome sequencing. However, genomics becomes more powerful and informative when combined with genetics. We have been investigating the mechanisms underlying the regulation of asexual development (conidiation) and gliotoxin biosynthesis in A. fumigatus, primarily focusing on a characterization of key developmental regulators identified in the model fungus Aspergillus nidulans. In this review, I will summarize our current understanding of how conidiation in two aspergilli is regulated.

• Journal of Information Technology Services
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• v.16 no.4
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• pp.161-176
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• 2017

Recently, most of the users can easily get access to a variety of information sources about companies, products, and services through online channels. Therefore, the online user evaluations are becoming the most powerful tool to generate word of mouth. The user's evaluation is provided in two forms, quantitative rating and review text. The rating is then divided into an overall rating and a detailed rating according to various evaluation criteria. However, since it is a burden for the reviewer to complete all required ratings for each evaluation criteria, so most of the sites requested only mandatory inputs for overall rating and optional inputs for other evaluation criteria. In fact, many users input only the ratings for some of the evaluation criteria and the percentage of missed ratings for each criteria is about 40%. As these missed ratings are the missing values in each criteria, the simple average calculation by ignoring the average 40% of the missed ratings can sufficiently distort the actual phenomenon. Therefore, in this study, we propose a methodology to predict the rating for the missed values of each criteria by analyzing user's evaluation information included the overall rating and text review for each criteria. The experiments were conducted on 207,968 evaluations collected from the actual hotel evaluation site. As a result, it was confirmed that the prediction accuracy of the detailed criteria ratings by the proposed methodology was much higher than the existing average-based method.

• Journal of Korean Society of Rural Planning
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• v.22 no.2
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• pp.9-18
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• 2016

In this research, we reappraise saemaul project which is a leading role of rural development in a present perspectives and deduct social and political implications for rural development. For deducting problems and implications, related documents and previous researches are reviewed. Administration statistics are also gathered and analyzed for monitoring detailed projects propulsion progress and results. Samaul project is reappraised based on previous researches such as rural development, regional agricultural production system improvement, agricultural distribution system improvement, leader breeding, income improvement, and governance. Saemaul project has basically positive characteristics because of decreasing growth gap of urban and rural area by empowering cooperation of rural residents, instilling leadership, making village fund, constricting networks of government and urban area for administrative and financial assistant. In conclusion, there are implications that continues interests of most powerful sovereignty and comprehensive assistant of government are needed for overcome agricultural and rural crisis. Saemaulundong is a united and systematic approach in village level. In south korea where most of farms are small size, village or regional level assistants started in saemaulundong are still needed. In regional development, we can infer that will and ability development of participated residents are most basic and important factors for successful project propulsion in saemaul project.

• Journal of Family Relations
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• v.22 no.2
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• pp.27-50
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• 2017

Objectives: This study explored the effect of adolescents' sociodemographic variables, parenting rearing styles, resilience, and life satisfaction on adolescents' depression. The resilience as mediating effects of parental rearing styles and life satisfaction on depression was examined as well. Method: The data were from 2,108 middle school freshmen panel of a national sample at the forth year, Korea Children and Youth Panel Survey(KCYPS). Hierarchical multiple regressions and mediation regression analyses, steps for testing mediation by Baron and Kenny, were conducted. Results: Adolescents' resilience had both direct and mediating significant effects, showing that resilience partially mediated the effects of affective parental rearing style and life satisfaction on depression, respectively. Life satisfaction had the most significant impact on adolescents' depression. Conclusions: While some parental rearing styles were significant, adolescents' personal properties including resilience and life satisfaction revealed the most significant explanatory power of adolescents' depression. Life satisfaction was the most powerful predictor for lessening adolescents' depression.

• Journal of Korea Multimedia Society
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• v.25 no.8
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• pp.1233-1241
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• 2022

Tumors of the brain are the deadliest, with a life expectancy of only a few years for those with the most advanced forms. Diagnosing a brain tumor is critical to developing a treatment plan to help patients with the disease live longer. A misdiagnosis of brain tumors will lead to incorrect medical treatment, decreasing a patient's chance of survival. Radiologists classify brain tumors via biopsy, which takes a long time. As a result, the doctor will need an automatic classification system to identify brain tumors. Image classification is one application of the deep learning method in computer vision. One of the deep learning's most powerful algorithms is the convolutional neural network (CNN). This paper will introduce a novel deep learning structure and image gradient to classify brain tumors. Meningioma, glioma, and pituitary tumors are the three most popular forms of brain cancer represented in the Figshare dataset, which contains 3,064 T1-weighted brain images from 233 patients. According to the numerical results, our method is more accurate than other approaches.