• Title/Summary/Keyword: morphological transition

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Electrical Conductivity of Carbon Fiber-Polymer Composite (Carbon 화이버-폴리머 복합체의 전기적 특성)

  • 이재연;최경만
    • Journal of the Korean Ceramic Society
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    • v.35 no.6
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    • pp.603-609
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    • 1998
  • The composites of insulating polymer filled with conducting carbon-fiber were fabricated by molding press method. To understand the fiber aspect-ratio dependence of electrical conductivity the aspect ratio was varied from 4 to 10 The percolation thresholds of transition from the insulator to the conductor de-creased as the fiber aspect ratio increased. The percolation threshold of fiber-segregated composite in this study was smaller than that of fiber-random composite shown in other study. When the electrical con-ductivity curves were fitted by general effective medium equation morphological variable(t) decreased as the fiber aspect-ratio increased.

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DETERMINATION OF PHYSICAL QUANTITIES OF GLOBULAR CLUSTERS

  • Kim, Kang-Min;Lee, See-Woo
    • Journal of The Korean Astronomical Society
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    • v.22 no.2
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    • pp.81-99
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    • 1989
  • Applying five morphological parameters defined along the main sequence (MS), red giant branch (RGB) and horizontal branch (HB) in the C-M diagram (CMD), and the transition period-luminosity relation for RR Lyrae variables, some basic physical quantities such as helium abundance, age, mass and luminosity are determined for 21 well observed globular clusters with combination of evolutionary models and atmospheric models properly chosen by the numerical test. The dependences of these quantities on the age and chemical abundance are investigated.

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Morphological Interpretation of the Transformation Process of Urban Form in Gosan-Up (형태학적 개념을 활용한 조선시대 고산현의 도시형태 변천과정 해석)

  • Lee, Kyung-Chan;Kang, In-Ae
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.32 no.4
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    • pp.37-49
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    • 2014
  • This paper aims to interpret the transformation process of town plan of Gosan-up(高山), which was provincial administrative focus town in Josun dynasty, basing on morphological viewpoint. Morphological concepts, such as morphological frame, urban plan, kernel, colonization, route system, fixation line, fringe belt, plan unit & plan division, morphological period derived from the study of Conzen, M.R.G. and Caniggia, G. epidome district, break point, broken plot, urban fallow, privatization are adopted for the interpretation of urban form. Morphological period of Gosan can be divided in four ; formation of kernel & morphological structure, disintegration & redevelopment of the kernel, augmentative development of the kernel & formation of modern epidome district, outwards expanding of urbanized area, transition & reorganization of epidome district. Especially public leading projects such as construction of new regional connection road and public facilities such as myeon(township) office, agricultural cooperatives federation office, market, are main factors of morphological transformation of townplan. In the early stage, under the Japanese imperialism, construction of the new matrix route(Gosan-ro) through the kernel and followed planned routes gave way to disintegrating traditional areal plan unit and forming small block plan units in administrative facilities area. And linear plan units with commercial buildings were formed along the new matrix route and planned route adjacent to periodical market. In the latter stage, with development of public facilities, private sectors' large circulation institution and terminal outside the kernel with planned routes formed areal block based plan units with commercial and public buildings. And part of the spatial area with the linear plan unit were turned into urban fallow. With the transformation of town plan, new roads outside the kernel have substituted for traditional fixation line of waterway with road and topographical feature. Fringe belts were made successively along the new road and around the major intersections outside of existing urbanized area. Land use in fringe belts, constituting of outer locational tendency early on formation, was gradually replaced with commercial & business buildings.

Disruption of the Dual Specificity Kinase Gene Causes the Reduction of Virulence in Candida albicans (이중특이성 인산화 효소의 결손이 Candida albicans 병원성에 미치는 효과)

  • Park, Yun-Hee;Park, Hee-Moon
    • The Korean Journal of Mycology
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    • v.39 no.1
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    • pp.85-87
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    • 2011
  • The opportunistic human pathogen Candida albicans has the ability to convert from yeast-form to pseudohyphal or true hyphal form. The morphological transition is considered as an important virulence factor, because the decrease or lack in dimorphism causes the reduction of virulence. Our previous study revealed that the disruption of dual specificity kinase gene caused the reduction of dimorphism in C. albicans. Therefore we tested the effect of dual specificity kinase in virulence using mouse model. The mean survival time for kinase-defective strains was about 15 days in comparison with those of wild-type, 3.9 days. Moreover the fungal burden on kidneys for kinase-defective strains was decreased by ten-fold than that for wild-type. These results suggest possible involvement of dual specificity kinase in a novel signal transduction pathway for morphological transition and virulence of C. albicans.

Correlation of morphological changes of rice starch granules with rheological properties during heating In excess water (가열 조리시 쌀 전분 입자들의 형태학적 변화와 리올로지 특성과의 관계)

  • Lee, Young-Eun;Osman, Elizabeth M.
    • Applied Biological Chemistry
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    • v.34 no.4
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    • pp.379-385
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    • 1991
  • Morphological changes of starch granules from 12 different varieties of rice were examined by scanning electron microscopy during heating at 2.5% (w/v) concentration. Rice starch granules proceeded through a similar pattern of progressive morphological changes daring heating, regardless of variety. Rice starch granules began to swell radially in the initial stage of gelatinization and then undergo radial contraction and random tangential expansion to form complex structures in the latter stage of gelatinization temperature range. At higher temperatures, starch granules softened and melted into thin flat discs, and then stretched into thin filaments to form three-dimensional networks. These progressive morphological changes were reflected in the changes of swelling power, solubility and amylograph viscosity of starch. During the transition of melting or softening, swelling power, solubility and amylograph viscosity increased rapidly. The time of loss of granular structure of starch depended on gelatinization temperature range. The ratio of amylose to amylopectin was largely responsible fur the rate of melting or softening and the fineness of a three-dimensional filamentous network above the gelatinization temperature range. Therefore, both the gelatinization temperature range and amylose content of starch affect the rate of cooking, and amylose content of starch affects the final texture of cooked starch paste.

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Induced Morphological Changes in Larval Rock Bream, Oplegnathus fasciatus, under Starvation

  • Park, In-Seok;Choi, Hee-Jung;Noh, Choong-Hwan;Myoung, Jung-Goo;Park, Hye Jung;Goo, In Bon
    • Development and Reproduction
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    • v.17 no.4
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    • pp.399-407
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    • 2013
  • Morphological changes in the reared rock bream, Oplegnathus fasciatus, from hatching to six days after hatching were examined during the early growth stage under starvation. All the larvae died within five days when feeding was delayed for three days after hatching. These results imply that initial larval food should be supplied within two days of hatching. Changes in the pectoral angle and the ratios of eye height to head height, gut height to standard length, and gut height to myotome height in the rock bream are alternative indicators for the identification of starving fish. These indicators might prove useful in evaluating the successful transition from endogenous to exogenous feeding in this species.

GST2 is Required for Nitrogen Starvation-Induced Filamentous Growth in Candida albicans

  • Lee, So-Hyoung;Chung, Soon-Chun;Shin, Jongheon;Oh, Ki-Bong
    • Journal of Microbiology and Biotechnology
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    • v.24 no.9
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    • pp.1207-1215
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    • 2014
  • Candida albicans, the major human fungal pathogen, undergoes morphological transition from the budding yeast form to filamentous growth in response to nitrogen starvation. In this study, we identified a new function of GST2, whose expression was required for filamentous growth of C. albicans under nitrogen-limiting conditions. The Gst2p showed Gst activity and required response to oxidative stress. The ${\Delta}gst2$ mutant displayed predominantly yeast phase growth in low ammonium media. Such morphological defect of ${\Delta}gst2$ mutants was not rescued by overexpression of Mep2p, Cph1p, or Efg1p, but was rescued by either overexpression of a hyperactive $RAS1^{G13V}$ allele or through exogenous addition of cyclic AMP. In addition, the ${\Delta}gst2$ mutants had lower levels of RAS1 transcripts than wild-type cells under conditions of nitrogen starvation. These results were consistent with the Ras1-cAMP pathway as a possible downstream target of Gst2p. These findings suggest that Gst2p is a significant component of nitrogen starvation-induced filamentation in C. albicans.

Morphology and Thermal Properties of PPS/ABS Blends (PPS/ABS 블렌드의 형태학적/열적 특성)

  • 이영관;김준명;남재도;박찬석;장승필
    • Polymer(Korea)
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    • v.24 no.3
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    • pp.366-373
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    • 2000
  • In this study, the PPS/ABS blend system was investigated in order to collectively identify the relationship among blend morphology, chemical compatibilization and thermal property. ABS resin was chemically modified by the incorporation of maleic anhydride through reactive extrusion for enhanced compatibilization, and PPS, ABS and the modified ABS were blend by a sing twin screw extruder. The effect of chemical modification of ABS on the morphological, mechanical, and thermal properities of the resulting blend was examined. A strong interaction was observed between PPS and MABS by optical microsopy as well as scanning electron microscopy, exhibiting a well-dispersed morphological feature. The PPS/MABS blend showing a single glass transition temperature was observed in dynamic mechanical analysis, demonstrating a pseudo-homogeneous phase morphology induced by chemical compatibilization. PPS/MABS blend also exhibited an enhanced thermal stability and heat distortion temperature compared with modified PPS/ABS blend.

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Protective Effect of Right Ventricular Mitochondrial Damage by Cyclosporine A in Monocrotaline-induced Pulmonary Hypertension

  • Lee, Dong Seok;Jung, Yong Wook
    • Korean Circulation Journal
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    • v.48 no.12
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    • pp.1135-1144
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    • 2018
  • Background and Objectives: Mitochondria play a key role in the pathophysiology of heart failure and mitochondrial permeability transition pore (MPTP) play a critical role in cell death and a critical target for cardioprotection. The aim of this study was to evaluate the protective effects of cyclosporine A (CsA), one of MPTP blockers, and morphological changes of mitochondria and MPTP related proteins in monocrotaline (MCT) induced pulmonary arterial hypertension (PAH). Methods: Eight weeks old Sprague-Dawley rats were randomized to control, MCT (60 mg/kg) and MCT plus CsA (10 mg/kg/day) treatment groups. Four weeks later, right ventricular hypertrophy (RVH) and morphological changes of right ventricle (RV) were done. Western blot and reverse transcription polymerase chain reaction (RT-PCR) for MPTP related protein were performed. Results: In electron microscopy, CsA treatment prevented MCT-induced mitochondrial disruption of RV. RVH was significantly increased in MCT group compared to that of the controls but RVH was more increased with CsA treatment. Thickened medial wall thickness of pulmonary arteriole in PAH was not changed after CsA treatment. In western blot, caspase-3 was significantly increased in MCT group, and was attenuated in CsA treatment. There were no significant differences in voltage-dependent anion channel, adenine nucleotide translocator 1 and cyclophilin D expression in western blot and RT-PCR between the 3 groups. Conclusions: CsA reduces MCT induced RV mitochondrial damage. Although, MPTP blocking does not reverse pulmonary pathology, it may reduce RV dysfunction in PAH. The results suggest that it could serve as an adjunctive therapy to PAH treatment.

Effect of the hedgehog signaling pathway on hair formation-related cells

  • Park, Jaehyun;Park, Sangkyu;Seo, Jeongmin;Roh, Sangho
    • International Journal of Oral Biology
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    • v.44 no.4
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    • pp.144-151
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    • 2019
  • Alopecia has emerged as one of the biggest interests in modern society. Many studies have focused on the treatment of alopecia, such as transplantation of hair follicles or inhibition of the androgen pathway. Hair growth is achieved through proper proliferation of the components such as keratinocytes and dermal papilla cells (DPCs), movement, and interaction between the two cells. The present study examined the effect of the hedgehog (Hh) signaling pathway, which is an important and fundamental signal in the cell, on the morphology and the viability of human keratinocytes and DPCs. Upregulation of Hh signaling caused a morphological change and an increase in epithelium-mesenchymal transition-related gene expression but reduced the viability of keratinocytes, while the alteration of Hh signaling did not cause any change in DPCs. The results show the possibility that the regulation of Hh signaling can be applied for the treatment of alopecia.