• Proceedings of the PSK Conference
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• 2000.04a
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• pp.129.2-129.2
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• 2000

• Proceedings of the PSK Conference
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• 2001.04a
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• pp.149.1-149.1
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• 2001

• Proceedings of the Korea Contents Association Conference
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• 2009.05a
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• pp.235-238
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• 2009

The character design is part of a culture. That is, it is not just an object but it reflects the cultural tendency and context where it is visualized. It's potential as a cultural medium of communication become pervasive in the field. One of good sources of characters is the classics which represent the nation's culture and history. The topic of this presentation is to show how a character in the Buddhist story, the Monkey King, designed differently in different context. For the purpose, the animation on the Monkey King in China, Japan and Korea are reviewed and analyzed. The result shows that the same animation character has been designed in different way in different context and it reflects the cultural tendency of the country. For example, Koreans tend to emphasize the global feature of the character. In case of Chinese, however, the character designer emphasizes traditional value. Finally, the designer in Japan tries to put their cultural element in detailed part of the character that makes it appeal to the public.

• Molecular & Cellular Toxicology
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• v.4 no.4
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• pp.323-330
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• 2008

Surrogate tissue analysis incorporating -omics technologies has emerged as a potential alternative method for evaluating toxic effect of the tissues which are not accessible for sampling. Among the recent applications, blood including whole blood, peripheral blood lymphocytes and peripheral blood mononuclear cells (PBMCs) was suggested as a suitable surrogate tissue in determining toxicant exposure and effect at the pre- or early clinical stage. In this application, we investigated transcriptomic profiles in astemizole treated Cynomolgus monkey's PBMCs. PBMCs were isolated from 4-6 years old male monkeys at 24 hr after administration45 Helvetica Light (10 mg/kg, 30 mg/kg). Gene expression profiles of astemizole treated monkey's PBMCs were determined using Affymetrix $GeneChip^{(R)}$ Human Genome U133 plus 2.0 arrays. The expression levels of 724 probe sets were significantly altered in PBMCs at 10 or 30 mg/kg after astemizole administration following determination of paired t-test using statistical criteria of ${\geq}$$1.5-fold changes at P<0.05. Gene expression patterns in PBMCs showed a considerable difference between astemizole 10 and 30 mg/kg administration groups in spite of an administration of the same chemical. However, close examination using Ingenuity Pathway Analysis (IPA) software revealed that several gene sets related to cardiotoxicity were deregulated at astemizole 10 and 30 mg/kg administration groups. The deregulation of cardiac hypertrophy related genes such as TXN, GNAQ, and MAP3K5 was observed at 10 mg/kg group. In astemizole 30 mg/kg group, genes involved in cardiotoxicity including cardiac necrosis/cell death, dilation, fibrosis, and hypertrophy were also identified. These results suggest that toxicogenomic approach using PBMCs as surrogate tissues will contribute to assess toxicant exposures and identify biomarkers at the pre-clinical stage.

• Journal of Physiology & Pathology in Korean Medicine
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• v.26 no.1
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• pp.1-9
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• 2012

Five mimic-animal boxing(五禽戱, FAB) is physical fitness exercises conducted by imitating the motions of tiger, deer, bear, monkey, and bird, devised by the famous doctor Hwa-Ta(華陀) in the Three Kingdoms of China. FAB is one of bionic-physical and breathing exercises(傍生導引) by combined automassage as a practice for health care. Although FAB have effects of health control and medical treatment, but interrelationship of five animals(五禽) of FAB and five viscera(五臟) of five elements(五行) is complicated. So, the present was designed to investigate the progress of FAB, movement-feature of FAB, and the interrelationship of five animals and five viscera. further I will develop value by sports-treatment medicine in oriental medicine. The results were as follows ; FAB is physical exercises of dynamic exercises and new-dynamic exercises. Feature of China-FAB have each movement by imitating the motions of each animals, movements of Formosa-FAB were mixed. In philosophical viewpoint, Five animals (tiger, deer, bear, monkey, bird) were attached to metal, wood, water, earth, fire of five elements, and lung, liver, kidney, spleen, heart of five viscera. In viewpoint of breathing exercises, Five animals (tiger, deer, bear, monkey, bird) were attached to water, wood, earth, fire, metal of five elements, and kidney, liver, spleen, heart, lung of five viscera. Although FAB have effects of health control and medical treatment, FAB have indication and contraindication. Therefore, I think that mechanism of treatment should reason with Oriental medicine doctor in FAB.

• Journal of the korean veterinary medical association
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• v.20 no.12
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• pp.762-764
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• 1984

Cytoplasmic inclusion bodies are observed by light microscopy in the epithelial cells of three livers and one corpus luteum from among the six rhesus monkeys available for this study. The various-sized inclusions are homogeneous, acidophilic, round to ova

• Proceedings of the Korea Society of Environmental Toocicology Conference
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• 2000.12a
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• pp.79-79
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• 2000

• Proceedings of the PSK Conference
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• 2002.04a
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• pp.167.1-167.1
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• 2002

• Journal of Life Science
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• v.10 no.1
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• pp.37-39
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• 2000

Testis-specific protein Y(TSPY) is thought to play an important role during spermatogenesis in primates. The Arg and Lys-rich region of TSPY was implicated as a potential DNA binding site in the human and Japanese monkey. In the study, we investigated this further through looking at the putative amino acid sequences of Arg and Lys-rich region of TSPY gene from seven species of gibbons, five species of Old World monkeys and five species of New World monkeys. A comparison with those of the human and Japanese monkey revealed that the Arg and Lys-rich motif was hightly conserved in various primates. This finding suggests that a possible role for the Arg and Lys-rich motif in primate TSPY is DNA recognition. The functional implications for TSPY are discussed in the light of this and previous findings.

• Animal cells and systems
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• v.7 no.4
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• pp.317-325
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• 2003

Corticostriatal connections of auditory areas within the rostral and caudal portions of the superior temporal gyrus (STG) and in the supratemporal plane(STP) of pigtail macaque (Macacca nemestrina) were studied with particular emphasis on specific projections to the ventral striatum. Retrograde tracers were Injected into five different regions of the ventral striatum such as the ventromedial caudate nucleus, ventral shell, central shell, dorsal core of the nucleus accumbens (NA), and ventrolateral putamen to Identify the cells of origin. There were only few projections from the auditory areas in the STP to the ventral striatum. However, the association (or belt) areas of the STG collectively had widespread corticostriatal projections characterized by differential topographic distributions. The rostral parts of the STG strongly projected to the ventromedial caudate nucleus. The midportion of the STG also projected to the same ventral striatal regions, but the connections were relatively less extensive. Interestingly, the caudal portion of the STG had no connection to all subregions of the ventral striatum. These differential patterns of corticostriatal connectivity suggest that the ventromedial caudate nucleus would be a major auditory convergence area and mainly involved in sound recognition rather than spatial localization of sound sources.