• Title/Summary/Keyword: molecular computer

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Deposition Ratio of Stearic Acid Lagmuir-Blodgett (LB) Films (Stearic Acid Langmuir-Blodgett (LB) 막의 누적비)

  • Choi, Yong-Sung;Lee, Dae-Il;Kwon, Young-Soo;Hong, Eon-Sik;Kang, Dou-Yol
    • Proceedings of the KIEE Conference
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    • 1991.07a
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    • pp.244-246
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    • 1991
  • Recently, a study on LB ultra thin film of molecular size is widely performed. To make use of LB ultra thin film in engineering applications, it is important to investigate how uniformly Langmuir film is deposited on a substrate. In this paper, to confirm the uniformity of film deposition, the relation between the monolayer numbers deposited and its ratio is investigated by deposition of the Y type and Hetero type LB film. If films are deposited ideally, the deposition ratio will become 1.0. From the experimental results, it can be suggested that the deposition of LB film is done well, as we obtained an approximate value 1.0 by the calculation of deposition ratio of L film area and LB film deposition area.

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Characterization of ORF39 from Helicoverpa armigera Single-nucleocapsid Nucleopolyhedrovirus, the Gene Containing RNA Recognition Motif

  • Xu, Hai-Jun;Liu, Yan-He;Yang, Zhang-Nv;Zhang, Chuan-Xi
    • BMB Reports
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    • v.39 no.3
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    • pp.263-269
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    • 2006
  • In the genome of Helicoverpa armigera single-nucleocapsid nucleopolyhedrovirus, open reading frame 39 (Ha39) is the only gene predicted to encode an RNA recognition protein. Computer analysis revealed that Ha39 homologues were found in 15 NPVs, but not in GVs. Its transcripts were detected from 3 through 72 hours post infection (h p.i.) using RT-PCR and Northern blot analysis. The protein was detected in infected-cell lysates from 6 h p.i. Western blot assay of ODV and BV preparations revealed that Ha39 encodes a structural protein associated with BVs. Additionally, immunofluorescence microscopy demonstrated that the protein was present within cytoplasm in virus-infected cells, but not in the nuclear region.

A Study on the Manufacturing Technology Development of High Purity NanoPowder (고순도 나노분말 제조기술 개발에 관한 연구)

  • 박영문;차용훈;성백섭;윤길하
    • Proceedings of the Korean Society of Precision Engineering Conference
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    • 2003.06a
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    • pp.1178-1181
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    • 2003
  • Nanotechnology is the creation and utilization of materials, devices, and systems through the control of matter on the nanometer-length scale, that is, at the level of atoms, molecules, and supramolecular structures. The essence of nanotechnology is the ability to work at these levels to generate larger structures with fundamentally new molecular organization. These nanostructures, made with building blocks understood from first principles, are the smallest human-made objects, and they exhibit novel physical, chemical, and biological properties and phenomena. The aim of nanotechnology is to learn to exploit these properties and efficiently manufacture and employ the structures. Control of matter on the nanoscale already plays an important role in scientific disciplines as diverse as physics, chemistry, materials science, biology, medicine, engineering, and computer simulation. This paper describes the superprecision nano separator to productive particle size of nano powder. this separator system is very important in the industrial area for other high technology parts.

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A Study on the Development of the Superprecision Nano Separator (초정밀 나노 분급기 개발에 관한 연구)

  • 성백섭;윤길하;차용훈
    • Proceedings of the Korean Society of Machine Tool Engineers Conference
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    • 2003.04a
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    • pp.27-32
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    • 2003
  • Nanotechnology is the creation and utilization of materials, devices, and systems through the control of matter on the nanometer-length scale, that is, at the level of atoms, molecules, and supramolecular structures. The essence of nanotechnology is the ability to work at these levels to generate larger structures with fundamentally new molecular organization. These nanostructures, made with building blocks understood from first principles, are the smallest human-made objects, and they exhibit novel physical, chemical, and biological properties and phenomena. The aim of nanotechnology is to loam to exploit these properties and efficiently manufacture and employ the structures. Control of matter on the nanoscale already plays an important role in scientific disciplines as diverse as physics, chemistry, materials science, biology, medicine, engineering, and computer simulation. This paper describes the superprecision nano separator to productive particle size of nano powder. this separator system is very important in the industrial area for other high technology parts.

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Knowledge-based synthesis system for injection molding (사출성형 제품의 지식형 설계시스템 연구)

  • 김상국
    • 제어로봇시스템학회:학술대회논문집
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    • 1986.10a
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    • pp.431-436
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    • 1986
  • The design and manufacture of injection molded polymeic parts with desired mechanical properties is a costly process dominated by empiricism, including the modification of actual tooling. This paper presents an interactive computer-based design system for injection molded plastic parts. This knowledge-based synthesis system provides a rational design strategy for injection molding and molded parts. It synergistically combines a rule-based expert system for hurestic knowledge with analytical process simulation programs. The theremomechanical properties of a molded part such as the effect of molecular orientation and weldline strength are predicted by the analysis programs; while the expert system interprets the analytical results from the process simulation, evaluates the design, and generates recommendations for optimal design alternatives. The heuristic knowledge of injection molding is formalized as production rules of the expert consultation system.

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The Study of Optimum Design of Y-Channel Micro-Mixer by Using LIF Conforcal Microscope (LIF Conforcal Microscope을 이용한 Y-channel 마이크로믹서의 최적설계 연구)

  • Kim, Sang-Woo;Hyun, Seok-Ho;Shin, Tae-Seok;Lee, Do-Hyung
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.33 no.5
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    • pp.311-317
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    • 2009
  • Due to extremely small device size and velocity scale, mixing in microchannel take place very slowly by way of molecular diffusion transport. Mixing enhancement becomes a central issue in microfluidics for biomedical and chemical applications. In this work, The optimization results and validation through experiment and fabrication. In this efficient micromixer design, it is essential to evaluate mixing efficiency with good precision. Mixing efficiency for Y-channel micromixer is measured by fluorescence intensity using LIF(Laser Induced Fluorescence) Confocal Microscope. The Y-channel micromixers are fabricated with polydimethylsiloxane(PDMS). Nile Blue A is injected into the micromixer as a fluorescence dye for measuring of fluorescence intensity by He/Ne laser. Throughout the experiments and computer simulation, accurate mixing efficiency evaluation process for a PDMS Y-channel micromixer is established.

Animal Breeding: What Does the Future Hold?

  • Eisen, E.J.
    • Asian-Australasian Journal of Animal Sciences
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    • v.20 no.3
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    • pp.453-460
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    • 2007
  • An overview of developments important in the future of animal breeding is discussed. Examples from the application of quantitative genetic principles to selection in chickens and mice are given. Lessons to be learned from these species are that selection for production traits in livestock must also consider selection for reproduction and other fitness-related traits and inbreeding should be minimized. Short-term selection benefits of best linear unbiased predictor methodology must be weighed against long-term risks of increased rate of inbreeding. Different options have been developed to minimize inbreeding rates while maximizing selection response. Development of molecular genetic methods to search for quantitative trait loci provides the opportunity for incorporating marker-assisted selection and introgression as new tools for increasing efficiency of genetic improvement. Theoretical and computer simulation studies indicate that these methods hold great promise once genotyping costs are reduced to make the technology economically feasible. Cloning and transgenesis are not likely to contribute significantly to genetic improvement of livestock production in the near future.

An effcient algorithm for multiple sequence alignment (복수 염기서열 정렬을 위한 한 유용성 알고리즘)

  • Kim, Jin;Song, Min-Dong
    • Proceedings of the Korean Information Science Society Conference
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    • 1998.10c
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    • pp.51-53
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    • 1998
  • 3개 이상의 DNA 혹은 단백질의 염기서열을 정렬하는 복수 염기서열 정렬(multiple sequence alignment)방법은 염기서열들 사이의 진화관계, gene regulation, 단백질의 구조와 기능에 관한 연구에 필수적인 도구이다. 복수 염기서열 정렬문제는 NP-complete 문제군에 속하며, 이 문제를 해결하기 위하여 가장 유용하게 사용되는 알고리즘으로는 dynamic programming이 있다. Dynamic programming은 주어진 입력 염기서열 군들에 대한 최적의 정렬을 생산할 수 있다. 그러나 dynamic programming의 단점은 오랜 실행시간이 요구되며, 때로는 dynamic programming의 속성 때문에 이 알고리즘을 사용하여도 주어진 입력 염기서열 군들에 대한 최적의 정렬을 얻어내지 못하는 경우가 있다. 본 연구에서는 이러한 dynamic programming의 문제를 해결하기 위하여 genetic algorithm을 복수 염기서열 정렬문제에 적용하였다. 본 논문에서는 genetic algorithm의 design과 적용방법을 기술하였다. 본 연구에서 제안된 genetic algorithm을 사용하여 dynamic programming의 단점이었던 오랜 실행시간을 줄일 수 있었으며, dynamic programming이 제공하지 못하는 최적의 염기서열 정렬을 제공할 수 있었다.

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Phylogeny, host-parasite relationship and zoogeography

  • Hasegawa, Hideo
    • Parasites, Hosts and Diseases
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    • v.37 no.4
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    • pp.197-213
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    • 1999
  • Phylogeny is the evolutionary history of a group or the lineage of organisms and is reconstructed based on morphological, molecular and other characteristics. The genealogical relationship of a group of taxa is often expressed as a phylogenetic tree. The difficulty in categorizing the phylogeny is mainly due to the existence of frequent homoplasies that deceive observers. At the present time, cladistic analysis is believed to be one of the most effective methods of reconstructing a phylogenetic tree. Excellent computer program software for phylogenetic analysis is available. As an example, cladistic analysis was applied for nematode genera of the family Acuariidae, and the phylogenetic tree formed was compared with the system used currently. Nematodes in the genera Nippostrongylus and Heligmonoides were also analyzed, and the validity of the reconstructed phylogenetic trees was observed from a zoogeographical point of view. Some of the theories of parasite evolution were briefly reviewed as well. Coevolution of parasites and humans was discussed with special reference to the evolutionary relationship between Enterobius and primates.

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Aerodynamic Investigation for Prospective Aerospace Vehicle in the Transitional Regime

  • Ivanovich, Khlopkov Yuri;Myint, Zay Yar Myo;Yurievich, Khlopkov Anton
    • International Journal of Aeronautical and Space Sciences
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    • v.14 no.3
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    • pp.215-221
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    • 2013
  • The basic quantitative tool for the study of hypersonic rarefied flows is the direct simulation Monte Carlo method (DSMC). The DSMC method requires a large amount of computer memory and performance and is unreasonably expensive at the first stage of spacecraft design and trajectory analysis. A possible solution to this problem is approximate engineering methods. However, the Monte Carlo method remains the most reliable approach to compare to the engineering methods that provide good results for the global aerodynamic coefficients of various geometry designs. This paper presents the calculation results of aerodynamic characteristics for spacecraft vehicles in the free molecular, the transitional and the continuum regimes using the local engineering method. Results and methods would be useful to calculate aerodynamics for new-generation hypersonic vehicle designs.